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Select item 111155971.

The metazoan ATAC and SAGA coactivator HAT complexes regulate different sets of inducible target genes

Zita Nagy, Anne Riss, Sally Fujiyama, Arnaud Krebs, Meritxell Orpinell, Pascal Jansen, Adrian Cohen, Henk G. Stunnenberg, Shigeaki Kato, Làszlò Tora

Cell Mol Life Sci. 2010 Feb; 67(4): 611–628. Published online 2009 Nov 21. doi: 10.1007/s00018-009-0199-8

PMCID:: PMC11115597

Abstract Article PDF–816K

Select item 91036462.

The Ash2l SDI Domain Is Required to Maintain the Stability and Binding of DPY30

Mengjie Ma, Jiafeng Zhou, Zhihua Ma, Hanxue Chen, Liang Li, Lin Hou, Bin Yin, Boqin Qiang, Pengcheng Shu, Xiaozhong Peng

Cells. 2022 May; 11(9): 1450. Published online 2022 Apr 25. doi: 10.3390/cells11091450

PMCID:: PMC9103646

Abstract Article PDF–2.4M

Select item 85812033.

p53 inactivation unmasks histone methylation-independent WDR5 functions that drive self-renewal and differentiation of pluripotent stem cells

Qiang Li, Yuanhao Huang, Jing Xu, Fengbiao Mao, Bo Zhou, Lichao Sun, Brian W. Basinski, Michael Aksu, Jie Liu, Yali Dou, Rajesh C. Rao

Stem Cell Reports. 2021 Nov 9; 16(11): 2642–2658. Published online 2021 Oct 28. doi: 10.1016/j.stemcr.2021.10.002

PMCID:: PMC8581203

Abstract Article PDF–3.5M

Select item 83132394.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 79387705.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 72611496.

Mll-COMPASS complexes mediate H3K4me3 enrichment and transcription of the osteoblast master gene Runx2/p57 in osteoblasts

Adriana Rojas, Hugo Sepulveda, Berta Henriquez, Rodrigo Aguilar, Tatiana Opazo, Gino Nardocci, Fernando Bustos, Jane B. Lian, Janet L. Stein, Gary S. Stein, Brigitte van Zundert, Andre J. van Wijnen, Miguel L. Allende, Martin Montecino

J Cell Physiol. Author manuscript; available in PMC 2020 May 30.

Published in final edited form as: J Cell Physiol. 2019 May; 234(5): 6244–6253. Published online 2018 Sep 7. doi: 10.1002/jcp.27355

PMCID:: PMC7261149

Abstract Article PDF–706K

Select item 66023007.

New roles for the de-ubiquitylating enzyme OTUD4 in an RNA–protein network and RNA granules

Richa Das, Lukas Schwintzer, Stanislav Vinopal, Eva Aguado Roca, Marc Sylvester, Ana-Maria Oprisoreanu, Susanne Schoch, Frank Bradke, Meike Broemer

J Cell Sci. 2019 Jun 15; 132(12): jcs229252. Published online 2019 Jun 17. doi: 10.1242/jcs.229252

PMCID:: PMC6602300

Abstract Article

Select item 50351448.

Pask integrates hormonal signaling with histone modification via Wdr5 phosphorylation to drive myogenesis

Chintan K Kikani, Xiaoying Wu, Litty Paul, Hana Sabic, Zuolian Shen, Arvind Shakya, Alexandra Keefe, Claudio Villanueva, Gabrielle Kardon, Barbara Graves, Dean Tantin, Jared Rutter

eLife. 2016; 5: e17985. Published online 2016 Sep 23. doi: 10.7554/eLife.17985

PMCID:: PMC5035144

Abstract Article PDF–2.1M

Select item 49724599.

