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Items: 1 to 20 of 350

1.
Lhx2 promotes axon regeneration of adult retinal ganglion cells and rescues neurodegeneration in mouse models of glaucoma
Chang-Ping Li, Shen Wu, Yong-Quan Sun, Xue-Qi Peng, Maolei Gong, Hong-Zhen Du, Jingxue Zhang, Zhao-Qian Teng, Ningli Wang, Chang-Mei Liu
Cell Rep Med. 2024 May 21; 5(5): 101554. Published online 2024 May 9. doi: 10.1016/j.xcrm.2024.101554
PMCID:
PMC11148806
AbstractArticlePDF–6.6M
2.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
3.
Dbx1 is a dorsal midbrain-specific determinant of GABAergic neuron fate and regulates differentiation of the dorsal midbrain into the inferior and superior colliculi
Hong-Nhung Tran, Quy-Hoai Nguyen, Yongsu Jeong
Front Cell Dev Biol. 2024; 12: 1336308. Published online 2024 Jan 26. doi: 10.3389/fcell.2024.1336308
PMCID:
PMC10853453
AbstractArticlePDF–8.4M
4.
DOT1L deletion impairs the development of cortical parvalbumin-expressing interneurons
Arquimedes Cheffer, Marta Garcia-Miralles, Esther Maier, Ipek Akol, Henriette Franz, Vandana Shree Vedartham Srinivasan, Tanja Vogel
Cereb Cortex. 2023 Oct 1; 33(19): 10272–10285. Published online 2023 Aug 11. doi: 10.1093/cercor/bhad281
PMCID:
PMC10545437
AbstractArticlePDF–2.8M
5.
Regulation of chromatin accessibility and gene expression in the developing hippocampal primordium by LIM-HD transcription factor LHX2
Varun Suresh, Bhavana Muralidharan, Saurabh J. Pradhan, Mahima Bose, Leora D’Souza, Arpan Parichha, Puli Chandramouli Reddy, Sanjeev Galande, Shubha Tole
PLoS Genet. 2023 Aug; 19(8): e1010874. Published online 2023 Aug 18. doi: 10.1371/journal.pgen.1010874
PMCID:
PMC10482279
AbstractArticlePDF–4.4M
6.
Three-dimensional molecular architecture of mouse organogenesis
Fangfang Qu, Wenjia Li, Jian Xu, Ruifang Zhang, Jincan Ke, Xiaodie Ren, Xiaogao Meng, Lexin Qin, Jingna Zhang, Fangru Lu, Xin Zhou, Xi Luo, Zhen Zhang, Minhan Wang, Guangming Wu, Duanqing Pei, Jiekai Chen, Guizhong Cui, Shengbao Suo, Guangdun Peng
Nat Commun. 2023; 14: 4599. Published online 2023 Jul 31. doi: 10.1038/s41467-023-40155-7
PMCID:
PMC10390492
AbstractArticlePDF–13M
7.
Lactate-dependent transcriptional regulation controls mammalian eye morphogenesis
Nozomu Takata, Jason M. Miska, Marc A. Morgan, Priyam Patel, Leah K. Billingham, Neha Joshi, Matthew J. Schipma, Zachary J. Dumar, Nikita R. Joshi, Alexander V. Misharin, Ryan B. Embry, Luciano Fiore, Peng Gao, Lauren P. Diebold, Gregory S. McElroy, Ali Shilatifard, Navdeep S. Chandel, Guillermo Oliver
Nat Commun. 2023; 14: 4129. Published online 2023 Jul 14. doi: 10.1038/s41467-023-39672-2
PMCID:
PMC10349100
AbstractArticlePDF–7.7M
8.
The Midbrain Preisthmus: A Poorly Known Effect of the Isthmic Organizer
Luis Puelles, Matias Hidalgo-Sánchez
Int J Mol Sci. 2023 Jun; 24(11): 9769. Published online 2023 Jun 5. doi: 10.3390/ijms24119769
PMCID:
PMC10253667
AbstractArticlePDF–6.8M
9.
