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Items: 1 to 20 of 61

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Acute Inhibition of Intestinal Neprilysin Enhances Insulin Secretion via GLP-1 Receptor Signaling in Male Mice
Nathalie Esser, Thomas O Mundinger, Breanne M Barrow, Sakeneh Zraika
Endocrinology. 2023 May; 164(5): bqad055. Published online 2023 Mar 25. doi: 10.1210/endocr/bqad055
PMCID:
PMC10282919
AbstractArticle
3.
Neprilysin-dependent neuropeptide Y cleavage in the liver promotes fibrosis by blocking NPY-receptor 1
Cristina Ortiz, Sabine Klein, Winfried H. Reul, Fernando Magdaleno, Stefanie Gröschl, Peter Dietrich, Robert Schierwagen, Frank E. Uschner, Sandra Torres, Christoph Hieber, Caroline Meier, Nico Kraus, Olaf Tyc, Maximilian Brol, Stefan Zeuzem, Christoph Welsch, Marco Poglitsch, Claus Hellerbrand, Mercedes Alfonso-Prieto, Fabio Mira, Ulrich auf dem Keller, Anja Tetzner, Andrew Moore, Thomas Walther, Jonel Trebicka
Cell Rep. 2023 Feb 28; 42(2): 112059. Published online 2023 Jan 31. doi: 10.1016/j.celrep.2023.112059
PMCID:
PMC9989826
AbstractArticle
4.
SOX9 and SOX10 control fluid homeostasis in the inner ear for hearing through independent and cooperative mechanisms
Irene Y. Y. Szeto, Daniel K. H. Chu, Peikai Chen, Ka Chi Chu, Tiffany Y. K. Au, Keith K. H. Leung, Yong-Heng Huang, Sarah L. Wynn, Angel C. Y. Mak, Ying-Shing Chan, Wood Yee Chan, Ralf Jauch, Bernd Fritzsch, Mai Har Sham, Robin Lovell-Badge, Kathryn S. E. Cheah
Proc Natl Acad Sci U S A. 2022 Nov 15; 119(46): e2122121119. Published online 2022 Nov 7. doi: 10.1073/pnas.2122121119
PMCID:
PMC9674217
AbstractArticlePDF–2.7M
5.
Peroxisome Metabolism Contributes to PIEZO2-Mediated Mechanical Allodynia
Yi Gong, Fiza Laheji, Anna Berenson, April Qian, Sang-O Park, Rene Kok, Martin Selig, Ryan Hahn, Reza Sadjadi, Stephan Kemp, Florian Eichler
Cells. 2022 Jun; 11(11): 1842. Published online 2022 Jun 4. doi: 10.3390/cells11111842
PMCID:
PMC9180358
AbstractArticlePDF–4.6M
6.
Loss of zinc-finger protein 212 leads to Purkinje cell death and locomotive abnormalities with phospholipase D3 downregulation
Rin Khang, Areum Jo, Hojin Kang, Hanna Kim, Eunsang Kwag, Ji-Yeong Lee, Okjae Koo, Jinsu Park, Hark Kyun Kim, Dong-Gyu Jo, Inwoo Hwang, Jee-Yin Ahn, Yunjong Lee, Jeong-Yun Choi, Yun-Song Lee, Joo-Ho Shin
Sci Rep. 2021; 11: 22745. Published online 2021 Nov 23. doi: 10.1038/s41598-021-02218-x
PMCID:
PMC8610974
AbstractArticlePDF–2.5M
7.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
8.
The Type 3 Deiodinase Is a Critical Modulator of Thyroid Hormone Sensitivity in the Fetal Brain
Maria Elena Martinez, Arturo Hernandez
Front Neurosci. 2021; 15: 703730. Published online 2021 Jun 29. doi: 10.3389/fnins.2021.703730
PMCID:
PMC8265566
AbstractArticlePDF–8.3M
9.
Brain angiotensin‐converting enzymes: role of angiotensin‐converting enzyme 2 in processing angiotensin II in mice
Khalid M. Elased, Tatiana Sousa Cunha, Fernanda Klein Marcondes, Mariana Morris
Exp Physiol. 2008 May; 93(5): 665–675. Published online 2008 Mar 27. doi: 10.1113/expphysiol.2007.040311
PMCID:
PMC7197900
AbstractArticlePDF–197K
10.
Effect of hyperglycemia and rosiglitazone on renal and urinary neprilysin in db/db diabetic mice
Laale F. Alawi, Sana E. Emberesh, Brenda A. Owuor, Harshita Chodavarapu, Rucha Fadnavis, Salim S. El‐Amouri, Khalid M. Elased
Physiol Rep. 2020 Feb; 8(3): e14364. Published online 2020 Feb 5. doi: 10.14814/phy2.14364
PMCID:
PMC7002536
AbstractArticlePDF–1.4M
11.
Membrane metallo‐endopeptidase is dispensable for repair after nerve injury
Ilaria Cervellini, Jorge Galino, Ning Zhu, Florence R. Fricker, Lu Bao, David L. H. Bennett
Glia. 2019 Oct; 67(10): 1990–2000. Published online 2019 Jul 24. doi: 10.1002/glia.23680
PMCID:
PMC6771530
AbstractArticlePDF–5.0M
12.
