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Items: 1 to 20 of 61

1.
Substrate recognition mechanism of the endoplasmic reticulum-associated ubiquitin ligase Doa10
Kevin Wu, Samuel Itskanov, Diane L. Lynch, Yuanyuan Chen, Aasha Turner, James C. Gumbart, Eunyong Park
Nat Commun. 2024; 15: 2182. Published online 2024 Mar 11. doi: 10.1038/s41467-024-46409-2
PMCID:
PMC10928120
AbstractArticlePDF–5.2M
2.
Doa10/MARCH6 architecture interconnects E3 ligase activity with lipid-binding transmembrane channel to regulate SQLE
J. Josephine Botsch, Roswitha Junker, Michèle Sorgenfrei, Patricia P. Ogger, Luca Stier, Susanne von Gronau, Peter J. Murray, Markus A. Seeger, Brenda A. Schulman, Bastian Bräuning
Nat Commun. 2024; 15: 410. Published online 2024 Jan 9. doi: 10.1038/s41467-023-44670-5
PMCID:
PMC10776854
AbstractArticlePDF–6.1M
3.
The social and structural architecture of the yeast protein interactome
André C. Michaelis, Andreas-David Brunner, Maximilian Zwiebel, Florian Meier, Maximilian T. Strauss, Isabell Bludau, Matthias Mann
Nature. 2023; 624(7990): 192–200. Published online 2023 Nov 15. doi: 10.1038/s41586-023-06739-5
PMCID:
PMC10700138
AbstractArticlePDF–20M
4.
A systematic proximity ligation approach to studying protein‐substrate specificity identifies the substrate spectrum of the Ssh1 translocon
Nir Cohen, Naama Aviram, Maya Schuldiner
EMBO J. 2023 Jun; 42(11): e113385. Published online 2023 Apr 19. doi: 10.15252/embj.2022113385
PMCID:
PMC10233368
AbstractArticlePDF–1.2M
5.
Lipid saturation induces degradation of squalene epoxidase for sterol homeostasis and cell survival
Leng-Jie Huang, Rey-Huei Chen
Life Sci Alliance. 2023 Jan; 6(1): e202201612. Published online 2022 Nov 11. doi: 10.26508/lsa.202201612
PMCID:
PMC9652772
AbstractArticlePDF–3.9M
6.
Elements of the ERAD ubiquitin ligase Doa10 regulating sequential poly-ubiquitylation of its targets
Adrian B. Mehrtash, Mark Hochstrasser
iScience. 2022 Nov 18; 25(11): 105351. Published online 2022 Oct 13. doi: 10.1016/j.isci.2022.105351
PMCID:
PMC9619350
AbstractArticlePDF–4.1M
7.
New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources
Stacia R Engel, Edith D Wong, Robert S Nash, Suzi Aleksander, Micheal Alexander, Eric Douglass, Kalpana Karra, Stuart R Miyasato, Matt Simison, Marek S Skrzypek, Shuai Weng, J Michael Cherry
Genetics. 2022 Apr; 220(4): iyab224. Published online 2021 Dec 13. doi: 10.1093/genetics/iyab224
PMCID:
PMC9209811
AbstractArticlePDF–818K
8.
Multiplexed mRNA assembly into ribonucleoprotein particles plays an operon-like role in the control of yeast cell physiology
Rohini R Nair, Dmitry Zabezhinsky, Rita Gelin-Licht, Brian J Haas, Michael CA Dyhr, Hannah S Sperber, Chad Nusbaum, Jeffrey E Gerst
eLife. 2021; 10: e66050. Published online 2021 May 4. doi: 10.7554/eLife.66050
PMCID:
PMC8137142
AbstractArticlePDF–4.6M
9.
