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Select item 109996961.

Tyrosine-phosphorylated DNER sensitizes insulin signaling in hepatic gluconeogenesis by inducing proteasomal degradation of TRB3

Junfeng Li, Yan Huang, Xinyu Yang, Yuli Cai, Ye Wang, Wenling Dai, Liu Jiang, Changhua Wang, Zhongyuan Wen

Mol Metab. 2024 May; 83: 101927. Published online 2024 Mar 27. doi: 10.1016/j.molmet.2024.101927

PMCID:: PMC10999696

Abstract Article PDF–3.9M

Select item 109176602.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 102008883.

Role of Delta/Notch-like EGF-related receptor in blood glucose homeostasis

Nelmari Ruiz-Otero, Rejji Kuruvilla

Front Endocrinol (Lausanne) 2023; 14: 1161085. Published online 2023 May 8. doi: 10.3389/fendo.2023.1161085

PMCID:: PMC10200888

Abstract Article PDF–7.9M

Select item 91103334.

A conserved YAP/Notch/REST network controls the neuroendocrine cell fate in the lungs

Yan Ting Shue, Alexandros P. Drainas, Nancy Yanzhe Li, Sarah M. Pearsall, Derrick Morgan, Nasa Sinnott-Armstrong, Susan Q. Hipkins, Garry L. Coles, Jing Shan Lim, Anthony E. Oro, Kathryn L. Simpson, Caroline Dive, Julien Sage

Nat Commun. 2022; 13: 2690. Published online 2022 May 16. doi: 10.1038/s41467-022-30416-2

PMCID:: PMC9110333

Abstract Article PDF–7.0M

Select item 89881345.

BET Protein Inhibition Regulates Macrophage Chromatin Accessibility and Microbiota-Dependent Colitis

Michelle Hoffner O’Connor, Ana Berglind, Meaghan M. Kennedy Ng, Benjamin P. Keith, Zachary J. Lynch, Matthew R. Schaner, Erin C. Steinbach, Jeremy Herzog, Omar K. Trad, William R. Jeck, Janelle C. Arthur, Jeremy M. Simon, R. Balfour Sartor, Terrence S. Furey, Shehzad Z. Sheikh

Front Immunol. 2022; 13: 856966. Published online 2022 Mar 24. doi: 10.3389/fimmu.2022.856966

PMCID:: PMC8988134

Abstract Article PDF–13M

Select item 86946986.

Transcriptional profiling of sequentially generated septal neuron fates

Miguel Turrero García, Sarah K Stegmann, Tiara E Lacey, Christopher M Reid, Sinisa Hrvatin, Caleb Weinreb, Manal A Adam, M Aurel Nagy, Corey C Harwell

eLife. 2021; 10: e71545. Published online 2021 Dec 1. doi: 10.7554/eLife.71545

PMCID:: PMC8694698

Abstract Article PDF–5.1M

Select item 83132397.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 67901778.

Diverse spinal commissural neuron populations revealed by fate mapping and molecular profiling using a novel Robo3^Cre mouse

Alastair J. Tulloch, Shaun Teo, Brigett V. Carvajal, Marc Tessier-Lavigne, Alexander Jaworski

J Comp Neurol. Author manuscript; available in PMC 2020 Dec 15.

Published in final edited form as: J Comp Neurol. 2019 Dec 15; 527(18): 2948–2972. Published online 2019 Jun 14. doi: 10.1002/cne.24720

PMCID:: PMC6790177

Abstract Article PDF–3.4M

Select item 65910779.

BET inhibition modifies melanoma infiltrating T cells and enhances response to PD-L1 blockade

Neda Nikbakht, Manoela Tiago, Dan A. Erkes, Inna Chervoneva, Andrew E. Aplin

J Invest Dermatol. Author manuscript; available in PMC 2020 Jul 1.

Published in final edited form as: J Invest Dermatol. 2019 Jul; 139(7): 1612–1615. Published online 2019 Jan 28. doi: 10.1016/j.jid.2018.12.024

PMCID:: PMC6591077

Article PDF–911K

Select item 656202210.

The Notch ligand DNER regulates macrophage IFNγ release in chronic obstructive pulmonary disease

Carolina Ballester-López, Thomas M. Conlon, Zeynep Ertüz, Flavia R. Greiffo, Martin Irmler, Stijn E. Verleden, Johannes Beckers, Isis E. Fernandez, Oliver Eickelberg, Ali Önder Yildirim

EBioMedicine. 2019 May; 43: 562–575. Published online 2019 May 4. doi: 10.1016/j.ebiom.2019.03.054

PMCID:: PMC6562022

Abstract Article PDF–4.1M

Select item 620170111.

DNER and NFIA are Expressed by Developing and Mature AII Amacrine Cells in the Mouse Retina

Patrick W. Keeley, Benjamin E. Reese

J Comp Neurol. Author manuscript; available in PMC 2019 Feb 15.

Published in final edited form as: J Comp Neurol. 2018 Feb 15; 526(3): 467–479. Published online 2017 Nov 11. doi: 10.1002/cne.24345

PMCID:: PMC6201701

Abstract Article PDF–3.3M

Select item 599176812.

