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Select item 112135041.

White adipocytes in subcutaneous fat depots require KLF15 for maintenance in preclinical models

Liang Li, Brian J. Feldman

J Clin Invest. 2024 Jul 1; 134(13): e172360. Published online 2024 Jul 1. doi: 10.1172/JCI172360

PMCID:: PMC11213504

Abstract Article PDF–5.2M

Select item 110612302.

KLF15 maintains contractile phenotype of vascular smooth muscle cells and prevents thoracic aortic dissection by interacting with MRTFB

Guangming Fang, Yexuan Tian, Shan Huang, Xiaoping Zhang, Yan Liu, Yulin Li, Jie Du, Shijuan Gao

J Biol Chem. 2024 May; 300(5): 107260. Published online 2024 Apr 4. doi: 10.1016/j.jbc.2024.107260

PMCID:: PMC11061230

Abstract Article PDF–4.9M

Select item 106228423.

The transcriptional regulator KLF15 is necessary for myoblast differentiation and muscle regeneration by activating FKBP5

Shijuan Gao, Shan Huang, Yanhong Zhang, Guangming Fang, Yan Liu, Congcong Zhang, Yulin Li, Jie Du

J Biol Chem. 2023 Oct; 299(10): 105226. Published online 2023 Sep 4. doi: 10.1016/j.jbc.2023.105226

PMCID:: PMC10622842

Abstract Article PDF–5.7M

Select item 105724684.

Krüppel-like Factor 15 Suppresses Ferroptosis by Activating an NRF2/GPX4 Signal to Protect against Folic Acid-Induced Acute Kidney Injury

Xue Yang, Shihui Dong, Yun Fan, Yuanyuan Xia, Fan Yang, Zhaohong Chen, Dacheng Chen, Mingchao Zhang, Dandan Liang, Caihong Zeng

Int J Mol Sci. 2023 Oct; 24(19): 14530. Published online 2023 Sep 26. doi: 10.3390/ijms241914530

PMCID:: PMC10572468

Abstract Article PDF–8.0M

Select item 100337035.

A defect in mitochondrial protein translation influences mitonuclear communication in the heart

Feng Gao, Tian Liang, Yao Wei Lu, Xuyang Fu, Xiaoxuan Dong, Linbin Pu, Tingting Hong, Yuxia Zhou, Yu Zhang, Ning Liu, Feng Zhang, Jianming Liu, Andrea P. Malizia, Hong Yu, Wei Zhu, Douglas B. Cowan, Hong Chen, Xinyang Hu, John D. Mably, Jian’an Wang, Da-Zhi Wang, Jinghai Chen

Nat Commun. 2023; 14: 1595. Published online 2023 Mar 22. doi: 10.1038/s41467-023-37291-5

PMCID:: PMC10033703

Abstract Article PDF–10M

Select item 95937306.

KLF15 controls brown adipose tissue transcriptional flexibility and metabolism in response to various energetic demands

Liyan Fan, Alexander F. Lesser, David R. Sweet, Komal S. Keerthy, Yuan Lu, Ernest R. Chan, Vinesh Vinayachandran, Olga Ilkayeva, Tapatee Das, Christopher B. Newgard, Mukesh K. Jain

iScience. 2022 Nov 18; 25(11): 105292. Published online 2022 Oct 8. doi: 10.1016/j.isci.2022.105292

PMCID:: PMC9593730

Abstract Article PDF–2.3M

Select item 91900047.

Transcription factors KLF15 and PPARδ cooperatively orchestrate genome-wide regulation of lipid metabolism in skeletal muscle

Liyan Fan, David R. Sweet, Erica K. Fan, Domenick A. Prosdocimo, Annmarie Madera, Zhen Jiang, Roshan Padmanabhan, Saptarsi M. Haldar, Vinesh Vinayachandran, Mukesh K. Jain

J Biol Chem. 2022 Jun; 298(6): 101926. Published online 2022 Apr 9. doi: 10.1016/j.jbc.2022.101926

PMCID:: PMC9190004

Abstract Article PDF–1.9M

Select item 91856818.

CTRP12 alleviates cardiomyocyte ischemia-reperfusion injury via regulation of KLF15

Bo Liao, Xiaoyuan Tian

Mol Med Rep. 2022 Jul; 26(1): 247. Published online 2022 Jun 2. doi: 10.3892/mmr.2022.12763

PMCID:: PMC9185681

Abstract Article PDF–1.6M

Select item 91596769.

A Piezo1/KLF15/IL-6 axis mediates immobilization-induced muscle atrophy

Yu Hirata, Kazuhiro Nomura, Daisuke Kato, Yoshihisa Tachibana, Takahiro Niikura, Kana Uchiyama, Tetsuya Hosooka, Tomoaki Fukui, Keisuke Oe, Ryosuke Kuroda, Yuji Hara, Takahiro Adachi, Koji Shibasaki, Hiroaki Wake, Wataru Ogawa

J Clin Invest. 2022 May 16; 132(10): e154611. Published online 2022 May 16. doi: 10.1172/JCI154611

PMCID:: PMC9159676

Abstract Article PDF–12M

Select item 875043810.

