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Select item 116340661.

Impaired myofibroblast proliferation is a central feature of pathologic post-natal alveolar simplification

Imran S Khan, Christopher Molina, Xin Ren, Vincent C Auyeung, Max Cohen, Tatsuya Tsukui, Amha Atakilit, Dean Sheppard

eLife. 2024; 13: RP94425. Published online 2024 Dec 11. doi: 10.7554/eLife.94425

PMCID:: PMC11634066

Article PDF–5.3M

Select item 111582702.

Integrin alphavbeta6 mediates the potential for colon cancer cells to colonize in and metastasize to the liver

Guang‐Yun Yang, Ke‐Sen Xu, Zhong‐Qing Pan, Zhao‐Yang Zhang, Yue‐Tang Mi, Jin‐Shen Wang, Rong Chen, Jun Niu

Cancer Sci. 2008 May; 99(5): 879–887. Published online 2008 Feb 20. doi: 10.1111/j.1349-7006.2008.00762.x

PMCID:: PMC11158270

Article PDF–2.0M

Select item 111569283.

Knockout of integrin αvβ6 protects against renal inflammation in chronic kidney disease by reduction of pro-inflammatory macrophages

Changjian Zhu, Ruilin Zheng, Xu Han, Ziwen Tang, Feng Li, Xinrong Hu, Ruoni Lin, Jiani Shen, Qiaoqiao Pei, Rong Wang, Guangyan Wei, Zhenwei Peng, Wei Chen, Zhou Liang, Yi Zhou

Cell Death Dis. 2024 Jun; 15(6): 397. Published online 2024 Jun 6. doi: 10.1038/s41419-024-06785-5

PMCID:: PMC11156928

Article PDF–13M

Select item 103207484.

Runx2 activates hepatic stellate cells to promote liver fibrosis via transcriptionally regulating Itgav expression

Li Zhong, Jinqiu Zhao, Lu Huang, Yi Liu, Xiaoxiao Pang, Ke Zhan, Shan Li, Qian Xue, Xiaoli Pan, Liang Deng

Clin Transl Med. 2023 Jul; 13(7): e1316. Published online 2023 Jul 5. doi: 10.1002/ctm2.1316

PMCID:: PMC10320748

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Select item 102089585.

Impaired OTUD7A-dependent Ankyrin regulation mediates neuronal dysfunction in mouse and human models of the 15q13.3 microdeletion syndrome

Brianna K. Unda, Leon Chalil, Sehyoun Yoon, Savannah Kilpatrick, Courtney Irwin, Sansi Xing, Nadeem Murtaza, Anran Cheng, Chad Brown, Alexandria Afonso, Elizabeth McCready, Gabriel M. Ronen, Jennifer Howe, Aurélie Caye-Eude, Alain Verloes, Brad W. Doble, Laurence Faivre, Antonio Vitobello, Stephen W. Scherer, Yu Lu, Peter Penzes, Karun K. Singh

Mol Psychiatry. 2023; 28(4): 1747–1769. Published online 2023 Jan 6. doi: 10.1038/s41380-022-01937-5

PMCID:: PMC10208958

Article PDF–7.0M

Select item 101785656.

Treadmill Exercise Alleviates Cognition Disorder by Activating the FNDC5: Dual Role of Integrin αV/β5 in Parkinson’s Disease

Chuanxi Tang, Mengting Liu, Zihang Zhou, Hao Li, Chenglin Yang, Li Yang, Jie Xiang

Int J Mol Sci. 2023 May; 24(9): 7830. Published online 2023 Apr 25. doi: 10.3390/ijms24097830

PMCID:: PMC10178565

Article PDF–4.7M

Select item 99382167.

Rescue of neuropsychiatric phenotypes in a mouse model of 16p11.2 duplication syndrome by genetic correction of an epilepsy network hub

Marc P. Forrest, Marc Dos Santos, Nicolas H. Piguel, Yi-Zhi Wang, Nicole A. Hawkins, Vikram A. Bagchi, Leonardo E. Dionisio, Sehyoun Yoon, Dina Simkin, Maria Dolores Martin-de-Saavedra, Ruoqi Gao, Katherine E. Horan, Alfred L. George, Jr., Mark S. LeDoux, Jennifer A. Kearney, Jeffrey N. Savas, Peter Penzes

Nat Commun. 2023; 14: 825. Published online 2023 Feb 17. doi: 10.1038/s41467-023-36087-x

PMCID:: PMC9938216

Article PDF–5.3M

Select item 97910808.

Central Irisin Signaling Is Required for Normal Timing of Puberty in Female Mice

Caroline Decourt, Maggie C Evans, Megan A Inglis, Greg M Anderson

Endocrinology. 2023 Feb; 164(2): bqac208. Published online 2022 Dec 12. doi: 10.1210/endocr/bqac208

PMCID:: PMC9791080

Article

Select item 91199309.

Pericyte-to-endothelial cell signaling via vitronectin-integrin regulates blood-CNS barrier

Swathi Ayloo, Christopher Gallego Lazo, Shenghuan Sun, Wei Zhang, Bianxiao Cui, Chenghua Gu

Neuron. Author manuscript; available in PMC 2023 May 18.

Published in final edited form as: Neuron. 2022 May 18; 110(10): 1641–1655.e6. Published online 2022 Mar 15. doi: 10.1016/j.neuron.2022.02.017

PMCID:: PMC9119930

Article PDF–4.7M

Select item 897710010.

