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Select item 105658761.

Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates

Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert

Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644

PMCID:: PMC10565876

Abstract Article PDF–3.7M

Select item 102374222.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 101122813.

TNIP1 inhibits selective autophagy via bipartite interaction with LC3/GABARAP and TAX1BP1

François Le Guerroué, Eric N Bunker, William M Rosencrans, Jack T Nguyen, Mohammed A Basar, Achim Werner, Tsui-Fen Chou, Chunxin Wang, Richard J Youle

Mol Cell. Author manuscript; available in PMC 2024 Mar 16.

Published in final edited form as: Mol Cell. 2023 Mar 16; 83(6): 927–941.e8. Published online 2023 Mar 9. doi: 10.1016/j.molcel.2023.02.023

PMCID:: PMC10112281

Abstract Article PDF–2.4M

Select item 101036784.

Specific pupylation as IDEntity reporter (SPIDER) for the identification of protein-biomolecule interactions

He-Wei Jiang, Hong Chen, Yun-Xiao Zheng, Xue-Ning Wang, Qingfeng Meng, Jin Xie, Jiong Zhang, ChangSheng Zhang, Zhao-Wei Xu, Zi-Qing Chen, Lei Wang, Wei-Sha Kong, Kuan Zhou, Ming-Liang Ma, Hai-Nan Zhang, Shu-Juan Guo, Jun-Biao Xue, Jing-Li Hou, Zhe-Yi Liu, Wen-Xue Niu, Fang-Jun Wang, Tao Wang, Wei Li, Rui-Na Wang, Yong-Jun Dang, Daniel M. Czajkowsky, JianFeng Pei, Jia-Jia Dong, Sheng-Ce Tao

Sci China Life Sci. 2023 Apr 14 : 1–19. doi: 10.1007/s11427-023-2316-2 [Epub ahead of print]

PMCID:: PMC10103678

Abstract Article PDF–2.4M

Select item 100395115.

Study of FOXO1-interacting proteins using TurboID-based proximity labeling technology

Yanting Su, Yuanyuan Guo, Jieyu Guo, Ting Zeng, Ting Wang, Wu Liu

BMC Genomics. 2023; 24: 146. Published online 2023 Mar 24. doi: 10.1186/s12864-023-09238-z

PMCID:: PMC10039511

Abstract Article PDF–2.0M

Select item 96044356.

Binding of Glycerol to Human Galectin-7 Expands Stability and Modulates Its Functions

Yebing Liang, Yuxiang Wang, Xingyu Zhu, Jun Cai, Anqi Shi, Jing Huang, Qiuju Zhu, Yunlong Si

Int J Mol Sci. 2022 Oct; 23(20): 12318. Published online 2022 Oct 14. doi: 10.3390/ijms232012318

PMCID:: PMC9604435

Abstract Article PDF–2.6M

Select item 92778537.

A functional reference map of the RNF8 interactome in cancer

Chuanyang Liu, Jingyu Kuang, Yuxuan Wang, Ting Duan, Lu Min, Chenyu Lu, Tianyi Zhang, Ruifen Chen, Ying Wu, Lingyun Zhu

Biol Direct. 2022; 17: 17. Published online 2022 Jul 13. doi: 10.1186/s13062-022-00331-z

PMCID:: PMC9277853

Abstract Article PDF–5.9M

Select item 89566048.

CRISPR activation screen identifies BCL-2 proteins and B3GNT2 as drivers of cancer resistance to T cell-mediated cytotoxicity

Julia Joung, Paul C. Kirchgatterer, Ankita Singh, Jang H. Cho, Suchita P. Nety, Rebecca C. Larson, Rhiannon K. Macrae, Rebecca Deasy, Yuen-Yi Tseng, Marcela V. Maus, Feng Zhang

Nat Commun. 2022; 13: 1606. Published online 2022 Mar 25. doi: 10.1038/s41467-022-29205-8

PMCID:: PMC8956604

Abstract Article PDF–3.9M

Select item 89336999.

Turnover of the mTOR inhibitor, DEPTOR, and downstream AKT phosphorylation in multiple myeloma cells, is dependent on ERK1-mediated phosphorylation

Mario Vega, Yu Chen, Yijiang Shi, Joseph Gera, Alan Lichtenstein

J Biol Chem. 2022 Apr; 298(4): 101750. Published online 2022 Feb 23. doi: 10.1016/j.jbc.2022.101750

PMCID:: PMC8933699

Abstract Article PDF–1.6M

Select item 860245110.

Identification of proximal SUMO-dependent interactors using SUMO-ID

Orhi Barroso-Gomila, Fredrik Trulsson, Veronica Muratore, Iñigo Canosa, Laura Merino-Cacho, Ana Rosa Cortazar, Coralia Pérez, Mikel Azkargorta, Ibon Iloro, Arkaitz Carracedo, Ana M. Aransay, Felix Elortza, Ugo Mayor, Alfred C. O. Vertegaal, Rosa Barrio, James D. Sutherland

Nat Commun. 2021; 12: 6671. Published online 2021 Nov 18. doi: 10.1038/s41467-021-26807-6

PMCID:: PMC8602451

Abstract Article PDF–11M

Select item 859287311.

Perturbing dimer interactions and allosteric communication modulates the immunosuppressive activity of human galectin-7

N. T. Hang Pham, Myriam Létourneau, Marlène Fortier, Gabriel Bégin, M. Sameer Al-Abdul-Wahid, Fabrizio Pucci, Benjamin Folch, Marianne Rooman, David Chatenet, Yves St-Pierre, Patrick Lagüe, Charles Calmettes, Nicolas Doucet

J Biol Chem. 2021 Nov; 297(5): 101308. Published online 2021 Oct 19. doi: 10.1016/j.jbc.2021.101308

PMCID:: PMC8592873

Abstract Article PDF–1.9M

Select item 846050912.