Nuclear m⁶A reader YTHDC1 regulates alternative polyadenylation and splicing during mouse oocyte development

Seth D. Kasowitz, Jun Ma, Stephen J. Anderson, N. Adrian Leu, Yang Xu, Brian D. Gregory, Richard M. Schultz, P. Jeremy Wang

PLoS Genet. 2018 May; 14(5): e1007412. Published online 2018 May 25. doi: 10.1371/journal.pgen.1007412

PMCID:: PMC5991768

Abstract Article PDF–19M

Select item 578347713.

DNER modulates the length, polarity and synaptogenesis of spiral ganglion neurons via the Notch signaling pathway

Jintao Du, Xianren Wang, Xiaobo Zhang, Xuemei Zhang, Hongyan Jiang

Mol Med Rep. 2018 Feb; 17(2): 2357–2365. Published online 2017 Nov 20. doi: 10.3892/mmr.2017.8115

PMCID:: PMC5783477

Abstract Article PDF–1.8M

Select item 544875014.

A dual-strategy expression screen for candidate connectivity labels in the developing thalamus

Olivia Bibollet-Bahena, Tatsuya Okafuji, Karsten Hokamp, Guy Tear, Kevin J. Mitchell

PLoS One. 2017; 12(5): e0177977. Published online 2017 May 30. doi: 10.1371/journal.pone.0177977

PMCID:: PMC5448750

Abstract Article PDF–113M

Select item 532404915.

Bromodomain and Extra-Terminal Protein Inhibition Attenuates Neutrophil-dominant Allergic Airway Disease

Michelle L. Manni, Sivanarayana Mandalapu, Andres Salmeron, Jose M. Lora, Jay K. Kolls, John F. Alcorn

Sci Rep. 2017; 7: 43139. Published online 2017 Feb 24. doi: 10.1038/srep43139

PMCID:: PMC5324049

Abstract Article PDF–1.3M

Select item 529582116.

High-throughput discovery of novel developmental phenotypes

Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray

Nature. Author manuscript; available in PMC 2017 Mar 14.

Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356

Correction in:: Nature. 2017 Nov 16; 551(7680): 398.

PMCID:: PMC5295821

Abstract Article PDF–3.0M

Select item 491660317.

Specification of jaw identity by the Hand2 transcription factor

Noriko Funato, Hiroki Kokubo, Masataka Nakamura, Hiromi Yanagisawa, Yumiko Saga

Sci Rep. 2016; 6: 28405. Published online 2016 Jun 22. doi: 10.1038/srep28405

PMCID:: PMC4916603

Abstract Article PDF–3.6M

Select item 461797418.

FoxP1 orchestration of ASD-relevant signaling pathways in the striatum

Daniel J. Araujo, Ashley G. Anderson, Stefano Berto, Wesley Runnels, Matthew Harper, Simon Ammanuel, Michael A. Rieger, Hung-Chung Huang, Kacey Rajkovich, Kristofer W. Loerwald, Joseph D. Dekker, Haley O. Tucker, Joseph D. Dougherty, Jay R. Gibson, Genevieve Konopka

Genes Dev. 2015 Oct 15; 29(20): 2081–2096. doi: 10.1101/gad.267989.115

PMCID:: PMC4617974

Abstract Article PDF–1.3M

Select item 431955919.

A high resolution spatiotemporal atlas of gene expression of the developing mouse brain

Carol L. Thompson, Lydia Ng, Vilas Menon, Salvador Martinez, Chang-Kyu Lee, Katie Glattfelder, Susan M. Sunkin, Alex Henry, Christopher Lau, Chinh Dang, Raquel Garcia-Lopez, Almudena Martinez-Ferre, Ana Pombero, John L.R. Rubenstein, Wayne B. Wakeman, John Hohmann, Nick Dee, Andrew J. Sodt, Rob Young, Kimberly Smith, Thuc-Nghi Nguyen, Jolene Kidney, Leonard Kuan, Andreas Jeromin, Ajamete Kaykas, Jeremy Miller, Damon Page, Geri Orta, Amy Bernard, Zackery Riley, Simon Smith, Paul Wohnoutka, Mike Hawrylycz, Luis Puelles, Allan R. Jones

Neuron. Author manuscript; available in PMC 2015 Jul 16.

Published in final edited form as: Neuron. 2014 Jul 16; 83(2): 309–323. Published online 2014 Jun 19. doi: 10.1016/j.neuron.2014.05.033

PMCID:: PMC4319559

Abstract Article PDF–3.0M

Select item 396495520.

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data

Gautier Koscielny, Gagarine Yaikhom, Vivek Iyer, Terrence F. Meehan, Hugh Morgan, Julian Atienza-Herrero, Andrew Blake, Chao-Kung Chen, Richard Easty, Armida Di Fenza, Tanja Fiegel, Mark Grifiths, Alan Horne, Natasha A. Karp, Natalja Kurbatova, Jeremy C. Mason, Peter Matthews, Darren J. Oakley, Asfand Qazi, Jack Regnart, Ahmad Retha, Luis A. Santos, Duncan J. Sneddon, Jonathan Warren, Henrik Westerberg, Robert J. Wilson, David G. Melvin, Damian Smedley, Steve D. M. Brown, Paul Flicek, William C. Skarnes, Ann-Marie Mallon, Helen Parkinson

Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D802–D809. Published online 2013 Nov 3. doi: 10.1093/nar/gkt977

PMCID:: PMC3964955

Abstract Article PDF–5.7M

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