The β8 integrin cytoplasmic domain activates extracellular matrix adhesion to promote brain neurovascular development

Arpan De, John E. Morales, Zhihua Chen, Sumod Sebastian, Joseph H. McCarty

Development. 2022 Mar 15; 149(6): dev200472. Published online 2022 Mar 18. doi: 10.1242/dev.200472

PMCID:: PMC8977100

Article

Select item 878017111.

αVβ3 Integrin Expression Is Essential for Replication of Mosquito and Tick-Borne Flaviviruses in Murine Fibroblast Cells

Vinicius Pinho dos Reis, Markus Keller, Katja Schmidt, Rainer Günter Ulrich, Martin Hermann Groschup

Viruses. 2022 Jan; 14(1): 18. Published online 2021 Dec 23. doi: 10.3390/v14010018

PMCID:: PMC8780171

Article PDF–2.7M

Select item 855394212.

Regulatory T cells promote cancer immune-escape through integrin αvβ8-mediated TGF-β activation

Alexandra Lainé, Ossama Labiad, Hector Hernandez-Vargas, Sébastien This, Amélien Sanlaville, Sophie Léon, Stéphane Dalle, Dean Sheppard, Mark A. Travis, Helena Paidassi, Julien C. Marie

Nat Commun. 2021; 12: 6228. Published online 2021 Oct 28. doi: 10.1038/s41467-021-26352-2

PMCID:: PMC8553942

Article PDF–3.2M

Select item 843124913.

αV Integrin Expression and Localization in Male Germ Cells

Veronika Palenikova, Michaela Frolikova, Eliska Valaskova, Pavla Postlerova, Katerina Komrskova

Int J Mol Sci. 2021 Sep; 22(17): 9525. Published online 2021 Sep 2. doi: 10.3390/ijms22179525

PMCID:: PMC8431249

Article PDF–2.1M

Select item 832141414.

Integrin αvβ8 on T cells suppresses anti-tumor immunity in multiple models and is a promising target for tumor immunotherapy

Eswari Dodagatta-Marri, Hsiao-Yen Ma, Benjia Liang, John Li, Dominique S. Meyer, Szu-Ying Chen, Kai-Hui Sun, Xin Ren, Bahar Zivak, Michael D. Rosenblum, Mark B. Headley, Lauren Pinzas, Nilgun I. Reed, Joselyn S. Del Cid, Byron C. Hann, Sharon Yang, Anand Giddabasappa, Kavon Noorbehesht, Bing Yang, Joseph Dal Porto, Tatsuya Tsukui, Kyle Niessen, Amha Atakilit, Rosemary J. Akhurst, Dean Sheppard

Cell Rep. Author manuscript; available in PMC 2021 Jul 29.

Published in final edited form as: Cell Rep. 2021 Jul 6; 36(1): 109309. doi: 10.1016/j.celrep.2021.109309

PMCID:: PMC8321414

Article PDF–2.3M

Select item 831323915.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Article PDF–1.6M

Select item 828510816.

Action potential-coupled Rho GTPase signaling drives presynaptic plasticity

Shataakshi Dube O'Neil, Bence Rácz, Walter Evan Brown, Yudong Gao, Erik J Soderblom, Ryohei Yasuda, Scott H Soderling

eLife. 2021; 10: e63756. Published online 2021 Jul 16. doi: 10.7554/eLife.63756

PMCID:: PMC8285108

Article PDF–13M

Select item 810630617.

Autoregulation of insulin receptor signaling through MFGE8 and the αvβ5 integrin

Ritwik Datta, Carlos O. Lizama, Amin K. Soltani, William Mckleroy, Michael J. Podolsky, Christopher D. Yang, Tony L. Huynh, Kelly M. Cautivo, Biao Wang, Suneil K. Koliwad, Nada A. Abumrad, Kamran Atabai

Proc Natl Acad Sci U S A. 2021 May 4; 118(18): e2102171118. Published online 2021 Apr 26. doi: 10.1073/pnas.2102171118

PMCID:: PMC8106306

Article PDF–2.4M

Select item 808511918.

Apoptotic cells in mouse blastocysts are eliminated by neighbouring blastomeres

Jozef Pisko, Alexandra Špirková, Štefan Čikoš, Lucia Olexiková, Veronika Kovaříková, Zuzana Šefčíková, Dušan Fabian

Sci Rep. 2021; 11: 9228. Published online 2021 Apr 29. doi: 10.1038/s41598-021-88752-0

PMCID:: PMC8085119

Article PDF–1.6M

Select item 801959619.

Tsg101 Is Necessary for the Establishment and Maintenance of Mouse Retinal Pigment Epithelial Cell Polarity

Dai Le, Soyeon Lim, Kwang Wook Min, Joon Woo Park, Youjoung Kim, Taejeong Ha, Kyeong Hwan Moon, Kay-Uwe Wagner, Jin Woo Kim

Mol Cells. 2021 Mar 31; 44(3): 168–178. Published online 2021 Mar 28. doi: 10.14348/molcells.2021.0027

PMCID:: PMC8019596

Article PDF–34M

Select item 796974120.

Mechanical stress determines the configuration of TGFβ activation in articular cartilage

Gehua Zhen, Qiaoyue Guo, Yusheng Li, Chuanlong Wu, Shouan Zhu, Ruomei Wang, X. Edward Guo, Byoung Choul Kim, Jessie Huang, Yizhong Hu, Yang Dan, Mei Wan, Taekjip Ha, Steven An, Xu Cao

Nat Commun. 2021; 12: 1706. Published online 2021 Mar 17. doi: 10.1038/s41467-021-21948-0

PMCID:: PMC7969741

Article PDF–3.4M

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