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Items: 1 to 20 of 41

1.
Inhibition of HDAC8 Reduces the Proliferation of Adult Neural Stem Cells in the Subventricular Zone
Momoko Fukuda, Yuki Fujita, Yuko Hino, Mitsuyoshi Nakao, Katsuhiko Shirahige, Toshihide Yamashita
Int J Mol Sci. 2024 Mar; 25(5): 2540. Published online 2024 Feb 22. doi: 10.3390/ijms25052540
PMCID:
PMC10932134
AbstractArticlePDF–5.0M
2.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
3.
Hepatocyte-specific HDAC3 ablation promotes hepatocellular carcinoma in females by suppressing Foxa1/2
Yahong Xu, Yongjie Zhu, Zhenru Wu, Shengfu Li, Mingyang Shao, Qing Tao, Qing Xu, Yuwei Chen, Yuke Shu, Menglin Chen, Yongjie Zhou, Yujun Shi
BMC Cancer. 2023; 23: 906. Published online 2023 Sep 26. doi: 10.1186/s12885-023-11393-1
PMCID:
PMC10521566
AbstractArticlePDF–11M
4.
USP7 represses lineage differentiation genes in mouse embryonic stem cells by both catalytic and noncatalytic activities
Chao Liu, Lingang Sun, Yijun Tan, Qi Wang, Tao Luo, Chenlu Li, Nan Yao, Yuting Xie, Xiao Yi, Yi Zhu, Tiannan Guo, Junfeng Ji
Sci Adv. 2023 May; 9(20): eade3888. Published online 2023 May 17. doi: 10.1126/sciadv.ade3888
PMCID:
PMC10191441
AbstractArticlePDF–2.4M
5.
Histone deacetylase 8 inhibition prevents the progression of peritoneal fibrosis by counteracting the epithelial-mesenchymal transition and blockade of M2 macrophage polarization
Xun Zhou, Hui Chen, Yingfeng Shi, Jinqing Li, Xiaoyan Ma, Lin Du, Yan Hu, Min Tao, Qin Zhong, Danying Yan, Shougang Zhuang, Na Liu
Front Immunol. 2023; 14: 1137332. Published online 2023 Feb 23. doi: 10.3389/fimmu.2023.1137332
PMCID:
PMC9995794
AbstractArticlePDF–17M
6.
Histone deacetylase 8 regulates NF-κB-related inflammation in asthmatic mice through H3K9 acetylation
Yuan Ren, Menglu Li, Shiyao Bai, Xinming Su
Chin Med J (Engl) 2022 Sep 5; 135(17): 2110–2112. Published online 2022 Feb 16. doi: 10.1097/CM9.0000000000001963
PMCID:
PMC9746775
ArticlePDF–1.5M
7.
O-fucosylation of thrombospondin type 1 repeats is essential for ECM remodeling and signaling during bone development
Sanjiv Neupane, Steven J. Berardinelli, Daniel C. Cameron, Richard C. Grady, David E. Komatsu, Christopher J. Percival, Megumi Takeuchi, Atsuko Ito, Ta-Wei Liu, Alison V. Nairn, Kelley W. Moremen, Robert S. Haltiwanger, Bernadette C. Holdener
Matrix Biol. Author manuscript; available in PMC 2022 Oct 27.
Published in final edited form as: Matrix Biol. 2022 Mar; 107: 77–96. Published online 2022 Feb 12. doi: 10.1016/j.matbio.2022.02.002
PMCID:
PMC9606722
AbstractArticlePDF–6.7M
8.
Histone‐deacetylase 8 drives the immune response and the growth of glioma
Alessandro Mormino, Germana Cocozza, Giulia Fontemaggi, Sergio Valente, Vincenzo Esposito, Antonio Santoro, Giovanni Bernardini, Angela Santoni, Francesco Fazi, Antonello Mai, Cristina Limatola, Stefano Garofalo
Glia. 2021 Nov; 69(11): 2682–2698. Published online 2021 Jul 26. doi: 10.1002/glia.24065
PMCID:
PMC8457175
AbstractArticlePDF–4.9M
9.
H3 acetylation selectively promotes basal progenitor proliferation and neocortex expansion
Cemil Kerimoglu, Linh Pham, Anton B. Tonchev, M. Sadman Sakib, Yuanbin Xie, Godwin Sokpor, Pauline Antonie Ulmke, Lalit Kaurani, Eman Abbas, Huong Nguyen, Joachim Rosenbusch, Alexandra Michurina, Vincenzo Capece, Meglena Angelova, Nenad Maricic, Beate Brand-Saberi, Miriam Esgleas, Mareike Albert, Radoslav Minkov, Emil Kovachev, Ulrike Teichmann, Rho H. Seong, Wieland B. Huttner, Huu Phuc Nguyen, Anastassia Stoykova, Jochen F. Staiger, Andre Fischer, Tran Tuoc
Sci Adv. 2021 Sep; 7(38): eabc6792. Published online 2021 Sep 15. doi: 10.1126/sciadv.abc6792
PMCID:
PMC8443185
AbstractArticlePDF–11M
10.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
11.
Molecular Profiling Reveals Involvement of ESCO2 in Intermediate Progenitor Cell Maintenance in the Developing Mouse Cortex
Pauline Antonie Ulmke, M. Sadman Sakib, Peter Ditte, Godwin Sokpor, Cemil Kerimoglu, Linh Pham, Yuanbin Xie, Xiaoyi Mao, Joachim Rosenbusch, Ulrike Teichmann, Huu Phuc Nguyen, Andre Fischer, Gregor Eichele, Jochen F. Staiger, Tran Tuoc
Stem Cell Reports. 2021 Apr 13; 16(4): 968–984. Published online 2021 Apr 1. doi: 10.1016/j.stemcr.2021.03.008
PMCID:
PMC8072132
AbstractArticlePDF–8.1M
12.
