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Select item 111219141.

The Long Non-Coding RNA MALAT1 Modulates NR4A1 Expression through a Downstream Regulatory Element in Specific Cancer Cell Types

Sara Wernig-Zorc, Uwe Schwartz, Paulina Martínez-Rodríguez, Josefa Inalef, Francisca Pavicic, Pamela Ehrenfeld, Gernot Längst, Rodrigo Maldonado

Int J Mol Sci. 2024 May; 25(10): 5515. Published online 2024 May 18. doi: 10.3390/ijms25105515

PMCID:: PMC11121914

Abstract Article PDF–4.9M

Select item 110954312.

Progressive reduction of nuclear receptor Nr4a1 mediates age‐dependent cognitive decline

Jiang Chen, Zhi Zhang, Ying Liu, Lili Huang, Yi Liu, Dan Yang, Xinyu Bao, Pinyi Liu, Yuhan Ge, Qingqing Li, Xin Shu, Lushan Xu, Yun Stone Shi, Xiaolei Zhu, Yun Xu

Alzheimers Dement. 2024 May; 20(5): 3504–3524. Published online 2024 Apr 11. doi: 10.1002/alz.13819

PMCID:: PMC11095431

Abstract Article PDF–11M

Select item 109131213.

SOCS3, Transcriptionally Activated by NR4A1, Induces Apoptosis and Extracellular Matrix Degradation of Vaginal Fibroblasts in Pelvic Organ Prolapse

Xin Jin, Qing Hu, Meiying Qin, Yitong Yin, Zhijun Xia

Balkan Med J. 2024 Mar; 41(2): 105–112. Published online 2024 Mar 1. doi: 10.4274/balkanmedj.galenos.2023.2023-10-60

PMCID:: PMC10913121

Abstract Article PDF–2.3M

Select item 108379984.

Hyperinsulinemia impairs decidualization via AKT-NR4A1 signaling: new insight into polycystic ovary syndrome (PCOS)-related infertility

Nan-Xing Jiang, Wei-Jie Zhao, Hao-Ran Shen, Dan-feng Du, Xue-Lian Li

J Ovarian Res. 2024; 17: 31. Published online 2024 Feb 3. doi: 10.1186/s13048-023-01334-8

PMCID:: PMC10837998

Abstract Article PDF–9.9M

Select item 106176735.

The midnolin-proteasome pathway catches proteins for ubiquitination-independent degradation

Xin Gu, Christopher Nardone, Nolan Kamitaki, Aoyue Mao, Stephen J. Elledge, Michael E. Greenberg

Science. Author manuscript; available in PMC 2023 Oct 31.

Published in final edited form as: Science. 2023 Aug 25; 381(6660): eadh5021. Published online 2023 Aug 25. doi: 10.1126/science.adh5021

PMCID:: PMC10617673

Abstract Article PDF–3.6M

Select item 104354236.

ERK5 Cooperates With MEF2C to Regulate Nr4a1 Transcription in MA-10 and MLTC-1 Leydig Cells

Karine de Mattos, Félix-Olivier Dumas, Gabriel Henrique Campolina-Silva, Clémence Belleannée, Robert S Viger, Jacques J Tremblay

Endocrinology. 2023 Sep; 164(9): bqad120. Published online 2023 Aug 4. doi: 10.1210/endocr/bqad120

PMCID:: PMC10435423

Abstract Article

Select item 102577807.

Apoptosis of pro-B lymphocytes induced by NR4A1 activation in the presence of gingival fibroblast exosomes and TNFα, caspase 8, STAT3, and Akt pathways modulators

Carmen Amititeloaie, Liliana Chelaru, Gabriela Luminiţa Geleţu, Anca Sava, Alexandra Jităreanu, Andreea Mihaela Tibeică, Marcel Costuleanu

Rom J Morphol Embryol. 2023 Jan-Mar; 64(1): 35–40. Published online 2023 Mar 31. doi: 10.47162/RJME.64.1.04

PMCID:: PMC10257780

Abstract Article PDF–770K

Select item 101794758.

