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Select item 111552641.

Lineage-specific intolerance to oncogenic drivers restricts histological transformation

Eric E. Gardner, Ethan M. Earlie, Kate Li, Jerin Thomas, Melissa J. Hubisz, Benjamin D. Stein, Chen Zhang, Lewis C. Cantley, Ashley M. Laughney, Harold Varmus

Science. Author manuscript; available in PMC 2024 Jun 6.

Published in final edited form as: Science. 2024 Feb 9; 383(6683): eadj1415. Published online 2024 Feb 9. doi: 10.1126/science.adj1415

PMCID:: PMC11155264

Abstract Article PDF–2.7M

Select item 110961762.

Proteostatic reactivation of the developmental transcription factor TBX3 drives BRAF/MAPK-mediated tumorigenesis

Zhenlei Zhang, Yufan Wu, Jinrong Fu, Xiujie Yu, Yang Su, Shikai Jia, Huili Cheng, Yan Shen, Xianghui He, Kai Ren, Xiangqian Zheng, Haixia Guan, Feng Rao, Li Zhao

Nat Commun. 2024; 15: 4108. Published online 2024 May 15. doi: 10.1038/s41467-024-48173-9

Correction in:: Nat Commun. 2024; 15: 4936.

PMCID:: PMC11096176

Abstract Article PDF–5.7M

Select item 110093013.

Deficiency of the HGF/Met pathway leads to thyroid dysgenesis by impeding late thyroid expansion

Ya Fang, Jia-Ping Wan, Zheng Wang, Shi-Yang Song, Cao-Xu Zhang, Liu Yang, Qian-Yue Zhang, Chen-Yan Yan, Feng-Yao Wu, Sang-Yu Lu, Feng Sun, Bing Han, Shuang-Xia Zhao, Mei Dong, Huai-Dong Song

Nat Commun. 2024; 15: 3165. Published online 2024 Apr 11. doi: 10.1038/s41467-024-47363-9

PMCID:: PMC11009301

Abstract Article PDF–12M

Select item 109727494.

A vagal reflex evoked by airway closure

Michael S. Schappe, Philip A. Brinn, Narendra R. Joshi, Rachel S. Greenberg, Soohong Min, AbdulRasheed A. Alabi, Chuchu Zhang, Stephen D. Liberles

Nature. 2024; 627(8005): 830–838. Published online 2024 Mar 6. doi: 10.1038/s41586-024-07144-2

PMCID:: PMC10972749

Abstract Article PDF–13M

Select item 108993385.

Loss of Ezh2 in the medial ganglionic eminence alters interneuron fate, cell morphology and gene expression profiles

Christopher T. Rhodes, Dhanya Asokumar, Mira Sohn, Shovan Naskar, Lielle Elisha, Parker Stevenson, Dongjin R. Lee, Yajun Zhang, Pedro P. Rocha, Ryan K. Dale, Soohyun Lee, Timothy J. Petros

Front Cell Neurosci. 2024; 18: 1334244. Published online 2024 Feb 14. doi: 10.3389/fncel.2024.1334244

PMCID:: PMC10899338

Abstract Article PDF–10M

Select item 107758906.

Alveolar epithelial progenitor cells require Nkx2-1 to maintain progenitor-specific epigenomic state during lung homeostasis and regeneration

Andrea Toth, Paranthaman Kannan, John Snowball, Matthew Kofron, Joseph A. Wayman, James P. Bridges, Emily R. Miraldi, Daniel Swarr, William J. Zacharias

Nat Commun. 2023; 14: 8452. Published online 2023 Dec 19. doi: 10.1038/s41467-023-44184-0

PMCID:: PMC10775890

Abstract Article PDF–15M

Select item 107582927.

Enhancer–promoter interactions can bypass CTCF-mediated boundaries and contribute to phenotypic robustness

Shreeta Chakraborty, Nina Kopitchinski, Zhenyu Zuo, Ariel Eraso, Parirokh Awasthi, Raj Chari, Apratim Mitra, Ian C. Tobias, Sakthi D. Moorthy, Ryan K. Dale, Jennifer A. Mitchell, Timothy J. Petros, Pedro P. Rocha

Nat Genet. Author manuscript; available in PMC 2024 Jan 1.

Published in final edited form as: Nat Genet. 2023 Feb; 55(2): 280–290. Published online 2023 Jan 30. doi: 10.1038/s41588-022-01295-6

PMCID:: PMC10758292

Abstract Article PDF–4.9M

Select item 106419868.

Borealin/CDCA8 deficiency alters thyroid development and results in papillary tumor-like structures

Hortense Didier-Mathon, Athanasia Stoupa, Dulanjalee Kariyawasam, Sonny Yde, Beatrix Cochant-Priollet, Lionel Groussin, Frédéric Sébag, Nicolas Cagnard, Patrick Nitschke, Dominique Luton, Michel Polak, Aurore Carré

Front Endocrinol (Lausanne) 2023; 14: 1286747. Published online 2023 Oct 27. doi: 10.3389/fendo.2023.1286747

PMCID:: PMC10641986

Abstract Article PDF–20M

Select item 106030709.