The exon junction complex component EIF4A3 is essential for mouse and human cortical progenitor mitosis and neurogenesis
Bianca M. Lupan, Rachel A. Solecki, Camila M. Musso, Fernando C. Alsina, Debra L. Silver
Development. 2023 May 15; 150(10): dev201619. Published online 2023 May 26. doi: 10.1242/dev.201619
PMCID:
PMC10233715
AbstractArticle
10.
Jarid2 promotes temporal progression of retinal progenitors via repression of Foxp1
Jianmin Zhang, Jacqueline M. Roberts, Fei Chang, Joon Schwakopf, Monica L. Vetter
Cell Rep. Author manuscript; available in PMC 2023 May 25.
Published in final edited form as: Cell Rep. 2023 Mar 28; 42(3): 112237. Published online 2023 Mar 14. doi: 10.1016/j.celrep.2023.112237
Correction in:
Cell Rep. 2023 Apr 25; 42(4): 112416.
PMCID:
PMC10210259
AbstractArticlePDF–4.4M
11.
Pyramidal neurons form active, transient, multilayered circuits perturbed by autism-associated mutations at the inception of neocortex
Martin Munz, Arjun Bharioke, Georg Kosche, Verónica Moreno-Juan, Alexandra Brignall, Tiago M. Rodrigues, Alexandra Graff-Meyer, Talia Ulmer, Stephanie Haeuselmann, Dinko Pavlinic, Nicole Ledergerber, Brigitte Gross-Scherf, Balázs Rózsa, Jacek Krol, Simone Picelli, Cameron S. Cowan, Botond Roska
Cell. 2023 Apr 27; 186(9): 1930–1949.e31. doi: 10.1016/j.cell.2023.03.025
PMCID:
PMC10156177
AbstractArticle
12.
Chromatin Remodeling Enzyme Snf2h Is Essential for Retinal Cell Proliferation and Photoreceptor Maintenance
Andrea Kuzelova, Naoko Dupacova, Barbora Antosova, Sweetu Susan Sunny, Zbynek Kozmik, Jr., Jan Paces, Arthur I. Skoultchi, Tomas Stopka, Zbynek Kozmik
Cells. 2023 Apr; 12(7): 1035. Published online 2023 Mar 28. doi: 10.3390/cells12071035
PMCID:
PMC10093269
AbstractArticlePDF–21M
13.
Visuomotor anomalies in achiasmatic mice expressing a transfer-defective Vax1 mutant
Kwang Wook Min, Namsuk Kim, Jae Hoon Lee, Younghoon Sung, Museong Kim, Eun Jung Lee, Jong-Myeong Kim, Jae-Hyun Kim, Jaeyoung Lee, Wonjin Cho, Jee Myung Yang, Nury Kim, Jaehoon Kim, C. Justin Lee, Young-Gyun Park, Seung-Hee Lee, Han-Woong Lee, Jin Woo Kim
Exp Mol Med. 2023 Feb; 55(2): 385–400. Published online 2023 Feb 3. doi: 10.1038/s12276-023-00930-4
PMCID:
PMC9981622
AbstractArticlePDF–7.4M
14.
Opposing Roles of Hepatic Stellate Cell Subpopulations in Hepatocarcinogenesis
Aveline Filliol, Yoshinobu Saito, Ajay Nair, Dianne H. Dapito, Le-Xing Yu, Aashreya Ravichandra, Sonakshi Bhattacharjee, Silvia Affo, Naoto Fujiwara, Hua Su, Qiuyan Sun, Thomas M Savage, John R Wilson-Kanamori, Jorge M Caviglia, LiKang Chin, Dongning Chen, Xiaobo Wang, Stefano Caruso, Jin Ku Kang, Amit Dipak Amin, Sebastian Wallace, Ross Dobie, Deqi Yin, Oscar M Rodriguez-Fiallos, Chuan Yin, Adam Mehal, Benjamin Izar, Richard A. Friedman, Rebecca G. Wells, Utpal B. Pajvani, Yujin Hoshida, Helen E. Remotti, Nicholas Arpaia, Jessica Zucman-Rossi, Michael Karin, Neil C Henderson, Ira Tabas, Robert F. Schwabe
Nature. Author manuscript; available in PMC 2023 Apr 5.