KLF15 overexpression in myocytes fails to ameliorate ALS-related pathology or extend the lifespan of SOD1G93A mice

Ryan Massopust, Devin Juros, Dillon Shapiro, Mikayla Lopes, Saptarsi M. Haldar, Thomas Taetzsch, Gregorio Valdez

Neurobiol Dis. Author manuscript; available in PMC 2023 Jan 1.

Published in final edited form as: Neurobiol Dis. 2022 Jan; 162: 105583. Published online 2021 Dec 11. doi: 10.1016/j.nbd.2021.105583

PMCID:: PMC8750438

Abstract Article PDF–2.8M

Select item 847502911.

Krüppel‐Like Factor 15/Interleukin 11 Axis‐Mediated Adventitial Remodeling Depends on Extracellular Signal‐Regulated Kinases 1 and 2 Activation in Angiotensin II–Induced Hypertension

Yue‐Tong Guo, Yuan‐Yuan Lu, Xiao Lu, Shun He, Shi‐Jin Li, Shuai Shao, Han‐Dan Zhou, Rui‐Qi Wang, Xiao‐Dong Li, Ping‐Jin Gao

J Am Heart Assoc. 2021 Aug 17; 10(16): e020554. Published online 2021 Aug 5. doi: 10.1161/JAHA.120.020554

PMCID:: PMC8475029

Abstract Article PDF–3.1M

Select item 844874912.

Kruppel-like factor 15 induces the development of mature hepatocyte-like cells from hepatoblasts

Kazuya Anzai, Kota Tsuruya, Kinuyo Ida, Tatehiro Kagawa, Yutaka Inagaki, Akihide Kamiya

Sci Rep. 2021; 11: 18551. Published online 2021 Sep 17. doi: 10.1038/s41598-021-97937-6

PMCID:: PMC8448749

Abstract Article PDF–5.0M

Select item 831323913.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 809393914.

Gluconeogenic signals regulate hepcidin gene expression via a CRBN-KLF15 axis

Jeong-Rang Jo, Sung-Eun Lee, Seungwon An, Balachandar Nedumaran, Swati Ghosh, Keun-Gyu Park, Yong Deuk Kim

BMB Rep. 2021 Apr 30; 54(4): 221–226. Published online 2021 Apr 30. doi: 10.5483/BMBRep.2021.54.4.215

PMCID:: PMC8093939

Abstract Article PDF–778K

Select item 793877015.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 788031116.

Muscle Krüppel-like factor 15 regulates lipid flux and systemic metabolic homeostasis

Liyan Fan, David R. Sweet, Domenick A. Prosdocimo, Vinesh Vinayachandran, Ernest R. Chan, Rongli Zhang, Olga Ilkayeva, Yuan Lu, Komal S. Keerthy, Chloe E. Booth, Christopher B. Newgard, Mukesh K. Jain

J Clin Invest. 2021 Feb 15; 131(4): e139496. Published online 2021 Feb 15. doi: 10.1172/JCI139496

PMCID:: PMC7880311

Abstract Article PDF–4.5M

Select item 767415217.

Muscle overexpression of Klf15 via an AAV8-Spc5-12 construct does not provide benefits in spinal muscular atrophy mice

Nina Ahlskog, Daniel Hayler, Anja Krueger, Sabrina Kubinski, Peter Claus, Suzan M. Hammond, Matthew J. A. Wood, Rafael J. Yáñez-Muñoz, Melissa Bowerman

Gene Ther. 2020; 27(10): 505–515. Published online 2020 Apr 20. doi: 10.1038/s41434-020-0146-8

PMCID:: PMC7674152

Abstract Article PDF–1.0M

Select item 767350018.

In silico analysis identifies a putative cell-of-origin for BRAF fusion-positive cerebellar pilocytic astrocytoma

Subhi Talal Younes, Betty Herrington

PLoS One. 2020; 15(11): e0242521. Published online 2020 Nov 18. doi: 10.1371/journal.pone.0242521

PMCID:: PMC7673500

Abstract Article PDF–2.8M

Select item 760831119.

Variants of innate CD8⁺ T cells are associated with Grip2 and Klf15 genes

Yuna Jo, Lois Balmer, Byunghyuk Lee, Ju A Shim, Laraib Amir Ali, Grant Morahan, Changwan Hong

Cell Mol Immunol. 2020 Sep; 17(9): 1007–1009. Published online 2020 Jan 9. doi: 10.1038/s41423-019-0357-3

PMCID:: PMC7608311

Article PDF–668K

Select item 719744120.

KLF15 Regulates the Circadian Susceptibility to Ischemia Reperfusion Injury in the Heart

Le Li, Hui Li, Chih-Liang Tien, Mukesh K. Jain, Lilei Zhang

Circulation. Author manuscript; available in PMC 2021 Apr 28.

Published in final edited form as: Circulation. 2020 Apr 28; 141(17): 1427–1429. Published online 2020 Apr 27. doi: 10.1161/CIRCULATIONAHA.119.041664

PMCID:: PMC7197441

Article PDF–417K

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