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Items: 1 to 20 of 138

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
The ubiquitin ligases Cbl and Cbl-b regulate macrophage growth by controlling CSF-1R import into macropinosomes
Lu Huang, Natalie W. Thiex, Jieqiong Lou, Gulzar Ahmad, Wei An, Shalini T. Low-Nam, Jason G. Kerkvliet, Hamid Band, Adam D. Hoppe
Mol Biol Cell. 2024 Mar 1; 35(3): ar38. Published online 2024 Feb 2. doi: 10.1091/mbc.E23-09-0345
PMCID:
PMC10916879
AbstractArticlePDF–2.4M
3.
PRL2 phosphatase promotes oncogenic KIT signaling in leukemia cells through modulating CBL phosphorylation
Hongxia Chen, Yunpeng Bai, Michihiro Kobayashi, Shiyu Xiao, Sergio Barajas, Wenjie Cai, Sisi Chen, Jinmin Miao, Frederick Nguele Meke, Chonghua Yao, Yuxia Yang, Katherine Strube, Odelia Satchivi, Jianmin Sun, Lars Rönnstrand, James M. Croop, H. Scott Boswell, Yuzhi Jia, Huiping Liu, Loretta S. Li, Jessica K. Altman, Elizabeth A. Eklund, Madina Sukhanova, Peng Ji, Wei Tong, Hamid Band, Danny T. Huang, Leonidas C. Platanias, Zhong-Yin Zhang, Yan Liu
Mol Cancer Res. Author manuscript; available in PMC 2024 Jul 2.
Published in final edited form as: Mol Cancer Res. 2024 Jan 2; 22(1): 94–103. doi: 10.1158/1541-7786.MCR-23-0115
PMCID:
PMC10841656
AbstractArticlePDF–2.1M
4.
c-Cbl Regulates Murine Subventricular Zone-Derived Neural Progenitor Cells in Dependence of the Epidermal Growth Factor Receptor
Maximilian Vogt, Madhukrishna Kolothara Unnikrishnan, Nora Heinig, Ulrike Schumann, Mirko H. H. Schmidt, Kathrin Barth
Cells. 2023 Oct; 12(19): 2400. Published online 2023 Oct 3. doi: 10.3390/cells12192400
PMCID:
PMC10572332
AbstractArticlePDF–5.9M
5.
CBL/CAP Is Essential for Mitochondria Respiration Complex I Assembly and Bioenergetics Efficiency in Muscle Cells
Cho-Cho Aye, Dean E. Hammond, Sergio Rodriguez-Cuenca, Mary K. Doherty, Phillip D. Whitfield, Marie M. Phelan, Chenjing Yang, Rafael Perez-Perez, Xiaoxin Li, Angels Diaz-Ramos, Gopal Peddinti, Matej Oresic, Antonio Vidal-Puig, Antonio Zorzano, Cristina Ugalde, Silvia Mora
Int J Mol Sci. 2023 Feb; 24(4): 3399. Published online 2023 Feb 8. doi: 10.3390/ijms24043399
PMCID:
PMC9964740
AbstractArticlePDF–2.4M
6.
Hematopoietic Stem/Progenitor Cells Exhibit Stage-Specific Translational Programs via mTOR-and CDK1-dependent Mechanisms
Christina C. Spevak, Harold K. Elias, Lavanya Kannan, Mohamed A.E. Ali, Gaëlle H. Martin, Shanmugapriya Selvaraj, William S. Eng, Amanda Ernlund, Vinagolu K. Rajasekhar, Carolien M. Woolthuis, Guangjie Zhao, Caryn J. Ha, Robert J. Schneider, Christopher Y. Park
Cell Stem Cell. Author manuscript; available in PMC 2022 Sep 1.
Published in final edited form as: Cell Stem Cell. 2020 May 7; 26(5): 755–765.e7. doi: 10.1016/j.stem.2019.12.006
PMCID:
PMC9435590
AbstractArticlePDF–1.6M
7.
Ubiquitin Ligases CBL and CBL-B Maintain the Homeostasis and Immune Quiescence of Dendritic Cells
Haijun Tong, Xin Li, Jinping Zhang, Liying Gong, Weili Sun, Virginie Calderon, Xiaochen Zhang, Yue Li, Adeline Gadzinski, Wallace Y. Langdon, Boris Reizis, Yongrui Zou, Hua Gu
Front Immunol. 2021; 12: 757231. Published online 2021 Sep 23. doi: 10.3389/fimmu.2021.757231
PMCID:
PMC8494778
AbstractArticlePDF–3.6M
8.
C-CBL is required for inhibition of angiogenesis through modulating JAK2/STAT3 activity in ROP development
Shimei Chen, Qiao Sun, Dandan Sun, Jami Willette-Brown, Matthew J. Anderson, Qing Gu, Mark Lewandoski, Yinling Hu, Feng Zhu, Fang Wei, Jian Zhang
Biomed Pharmacother. Author manuscript; available in PMC 2021 Aug 4.
Published in final edited form as: Biomed Pharmacother. 2020 Dec; 132: 110856. Published online 2020 Oct 28. doi: 10.1016/j.biopha.2020.110856
PMCID:
PMC8336301
AbstractArticlePDF–1.0M
9.
E3 ligase c-Cbl regulates intestinal inflammation through suppressing fungi-induced noncanonical NF-κB activation
Jie-Lin Duan, Hui-Qian He, Yao Yu, Tao Liu, Shu-Jun Ma, Fan Li, Yan-Shan Jiang, Xin Lin, De-Dong Li, Quan-Zhen Lv, Hui-Hui Ma, Xin-Ming Jia
Sci Adv. 2021 May; 7(19): eabe5171. Published online 2021 May 7. doi: 10.1126/sciadv.abe5171
PMCID:
PMC8104877
AbstractArticlePDF–9.3M
10.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
11.
