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Select item 108724771.

Protein interaction network revealed by quantitative proteomic analysis links TFIIB to multiple aspects of the transcription cycle

Michael J. O’Brien, Athar Ansari

Biochim Biophys Acta Proteins Proteom. Author manuscript; available in PMC 2024 Feb 16.

Published in final edited form as: Biochim Biophys Acta Proteins Proteom. 2024 Jan 1; 1872(1): 140968. Published online 2023 Oct 19. doi: 10.1016/j.bbapap.2023.140968

PMCID:: PMC10872477

Abstract Article PDF–1.7M

Select item 107001382.

The social and structural architecture of the yeast protein interactome

André C. Michaelis, Andreas-David Brunner, Maximilian Zwiebel, Florian Meier, Maximilian T. Strauss, Isabell Bludau, Matthias Mann

Nature. 2023; 624(7990): 192–200. Published online 2023 Nov 15. doi: 10.1038/s41586-023-06739-5

PMCID:: PMC10700138

Abstract Article PDF–20M

Select item 105166423.

ISW1a modulates cohesin distribution in centromeric and pericentromeric regions

Ireneusz Litwin, Małgorzata Nowicka, Katarzyna Markowska, Ewa Maciaszczyk-Dziubińska, Paulina Tomaszewska, Robert Wysocki, Karol Kramarz

Nucleic Acids Res. 2023 Sep 22; 51(17): 9101–9121. Published online 2023 Jul 24. doi: 10.1093/nar/gkad612

PMCID:: PMC10516642

Abstract Article PDF–2.8M

Select item 102977004.

The Hsp90 molecular chaperone governs client proteins by targeting intrinsically disordered regions

Janhavi A. Kolhe, Neethu L. Babu, Brian C. Freeman

Mol Cell. Author manuscript; available in PMC 2024 Jun 15.

Published in final edited form as: Mol Cell. 2023 Jun 15; 83(12): 2035–2044.e7. Published online 2023 Jun 8. doi: 10.1016/j.molcel.2023.05.021

PMCID:: PMC10297700

Abstract Article PDF–2.0M

Select item 102249585.

Cryo-EM structure of the Saccharomyces cerevisiae Rpd3L histone deacetylase complex

Avinash B. Patel, Jinkang Qing, Kelly H. Tam, Sara Zaman, Maria Luiso, Ishwar Radhakrishnan, Yuan He

Nat Commun. 2023; 14: 3061. Published online 2023 May 27. doi: 10.1038/s41467-023-38687-z

PMCID:: PMC10224958

Abstract Article PDF–4.2M

Select item 99950776.

The TORC1 activates Rpd3L complex to deacetylate Ino80 and H2A.Z and repress autophagy

Xin Li, Qianyun Mei, Qi Yu, Min Wang, Fei He, Duncheng Xiao, Huan Liu, Feng Ge, Xilan Yu, Shanshan Li

Sci Adv. 2023 Mar; 9(10): eade8312. Published online 2023 Mar 8. doi: 10.1126/sciadv.ade8312

PMCID:: PMC9995077

Abstract Article PDF–2.7M

Select item 96380287.

Yeast Smy2 and its human homologs GIGYF1 and -2 regulate Cdc48/VCP function during transcription stress

Michelle Harreman Lehner, Jane Walker, Kotryna Temcinaite, Anna Herlihy, Michael Taschner, Adam C. Berger, Anita H. Corbett, A. Barbara Dirac Svejstrup, Jesper Q. Svejstrup

Cell Rep. 2022 Oct 25; 41(4): 111536. Published online 2022 Oct 25. doi: 10.1016/j.celrep.2022.111536

PMCID:: PMC9638028

Abstract Article

Select item 96309868.

A balancing act: interactions within NuA4/TIP60 regulate picNuA4 function in Saccharomyces cerevisiae and humans

Phoebe Y T Lu, Alyssa C Kirlin, Maria J Aristizabal, Hilary T Brewis, Nancy Lévesque, Dheva T Setiaputra, Nikita Avvakumov, Joris J Benschop, Marian Groot Koerkamp, Frank C P Holstege, Nevan J Krogan, Calvin K Yip, Jacques Côté, Michael S Kobor

Genetics. 2022 Nov; 222(3): iyac136. Published online 2022 Sep 6. doi: 10.1093/genetics/iyac136

PMCID:: PMC9630986

Abstract Article PDF–2.2M

Select item 92860239.

Mediator recruits the cohesin loader Scc2 to RNA Pol II-transcribed genes and promotes sister chromatid cohesion

Mark Mattingly, Chris Seidel, Sofía Muñoz, Yan Hao, Ying Zhang, Zhihui Wen, Laurence Florens, Frank Uhlmann, Jennifer L. Gerton

Curr Biol. 2022 Jul 11; 32(13): 2884–2896.e6. doi: 10.1016/j.cub.2022.05.019

PMCID:: PMC9286023

Abstract Article

Select item 920981110.

New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources

Stacia R Engel, Edith D Wong, Robert S Nash, Suzi Aleksander, Micheal Alexander, Eric Douglass, Kalpana Karra, Stuart R Miyasato, Matt Simison, Marek S Skrzypek, Shuai Weng, J Michael Cherry

Genetics. 2022 Apr; 220(4): iyab224. Published online 2021 Dec 13. doi: 10.1093/genetics/iyab224

PMCID:: PMC9209811

Abstract Article PDF–818K

Select item 857106311.

