PMC Links for GEO Profiles (Select 62014184) - PMC

Select item 87487751.

The sphingosine 1-phosphate receptor 2/4 antagonist JTE-013 elicits off-target effects on sphingolipid metabolism

Melissa R. Pitman, Alexander C. Lewis, Lorena T. Davies, Paul A. B. Moretti, Dovile Anderson, Darren J. Creek, Jason A. Powell, Stuart M. Pitson

Sci Rep. 2022; 12: 454. Published online 2022 Jan 10. doi: 10.1038/s41598-021-04009-w

PMCID:: PMC8748775

Abstract Article PDF–1.4M

Select item 81650302.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 71699833.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 67719644.

NCF2, MYO1F, S1PR4, and FCN1 as potential noninvasive diagnostic biomarkers in patients with obstructive coronary artery: A weighted gene co‐expression network analysis

Xian‐Gang Mo, Wei Liu, Yao Yang, Saber Imani, Shan Lu, Guorong Dan, Xuqiang Nie, Jun Yan, Rixing Zhan, Xiaohui Li, Youcai Deng, Bingbo Chen, Yue Cai

J Cell Biochem. 2019 Oct; 120(10): 18219–18235. Published online 2019 Jun 27. doi: 10.1002/jcb.29128

PMCID:: PMC6771964

Abstract Article PDF–3.0M

Select item 67446145.

CD4 T cell sphingosine 1-phosphate receptor (S1PR)1 and S1PR4 and endothelial S1PR2 regulate afferent lymphatic migration

Yanbao Xiong, Wenji Piao, C. Colin Brinkman, Lushen Li, Joseph M. Kulinski, Ana Olivera, Andreane Cartier, Timothy Hla, Keli L. Hippen, Bruce R. Blazar, Susan R. Schwab, Jonathan S. Bromberg

Sci Immunol. Author manuscript; available in PMC 2019 Sep 15.

Published in final edited form as: Sci Immunol. 2019 Mar 15; 4(33): eaav1263. doi: 10.1126/sciimmunol.aav1263

PMCID:: PMC6744614

Abstract Article PDF–3.6M

Select item 55316116.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 54070187.

Shear stress induces Gα_q/11 activation independently of G protein-coupled receptor activation in endothelial cells

Nathaniel G. dela Paz, Benoît Melchior, John A. Frangos

Am J Physiol Cell Physiol. 2017 Apr 1; 312(4): C428–C437. Published online 2017 Feb 1. doi: 10.1152/ajpcell.00148.2016

PMCID:: PMC5407018

Abstract Article

Select item 51450008.

Meta-analysis of rare and common exome chip variants identifies S1PR4 and other loci influencing blood cell traits

Nathan Pankratz, Ursula M Schick, Yi Zhou, Wei Zhou, Tarunveer Singh Ahluwalia, Maria Laura Allende, Paul L Auer, Jette Bork-Jensen, Jennifer A Brody, Ming-Huei Chen, Vinna Clavo, John D Eicher, Niels Grarup, Elliott J Hagedorn, Bella Hu, Kristina Hunker, Andrew D Johnson, Maarten Leusink, Yingchang Lu, Leo-Pekka Lyytikäinen, Ani Manichaikul, Riccardo E Marioni, Mike A Nalls, Raha Pazoki, Albert Vernon Smith, Frank J A van Rooij, Min-Lee Yang, Xiaoling Zhang, Yan Zhang, Folkert W Asselbergs, Eric Boerwinkle, Ingrid B Borecki, Erwin P Bottinger, Mary Cushman, Paul I W de Bakker, Ian J Deary, Liguang Dong, Mary F Feitosa, James S Floyd, Nora Franceschini, Oscar H Franco, Melissa E Garcia, Megan L Grove, Vilmundur Gudnason, Torben Hansen, Tamara B Harris, Albert Hofman, Rebecca D Jackson, Jia Jia, Mika Kähönen, Lenore J Launer, Terho Lehtimäki, David C Liewald, Allan Linneberg, Yongmei Liu, Ruth J F Loos, Vy M Nguyen, Mattijs E Numans, Oluf Pedersen, Bruce M Psaty, Olli T Raitakari, Stephen S Rich, Fernando Rivadeneira, Amanda M Rosa Di Sant, Jerome I Rotter, John M Starr, Kent D Taylor, Betina Heinsbæk Thuesen, Russell P Tracy, Andre G Uitterlinden, Jiansong Wang, Judy Wang, Abbas Dehghan, Yong Huo, L Adrienne Cupples, James G Wilson, Richard L Proia, Leonard I Zon, Christopher J O’Donnell, Alex P Reiner, Santhi K Ganesh

Nat Genet. Author manuscript; available in PMC 2017 Jan 11.

Published in final edited form as: Nat Genet. 2016 Aug; 48(8): 867–876. Published online 2016 Jul 11. doi: 10.1038/ng.3607

PMCID:: PMC5145000

Abstract Article PDF–891K

Select item 41280589.

Lysophospholipid receptor nomenclature review: IUPHAR Review 8

Yasuyuki Kihara, Michael Maceyka, Sarah Spiegel, Jerold Chun

Br J Pharmacol. 2014 Aug; 171(15): 3575–3594. Published online 2014 Jul 12. doi: 10.1111/bph.12678

PMCID:: PMC4128058

Abstract Article PDF–1.2M

Select item 332667910.

Expression of sphingosine 1-phosphate receptor 4 and sphingosine kinase 1 is associated with outcome in oestrogen receptor-negative breast cancer

J Ohotski, J S Long, C Orange, B Elsberger, E Mallon, J Doughty, S Pyne, N J Pyne, J Edwards

Br J Cancer. 2012 Apr 10; 106(8): 1453–1459. Published online 2012 Mar 29. doi: 10.1038/bjc.2012.98

Correction in:: Br J Cancer. 2012 Aug 7; 107(4): 756.

PMCID:: PMC3326679

Abstract Article PDF–499K

Select item 324897611.

Discovery, Design and Synthesis of Novel Potent and Selective Sphingosine-1-Phosphate 4 Receptor (S1P₄-R) Agonists

Miguel Guerrero, Mariangela Urbano, Jian Zhao, Melissa Crisp, Peter Chase, Peter Hodder, Marie-Therese Schaeffer, Steven Brown, Hugh Rosen, Edward Roberts

Bioorg Med Chem Lett. Author manuscript; available in PMC 2013 Jan 1.

Published in final edited form as: Bioorg Med Chem Lett. 2012 Jan 1; 22(1): 537–542. Published online 2011 Nov 4. doi: 10.1016/j.bmcl.2011.10.096