C‐Cbl regulates c‐MPL receptor trafficking and its internalization
Melanie Märklin, Claudia Tandler, Hans‐Georg Kopp, Kyle L. Hoehn, Leticia Quintanilla‐Martinez, Oliver Borst, Martin R. Müller, Sebastian J. Saur
J Cell Mol Med. 2020 Nov; 24(21): 12491–12503. Published online 2020 Sep 20. doi: 10.1111/jcmm.15785
PMCID:
PMC7687000
AbstractArticlePDF–1.7M
12.
Cbl and Cbl-b control the germinal center reaction by facilitating naive B cell antigen processing
Xin Li, Liying Gong, Alexandre P. Meli, Danielle Karo-Atar, Weili Sun, Yongrui Zou, Irah L. King, Hua Gu
J Exp Med. 2020 Sep 7; 217(9): e20191537. Published online 2020 Jun 25. doi: 10.1084/jem.20191537
PMCID:
PMC7478728
AbstractArticlePDF–6.0M
13.
BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)
Kou Motani, Hidetaka Kosako
J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323
PMCID:
PMC7415991
AbstractArticlePDF–2.0M
14.
Evolution of an Amniote-Specific Mechanism for Modulating Ubiquitin Signaling via Phosphoregulation of the E2 Enzyme UBE2D3
Monica Roman-Trufero, Constance M Ito, Conrado Pedebos, Indiana Magdalou, Yi-Fang Wang, Mohammad M Karimi, Benjamin Moyon, Zoe Webster, Aida di Gregorio, Veronique Azuara, Syma Khalid, Christian Speck, Tristan Rodriguez, Niall Dillon
Mol Biol Evol. 2020 Jul; 37(7): 1986–2001. Published online 2020 Mar 12. doi: 10.1093/molbev/msaa060
PMCID:
PMC7306689
AbstractArticlePDF–2.3M
15.
Haploinsufficiency of Casitas B-Lineage Lymphoma Augments the Progression of Colon Cancer in the Background of Adenomatous Polyposis Coli Inactivation
Sean Richards, Joshua Walker, Masako Nakanishi, Mostafa Belghasem, Chimera Lyle, Nkiruka Arinze, Marc A. Napoleon, Jonathan D. Ravid, Nicholas Crossland, Qing Zhao, Daniel Rosenberg, Nader Rahimi, Vipul C. Chitalia
Am J Pathol. 2020 Mar; 190(3): 602–613. doi: 10.1016/j.ajpath.2019.10.024
PMCID:
PMC7074366
AbstractArticlePDF–4.4M
16.
Quantitative interactomics in primary T cells unveils TCR signal diversification extent and dynamics
Guillaume Voisinne, Kristof Kersse, Karima Chaoui, Liaoxun Lu, Julie Chaix, Lichen Zhang, Marisa Goncalves Menoita, Laura Girard, Youcef Ounoughene, Hui Wang, Odile Burlet-Schiltz, Hervé Luche, Frédéric Fiore, Marie Malissen, Anne Gonzalez de Peredo, Yinming Liang, Romain Roncagalli, Bernard Malissen
Nat Immunol. Author manuscript; available in PMC 2020 Apr 7.
Published in final edited form as: Nat Immunol. 2019 Nov 1; 20(11): 1530–1541. Published online 2019 Oct 7. doi: 10.1038/s41590-019-0489-8
PMCID:
PMC6859066
AbstractArticlePDF–2.9M
17.
A PDGFRβ-PI3K signaling axis mediates periosteal cell activation during fracture healing
Laura Doherty, Jungeun Yu, Xi Wang, Kurt D. Hankenson, Ivo Kalajzic, Archana Sanjay
PLoS One. 2019; 14(10): e0223846. Published online 2019 Oct 30. doi: 10.1371/journal.pone.0223846
PMCID:
PMC6821073
AbstractArticlePDF–1.9M
18.
Cbl-PI3K Interaction Regulates Cathepsin K Secretion in Osteoclasts
Jungeun Yu, Naga Suresh Adapala, Laura Doherty, Archana Sanjay
Bone. Author manuscript; available in PMC 2020 Oct 1.
Published in final edited form as: Bone. 2019 Oct; 127: 376–385. Published online 2019 Jul 9. doi: 10.1016/j.bone.2019.07.009
PMCID:
PMC6708784
AbstractArticlePDF–1.4M
19.
Unique-region phosphorylation targets LynA for rapid degradation, tuning its expression and signaling in myeloid cells
Ben F Brian, IV, Adrienne S Jolicoeur, Candace R Guerrero, Myra G Nunez, Zoi E Sychev, Siv A Hegre, Pål Sætrom, Nagy Habib, Justin M Drake, Kathryn L Schwertfeger, Tanya S Freedman
eLife. 2019; 8: e46043. Published online 2019 Jul 8. doi: 10.7554/eLife.46043
PMCID:
PMC6660195
AbstractArticlePDF–2.1M
20.
Loss of function Cbl-c mutations in solid tumors
Silvano Rakeem Daniels, Mariya Liyasova, Stephen C. Kales, Marion M. Nau, Philip E. Ryan, Jeffrey E. Green, Stanley Lipkowitz
PLoS One. 2019; 14(7): e0219143. Published online 2019 Jul 1. doi: 10.1371/journal.pone.0219143
PMCID:
PMC6602201
AbstractArticlePDF–2.7M

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