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Select item 112772371.

Analysis of Brain, Blood, and Testis Phenotypes Lacking the Vps13a Gene in C57BL/6N Mice

Jitrapa Pinyomahakul, Masataka Ise, Meiko Kawamura, Takashi Yamada, Kentaro Okuyama, Shinsuke Shibata, Jun Takizawa, Manabu Abe, Kenji Sakimura, Hirohide Takebayashi

Int J Mol Sci. 2024 Jul; 25(14): 7776. Published online 2024 Jul 16. doi: 10.3390/ijms25147776

PMCID:: PMC11277237

Article PDF–7.6M

Select item 109176602.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Article PDF–4.8M

Select item 103315843.

AAV induces hepatic necroptosis and carcinoma in diabetic and obese mice dependent on Pebp1 pathway

Yalan Cheng, Zhentong Zhang, Peidong Gao, Hejin Lai, Wuling Zhong, Ning Feng, Yale Yang, Huimin Yu, Yali Zhang, Yumo Han, Jieya Dong, Zhishui He, Rui Huang, Qiwei Zhai

EMBO Mol Med. 2023 Jul; 15(7): e17230. Published online 2023 Jun 5. doi: 10.15252/emmm.202217230

PMCID:: PMC10331584

Article PDF–4.0M

Select item 103078524.

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility

Juan Gu, Pingyang Ke, Haokun Guo, Jing Liu, Yan Liu, Xin Tian, Zhuo Huang, Xin Xu, Demei Xu, Yuanlin Ma, Xuefeng Wang, Fei Xiao

Cell Death Differ. 2023 Jul; 30(7): 1726–1741. Published online 2023 May 4. doi: 10.1038/s41418-023-01174-5

PMCID:: PMC10307852

Article PDF–8.8M

Select item 102189875.

Direct Enhancement Effect of Hippocampal Cholinergic Neurostimulating Peptide on Cholinergic Activity in the Hippocampus

Yuta Madokoro, Daisuke Kato, Yo Tsuda, Itsumi Arakawa, Kengo Suzuki, Toyohiro Sato, Masayuki Mizuno, Yuto Uchida, Kosei Ojika, Noriyuki Matsukawa

Int J Mol Sci. 2023 May; 24(10): 8916. Published online 2023 May 17. doi: 10.3390/ijms24108916

PMCID:: PMC10218987

Article PDF–908K

Select item 97285086.

RKIP suppresses the influenza A virus-induced airway inflammatory response via the ERK/MAPK pathway

Jing-Jing Ye, Si-Liang Wei, Yuan-Yuan Wei, Da-Wei Zhang, Li Sun, Hui-Mei Wu, Ji-Long Shen, Li Yu, Yong Wang, Guang-He Fei

Int J Mol Med. 2023 Jan; 51(1): 1. Published online 2022 Nov 16. doi: 10.3892/ijmm.2022.5204

PMCID:: PMC9728508

Article PDF–6.8M

Select item 96496367.

Reduction of glutamatergic activity through cholinergic dysfunction in the hippocampus of hippocampal cholinergic neurostimulating peptide precursor protein knockout mice

Kengo Suzuki, Yoshiaki Ohi, Toyohiro Sato, Yo Tsuda, Yuta Madokoro, Masayuki Mizuno, Kenichi Adachi, Yuto Uchida, Akira Haji, Kosei Ojika, Noriyuki Matsukawa

Sci Rep. 2022; 12: 19161. Published online 2022 Nov 10. doi: 10.1038/s41598-022-23846-x

PMCID:: PMC9649636

Article PDF–2.3M

Select item 96038608.

The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3

Laura Sánchez-Bellver, Andrea Férriz-Gordillo, Marc Carrillo-Pz, Laura Rabanal, Francesc R. Garcia-Gonzalo, Gemma Marfany

Int J Mol Sci. 2022 Oct; 23(20): 12527. Published online 2022 Oct 19. doi: 10.3390/ijms232012527

PMCID:: PMC9603860

Article PDF–3.4M

Select item 94819339.

ALS-linked loss of Cyclin-F function affects HSP90

Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends

Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359

PMCID:: PMC9481933

Article PDF–3.5M

Select item 927595410.

Phosphatidylethanolamine-binding protein 1 (PEBP1) mediates the regulatory role of microRNAs (miRNAs)-205-5p in degranulation and histamine release

Yuting Kuang, Binya Hu, Min Huang, Sijun Zhao, Xionghui Wu, Mengping Zhang, Zhong Xie

Bioengineered. 2022; 13(5): 13341–13351. Published online 2022 May 29. doi: 10.1080/21655979.2022.2080387

PMCID:: PMC9275954

Article PDF–2.8M

Select item 901455911.