Cbx8 acts non-canonically with Wdr5 to promote mammary tumorigenesis

Chi-Yeh Chung, Zhen Sun, Gavriel Mullokandov, Almudena Bosch, Zulekha A. Qadeer, Esma Cihan, Zachary Rapp, Ramon Parsons, Julio A. Aguirre-Ghiso, Eduardo F. Farias, Brian D. Brown, Alexandre Gaspar-Maia, Emily Bernstein

Cell Rep. Author manuscript; available in PMC 2016 Aug 3.

Published in final edited form as: Cell Rep. 2016 Jul 12; 16(2): 472–486. Published online 2016 Jun 23. doi: 10.1016/j.celrep.2016.06.002

PMCID:: PMC4972459

Abstract Article PDF–2.6M

Select item 469194810.

Elf5-centered transcription factor hub controls trophoblast stem cell self-renewal and differentiation through stoichiometry-sensitive shifts in target gene networks

Paulina A. Latos, Arnold R. Sienerth, Alexander Murray, Claire E. Senner, Masanaga Muto, Masahito Ikawa, David Oxley, Sarah Burge, Brian J. Cox, Myriam Hemberger

Genes Dev. 2015 Dec 1; 29(23): 2435–2448. doi: 10.1101/gad.268821.115

PMCID:: PMC4691948

Abstract Article PDF–1.0M

Select item 468613611.

Systematic Identification of Factors for Provirus Silencing in Embryonic Stem Cells

Bin Xia Yang, Chadi A. EL Farran, Hong Chao Guo, Tao Yu, Hai Tong Fang, Hao Fei Wang, Sharon Schlesinger, Yu Fen Samantha Seah, Germaine Yen Lin Goh, Suat Peng Neo, Yinghui Li, Matthew C. Lorincz, Vinay Tergaonkar, Tit-Meng Lim, Lingyi Chen, Jayantha Gunaratne, James J. Collins, Stephen P. Goff, George Q. Daley, Hu Li, Frederic A. Bard, Yuin-Han Loh

Cell. Author manuscript; available in PMC 2015 Dec 21.

Published in final edited form as: Cell. 2015 Sep 24; 163(1): 230–245. Published online 2015 Sep 10. doi: 10.1016/j.cell.2015.08.037

PMCID:: PMC4686136

Abstract Article PDF–1.2M

Select item 462398312.

The TrxG Complex Mediates Cytokine Induced De Novo Enhancer Formation in Islets

Bryan R. Tennant, Peter Hurley, Jasmine Dhillon, Amol Gill, Cheryl Whiting, Brad G. Hoffman

PLoS One. 2015; 10(10): e0141470. Published online 2015 Oct 27. doi: 10.1371/journal.pone.0141470

PMCID:: PMC4623983

Abstract Article PDF–2.4M

Select item 461397913.

MLL3 and MLL4 Methyltransferases Bind to the MAFA and MAFB Transcription Factors to Regulate Islet β-Cell Function

David W. Scoville, Holly A. Cyphert, Lan Liao, Jianming Xu, Al Reynolds, Shuangli Guo, Roland Stein

Diabetes. 2015 Nov; 64(11): 3772–3783. Published online 2015 Jul 15. doi: 10.2337/db15-0281

PMCID:: PMC4613979

Abstract Article PDF–1.5M

Select item 451183314.

Pharmacological targeting of the Wdr5-MLL interaction in C/EBPa N-terminal leukemia

Florian Grebien, Masoud Vedadi, Matthäus Getlik, Roberto Giambruno, Amit Grover, Roberto Avellino, Anna Skucha, Sarah Vittori, Ekaterina Kuznetsova, David Smil, Dalia Barsyte-Lovejoy, Fengling Li, Gennadiy Poda, Matthieu Schapira, Hong Wu, Aiping Dong, Guillermo Senisterra, Alexey Stukalov, Kilian V. M. Huber, Andreas Schönegger, Richard Marcellus, Martin Bilban, Christoph Bock, Peter J. Brown, Johannes Zuber, Keiryn L. Bennett, Rima Al-awar, Ruud Delwel, Claus Nerlov, Cheryl H. Arrowsmith, Giulio Superti-Furga

Nat Chem Biol. Author manuscript; available in PMC 2016 Feb 1.