Flavone and Hydroxyflavones Are Ligands That Bind the Orphan Nuclear Receptor 4A1 (NR4A1)

Miok Lee, Srijana Upadhyay, Fuada Mariyam, Greg Martin, Amanuel Hailemariam, Kyongbum Lee, Arul Jayaraman, Robert S. Chapkin, Syng-Ook Lee, Stephen Safe

Int J Mol Sci. 2023 May; 24(9): 8152. Published online 2023 May 2. doi: 10.3390/ijms24098152

PMCID:: PMC10179475

Abstract Article PDF–4.0M

Select item 101694529.

Nr4a1 promotes renal interstitial fibrosis by regulating the p38 MAPK phosphorylation

Yilin Tao, Chengyuan Tang, Ju Wei, Yi Shan, Xi Fang, Ying Li

Mol Med. 2023; 29: 63. Published online 2023 May 9. doi: 10.1186/s10020-023-00657-y

PMCID:: PMC10169452

Abstract Article PDF–2.3M

Select item 1010805410.

Nuclear Receptor Subfamily 4A Signaling as a Key Disease Pathway of CD1c+ Dendritic Cell Dysregulation in Systemic Sclerosis

Nila H. Servaas, Sanne Hiddingh, Eleni Chouri, Catharina G. K. Wichers, Alsya J. Affandi, Andrea Ottria, Cornelis P. J. Bekker, Marta Cossu, Sandra C. Silva‐Cardoso, Maarten van der Kroef, Anneline C. Hinrichs, Tiago Carvalheiro, Nadia Vazirpanah, Lorenzo Beretta, Marzia Rossato, Femke Bonte‐Mineur, Timothy R. D. J. Radstake, Jonas J. W. Kuiper, Marianne Boes, Aridaman Pandit

Arthritis Rheumatol. 2023 Feb; 75(2): 279–292. Published online 2022 Dec 8. doi: 10.1002/art.42319

PMCID:: PMC10108054

Abstract Article PDF–3.0M

Select item 992166711.

Nur77 Serves as a Potential Prognostic Biomarker That Correlates with Immune Infiltration and May Act as a Good Target for Prostate adenocarcinoma

Qiong-Ying Hu, Jie Liu, Xiao-Kun Zhang, Wan-Ting Yang, Yu-Tian Tao, Ce Chen, Ye-He Qian, Jin-Shan Tang, Xin-Sheng Yao, Ying-He Xu, Jing-Hui Wang

Molecules. 2023 Feb; 28(3): 1238. Published online 2023 Jan 28. doi: 10.3390/molecules28031238

PMCID:: PMC9921667

Abstract Article PDF–58M

Select item 991930412.

Identification of a Novel Angiogenesis Signalling circSCRG1/miR-1268b/NR4A1 Pathway in Atherosclerosis and the Regulatory Effects of TMP-PF In Vitro

Rong Yuan, Qiqi Xin, Xiaochang Ma, Meng Yu, Yu Miao, Keji Chen, Weihong Cong

Molecules. 2023 Feb; 28(3): 1271. Published online 2023 Jan 28. doi: 10.3390/molecules28031271

PMCID:: PMC9919304

Abstract Article PDF–21M

Select item 984122913.

Mst1-mediated phosphorylation of Nur77 improves the endometrial receptivity in human and mice

Xinyu Cai, Yue Jiang, Zhiwen Cao, Mei Zhang, Na Kong, Lina Yu, Yedong Tang, Shuangbo Kong, Wenbo Deng, Haibin Wang, Jianxin Sun, Lijun Ding, Ruiwei Jiang, Haixiang Sun, Guijun Yan

eBioMedicine. 2023 Feb; 88: 104433. Published online 2023 Jan 7. doi: 10.1016/j.ebiom.2022.104433

PMCID:: PMC9841229

Abstract Article PDF–3.2M

Select item 973747514.

