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Select item 102333681.

A systematic proximity ligation approach to studying protein‐substrate specificity identifies the substrate spectrum of the Ssh1 translocon

Nir Cohen, Naama Aviram, Maya Schuldiner

EMBO J. 2023 Jun; 42(11): e113385. Published online 2023 Apr 19. doi: 10.15252/embj.2022113385

PMCID:: PMC10233368

Abstract Article PDF–1.2M

Select item 92098112.

New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources

Stacia R Engel, Edith D Wong, Robert S Nash, Suzi Aleksander, Micheal Alexander, Eric Douglass, Kalpana Karra, Stuart R Miyasato, Matt Simison, Marek S Skrzypek, Shuai Weng, J Michael Cherry

Genetics. 2022 Apr; 220(4): iyab224. Published online 2021 Dec 13. doi: 10.1093/genetics/iyab224

PMCID:: PMC9209811

Abstract Article PDF–818K

Select item 79545263.

DDK regulates replication initiation by controlling the multiplicity of Cdc45-GINS binding to Mcm2-7

Lorraine De Jesús-Kim, Larry J Friedman, Marko Lõoke, Christian K Ramsoomair, Jeff Gelles, Stephen P Bell

eLife. 2021; 10: e65471. Published online 2021 Feb 22. doi: 10.7554/eLife.65471

PMCID:: PMC7954526

Abstract Article PDF–3.6M

Select item 75074024.

Systematic analysis of bypass suppression of essential genes

Jolanda van Leeuwen, Carles Pons, Guihong Tan, Zi Yang Wang, Jing Hou, Jochen Weile, Marinella Gebbia, Wendy Liang, Ermira Shuteriqi, Zhijian Li, Maykel Lopes, Matej Ušaj, Andreia Dos Santos Lopes, Natascha van Lieshout, Chad L Myers, Frederick P Roth, Patrick Aloy, Brenda J Andrews, Charles Boone

Mol Syst Biol. 2020 Sep; 16(9): e9828. Published online 2020 Sep 17. doi: 10.15252/msb.20209828

PMCID:: PMC7507402

Abstract Article PDF–1.9M

Select item 72289705.

DNA polymerase ε relies on a unique domain for efficient replisome assembly and strand synthesis

Xiangzhou Meng, Lei Wei, Sujan Devbhandari, Tuo Zhang, Jenny Xiang, Dirk Remus, Xiaolan Zhao

Nat Commun. 2020; 11: 2437. Published online 2020 May 15. doi: 10.1038/s41467-020-16095-x

PMCID:: PMC7228970

Abstract Article PDF–2.7M

Select item 68244636.

Checkpoint inhibition of origin firing prevents DNA topological stress

Esther C. Morafraile, Christine Hänni, George Allen, Theresa Zeisner, Caroline Clarke, Mark C. Johnson, Miguel M. Santos, Lauren Carroll, Nicola E. Minchell, Jonathan Baxter, Peter Banks, Dave Lydall, Philip Zegerman

Genes Dev. 2019 Nov 1; 33(21-22): 1539–1554. doi: 10.1101/gad.328682.119

PMCID:: PMC6824463

Abstract Article PDF–5.0M

Select item 67954777.

The effects of manipulating levels of replication initiation factors on origin firing efficiency in yeast

Kelsey L. Lynch, Gina M. Alvino, Elizabeth X. Kwan, Bonita J. Brewer, M. K. Raghuraman

PLoS Genet. 2019 Oct; 15(10): e1008430. Published online 2019 Oct 4. doi: 10.1371/journal.pgen.1008430

PMCID:: PMC6795477

Abstract Article PDF–5.4M

Select item 65326478.

Transcriptional repression of CDC6 and SLD2 during meiosis is associated with production of short heterogeneous RNA isoforms

David V. Phizicky, Stephen P. Bell

Chromosoma. Author manuscript; available in PMC 2019 Dec 1.

Published in final edited form as: Chromosoma. 2018 Dec; 127(4): 515–527. Published online 2018 Oct 1. doi: 10.1007/s00412-018-0681-x

PMCID:: PMC6532647

Abstract Article PDF–1.7M

Select item 58054099.

