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Items: 1 to 20 of 23

1.
PNPLA3 is a triglyceride lipase that mobilizes polyunsaturated fatty acids to facilitate hepatic secretion of large-sized very low-density lipoprotein
Scott M. Johnson, Hanmei Bao, Cailin E. McMahon, Yongbin Chen, Stephanie D. Burr, Aaron M. Anderson, Katja Madeyski-Bengtson, Daniel Lindén, Xianlin Han, Jun Liu
Nat Commun. 2024; 15: 4847. Published online 2024 Jun 6. doi: 10.1038/s41467-024-49224-x
PMCID:
PMC11156938
AbstractArticlePDF–3.4M
2.
Absence of Adiponutrin (PNPLA3) and Monoacylglycerol Lipase Synergistically Increases Weight Gain and Aggravates Steatohepatitis in Mice
Matteo Tardelli, Francesca V. Bruschi, Claudia D. Fuchs, Thierry Claudel, Nicole Auer, Victoria Kunczer, Onne A. H. O. Ronda, Henkjan J. Verkade, Tatjana Stojakovic, Hubert Scharnagl, Michael Trauner
Int J Mol Sci. 2021 Feb; 22(4): 2126. Published online 2021 Feb 20. doi: 10.3390/ijms22042126
PMCID:
PMC7924608
AbstractArticlePDF–3.4M
3.
Identification of Phf16 and Pnpla3 as new adipogenic factors regulated by phytochemicals
Seo-Hyuk Chang, Ui Jeong Yun, Jin Hee Choi, Suji Kim, A Reum Lee, Dong Ho Lee, Min-Ju Seo, Vanja Panic, Claudio J. Villanueva, No-Joon Song, Kye Won Park
J Cell Biochem. Author manuscript; available in PMC 2019 Aug 9.
Published in final edited form as: J Cell Biochem. 2019 Mar; 120(3): 3599–3610. Published online 2018 Sep 11. doi: 10.1002/jcb.27637
PMCID:
PMC6688606
AbstractArticlePDF–1.4M
4.
Accumulation of PNPLA3 on lipid droplets is the basis of associated hepatic steatosis
Soumik BasuRay, Yang Wang, Eriks Smagris, Jonathan C. Cohen, Helen H. Hobbs
Proc Natl Acad Sci U S A. 2019 May 7; 116(19): 9521–9526. Published online 2019 Apr 24. doi: 10.1073/pnas.1901974116
PMCID:
PMC6511016
AbstractArticlePDF–1.0M
5.
Pnpla3 silencing with antisense oligonucleotides ameliorates nonalcoholic steatohepatitis and fibrosis in Pnpla3 I148M knock-in mice
Daniel Lindén, Andrea Ahnmark, Piero Pingitore, Ester Ciociola, Ingela Ahlstedt, Anne-Christine Andréasson, Kavitha Sasidharan, Katja Madeyski-Bengtson, Magdalena Zurek, Rosellina M. Mancina, Anna Lindblom, Mikael Bjursell, Gerhard Böttcher, Marcus Ståhlman, Mohammad Bohlooly-Y, William G. Haynes, Björn Carlsson, Mark Graham, Richard Lee, Sue Murray, Luca Valenti, Sanjay Bhanot, Peter Åkerblad, Stefano Romeo
Mol Metab. 2019 Apr; 22: 49–61. Published online 2019 Feb 5. doi: 10.1016/j.molmet.2019.01.013
PMCID:
PMC6437635
AbstractArticlePDF–3.8M
6.
Patatin-like phospholipase domain–containing protein 3 promotes transfers of essential fatty acids from triglycerides to phospholipids in hepatic lipid droplets
Matthew A. Mitsche, Helen H. Hobbs, Jonathan C. Cohen
J Biol Chem. 2018 May 4; 293(18): 6958–6968. Published online 2018 Mar 19. doi: 10.1074/jbc.RA118.002333
Correction in:
J Biol Chem. 2018 Jun 15; 293(24): 9232.
PMCID:
PMC5936833
AbstractArticlePDF–2.1M
7.
The PNPLA3 variant associated with fatty liver disease (I148M) accumulates on lipid droplets by evading ubiquitylation
Soumik BasuRay, Eriks Smagris, Jonathan C. Cohen, Helen H. Hobbs
Hepatology. 2017 Oct; 66(4): 1111–1124. Published online 2017 Aug 26. doi: 10.1002/hep.29273
PMCID:
PMC5605398
AbstractArticlePDF–956K
8.
Binge alcohol alters PNPLA3 levels in liver through epigenetic mechanism involving histone H3 acetylation
Ricardo J. Restrepo, Robert W. Lim, Ronald J. Korthuis, Shivendra D. Shukla
Alcohol. Author manuscript; available in PMC 2017 Jul 28.
Published in final edited form as: Alcohol. 2017 May; 60: 77–82. Published online 2017 Mar 12. doi: 10.1016/j.alcohol.2017.01.009
PMCID:
PMC5533086
AbstractArticlePDF–573K
9.
Pnpla3I148M knockin mice accumulate PNPLA3 on lipid droplets and develop hepatic steatosis
Eriks Smagris, Soumik BasuRay, John Li, Yongcheng Huang, Ka-man V Lai, Jesper Gromada, Jonathan C Cohen, Helen H Hobbs
Hepatology. 2015 Jan; 61(1): 108–118. Published online 2014 Oct 1. doi: 10.1002/hep.27242
PMCID:
PMC4262735
AbstractArticlePDF–1.1M
10.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
11.
