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Select item 108959011.

RGS6 drives cardiomyocyte death following nucleolar stress by suppressing Nucleolin/miRNA-21

Abhishek Singh Sengar, Manish Kumar, Chetna Rai, Sreemoyee Chakraborti, Dinesh Kumar, Pranesh Kumar, Sukhes Mukherjee, Kausik Mondal, Adele Stewart, Biswanath Maity

J Transl Med. 2024; 22: 204. Published online 2024 Feb 26. doi: 10.1186/s12967-024-04985-3

PMCID:: PMC10895901

Abstract Article PDF–5.3M

Select item 107649582.

TRIM28-mediated nucleocapsid protein SUMOylation enhances SARS-CoV-2 virulence

Jiang Ren, Shuai Wang, Zhi Zong, Ting Pan, Sijia Liu, Wei Mao, Huizhe Huang, Xiaohua Yan, Bing Yang, Xin He, Fangfang Zhou, Long Zhang

Nat Commun. 2024; 15: 244. Published online 2024 Jan 4. doi: 10.1038/s41467-023-44502-6

PMCID:: PMC10764958

Abstract Article PDF–4.4M

Select item 107440443.

Structural Integrity of Nucleolin Is Required to Suppress TDP-43-Mediated Cytotoxicity in Yeast and Human Cell Models

Caterina Peggion, Maria Lina Massimino, Daniel Pereira, Sara Granuzzo, Francesca Righetto, Raissa Bortolotto, Jessica Agostini, Geppo Sartori, Alessandro Bertoli, Raffaele Lopreiato

Int J Mol Sci. 2023 Dec; 24(24): 17466. Published online 2023 Dec 14. doi: 10.3390/ijms242417466

PMCID:: PMC10744044

Abstract Article PDF–2.5M

Select item 106176734.

The midnolin-proteasome pathway catches proteins for ubiquitination-independent degradation

Xin Gu, Christopher Nardone, Nolan Kamitaki, Aoyue Mao, Stephen J. Elledge, Michael E. Greenberg

Science. Author manuscript; available in PMC 2023 Oct 31.

Published in final edited form as: Science. 2023 Aug 25; 381(6660): eadh5021. Published online 2023 Aug 25. doi: 10.1126/science.adh5021

PMCID:: PMC10617673

Abstract Article PDF–3.6M

Select item 102841175.

Exploring an Alternative Cysteine-Reactive Chemistry to Enable Proteome-Wide PPI Analysis by Cross-Linking Mass Spectrometry

Fenglong Jiao, Leah J. Salituro, Clinton Yu, Craig B. Gutierrez, Scott D. Rychnovsky, Lan Huang

Anal Chem. Author manuscript; available in PMC 2023 Jun 21.

Published in final edited form as: Anal Chem. 2023 Jan 31; 95(4): 2532–2539. Published online 2023 Jan 18. doi: 10.1021/acs.analchem.2c04986

PMCID:: PMC10284117

Abstract Article PDF–2.5M

Select item 102374226.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 101645647.

The ubiquitin-specific protease USP36 SUMOylates EXOSC10 and promotes the nucleolar RNA exosome function in rRNA processing

Yingxiao Chen, Yanping Li, Roselyn S Dai, Jonathan C Savage, Ujwal Shinde, John Klimek, Larry L David, Emma A Young, Markus Hafner, Rosalie C Sears, Xiao-Xin Sun, Mu-Shui Dai

Nucleic Acids Res. 2023 May 8; 51(8): 3934–3949. Published online 2023 Mar 13. doi: 10.1093/nar/gkad140

PMCID:: PMC10164564

Abstract Article PDF–3.8M

Select item 101516158.

Cross-linking mass spectrometry discovers, evaluates, and corroborates structures and protein–protein interactions in the human cell

Tara K. Bartolec, Xabier Vázquez-Campos, Alexander Norman, Clement Luong, Marcus Johnson, Richard J. Payne, Marc R. Wilkins, Joel P. Mackay, Jason K. K. Low

Proc Natl Acad Sci U S A. 2023 Apr 25; 120(17): e2219418120. Published online 2023 Apr 18. doi: 10.1073/pnas.2219418120

PMCID:: PMC10151615

Abstract Article PDF–2.9M

Select item 100644919.

CRYβB2 enhances tumorigenesis through upregulation of nucleolin in triple negative breast cancer

Yu Yan, Athira Narayan, Soonweng Cho, Zhiqiang Cheng, Jun O. Liu, Heng Zhu, Guannan Wang, Bryan Wharram, Ala Lisok, Mary Brummet, Harumi Saeki, Tao Huang, Kathleen Gabrielson, Edward Gabrielson, Leslie Cope, Yasmine M. Kanaan, Ali Afsari, Tammey Naab, Harris G. Yfantis, Stefan Ambs, Martin G. Pomper, Saraswati Sukumar, Vanessa F. Merino

Oncogene. Author manuscript; available in PMC 2023 Mar 31.