Functional genomic landscape of cancer-intrinsic evasion of killing by T cells

Keith A. Lawson, Cristovão M. Sousa, Xiaoyu Zhang, Eiru Kim, Rummy Akthar, Joseph J. Caumanns, Yuxi Yao, Nicholas Mikolajewicz, Catherine Ross, Kevin R. Brown, Abdelrahman Abou Zid, Zi Peng Fan, Shirley Hui, Jordan A. Krall, Donald M. Simons, Chloe J. Slater, Victor De Jesus, Lujia Tang, Richa Singh, Joshua E. Goldford, Sarah Martin, Qian Huang, Elizabeth A. Francis, Andrea Habsid, Ryan Climie, David Tieu, Jiarun Wei, Ren Li, Amy Hin Yan Tong, Michael Aregger, Katherine S. Chan, Hong Han, Xiaowei Wang, Patricia Mero, John H. Brumell, Antonio Finelli, Laurie Ailles, Gary Bader, Gromoslaw A. Smolen, Gillian A. Kingsbury, Traver Hart, Charles Kung, Jason Moffat

Nature. Author manuscript; available in PMC 2022 Apr 18.

Published in final edited form as: Nature. 2020 Oct; 586(7827): 120–126. Published online 2020 Sep 23. doi: 10.1038/s41586-020-2746-2

PMCID:: PMC9014559

Article PDF–6.6M

Select item 882849412.

Didymin Suppresses Microglia Pyroptosis and Neuroinflammation Through the Asc/Caspase-1/GSDMD Pathway Following Experimental Intracerebral Hemorrhage

Lingui Gu, Mingjiang Sun, Ruihao Li, Xingyu Zhang, Yihao Tao, Ye Yuan, Xu Luo, Zongyi Xie

Front Immunol. 2022; 13: 810582. Published online 2022 Jan 27. doi: 10.3389/fimmu.2022.810582

PMCID:: PMC8828494

Article PDF–16M

Select item 877622113.

ERK1/2 Activity Is Critical for the Outcome of Ischemic Stroke

Constanze Schanbacher, Michael Bieber, Yvonne Reinders, Deya Cherpokova, Christina Teichert, Bernhard Nieswandt, Albert Sickmann, Christoph Kleinschnitz, Friederike Langhauser, Kristina Lorenz

Int J Mol Sci. 2022 Jan; 23(2): 706. Published online 2022 Jan 9. doi: 10.3390/ijms23020706

PMCID:: PMC8776221

Article PDF–2.7M

Select item 865760914.

Unraveling the Spatiotemporal Distribution of VPS13A in the Mouse Brain

Esther García-García, Nerea Chaparro-Cabanillas, Albert Coll-Manzano, Maria Carreras-Caballé, Albert Giralt, Daniel Del Toro, Jordi Alberch, Mercè Masana, Manuel J. Rodríguez

Int J Mol Sci. 2021 Dec; 22(23): 13018. Published online 2021 Dec 1. doi: 10.3390/ijms222313018

PMCID:: PMC8657609

Article PDF–15M

Select item 858636315.

Reduction of acetylcholine in the hippocampus of hippocampal cholinergic neurostimulating peptide precursor protein knockout mice

Yuko Kondo-Takuma, Masayuki Mizuno, Yo Tsuda, Yuta Madokoro, Kengo Suzuki, Toyohiro Sato, Hiroshi Takase, Yuto Uchida, Ken-ichi Adachi, Hideki Hida, Cesario V. Borlongan, Noriyuki Matsukawa

Sci Rep. 2021; 11: 22072. Published online 2021 Nov 11. doi: 10.1038/s41598-021-01667-8

PMCID:: PMC8586363

Article PDF–1.4M

Select item 831323916.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Article PDF–1.6M

Select item 816379017.

Proteotyping of knockout mouse strains reveals sex- and strain-specific signatures in blood plasma

Yassene Mohammed, Sarah A. Michaud, Helena Pětrošová, Juncong Yang, Milan Ganguly, David Schibli, Ann M. Flenniken, Lauryl M. J. Nutter, Hibret A. Adissu, K. C. Kent Lloyd, Colin McKerlie, Christoph H. Borchers

NPJ Syst Biol Appl. 2021; 7: 25. Published online 2021 May 28. doi: 10.1038/s41540-021-00184-8

PMCID:: PMC8163790

Article PDF–6.9M

Select item 809168718.

Therapeutic targeting of Lyn kinase to treat chorea-acanthocytosis

Kevin Peikert, Enrica Federti, Alessandro Matte, Gabriela Constantin, Enrica Caterina Pietronigro, Paolo Francesco Fabene, Paola Defilippi, Emilia Turco, Federico Del Gallo, Pietro Pucci, Angela Amoresano, Anna Illiano, Flora Cozzolino, Maria Monti, Francesca Garello, Enzo Terreno, Seth Leo Alper, Hannes Glaß, Lisann Pelzl, Katja Akgün, Tjalf Ziemssen, Rainer Ordemann, Florian Lang, Anna Maria Brunati, Elena Tibaldi, Immacolata Andolfo, Achille Iolascon, Giuseppe Bertini, Mario Buffelli, Carlo Zancanaro, Erika Lorenzetto, Angela Siciliano, Massimiliano Bonifacio, Adrian Danek, Ruth Helen Walker, Andreas Hermann, Lucia De Franceschi

Acta Neuropathol Commun. 2021; 9: 81. Published online 2021 May 3. doi: 10.1186/s40478-021-01181-y

PMCID:: PMC8091687

Article PDF–6.7M

Select item 793877019.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Article PDF–2.0M

Select item 741599120.

BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)

Kou Motani, Hidetaka Kosako

J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323

PMCID:: PMC7415991

Article PDF–2.0M

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