Systems-level effects of allosteric perturbations to a model molecular switch

Tina Perica, Christopher J. P. Mathy, Jiewei Xu, Gwendolyn M. Jang, Yang Zhang, Robyn Kaake, Noah Ollikainen, Hannes Braberg, Danielle L. Swaney, David G. Lambright, Mark J. S. Kelly, Nevan J. Krogan, Tanja Kortemme

Nature. Author manuscript; available in PMC 2022 May 1.

Published in final edited form as: Nature. 2021 Nov; 599(7883): 152–157. Published online 2021 Oct 13. doi: 10.1038/s41586-021-03982-6

PMCID:: PMC8571063

Abstract Article PDF–2.7M

Select item 821475912.

Genome-wide imaging screen uncovers molecular determinants of arsenite-induced protein aggregation and toxicity

Stefanie Andersson, Antonia Romero, Joana Isabel Rodrigues, Sansan Hua, Xinxin Hao, Therese Jacobson, Vivien Karl, Nathalie Becker, Arghavan Ashouri, Sebastien Rauch, Thomas Nyström, Beidong Liu, Markus J. Tamás

J Cell Sci. 2021 Jun 1; 134(11): jcs258338. Published online 2021 Jun 4. doi: 10.1242/jcs.258338

PMCID:: PMC8214759

Abstract Article

Select item 772147513.

A Selective Autophagy Pathway for Phase-Separated Endocytic Protein Deposits

Florian Wilfling, Chia-Wei Lee, Philipp S. Erdmann, Yumei Zheng, Dawafuti Sherpa, Stefan Jentsch, Boris Pfander, Brenda A. Schulman, Wolfgang Baumeister

Mol Cell. 2020 Dec 3; 80(5): 764–778.e7. doi: 10.1016/j.molcel.2020.10.030

PMCID:: PMC7721475

Abstract Article

Select item 771875114.

Comprehensive Synthetic Genetic Array Analysis of Alleles That Interact with Mutation of the Saccharomyces cerevisiae RecQ Helicases Hrq1 and Sgs1

Elsbeth Sanders, Phoebe A. Nguyen, Cody M. Rogers, Matthew L. Bochman

G3 (Bethesda) 2020 Dec; 10(12): 4359–4368. Published online 2020 Oct 28. doi: 10.1534/g3.120.401709

PMCID:: PMC7718751

Abstract Article PDF–1.2M

Select item 750740215.

Systematic analysis of bypass suppression of essential genes

Jolanda van Leeuwen, Carles Pons, Guihong Tan, Zi Yang Wang, Jing Hou, Jochen Weile, Marinella Gebbia, Wendy Liang, Ermira Shuteriqi, Zhijian Li, Maykel Lopes, Matej Ušaj, Andreia Dos Santos Lopes, Natascha van Lieshout, Chad L Myers, Frederick P Roth, Patrick Aloy, Brenda J Andrews, Charles Boone

Mol Syst Biol. 2020 Sep; 16(9): e9828. Published online 2020 Sep 17. doi: 10.15252/msb.20209828

PMCID:: PMC7507402

Abstract Article PDF–1.9M

Select item 732543516.

A genetic interaction map centered on cohesin reveals auxiliary factors involved in sister chromatid cohesion in S. cerevisiae

Su Ming Sun, Amandine Batté, Mireille Elmer, Sophie C. van der Horst, Tibor van Welsem, Gordon Bean, Trey Ideker, Fred van Leeuwen, Haico van Attikum

J Cell Sci. 2020 May 15; 133(10): jcs237628. Published online 2020 May 22. doi: 10.1242/jcs.237628

PMCID:: PMC7325435

Abstract Article

Select item 666992217.

Endosome and Golgi‐associated degradation (EGAD) of membrane proteins regulates sphingolipid metabolism

Oliver Schmidt, Yannick Weyer, Verena Baumann, Michael A Widerin, Sebastian Eising, Mihaela Angelova, Alexander Schleiffer, Leopold Kremser, Herbert Lindner, Matthias Peter, Florian Fröhlich, David Teis

EMBO J. 2019 Aug 1; 38(15): e101433. Published online 2019 May 27. doi: 10.15252/embj.2018101433

PMCID:: PMC6669922

Abstract Article PDF–2.8M

Select item 654556218.

Slx5/Slx8‐dependent ubiquitin hotspots on chromatin contribute to stress tolerance

Markus Höpfler, Maximilian J Kern, Tobias Straub, Roman Prytuliak, Bianca H Habermann, Boris Pfander, Stefan Jentsch

EMBO J. 2019 Jun 3; 38(11): e100368. Published online 2019 Apr 23. doi: 10.15252/embj.2018100368

PMCID:: PMC6545562

Abstract Article PDF–2.3M

Select item 622256919.

Combinatorial Genetic Control of Rpd3S Through Histone H3K4 and H3K36 Methylation in Budding Yeast

Kwan Yin Lee, Mathieu Ranger, Marc D. Meneghini

G3 (Bethesda) 2018 Nov; 8(11): 3411–3420. Published online 2018 Aug 29. doi: 10.1534/g3.118.200589

PMCID:: PMC6222569

Abstract Article PDF–1.8M

Select item 592252820.

Global analysis of genetic circuitry and adaptive mechanisms enabling resistance to the azole antifungal drugs

Harley O’Connor Mount, Nicole M. Revie, Robert T. Todd, Kaitlin Anstett, Cathy Collins, Michael Costanzo, Charles Boone, Nicole Robbins, Anna Selmecki, Leah E. Cowen

PLoS Genet. 2018 Apr; 14(4): e1007319. Published online 2018 Apr 27. doi: 10.1371/journal.pgen.1007319