Published in final edited form as: Nature. 2022 Oct; 610(7931): 356–365. Published online 2022 Oct 5. doi: 10.1038/s41586-022-05289-6
PMCID:
PMC9949942
AbstractArticlePDF–10M
15.
Developmental trajectories of thalamic progenitors revealed by single-cell transcriptome profiling and Shh perturbation
Kiya W. Govek, Sixing Chen, Paraskevi Sgourdou, Yao Yao, Steven Woodhouse, Tingfang Chen, Marc V. Fuccillo, Douglas J. Epstein, Pablo G. Camara
Cell Rep. Author manuscript; available in PMC 2023 Jan 27.
Published in final edited form as: Cell Rep. 2022 Dec 6; 41(10): 111768. doi: 10.1016/j.celrep.2022.111768
PMCID:
PMC9880597
AbstractArticlePDF–2.4M
16.
Heterozygous variants in SIX3 and POU1F1 cause pituitary hormone deficiency in mouse and man
Hironori Bando, Michelle L Brinkmeier, Frederic Castinetti, Qing Fang, Mi-Sun Lee, Alexandru Saveanu, Frédérique Albarel, Clémentine Dupuis, Thierry Brue, Sally A Camper
Hum Mol Genet. 2023 Feb 1; 32(3): 367–385. Published online 2022 Aug 11. doi: 10.1093/hmg/ddac192
PMCID:
PMC9851746
AbstractArticlePDF–3.5M
17.
The LHX2-OTX2 transcriptional regulatory module controls retinal pigmented epithelium differentiation and underlies genetic risk for age-related macular degeneration
Mazal Cohen-Gulkar, Ahuvit David, Naama Messika-Gold, Mai Eshel, Shai Ovadia, Nitay Zuk-Bar, Maria Idelson, Yamit Cohen-Tayar, Benjamin Reubinoff, Tamar Ziv, Meir Shamay, Ran Elkon, Ruth Ashery-Padan
PLoS Biol. 2023 Jan; 21(1): e3001924. Published online 2023 Jan 17. doi: 10.1371/journal.pbio.3001924
PMCID:
PMC9844853
AbstractArticlePDF–2.8M
18.
DNA dioxygenases Tet2/3 regulate gene promoter accessibility and chromatin topology in lineage-specific loci to control epithelial differentiation
Guo-Dong Chen, Iqra Fatima, Qin Xu, Elena Rozhkova, Michael Y. Fessing, Andrei N. Mardaryev, Andrey A. Sharov, Guo-Liang Xu, Vladimir A. Botchkarev
Sci Adv. 2023 Jan; 9(2): eabo7605. Published online 2023 Jan 11. doi: 10.1126/sciadv.abo7605
PMCID:
PMC9833667
AbstractArticlePDF–3.1M
19.
Lhx2 is a progenitor-intrinsic modulator of Sonic Hedgehog signaling during early retinal neurogenesis
Xiaodong Li, Patrick J Gordon, John A Gaynes, Alexandra W Fuller, Randy Ringuette, Clayton P Santiago, Valerie Wallace, Seth Blackshaw, Pulin Li, Edward M Levine
eLife. 2022; 11: e78342. Published online 2022 Dec 2. doi: 10.7554/eLife.78342
PMCID:
PMC9718532
AbstractArticlePDF–14M
20.
Cbln1 regulates axon growth and guidance in multiple neural regions
Peng Han, Yuanchu She, Zhuoxuan Yang, Mengru Zhuang, Qingjun Wang, Xiaopeng Luo, Chaoqun Yin, Junda Zhu, Samie R. Jaffrey, Sheng-Jian Ji
PLoS Biol. 2022 Nov; 20(11): e3001853. Published online 2022 Nov 17. doi: 10.1371/journal.pbio.3001853
PMCID:
PMC9671368
AbstractArticlePDF–6.3M

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