Orphan Nuclear Receptor Nur77 Mediates the Lethal Endoplasmic Reticulum Stress and Therapeutic Efficacy of Cryptomeridiol in Hepatocellular Carcinoma

Xudan Li, Quancheng Chen, Jie Liu, Shenjin Lai, Minda Zhang, Tidong Zhen, Hongyu Hu, Xiang Gao, Alice S. T. Wong, Jin-Zhang Zeng

Cells. 2022 Dec; 11(23): 3870. Published online 2022 Dec 1. doi: 10.3390/cells11233870

PMCID:: PMC9737475

Abstract Article PDF–4.0M

Select item 955055615.

Nur77通过NF-κB/IL-6信号途径促进胃癌细胞的侵袭与迁移

李蔚, 石永康, 郭玉华, 田声望

Nan Fang Yi Ke Da Xue Xue Bao. 2022 Sep 20; 42(9): 1410–1417. Chinese. doi: 10.12122/j.issn.1673-4254.2022.09.19

PMCID:: PMC9550556

Abstract Article PDF–2.4M

Select item 927941016.

Histone demethylase JMJD3 downregulation protects against aberrant force-induced osteoarthritis through epigenetic control of NR4A1

Yu Jin, Zhen Liu, Zhenxia Li, Hairui Li, Cheng Zhu, Ruomei Li, Ting Zhou, Bing Fang

Int J Oral Sci. 2022; 14: 34. Published online 2022 Jul 14. doi: 10.1038/s41368-022-00190-4

PMCID:: PMC9279410

Abstract Article PDF–5.9M

Select item 922654917.

Loss of Lipocalin 10 Exacerbates Diabetes-Induced Cardiomyopathy via Disruption of Nr4a1-Mediated Anti-Inflammatory Response in Macrophages

Qianqian Li, Yutian Li, Wei Huang, Xiaohong Wang, Zhenling Liu, Jing Chen, Yanbo Fan, Tianqing Peng, Sakthivel Sadayappan, Yigang Wang, Guo-Chang Fan

Front Immunol. 2022; 13: 930397. Published online 2022 Jun 10. doi: 10.3389/fimmu.2022.930397

PMCID:: PMC9226549

Abstract Article PDF–6.8M

Select item 866505018.

Nuclear Receptor 4A1 (NR4A1) Antagonists Target Paraspeckle Component 1 (PSPC1) in Cancer Cells

Kumaravel Mohankumar, Rupesh Shrestha, Stephen Safe

Mol Carcinog. Author manuscript; available in PMC 2023 Jan 1.

Published in final edited form as: Mol Carcinog. 2022 Jan; 61(1): 73–84. Published online 2021 Oct 26. doi: 10.1002/mc.23362

PMCID:: PMC8665050

Abstract Article PDF–2.7M

Select item 854946519.

NR4A1 regulates expression of immediate early genes, suppressing replication stress in cancer

Hongshan Guo, Gabriel Golczer, Ben S. Wittner, Adam Langenbucher, Marcus Zachariah, Taronish D. Dubash, Xin Hong, Valentine Comaills, Risa Burr, Richard Y. Ebright, Elad Horwitz, Joanna A. Vuille, Soroush Hajizadeh, Devon F. Wiley, Brittany A. Reeves, Jia-min Zhang, Kira L. Niederhoffer, Chenyue Lu, Benjamin Wesley, Uyen Ho, Linda T. Nieman, Mehmet Toner, Shobha Vasudevan, Lee Zou, Raul Mostoslavsky, Shyamala Maheswaran, Michael S. Lawrence, Daniel A. Haber

Mol Cell. Author manuscript; available in PMC 2022 Oct 7.

Published in final edited form as: Mol Cell. 2021 Oct 7; 81(19): 4041–4058.e15. doi: 10.1016/j.molcel.2021.09.016

PMCID:: PMC8549465

Abstract Article PDF–2.7M

Select item 852656720.

SPDEF suppresses head and neck squamous cell carcinoma progression by transcriptionally activating NR4A1

Yanting Wang, Xianyue Ren, Weiyu Li, Ruoyan Cao, Suyang Liu, Laibo Jiang, Bin Cheng, Juan Xia

Int J Oral Sci. 2021; 13: 33. Published online 2021 Oct 20. doi: 10.1038/s41368-021-00138-0

PMCID:: PMC8526567

Abstract Article PDF–3.3M

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