Multiple kinases inhibit origin licensing and helicase activation to ensure reductive cell division during meiosis

David V Phizicky, Luke E Berchowitz, Stephen P Bell

eLife. 2018; 7: e33309. Published online 2018 Feb 1. doi: 10.7554/eLife.33309

PMCID:: PMC5805409

Abstract Article PDF–3.1M

Select item 562383510.

Pre‐initiation complex assembly functions as a molecular switch that splits the Mcm2‐7 double hexamer

Mayumi Miyazawa‐Onami, Hiroyuki Araki, Seiji Tanaka

EMBO Rep. 2017 Oct; 18(10): 1752–1761. Published online 2017 Aug 17. doi: 10.15252/embr.201744206

PMCID:: PMC5623835

Abstract Article PDF–944K

Select item 547375511.

Mapping the Synthetic Dosage Lethality Network of CDK1/CDC28

Christine Zimmermann, Ignacio Garcia, Manja Omerzu, Pierre Chymkowitch, Beibei Zhang, Jorrit M. Enserink

G3 (Bethesda) 2017 Jun; 7(6): 1753–1766. Published online 2017 Apr 18. doi: 10.1534/g3.117.042317

Correction in:: G3 (Bethesda). 2019 Aug; 9(8): 2787.

PMCID:: PMC5473755

Abstract Article PDF–2.7M

Select item 541510612.

Dpb11 may function with RPA and DNA to initiate DNA replication

Irina Bruck, Nalini Dhingra, Matthew P. Martinez, Daniel L. Kaplan

PLoS One. 2017; 12(5): e0177147. Published online 2017 May 3. doi: 10.1371/journal.pone.0177147

PMCID:: PMC5415106

Abstract Article PDF–6.6M

Select item 520434813.

A novel translational control mechanism involving RNA structures within coding sequences

Jennifer Jungfleisch, Danny D. Nedialkova, Ivan Dotu, Katherine E. Sloan, Neus Martinez-Bosch, Lukas Brüning, Emanuele Raineri, Pilar Navarro, Markus T. Bohnsack, Sebastian A. Leidel, Juana Díez

Genome Res. 2017 Jan; 27(1): 95–106. doi: 10.1101/gr.209015.116

Correction in:: Genome Res. 2017 Apr; 27(4): 663.

PMCID:: PMC5204348

Abstract Article PDF–1.3M

Select item 492216214.

Plasma membrane/cell wall perturbation activates a novel cell cycle checkpoint during G1 in Saccharomyces cerevisiae

Keiko Kono, Amr Al-Zain, Lea Schroeder, Makoto Nakanishi, Amy E. Ikui

Proc Natl Acad Sci U S A. 2016 Jun 21; 113(25): 6910–6915. Published online 2016 Jun 7. doi: 10.1073/pnas.1523824113

PMCID:: PMC4922162

Abstract Article PDF–968K

Select item 487446815.

Regulated Eukaryotic DNA Replication Origin Firing with Purified Proteins

Joseph T.P. Yeeles, Tom D. Deegan, Agnieszka Janska, Anne Early, John F. X. Diffley

Nature. Author manuscript; available in PMC 2016 May 20.

Published in final edited form as: Nature. 2015 Mar 26; 519(7544): 431–435. Published online 2015 Mar 4. doi: 10.1038/nature14285

PMCID:: PMC4874468

Abstract Article PDF–3.2M

Select item 466639116.

A reconstituted system reveals how activating and inhibitory interactions control DDK dependent assembly of the eukaryotic replicative helicase

M. Carmen Herrera, Silvia Tognetti, Alberto Riera, Juergen Zech, Pippa Clarke, Alejandra Fernández-Cid, Christian Speck

Nucleic Acids Res. 2015 Dec 2; 43(21): 10238–10250. Published online 2015 Sep 3. doi: 10.1093/nar/gkv881

PMCID:: PMC4666391

Abstract Article PDF–7.9M

Select item 461603917.

Integrated multi-omics analyses reveal the pleiotropic nature of the control of gene expression by Puf3p

Christopher J. Kershaw, Joseph L. Costello, David Talavera, William Rowe, Lydia M. Castelli, Paul F. G. Sims, Christopher M. Grant, Mark P. Ashe, Simon J. Hubbard, Graham D. Pavitt

Sci Rep. 2015; 5: 15518. Published online 2015 Oct 23. doi: 10.1038/srep15518