Chronic overexpression of PNPLA3I148M in mouse liver causes hepatic steatosis
John Zhong Li, Yongcheng Huang, Ruchan Karaman, Pavlina T. Ivanova, H. Alex Brown, Thomas Roddy, Jose Castro-Perez, Jonathan C. Cohen, Helen H. Hobbs
J Clin Invest. 2012 Nov 1; 122(11): 4130–4144. Published online 2012 Oct 1. doi: 10.1172/JCI65179
PMCID:
PMC3484461
AbstractArticlePDF–1.9M
12.
Adiponutrin Functions as a Nutritionally Regulated Lysophosphatidic Acid Acyltransferase
Manju Kumari, Gabriele Schoiswohl, Chandramohan Chitraju, Margret Paar, Irina Cornaciu, Ashraf Y. Rangrez, Nuttaporn Wongsiriroj, Harald M. Nagy, Pavlina T. Ivanova, Sarah A. Scott, Oskar Knittelfelder, Gerald N. Rechberger, Ruth Birner-Gruenberger, Sandra Eder, H. Alex Brown, Guenter Haemmerle, Monika Oberer, Achim Lass, Erin E. Kershaw, Robert Zimmermann, Rudolf Zechner
Cell Metab. Author manuscript; available in PMC 2013 May 2.
Published in final edited form as: Cell Metab. 2012 May 2; 15(5): 691–702. doi: 10.1016/j.cmet.2012.04.008
PMCID:
PMC3361708
AbstractArticlePDF–2.2M
13.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
14.
Pnpla3/Adiponutrin deficiency in mice does not contribute to fatty liver disease or metabolic syndrome
Mahesh K. Basantani, Mitch T. Sitnick, Lingzhi Cai, Daniel S. Brenner, Noah P. Gardner, John Zhong Li, Gabriele Schoiswohl, Kui Yang, Manju Kumari, Richard W. Gross, Rudolf Zechner, Erin E. Kershaw
J Lipid Res. 2011 Feb; 52(2): 318–329. doi: 10.1194/jlr.M011205
PMCID:
PMC3023552
AbstractArticlePDF–783K
15.
A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo
Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio
PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582
PMCID:
PMC3022534
AbstractArticlePDF–3.8M
16.
Pnpla3/adiponutrin deficiency in mice is not associated with fatty liver disease
Weiqin Chen, Benny Chang, Lan Li, Lawrence Chan
Hepatology. Author manuscript; available in PMC 2011 Sep 1.
Published in final edited form as: Hepatology. 2010 Sep; 52(3): 1134–1142. doi: 10.1002/hep.23812
Correction in:
volume 52 on page 2250
PMCID:
PMC2932863
AbstractArticlePDF–866K
17.
Adipose Triglyceride Lipase: Function, Regulation by Insulin, and Comparison With Adiponutrin
Erin E. Kershaw, Jonathan K. Hamm, Linda A.W. Verhagen, Odile Peroni, Masa Katic, Jeffrey S. Flier
Diabetes. Author manuscript; available in PMC 2010 Feb 10.
Published in final edited form as: Diabetes. 2006 Jan; 55(1): 148.
PMCID:
PMC2819178
AbstractArticlePDF–1.4M
18.
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells
Gwenn M. Hansen, Diane C. Markesich, Michael B. Burnett, Qichao Zhu, Karen M. Dionne, Lizabeth J. Richter, Richard H. Finnell, Arthur T. Sands, Brian P. Zambrowicz, Alejandro Abuin
Genome Res. 2008 Oct; 18(10): 1670–1679. doi: 10.1101/gr.078352.108
PMCID:
PMC2556270
AbstractArticlePDF–493K
19.
The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)
Genome Res. 2004 Oct; 14(10b): 2121–2127. doi: 10.1101/gr.2596504
Correction in:
Genome Res. 2006 Jun; 16(6): 804.
PMCID:
PMC528928
AbstractArticlePDF–140K
20.
RIKEN Integrated Sequence Analysis (RISA) System—384-Format Sequencing Pipeline with 384 Multicapillary Sequencer
Kazuhiro Shibata, Masayoshi Itoh, Katsunori Aizawa, Sumiharu Nagaoka, Nobuya Sasaki, Piero Carninci, Hideaki Konno, Junichi Akiyama, Katsuo Nishi, Tokuji Kitsunai, Hideo Tashiro, Mari Itoh, Noriko Sumi, Yoshiyuki Ishii, Shin Nakamura, Makoto Hazama, Tsutomu Nishine, Akira Harada, Rintaro Yamamoto, Hiroyuki Matsumoto, Sumito Sakaguchi, Takashi Ikegami, Katsuya Kashiwagi, Syuji Fujiwake, Kouji Inoue, Yoshiyuki Togawa, Masaki Izawa, Eiji Ohara, Masanori Watahiki, Yuko Yoneda, Tomokazu Ishikawa, Kaori Ozawa, Takumi Tanaka, Shuji Matsuura, Jun Kawai, Yasushi Okazaki, Masami Muramatsu, Yorinao Inoue, Akira Kira, Yoshihide Hayashizaki
Genome Res. 2000 Nov; 10(11): 1757–1771. doi: 10.1101/gr.152600
PMCID:
PMC310992
AbstractArticlePDF–3.4M

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