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Items: 1 to 20 of 53

1.
The Distribution of the Genotypes of ABCB1 and CES1 Polymorphisms in Kazakhstani Patients with Atrial Fibrillation Treated with DOAC
Ayan Abdrakhmanov, Ainur Akilzhanova, Aizhan Shaimerdinova, Madina Zhalbinova, Gulnara Tuyakova, Svetlana Abildinova, Rustam Albayev, Bayan Ainabekova, Assel Chinybayeva, Zhanasyl Suleimen, Makhabbat Bekbossynova
Genes (Basel) 2023 Jun; 14(6): 1192. Published online 2023 May 29. doi: 10.3390/genes14061192
PMCID:
PMC10298263
AbstractArticlePDF–273K
2.
Identification of regulatory variants of carboxylesterase 1 (CES1): A proof‐of‐concept study for the application of the Allele‐Specific Protein Expression (ASPE) assay in identifying cis‐acting regulatory genetic polymorphisms
Lucy Her, Jian Shi, Xinwen Wang, Bing He, Logan S. Smith, Hui Jiang, Hao‐Jie Zhu
Proteomics. 2023 Jan; 23(1): 2200176. Published online 2022 Dec 7. doi: 10.1002/pmic.202200176
PMCID:
PMC10077986
AbstractArticlePDF–1.1M
3.
The Influence of Structural Variants of the CES1 Gene on the Pharmacokinetics of Enalapril, Presumably Due to Linkage Disequilibrium with the Intronic rs2244613
Anna Ikonnikova, Ruslan Kazakov, Tatiana Rodina, Artem Dmitriev, Evgeniy Melnikov, Alexander Zasedatelev, Tatiana Nasedkina
Genes (Basel) 2022 Dec; 13(12): 2225. Published online 2022 Nov 27. doi: 10.3390/genes13122225
PMCID:
PMC9778508
AbstractArticlePDF–568K
4.
Spike S1 domain interactome in non-pulmonary systems: A role beyond the receptor recognition
Ilaria Iacobucci, Vittoria Monaco, Luisa Canè, Francesca Bibbò, Valentina Cioffi, Flora Cozzolino, Alfredo Guarino, Massimo Zollo, Maria Monti
Front Mol Biosci. 2022; 9: 975570. Published online 2022 Sep 26. doi: 10.3389/fmolb.2022.975570
PMCID:
PMC9550266
AbstractArticlePDF–2.5M
5.
VCP interaction with HMGB1 promotes hepatocellular carcinoma progression by activating the PI3K/AKT/mTOR pathway
Zhangya Pu, Dan G. Duda, Yuanyuan Zhu, Siya Pei, Xiaofang Wang, Yan Huang, Panpan Yi, Zebing Huang, Fang Peng, Xingwang Hu, Xuegong Fan
J Transl Med. 2022; 20: 212. Published online 2022 May 13. doi: 10.1186/s12967-022-03416-5
PMCID:
PMC9102726
AbstractArticlePDF–15M
6.
Carboxylesterase-1 Assisted Targeting of HDAC Inhibitors to Mononuclear Myeloid Cells in Inflammatory Bowel Disease
Ahmed M I Elfiky, Mohammed Ghiboub, Andrew Y F Li Yim, Ishtu L Hageman, Jan Verhoeff, Manon de Krijger, Patricia H P van Hamersveld, Olaf Welting, Iris Admiraal, Shafaque Rahman, Juan J Garcia-Vallejo, Manon E Wildenberg, Laura Tomlinson, Richard Gregory, Inmaculada Rioja, Rab K Prinjha, Rebecca C Furze, Huw D Lewis, Palwinder K Mander, Sigrid E M Heinsbroek, Matthew J Bell, Wouter J de Jonge
J Crohns Colitis. 2022 Apr; 16(4): 668–681. Published online 2021 Oct 11. doi: 10.1093/ecco-jcc/jjab176
PMCID:
PMC9089418
AbstractArticlePDF–9.6M
7.
Adipose tissue–specific ablation of Ces1d causes metabolic dysregulation in mice
Gang Li, Xin Li, Li Yang, Shuyue Wang, Yulin Dai, Baharan Fekry, Lucas Veillon, Lin Tan, Rebecca Berdeaux, Kristin Eckel-Mahan, Philip L Lorenzi, Zhongming Zhao, Richard Lehner, Kai Sun
Life Sci Alliance. 2022 Aug; 5(8): e202101209. Published online 2022 Apr 22. doi: 10.26508/lsa.202101209
PMCID:
PMC9034061
AbstractArticlePDF–4.7M
8.
Transcriptional Regulation of Carboxylesterase 1 in Human Liver: Role of the Nuclear Receptor Subfamily 1 Group H Member 3 and Its Splice Isoforms
Joseph M. Collins, Rong Lu, Xinwen Wang, Hao-Jie Zhu, Danxin Wang
Drug Metab Dispos. 2022 Jan; 50(1): 43–48. Published online 2022 Jan. doi: 10.1124/dmd.121.000649
PMCID:
PMC8969197
AbstractArticlePDF–686K
9.
Copy number variation in the CES1 gene and the risk of non-alcoholic fatty liver in a Chinese Han population
Bing bing Chen, Jian hui Yan, Jing Zheng, He wei Peng, Xiao ling Cai, Xin ting Pan, Hui quan Li, Qi zhu Hong, Xian-E Peng
Sci Rep. 2021; 11: 13984. Published online 2021 Jul 7. doi: 10.1038/s41598-021-93549-2
Correction in:
Sci Rep. 2022; 12: 9242.