Published in final edited form as: Nat Chem Biol. 2015 Aug; 11(8): 571–578. Published online 2015 Jul 13. doi: 10.1038/nchembio.1859

PMCID:: PMC4511833

Abstract Article PDF–2.2M

Select item 442752415.

Interaction with WDR5 Promotes Target Gene Recognition and Tumorigenesis by MYC

Lance R. Thomas, Qingguo Wang, Brian C. Grieb, Jason Phan, Audra M. Foshage, Qi Sun, Edward T. Olejniczak, Travis Clark, Soumyadeep Dey, Shelly Lorey, Bethany Alicie, Gregory C. Howard, Bryan Cawthon, Kevin C. Ess, Christine M. Eischen, Zhongming Zhao, Stephen W. Fesik, William P. Tansey

Mol Cell. Author manuscript; available in PMC 2016 May 7.

Published in final edited form as: Mol Cell. 2015 May 7; 58(3): 440–452. Published online 2015 Mar 26. doi: 10.1016/j.molcel.2015.02.028

PMCID:: PMC4427524

Abstract Article PDF–1.7M

Select item 419788216.

BIG3 inhibits insulin granule biogenesis and insulin secretion

Hongyu Li, Shunhui Wei, Kenneth Cheng, Natalia V Gounko, Russell E Ericksen, Aimin Xu, Wanjin Hong, Weiping Han

EMBO Rep. 2014 Jun; 15(6): 714–722. Published online 2014 Apr 7. doi: 10.1002/embr.201338181

PMCID:: PMC4197882

Abstract Article PDF–1.3M

Select item 405988917.

MOF-associated complexes ensure stem cell identity and Xist repression

Tomasz Chelmicki, Friederike Dündar, Matthew James Turley, Tasneem Khanam, Tugce Aktas, Fidel Ramírez, Anne-Valerie Gendrel, Patrick Rudolf Wright, Pavankumar Videm, Rolf Backofen, Edith Heard, Thomas Manke, Asifa Akhtar

eLife. 2014; 3: e02024. Published online 2014 May 19. doi: 10.7554/eLife.02024

PMCID:: PMC4059889

Abstract Article PDF–9.7M

Select item 392167418.

Essential role of lncRNA binding for WDR5 maintenance of active chromatin and embryonic stem cell pluripotency

Yul W Yang, Ryan A Flynn, Yong Chen, Kun Qu, Bingbing Wan, Kevin C Wang, Ming Lei, Howard Y Chang

eLife. 2014; 3: e02046. Published online 2014 Feb 12. doi: 10.7554/eLife.02046

PMCID:: PMC3921674

Abstract Article PDF–3.2M

Select item 378453919.

Glucagon regulates gluconeogenesis through KAT2B- and WDR5-mediated epigenetic effects

Kim Ravnskjaer, Meghan F. Hogan, Denise Lackey, Laszlo Tora, Sharon Y.R. Dent, Jerrold Olefsky, Marc Montminy

J Clin Invest. 2013 Oct 1; 123(10): 4318–4328. Published online 2013 Sep 24. doi: 10.1172/JCI69035

PMCID:: PMC3784539

Abstract Article PDF–1.9M

Select item 374205220.

Jmjd3 Negatively Regulates Reprogramming Through Histone Demethylase Activity- Dependent and -Independent Pathways

Wei Zhao, Qingtian Li, Stephen Ayers, Yifeng Gu, Zhong Shi, Yidong Chen, Helen Y. Wang, Rong-Fu Wang

Cell. Author manuscript; available in PMC 2014 Feb 28.

Published in final edited form as: Cell. 2013 Feb 28; 152(5): 1037–1050. doi: 10.1016/j.cell.2013.02.006

PMCID:: PMC3742052

Abstract Article PDF–3.2M

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