Who with whom: functional coordination of E2 enzymes by RING E3 ligases during poly‐ubiquitylation
Christian Lips, Tobias Ritterhoff, Annika Weber, Maria K Janowska, Mandy Mustroph, Thomas Sommer, Rachel E Klevit
EMBO J. 2020 Nov 16; 39(22): e104863. Published online 2020 Oct 5. doi: 10.15252/embj.2020104863
PMCID:
PMC7667886
AbstractArticlePDF–1.5M
10.
The ER-associated protease Ste24 prevents N-terminal signal peptide-independent translocation into the endoplasmic reticulum in Saccharomyces cerevisiae
Akira Hosomi, Kazuko Iida, Toshihiko Cho, Hidetoshi Iida, Masashi Kaneko, Tadashi Suzuki
J Biol Chem. 2020 Jul 24; 295(30): 10406–10419. Published online 2020 Jun 8. doi: 10.1074/jbc.RA120.012575
PMCID:
PMC7383372
AbstractArticlePDF–2.2M
11.
Doa10 is a membrane protein retrotranslocase in ER-associated protein degradation
Claudia C Schmidt, Vedran Vasic, Alexander Stein
eLife. 2020; 9: e56945. Published online 2020 Jun 26. doi: 10.7554/eLife.56945
PMCID:
PMC7319771
AbstractArticlePDF–2.3M
12.
Degradation of integral membrane proteins modified with the photosensitive degron module requires the cytosolic endoplasmic reticulum–associated degradation pathway
Johannes Scheffer, Sophia Hasenjäger, Christof Taxis
Mol Biol Cell. 2019 Sep 15; 30(20): 2558–2570. doi: 10.1091/mbc.E18-12-0754
PMCID:
PMC6740197
AbstractArticlePDF–4.9M
13.
Cooperation of mitochondrial and ER factors in quality control of tail-anchored proteins
Verena Dederer, Anton Khmelinskii, Anna Gesine Huhn, Voytek Okreglak, Michael Knop, Marius K Lemberg
eLife. 2019; 8: e45506. Published online 2019 Jun 7. doi: 10.7554/eLife.45506
PMCID:
PMC6586462
AbstractArticlePDF–4.0M
14.
The anaphase-promoting complex regulates the degradation of the inner nuclear membrane protein Mps3
Bailey A. Koch, Hui Jin, Robert J. Tomko, Jr., Hong-Guo Yu
J Cell Biol. 2019 Mar 4; 218(3): 839–854. doi: 10.1083/jcb.201808024
PMCID:
PMC6400550
AbstractArticlePDF–3.7M
15.
Effect of Sec61 interaction with Mpd1 on endoplasmic reticulum-associated degradation
Fabio Pereira, Mandy Rettel, Frank Stein, Mikhail M. Savitski, Ian Collinson, Karin Römisch
PLoS One. 2019; 14(1): e0211180. Published online 2019 Jan 25. doi: 10.1371/journal.pone.0211180
PMCID:
PMC6347170
AbstractArticlePDF–16M
16.
DNA binding by the MATα2 transcription factor controls its access to alternative ubiquitin-modification pathways
Christopher M. Hickey, Yang Xie, Mark Hochstrasser
Mol Biol Cell. 2018 Mar 1; 29(5): 542–556. doi: 10.1091/mbc.E17-10-0589
PMCID:
PMC6004586
AbstractArticlePDF–1.9M
17.
