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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 105096692.

Mecom mutation related to radioulnar synostosis with amegakaryocytic thrombocytopenia reduces HSPCs in mice

Koki Nagai, Tetsuya Niihori, Akihiko Muto, Yoshikazu Hayashi, Taiki Abe, Kazuhiko Igarashi, Yoko Aoki

Blood Adv. 2023 Sep 26; 7(18): 5409–5420. Published online 2023 Apr 26. doi: 10.1182/bloodadvances.2022008462

PMCID:: PMC10509669

Abstract Article PDF–2.6M

Select item 104925103.

Highly efficient Runx1 enhancer eR1-mediated genetic engineering for fetal, child and adult hematopoietic stem cells

Cai Ping Koh, Avinash Govind Bahirvani, Chelsia Qiuxia Wang, Tomomasa Yokomizo, Cherry Ee Lin Ng, Linsen Du, Vinay Tergaonkar, Dominic Chih-Cheng Voon, Hiroaki Kitamura, Hiroki Hosoi, Takashi Sonoki, Mok Meng Huang Michelle, Lii Jye Tan, Akiko Niibori-Nambu, Yi Zhang, Archibald S. Perkins, Zakir Hossain, Daniel G. Tenen, Yoshiaki Ito, Byrappa Venkatesh, Motomi Osato

Gene. Author manuscript; available in PMC 2023 Sep 9.

Published in final edited form as: Gene. 2023 Jan 30; 851: 147049. Published online 2022 Nov 13. doi: 10.1016/j.gene.2022.147049

PMCID:: PMC10492510

Abstract Article PDF–1.3M

Select item 103904924.

Three-dimensional molecular architecture of mouse organogenesis

Fangfang Qu, Wenjia Li, Jian Xu, Ruifang Zhang, Jincan Ke, Xiaodie Ren, Xiaogao Meng, Lexin Qin, Jingna Zhang, Fangru Lu, Xin Zhou, Xi Luo, Zhen Zhang, Minhan Wang, Guangming Wu, Duanqing Pei, Jiekai Chen, Guizhong Cui, Shengbao Suo, Guangdun Peng

Nat Commun. 2023; 14: 4599. Published online 2023 Jul 31. doi: 10.1038/s41467-023-40155-7

PMCID:: PMC10390492

Abstract Article PDF–13M

Select item 101398675.

EVI1 exerts distinct roles in AML via ERG and cyclin D1 promoting a chemoresistant and immune-suppressive environment

Yosuke Masamoto, Akira Chiba, Hideaki Mizuno, Toshiya Hino, Hiroki Hayashida, Tomohiko Sato, Masashige Bando, Katsuhiko Shirahige, Mineo Kurokawa

Blood Adv. 2023 Apr 25; 7(8): 1577–1593. Published online 2022 Oct 27. doi: 10.1182/bloodadvances.2022008018

PMCID:: PMC10139867

Abstract Article PDF–1.9M

Select item 98106646.

Single-cell transcriptomic analysis reveals diversity within mammalian spinal motor neurons

Ee Shan Liau, Suoqin Jin, Yen-Chung Chen, Wei-Szu Liu, Maëliss Calon, Stéphane Nedelec, Qing Nie, Jun-An Chen

Nat Commun. 2023; 14: 46. Published online 2023 Jan 3. doi: 10.1038/s41467-022-35574-x

PMCID:: PMC9810664

Abstract Article PDF–11M

Select item 95556197.

Trans-cortical vessels in the mouse temporal bulla bone are a means to recruit myeloid cells in chronic otitis media and limit peripheral leukogram changes

Ali Azar, Mahmood F. Bhutta, Jorge Del-Pozo, Elspeth Milne, Michael Cheeseman

Front Genet. 2022; 13: 985214. Published online 2022 Sep 28. doi: 10.3389/fgene.2022.985214

PMCID:: PMC9555619

Abstract Article PDF–5.1M

Select item 94120078.