Imitating evolution’s tinkering by protein engineering reveals extension of human galectin-7 activity

Anna-Kristin Ludwig, Malwina Michalak, Adele Gabba, Tanja J. Kutzner, Donella M. Beckwith, Forrest G. FitzGerald, Gabriel García Caballero, Joachim C. Manning, Mark Kriegsmann, Herbert Kaltner, Paul V. Murphy, Maré Cudic, Jürgen Kopitz, Hans-Joachim Gabius

Histochem Cell Biol. 2021; 156(3): 253–272. Published online 2021 Jun 21. doi: 10.1007/s00418-021-02004-w

PMCID:: PMC8460509

Abstract Article PDF–4.5M

Select item 823185413.

Towards a Better Understanding of the Relationships between Galectin-7, p53 and MMP-9 during Cancer Progression

Yves St-Pierre

Biomolecules. 2021 Jun; 11(6): 879. Published online 2021 Jun 14. doi: 10.3390/biom11060879

PMCID:: PMC8231854

Abstract Article PDF–1.2M

Select item 816503014.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 807101215.

Degraded Arabinogalactans and Their Binding Properties to Cancer-Associated Human Galectins

Lukas Pfeifer, Alexander Baumann, Lea Madlen Petersen, Bastian Höger, Eric Beitz, Birgit Classen

Int J Mol Sci. 2021 Apr; 22(8): 4058. Published online 2021 Apr 14. doi: 10.3390/ijms22084058

PMCID:: PMC8071012

Abstract Article PDF–2.8M

Select item 796286016.

Proteomic analysis shows that the main constituent of subepidermal localized cutaneous amyloidosis is not galectin-7.

Jessica R Chapman, Anna Liu, San S Yi, Enmily Hernandez, Maria Stella Ritorto, Achim A Jungbluth, Melissa Pulitzer, Ahmet Dogan

Amyloid. Author manuscript; available in PMC 2022 Mar 1.

Published in final edited form as: Amyloid. 2021 Mar; 28(1): 35–41. Published online 2020 Sep 1. doi: 10.1080/13506129.2020.1811962

PMCID:: PMC7962860

Abstract Article PDF–1.0M

Select item 792741517.

FBW7 suppresses ovarian cancer development by targeting the N⁶-methyladenosine binding protein YTHDF2

Fei Xu, Jiajia Li, Mengdong Ni, Jingyi Cheng, Haiyun Zhao, Shanshan Wang, Xiang Zhou, Xiaohua Wu

Mol Cancer. 2021; 20: 45. Published online 2021 Mar 3. doi: 10.1186/s12943-021-01340-8

PMCID:: PMC7927415

Abstract Article PDF–2.9M

Select item 789431818.

Structural Characterization of N‐Linked Glycans in the Receptor Binding Domain of the SARS‐CoV‐2 Spike Protein and their Interactions with Human Lectins

Maria Pia Lenza, Iker Oyenarte, Dr. Tammo Diercks, Jon Imanol Quintana, Dr. Ana Gimeno, Dr. Helena Coelho, Ana Diniz, Dr. Francesca Peccati, Sandra Delgado, Alexandre Bosch, Dr. Mikel Valle, Dr. Oscar Millet, Prof. Dr. Nicola G. A. Abrescia, Dr. Asís Palazón, Dr. Filipa Marcelo, Dr. Gonzalo Jiménez‐Osés, Prof. Dr. Jesús Jiménez‐Barbero, Dr. Ana Ardá, Dr. June Ereño‐Orbea

Angew Chem Int Ed Engl. 2020 Dec 21; 59(52): 23763–23771. Published online 2020 Oct 22. doi: 10.1002/anie.202011015

PMCID:: PMC7894318

Abstract Article PDF–2.3M

Select item 777337619.

Galectin-7 downregulation in lesional keratinocytes contributes to enhanced IL-17A signaling and skin pathology in psoriasis

Hung-Lin Chen, Chia-Hui Lo, Chi-Chun Huang, Meng-Ping Lu, Po-Yuan Hu, Chang-Shan Chen, Di-Yen Chueh, Peilin Chen, Teng-Nan Lin, Yuan-Hsin Lo, Yu-Ping Hsiao, Daniel K. Hsu, Fu-Tong Liu

J Clin Invest. 2021 Jan 4; 131(1): e130740. Published online 2021 Jan 4. doi: 10.1172/JCI130740

PMCID:: PMC7773376

Abstract Article PDF–9.0M

Select item 775805020.

In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators

Jennifer L. Franks, Raquel C. Martinez-Chacin, Xianxi Wang, Rochelle L. Tiedemann, Thomas Bonacci, Rajarshi Choudhury, Derek L. Bolhuis, Taylor P. Enrico, Ryan D. Mouery, Jeffrey S. Damrauer, Feng Yan, Joseph S. Harrison, M. Ben Major, Katherine A. Hoadley, Aussie Suzuki, Scott B. Rothbart, Nicholas G. Brown, Michael J. Emanuele

PLoS Biol. 2020 Dec; 18(12): e3000975. Published online 2020 Dec 11. doi: 10.1371/journal.pbio.3000975

PMCID:: PMC7758050

Abstract Article PDF–4.2M

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