A global interaction network maps a wiring diagram of cellular function
Michael Costanzo, Benjamin VanderSluis, Elizabeth N. Koch, Anastasia Baryshnikova, Carles Pons, Guihong Tan, Wen Wang, Matej Usaj, Julia Hanchard, Susan D. Lee, Vicent Pelechano, Erin B. Styles, Maximilian Billmann, Jolanda van Leeuwen, Nydia van Dyk, Zhen-Yuan Lin, Elena Kuzmin, Justin Nelson, Jeff S. Piotrowski, Tharan Srikumar, Sondra Bahr, Yiqun Chen, Raamesh Deshpande, Christoph F. Kurat, Sheena C. Li, Zhijian Li, Mojca Mattiazzi Usaj, Hiroki Okada, Natasha Pascoe, Bryan-Joseph San Luis, Sara Sharifpoor, Emira Shuteriqi, Scott W. Simpkins, Jamie Snider, Harsha Garadi Suresh, Yizhao Tan, Hongwei Zhu, Noel Malod-Dognin, Vuk Janjic, Natasa Przulj, Olga G. Troyanskaya, Igor Stagljar, Tian Xia, Yoshikazu Ohya, Anne-Claude Gingras, Brian Raught, Michael Boutros, Lars M. Steinmetz, Claire L. Moore, Adam P. Rosebrock, Amy A. Caudy, Chad L. Myers, Brenda Andrews, Charles Boone
Science. Author manuscript; available in PMC 2017 Oct 30.
Published in final edited form as: Science. 2016 Sep 23; 353(6306): aaf1420. doi: 10.1126/science.aaf1420
PMCID:
PMC5661885
AbstractArticlePDF–2.6M
18.
The Genetic Landscape of a Cell
Michael Costanzo, Anastasia Baryshnikova, Jeremy Bellay, Yungil Kim, Eric D. Spear, Carolyn S. Sevier, Huiming Ding, Judice L.Y. Koh, Kiana Toufighi, Sara Mostafavi, Jeany Prinz, Robert P. St. Onge, Benjamin VanderSluis, Taras Makhnevych, Franco J. Vizeacoumar, Solmaz Alizadeh, Sondra Bahr, Renee L. Brost, Yiqun Chen, Murat Cokol, Raamesh Deshpande, Zhijian Li, Zhen-Yuan Lin, Wendy Liang, Michaela Marback, Jadine Paw, Bryan-Joseph San Luis, Ermira Shuteriqi, Amy Hin Yan Tong, Nydia van Dyk, Iain M. Wallace, Joseph A. Whitney, Matthew T. Weirauch, Guoqing Zhong, Hongwei Zhu, Walid A. Houry, Michael Brudno, Sasan Ragibizadeh, Balázs Papp, Csaba Pál, Frederick P. Roth, Guri Giaever, Corey Nislow, Olga G. Troyanskaya, Howard Bussey, Gary D. Bader, Anne-Claude Gingras, Quaid D. Morris, Philip M. Kim, Chris A. Kaiser, Chad L. Myers, Brenda J. Andrews, Charles Boone
Science. Author manuscript; available in PMC 2017 Sep 15.
Published in final edited form as: Science. 2010 Jan 22; 327(5964): 425–431. doi: 10.1126/science.1180823
PMCID:
PMC5600254
AbstractArticlePDF–2.4M
19.
A Conserved C-terminal Element in the Yeast Doa10 and Human MARCH6 Ubiquitin Ligases Required for Selective Substrate Degradation
Dimitrios Zattas, Jason M. Berk, Stefan G. Kreft, Mark Hochstrasser
J Biol Chem. 2016 Jun 3; 291(23): 12105–12118. Published online 2016 Apr 11. doi: 10.1074/jbc.M116.726877
PMCID:
PMC4933261
AbstractArticlePDF–2.2M
20.
One library to make them all: Streamlining yeast library creation by a SWAp-Tag (SWAT) strategy
Ido Yofe, Uri Weill, Matthias Meurer, Silvia Chuartzman, Einat Zalckvar, Omer Goldman, Shifra Ben-Dor, Conny Schütze, Nils Wiedemann, Michael Knop, Anton Khmelinskii, Maya Schuldiner
Nat Methods. Author manuscript; available in PMC 2016 Sep 22.
Published in final edited form as: Nat Methods. 2016 Apr; 13(4): 371–378. Published online 2016 Feb 29. doi: 10.1038/nmeth.3795
PMCID:
PMC4869835
AbstractArticlePDF–2.7M

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