PMCID:
PMC8263572
AbstractArticlePDF–1.1M
10.
Melatonin inhibits lipid accumulation to repress prostate cancer progression by mediating the epigenetic modification of CES1
Lijie Zhou, Cai Zhang, Xiong Yang, Lilong Liu, Junyi Hu, Yaxin Hou, Hong Tao, Haruhiko Sugimura, Zhaohui Chen, Liang Wang, Ke Chen
Clin Transl Med. 2021 Jun; 11(6): e449. Published online 2021 Jun 6. doi: 10.1002/ctm2.449
PMCID:
PMC8181204
AbstractArticlePDF–6.0M
11.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
12.
Enhanced triacylglycerol catabolism by carboxylesterase 1 promotes aggressive colorectal carcinoma
Daria Capece, Daniel D’Andrea, Federica Begalli, Laura Goracci, Laura Tornatore, James L. Alexander, Alessandra Di Veroli, Shi-Chi Leow, Thamil S. Vaiyapuri, James K. Ellis, Daniela Verzella, Jason Bennett, Luca Savino, Yue Ma, James S. McKenzie, Maria Luisa Doria, Sam E. Mason, Kern Rei Chng, Hector C. Keun, Gary Frost, Vinay Tergaonkar, Katarzyna Broniowska, Walter Stunkel, Zoltan Takats, James M. Kinross, Gabriele Cruciani, Guido Franzoso
J Clin Invest. 2021 Jun 1; 131(11): e137845. Published online 2021 Jun 1. doi: 10.1172/JCI137845
PMCID:
PMC8159693
AbstractArticlePDF–7.6M
13.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
14.
Carboxylesterase 1 and Precision Pharmacotherapy: Pharmacogenetics and Nongenetic Regulators
Lucy Her, Hao-Jie Zhu
Drug Metab Dispos. 2020 Mar; 48(3): 230–244. Published online 2020 Mar. doi: 10.1124/dmd.119.089680
Correction in:
Drug Metab Dispos. 2020 Nov; 48(11): 1246.
PMCID:
PMC7031766
AbstractArticlePDF–770K
15.
Catalytic Hydrolysis Mechanism of Cocaine by Human Carboxylesterase 1: An Orthoester Intermediate Slows Down the Reaction
Maocai Yan, Zhen Zhang, Zhaoming Liu, Chunyan Zhang, Jingchang Zhang, Shuai Fan, Zhaoyong Yang
Molecules. 2019 Nov; 24(22): 4057. Published online 2019 Nov 9. doi: 10.3390/molecules24224057
PMCID:
PMC6891567
AbstractArticlePDF–1.6M
16.
A Dysregulation in CES1, APOE and Other Lipid Metabolism-Related Genes Is Associated to Cardiovascular Risk Factors Linked to Obesity
M. Pilar Marrades, Pedro González-Muniesa, J. Alfredo Martínez, María J. Moreno-Aliaga
Obes Facts. 2010 Oct; 3(5): 312–318. Published online 2010 Oct 15. doi: 10.1159/000321451
PMCID:
PMC6452131
AbstractArticlePDF–350K
17.
CES1 genetic variation affects the activation of angiotensin-converting enzyme inhibitors
Xinwen Wang, Guangji Wang, Jian Shi, Jiye Aa, Rinelly Comas, Yan Liang, Hao-Jie Zhu
Pharmacogenomics J. Author manuscript; available in PMC 2019 Jan 11.
Published in final edited form as: Pharmacogenomics J. 2016 Jun; 16(3): 220–230. Published online 2015 Jun 16. doi: 10.1038/tpj.2015.42
PMCID:
PMC6329299
AbstractArticlePDF–1.8M
18.
Silencing Carboxylesterase 1 in Human THP-1 Macrophages Perturbs Genes Regulated by PPARγ/RXR and RAR/RXR: Downregulation of CYP27A1-LXRα Signaling
Lee C. Mangum, Xiang Hou, Abdolsamad Borazjani, Jung Hwa Lee, Matthew K. Ross, J. Allen Crow
Biochem J. Author manuscript; available in PMC 2019 Feb 9.
Published in final edited form as: Biochem J. 2018 Feb 9; 475(3): 621–642. Published online 2018 Feb 9. doi: 10.1042/BCJ20180008
PMCID:
PMC6159944
AbstractArticlePDF–2.6M
19.
A Comprehensive Functional Assessment of Carboxylesterase 1 Nonsynonymous Polymorphisms
Xinwen Wang, Nada Rida, Jian Shi, Audrey H. Wu, Barry E. Bleske, Hao-Jie Zhu
Drug Metab Dispos. 2017 Nov; 45(11): 1149–1155. Published online 2017 Nov. doi: 10.1124/dmd.117.077669
PMCID:
PMC5637814
AbstractArticlePDF–549K
20.
Reduced carboxylesterase 1 is associated with endothelial injury in methamphetamine-induced pulmonary arterial hypertension
Mark E. Orcholski, Artyom Khurshudyan, Elya A. Shamskhou, Ke Yuan, Ian Y. Chen, Sean D. Kodani, Christophe Morisseau, Bruce D. Hammock, Ellen M. Hong, Ludmila Alexandrova, Tero-Pekka Alastalo, Gerald Berry, Roham T. Zamanian, Vinicio A. de Jesus Perez
Am J Physiol Lung Cell Mol Physiol. 2017 Aug 1; 313(2): L252–L266. Published online 2017 May 4. doi: 10.1152/ajplung.00453.2016
PMCID:
PMC5582936
AbstractArticle

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