Presynaptic Localization of Neprilysin Contributes to Efficient Clearance of Amyloid-β Peptide in Mouse Brain
Nobuhisa Iwata, Hiroaki Mizukami, Keiro Shirotani, Yoshie Takaki, Shin-ichi Muramatsu, Bao Lu, Norma P. Gerard, Craig Gerard, Keiya Ozawa, Takaomi C. Saido
J Neurosci. 2004 Jan 28; 24(4): 991–998. doi: 10.1523/JNEUROSCI.4792-03.2004
PMCID:
PMC6729819
AbstractArticlePDF–740K
13.
BIOCHEMISTRY, THERAPEUTICS AND BIOMARKER IMPLICATIONS OF NEPRILYSIN IN CARDIORENAL DISEASE
Yang Chen, John C. Burnett, Jr
Clin Chem. Author manuscript; available in PMC 2019 Jul 8.
Published in final edited form as: Clin Chem. 2017 Jan; 63(1): 108–115. Published online 2016 Nov 15. doi: 10.1373/clinchem.2016.262907
PMCID:
PMC6613397
AbstractArticlePDF–741K
14.
Apelin protects against abdominal aortic aneurysm and the therapeutic role of neutral endopeptidase resistant apelin analogs
Wang Wang, Mengcheng Shen, Conrad Fischer, Ratnadeep Basu, Saugata Hazra, Pierre Couvineau, Manish Paul, Faqi Wang, Sandra Toth, Doran S. Mix, Marko Poglitsch, Norma P. Gerard, Michel Bouvier, John C. Vederas, Josef M. Penninger, Zamaneh Kassiri, Gavin Y. Oudit
Proc Natl Acad Sci U S A. 2019 Jun 25; 116(26): 13006–13015. Published online 2019 Jun 12. doi: 10.1073/pnas.1900152116
PMCID:
PMC6600956
AbstractArticlePDF–2.7M
15.
Neprilysin inhibition promotes corneal wound healing
Rachel M. Genova, Kacie J. Meyer, Michael G. Anderson, Matthew M. Harper, Andrew A. Pieper
Sci Rep. 2018; 8: 14385. Published online 2018 Sep 26. doi: 10.1038/s41598-018-32773-9
PMCID:
PMC6158251
AbstractArticlePDF–11M
16.
Neprilysin Deficiency Is Associated With Expansion of Islet β-Cell Mass in High Fat-Fed Mice
Jacqueline H. Parilla, Rebecca L. Hull, Sakeneh Zraika
J Histochem Cytochem. 2018 Jul; 66(7): 523–530. Published online 2018 Mar 19. doi: 10.1369/0022155418765164
PMCID:
PMC6055259
AbstractArticlePDF–8.1M
17.
Sustained Activation of RhoGTPases Promotes a Synthetic Pulmonary Artery Smooth Muscle Cell Phenotype in Neprilysin Null Mice
Vijaya Karoor, Mehdi A. Fini, Zoe Loomis, Timothy Sullivan, Louis B. Hersh, Evgenia Gerasimovskaya, David Irwin, Edward C. Dempsey
Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2019 Jan 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2018 Jan; 38(1): 154–163. Published online 2017 Nov 30. doi: 10.1161/ATVBAHA.117.310207
PMCID:
PMC5746466
AbstractArticlePDF–966K
18.
Neprilysin Is Required for Angiotensin-(1–7)’s Ability to Enhance Insulin Secretion via Its Proteolytic Activity to Generate Angiotensin-(1–2)
Gurkirat S. Brar, Breanne M. Barrow, Matthew Watson, Ryan Griesbach, Edwina Choung, Andrew Welch, Bela Ruzsicska, Daniel P. Raleigh, Sakeneh Zraika
Diabetes. 2017 Aug; 66(8): 2201–2212. Published online 2017 May 30. doi: 10.2337/db16-1318
PMCID:
PMC5521860
AbstractArticlePDF–1.7M
19.
Improved glycaemia in high-fat fed neprilysin-deficient mice is associated with reduced DPP-4 activity and increased active GLP-1 levels
Joshua R. Willard, Breanne M. Barrow, Sakeneh Zraika
Diabetologia. Author manuscript; available in PMC 2018 Apr 1.
Published in final edited form as: Diabetologia. 2017 Apr; 60(4): 701–708. Published online 2016 Dec 8. doi: 10.1007/s00125-016-4172-4
PMCID:
PMC5342915
AbstractArticlePDF–1.5M
20.
Rare Variants in MME, Encoding Metalloprotease Neprilysin, Are Linked to Late-Onset Autosomal-Dominant Axonal Polyneuropathies
Michaela Auer-Grumbach, Stefan Toegel, Maria Schabhüttl, Daniela Weinmann, Catharina Chiari, David L.H. Bennett, Christian Beetz, Dennis Klein, Peter M. Andersen, Ilka Böhme, Regina Fink-Puches, Michael Gonzalez, Matthew B. Harms, William Motley, Mary M. Reilly, Wilfried Renner, Sabine Rudnik-Schöneborn, Beate Schlotter-Weigel, Andreas C. Themistocleous, Jochen H. Weishaupt, Albert C. Ludolph, Thomas Wieland, Feifei Tao, Lisa Abreu, Reinhard Windhager, Manuela Zitzelsberger, Tim M. Strom, Thomas Walther, Steven S. Scherer, Stephan Züchner, Rudolf Martini, Jan Senderek
Am J Hum Genet. 2016 Sep 1; 99(3): 607–623. Published online 2016 Sep 1. doi: 10.1016/j.ajhg.2016.07.008
PMCID:
PMC5011077
AbstractArticlePDF–1.6M

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