Aberrant EVI1 splicing contributes to EVI1-rearranged leukemia

Atsushi Tanaka, Taizo A. Nakano, Masaki Nomura, Hiromi Yamazaki, Jan P. Bewersdorf, Roger Mulet-Lazaro, Simon Hogg, Bo Liu, Alex Penson, Akihiko Yokoyama, Weijia Zang, Marije Havermans, Miho Koizumi, Yasutaka Hayashi, Hana Cho, Akinori Kanai, Stanley C. Lee, Muran Xiao, Yui Koike, Yifan Zhang, Miki Fukumoto, Yumi Aoyama, Tsuyoshi Konuma, Hiroyoshi Kunimoto, Toshiya Inaba, Hideaki Nakajima, Hiroaki Honda, Hiroshi Kawamoto, Ruud Delwel, Omar Abdel-Wahab, Daichi Inoue

Blood. 2022 Aug 25; 140(8): 875–888. doi: 10.1182/blood.2021015325

PMCID:: PMC9412007

Abstract Article

Select item 89909269.

The EDA-deficient mouse has Zymbal's gland hypoplasia and acute otitis externa

Jorge del-Pozo, Denis J. Headon, James D. Glover, Ali Azar, Sonia Schuepbach-Mallepell, Mahmood F. Bhutta, Jon Riddell, Scott Maxwell, Elspeth Milne, Pascal Schneider, Michael Cheeseman

Dis Model Mech. 2022 Mar 1; 15(3): dmm049034. Published online 2022 Mar 30. doi: 10.1242/dmm.049034

PMCID:: PMC8990926

Abstract Article

Select item 891878710.

PRDM paralogs antagonistically balance Wnt/β-catenin activity during craniofacial chondrocyte differentiation

Lomeli C. Shull, Ezra S. Lencer, Hyun Min Kim, Susumu Goyama, Mineo Kurokawa, James C. Costello, Kenneth Jones, Kristin B. Artinger

Development. 2022 Feb 15; 149(4): dev200082. Published online 2022 Feb 24. doi: 10.1242/dev.200082

PMCID:: PMC8918787

Abstract Article

Select item 885463311.

The histone demethylase Kdm6b regulates subtype diversification of mouse spinal motor neurons during development

Wenxian Wang, Hyeyoung Cho, Jae W. Lee, Soo-Kyung Lee

Nat Commun. 2022; 13: 958. Published online 2022 Feb 17. doi: 10.1038/s41467-022-28636-7

PMCID:: PMC8854633

Abstract Article PDF–14M

Select item 876331712.

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1–CoREST interactome during embryonic stem cell differentiation

Claire E. Barnes, David M. English, Megan Broderick, Mark O. Collins, Shaun M. Cowley

Mol Omics. 2022 Jan 17; 18(1): 31–44. Published online 2021 Oct 14. doi: 10.1039/d1mo00236h

PMCID:: PMC8763317

Abstract Article

Select item 874093513.

Limb development genes underlie variation in human fingerprint patterns

Jinxi Li, James D. Glover, Haiguo Zhang, Meifang Peng, Jingze Tan, Chandana Basu Mallick, Dan Hou, Yajun Yang, Sijie Wu, Yu Liu, Qianqian Peng, Shijie C. Zheng, Edie I. Crosse, Alexander Medvinsky, Richard A. Anderson, Helen Brown, Ziyu Yuan, Shen Zhou, Yanqing Xu, John P. Kemp, Yvonne Y.W. Ho, Danuta Z. Loesch, Lizhong Wang, Yingxiang Li, Senwei Tang, Xiaoli Wu, Robin G. Walters, Kuang Lin, Ruogu Meng, Jun Lv, Jonathan M. Chernus, Katherine Neiswanger, Eleanor Feingold, David M. Evans, Sarah E. Medland, Nicholas G. Martin, Seth M. Weinberg, Mary L. Marazita, Gang Chen, Zhengming Chen, Yong Zhou, Michael Cheeseman, Lan Wang, Li Jin, Denis J. Headon, Sijia Wang

Cell. 2022 Jan 6; 185(1): 95–112.e18. doi: 10.1016/j.cell.2021.12.008

PMCID:: PMC8740935

Abstract Article

Select item 848620414.