Identification of histone deacetylase 8 as a novel therapeutic target for renal fibrosis
Yunhe Zhang, Jianan Zou, Evelyn Tolbert, Ting C. Zhao, George Bayliss, Shougang Zhuang
FASEB J. Author manuscript; available in PMC 2020 Aug 25.
Published in final edited form as: FASEB J. 2020 Jun; 34(6): 7295–7310. Published online 2020 Apr 12. doi: 10.1096/fj.201903254R
PMCID:
PMC7445474
AbstractArticlePDF–2.5M
13.
HDAC3 deficiency promotes liver cancer through a defect in H3K9ac/H3K9me3 transition
Hongjie Ji, Yongjie Zhou, Xiang Zhuang, Yongjie Zhu, Zhenru Wu, Yanrong Lu, Shengfu Li, Yong Zeng, Qing R. Lu, Yanying Huo, Yujun Shi, Hong Bu
Cancer Res. Author manuscript; available in PMC 2019 Aug 4.
Published in final edited form as: Cancer Res. 2019 Jul 15; 79(14): 3676–3688. Published online 2019 May 16. doi: 10.1158/0008-5472.CAN-18-3767
Correction in:
Cancer Res. 2020 Feb 15; 80(4): 923.
PMCID:
PMC6679938
AbstractArticlePDF–3.3M
14.
Mouse screen reveals multiple new genes underlying mouse and human hearing loss
Neil J. Ingham, Selina A. Pearson, Valerie E. Vancollie, Victoria Rook, Morag A. Lewis, Jing Chen, Annalisa Buniello, Elisa Martelletti, Lorenzo Preite, Chi Chung Lam, Felix D. Weiss, Zӧe Powis, Pim Suwannarat, Christopher J. Lelliott, Sally J. Dawson, Jacqueline K. White, Karen P. Steel
PLoS Biol. 2019 Apr; 17(4): e3000194. Published online 2019 Apr 11. doi: 10.1371/journal.pbio.3000194
PMCID:
PMC6459510
AbstractArticlePDF–5.1M
15.
The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1
Gina E. Elsen, Francesco Bedogni, Rebecca D. Hodge, Theo K. Bammler, James W. MacDonald, Susan Lindtner, John L. R. Rubenstein, Robert F. Hevner
Front Neurosci. 2018; 12: 571. Published online 2018 Aug 22. doi: 10.3389/fnins.2018.00571
PMCID:
PMC6113890
AbstractArticlePDF–4.8M
16.
HDAC8 regulates long-term hematopoietic stem-cell maintenance under stress by modulating p53 activity
Wei-Kai Hua, Jing Qi, Qi Cai, Emily Carnahan, Maria Ayala Ramirez, Ling Li, Guido Marcucci, Ya-Huei Kuo
Blood. 2017 Dec 14; 130(24): 2619–2630. Prepublished online 2017 Oct 30. doi: 10.1182/blood-2017-03-771386
PMCID:
PMC5731083
AbstractArticle
17.
An Acetylation Switch Modulates the Transcriptional Activity of Estrogen-Related Receptor α
Brian J. Wilson, Annie M. Tremblay, Geneviève Deblois, Guillaume Sylvain-Drolet, Vincent Giguère
Mol Endocrinol. July 1, 2010; 24(7): 1349–1358. doi: 10.1210/me.2009-0441
PMCID:
PMC5417470
AbstractArticle
18.
Inhibition of Interleukin 1β (IL-1β) Expression by Anthrax Lethal Toxin (LeTx) Is Reversed by Histone Deacetylase 8 (HDAC8) Inhibition in Murine Macrophages
Soon-Duck Ha, Chantelle Reid, Shahab Meshkibaf, Sung Ouk Kim
J Biol Chem. 2016 Apr 15; 291(16): 8745–8755. Published online 2016 Feb 24. doi: 10.1074/jbc.M115.695809
Correction in:
J Biol Chem. 2016 Oct 28; 291(44): 23363.
PMCID:
PMC4861443
AbstractArticlePDF–2.6M
19.
Hdac3 Interaction with p300 Histone Acetyltransferase Regulates the Oligodendrocyte and Astrocyte Lineage Fate Switch
Liguo Zhang, Xuelian He, Lei Liu, Minqing Jiang, Chuntao Zhao, Haibo Wang, Danyang He, Tao Zheng, Xianyao Zhou, Aishlin Hassan, Zhixing Ma, Mei Xin, Zheng Sun, Mitchell A. Lazar, Steven A. Goldman, Eric N. Olson, Q. Richard Lu
Dev Cell. Author manuscript; available in PMC 2017 Feb 8.
Published in final edited form as: Dev Cell. 2016 Feb 8; 36(3): 316–330. doi: 10.1016/j.devcel.2016.01.002
PMCID:
PMC4750051
AbstractArticlePDF–3.1M
20.
HDAC8 Inhibition Specifically Targets Inv(16) Acute Myeloid Leukemic Stem Cells by Restoring p53 Acetylation
Jing Qi, Sandeep Singh, Wei-Kai Hua, Qi Cai, Shi-Wei Chao, Ling Li, Hongjun Liu, Yinwei Ho, Tinisha McDonald, Allen Lin, Guido Marcucci, Ravi Bhatia, Wei-Jan Huang, Chung-I Chang, Ya-Huei Kuo
Cell Stem Cell. Author manuscript; available in PMC 2016 Nov 5.
Published in final edited form as: Cell Stem Cell. 2015 Nov 5; 17(5): 597–610. Published online 2015 Sep 18. doi: 10.1016/j.stem.2015.08.004
PMCID:
PMC4636961
AbstractArticlePDF–2.7M

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