Published in final edited form as: Oncogene. 2021 Sep; 40(38): 5752–5763. Published online 2021 Aug 2. doi: 10.1038/s41388-021-01975-3

PMCID:: PMC10064491

Abstract Article PDF–2.5M

Select item 1000589810.

The p97/VCP segregase is essential for arsenic-induced degradation of PML and PML-RARA

Ellis G. Jaffray, Michael H. Tatham, Barbara Mojsa, Magda Liczmanska, Alejandro Rojas-Fernandez, Yili Yin, Graeme Ball, Ronald T. Hay

J Cell Biol. 2023 Apr 3; 222(4): e202201027. Published online 2023 Feb 28. doi: 10.1083/jcb.202201027

PMCID:: PMC10005898

Abstract Article PDF–6.7M

Select item 997863511.

Fibril treatment changes protein interactions of tau and α-synuclein in human neurons

Tagan A. Griffin, Paul D. Schnier, Elisa M. Cleveland, Robert W. Newberry, Julia Becker, George A. Carlson

J Biol Chem. 2023 Mar; 299(3): 102888. Published online 2023 Jan 10. doi: 10.1016/j.jbc.2023.102888

PMCID:: PMC9978635

Abstract Article PDF–10M

Select item 995044712.

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma

Yu-Fei Cao, Lei Xie, Bei-Bei Tong, Man-Yu Chu, Wen-Qi Shi, Xiang Li, Jian-Zhong He, Shao-Hong Wang, Zhi-Yong Wu, Dan-Xia Deng, Ya-Qi Zheng, Zhi-Mao Li, Xiu-E Xu, Lian-Di Liao, Yin-Wei Cheng, Li-Yan Li, Li-Yan Xu, En-Min Li

Cell Death Differ. 2023 Feb; 30(2): 527–543. Published online 2022 Dec 16. doi: 10.1038/s41418-022-01104-x

PMCID:: PMC9950447

Abstract Article PDF–8.4M

Select item 989685913.

Nucleolin mediates SARS-CoV-2 replication and viral-induced apoptosis of host cells

Vanessa F. Merino, Yu Yan, Alvaro A. Ordonez, C. Korin Bullen, Albert Lee, Harumi Saeki, Krishanu Ray, Tao Huang, Sanjay K. Jain, Martin G. Pomper

Antiviral Res. 2023 Mar; 211: 105550. Published online 2023 Feb 3. doi: 10.1016/j.antiviral.2023.105550

PMCID:: PMC9896859

Abstract Article PDF–12M

Select item 980161014.

USP13 regulates HMGB1 stability and secretion through its deubiquitinase activity

Jaemin Shin, Young Hun Kim, Bin Lee, Jae Ho Chang, Hee Youn Choi, Hoojung Lee, Ki Chan Song, Man Sup Kwak, Ji Eun Choi, Jeon-Soo Shin

Mol Med. 2022; 28: 164. Published online 2022 Dec 30. doi: 10.1186/s10020-022-00596-0

PMCID:: PMC9801610

Abstract Article PDF–2.9M

Select item 979798815.

TBK1 posphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1

Jianwen Zhou, Nikoline Lander Rasmussen, Hallvard Lauritz Olsvik, Vyacheslav Akimov, Zehan Hu, Gry Evjen, Stéphanie Kaeser-Pebernard, Devanarayanan Siva Sankar, Carole Roubaty, Pauline Verlhac, Nicole van de Beek, Fulvio Reggiori, Yakubu Princely Abudu, Blagoy Blagoev, Trond Lamark, Terje Johansen, Jörn Dengjel

J Cell Biol. 2023 Feb 6; 222(2): e202108144. Published online 2022 Dec 27. doi: 10.1083/jcb.202108144

PMCID:: PMC9797988

Abstract Article PDF–6.9M

Select item 979580716.

Mapping of functional SARS-CoV-2 receptors in human lungs establishes differences in variant binding and SLC1A5 as a viral entry modulator of hACE2

Annarita Miluzio, Alessandro Cuomo, Chiara Cordiglieri, Lorena Donnici, Elisa Pesce, Mauro Bombaci, Matteo Conti, Alessandra Fasciani, Luigi Terracciano, Lara Manganaro, Mirco Toccafondi, Alessandra Scagliola, Stefania Oliveto, Sara Ricciardi, Renata Grifantini, Raffaele De Francesco, Sergio Abrignani, Nicola Manfrini, Stefano Biffo

eBioMedicine. 2023 Jan; 87: 104390. Published online 2022 Dec 28. doi: 10.1016/j.ebiom.2022.104390