Evi1 upregulates Fbp1 and supports progression of acute myeloid leukemia through pentose phosphate pathway activation

Hideaki Mizuno, Junji Koya, Yosuke Masamoto, Yuki Kagoya, Mineo Kurokawa

Cancer Sci. 2021 Oct; 112(10): 4112–4126. Published online 2021 Aug 22. doi: 10.1111/cas.15098

PMCID:: PMC8486204

Abstract Article PDF–2.0M

Select item 842839315.

Mds1^CreERT2, an inducible Cre allele specific to adult-repopulating hematopoietic stem cells

Yi Zhang, Kathleen E. McGrath, Edward Ayoub, Paul D. Kingsley, Hongbo Yu, Kate Fegan, Kelly A. McGlynn, Sarah Rudzinskas, James Palis, Archibald S. Perkins

Cell Rep. Author manuscript; available in PMC 2021 Sep 9.

Published in final edited form as: Cell Rep. 2021 Aug 17; 36(7): 109562. doi: 10.1016/j.celrep.2021.109562

PMCID:: PMC8428393

Abstract Article PDF–1.5M

Select item 840821916.

MECOM permits pancreatic acinar cell dedifferentiation avoiding cell death under stress conditions

Elyne Backx, Elke Wauters, Jonathan Baldan, Mathias Van Bulck, Ellis Michiels, Yves Heremans, Diedert Luc De Paep, Mineo Kurokawa, Susumu Goyama, Luc Bouwens, Patrick Jacquemin, Isabelle Houbracken, Ilse Rooman

Cell Death Differ. 2021 Sep; 28(9): 2601–2615. Published online 2021 Mar 24. doi: 10.1038/s41418-021-00771-6

PMCID:: PMC8408219

Abstract Article PDF–5.4M

Select item 793877017.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 758245718.

Deletion of the Prdm3 Gene Causes a Neuronal Differentiation Deficiency in P19 Cells

Paweł Leszczyński, Magdalena Śmiech, Aamir Salam Teeli, Effi Haque, Robert Viger, Hidesato Ogawa, Mariusz Pierzchała, Hiroaki Taniguchi

Int J Mol Sci. 2020 Oct; 21(19): 7192. Published online 2020 Sep 29. doi: 10.3390/ijms21197192

PMCID:: PMC7582457

Abstract Article PDF–2.9M

Select item 719835819.

The conserved and divergent roles of Prdm3 and Prdm16 in zebrafish and mouse craniofacial development

Lomeli Carpio Shull, Rwik Sen, Johannes Menzel, Susumu Goyama, Mineo Kurokawa, Kristin Bruk Artinger

Dev Biol. Author manuscript; available in PMC 2021 May 15.

Published in final edited form as: Dev Biol. 2020 May 15; 461(2): 132–144. Published online 2020 Feb 8. doi: 10.1016/j.ydbio.2020.02.006

PMCID:: PMC7198358

Abstract Article PDF–1.8M

Select item 718929420.

EVI1 and GATA2 misexpression induced by inv(3)(q21q26) contribute to megakaryocyte-lineage skewing and leukemogenesis

Ayaka Yamaoka, Mikiko Suzuki, Saori Katayama, Daiki Orihara, James Douglas Engel, Masayuki Yamamoto

Blood Adv. 2020 Apr 28; 4(8): 1722–1736. Published online 2020 Apr 24. doi: 10.1182/bloodadvances.2019000978

PMCID:: PMC7189294

Abstract Article PDF–2.4M

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