Antibody-directed extracellular proximity biotinylation reveals that Contactin-1 regulates axo-axonic innervation of axon initial segments

Yuki Ogawa, Brian C. Lim, Shanu George, Juan A. Oses-Prieto, Joshua M. Rasband, Yael Eshed-Eisenbach, Hamdan Hamdan, Supna Nair, Francesco Boato, Elior Peles, Alma L. Burlingame, Linda Van Aelst, Matthew N. Rasband

Nat Commun. 2023; 14: 6797. Published online 2023 Oct 26. doi: 10.1038/s41467-023-42273-8

PMCID:: PMC10603070

Abstract Article PDF–10M

Select item 1060289910.

Epigenetic reprogramming of a distal developmental enhancer cluster drives SOX2 overexpression in breast and lung adenocarcinoma

Luis E Abatti, Patricia Lado-Fernández, Linh Huynh, Manuel Collado, Michael M Hoffman, Jennifer A Mitchell

Nucleic Acids Res. 2023 Oct 27; 51(19): 10109–10131. Published online 2023 Sep 22. doi: 10.1093/nar/gkad734

PMCID:: PMC10602899

Abstract Article PDF–18M

Select item 1054548511.

DOT1L regulates lung developmental epithelial cell fate and adult alveolar stem cell differentiation after acute injury

Shanru Li, Derek Liberti, Su Zhou, Yun Ying, Jun Kong, Maria C. Basil, Fabian L. Cardenas-Diaz, Kazushige Shiraishi, Michael P. Morley, Edward E. Morrisey

Stem Cell Reports. 2023 Sep 12; 18(9): 1841–1853. Published online 2023 Aug 17. doi: 10.1016/j.stemcr.2023.07.006

PMCID:: PMC10545485

Abstract Article PDF–7.7M

Select item 1054543712.

DOT1L deletion impairs the development of cortical parvalbumin-expressing interneurons

Arquimedes Cheffer, Marta Garcia-Miralles, Esther Maier, Ipek Akol, Henriette Franz, Vandana Shree Vedartham Srinivasan, Tanja Vogel

Cereb Cortex. 2023 Oct 1; 33(19): 10272–10285. Published online 2023 Aug 11. doi: 10.1093/cercor/bhad281

PMCID:: PMC10545437

Abstract Article PDF–2.8M

Select item 1048595613.

Distinct requirements for Tcf3 and Tcf12 during oligodendrocyte development in the mouse telencephalon

Mary Jo Talley, Diana Nardini, Lisa A. Ehrman, Q. Richard Lu, Ronald R. Waclaw

Neural Dev. 2023; 18: 5. Published online 2023 Sep 8. doi: 10.1186/s13064-023-00173-z

PMCID:: PMC10485956

Abstract Article PDF–15M

Select item 1044575114.

Developmental emergence of cortical neurogliaform cell diversity

Lucia Gomez, Christelle Cadilhac, Julien Prados, Nandkishor Mule, Denis Jabaudon, Alexandre Dayer

Development. 2023 Aug 1; 150(15): dev201830. Published online 2023 Aug 1. doi: 10.1242/dev.201830

PMCID:: PMC10445751

Abstract Article

Select item 1041553415.

Regional and cell-type-specific afferent and efferent projections of the mouse claustrum

Quanxin Wang, Yun Wang, Hsien-Chi Kuo, Peng Xie, Xiuli Kuang, Karla E. Hirokawa, Maitham Naeemi, Shenqin Yao, Matt Mallory, Ben Ouellette, Phil Lesnar, Yaoyao Li, Min Ye, Chao Chen, Wei Xiong, Leila Ahmadinia, Laila El-Hifnawi, Ali Cetin, Staci A. Sorensen, Julie A. Harris, Hongkui Zeng, Christof Koch

Cell Rep. Author manuscript; available in PMC 2023 Oct 23.

Published in final edited form as: Cell Rep. 2023 Feb 28; 42(2): 112118. Published online 2023 Feb 13. doi: 10.1016/j.celrep.2023.112118

PMCID:: PMC10415534

Abstract Article PDF–3.9M

Select item 1039173116.

Tissue specificity of oncogenic BRAF targeted to lung and thyroid through a shared lineage factor

Elin Schoultz, Shawn Liang, Therese Carlsson, Stefan Filges, Anders Ståhlberg, Henrik Fagman, Clotilde Wiel, Volkan Sayin, Mikael Nilsson

iScience. 2023 Jul 21; 26(7): 107071. Published online 2023 Jun 8. doi: 10.1016/j.isci.2023.107071

PMCID:: PMC10391731

Abstract Article PDF–8.2M

Select item 1039049217.

Three-dimensional molecular architecture of mouse organogenesis

Fangfang Qu, Wenjia Li, Jian Xu, Ruifang Zhang, Jincan Ke, Xiaodie Ren, Xiaogao Meng, Lexin Qin, Jingna Zhang, Fangru Lu, Xin Zhou, Xi Luo, Zhen Zhang, Minhan Wang, Guangming Wu, Duanqing Pei, Jiekai Chen, Guizhong Cui, Shengbao Suo, Guangdun Peng

Nat Commun. 2023; 14: 4599. Published online 2023 Jul 31. doi: 10.1038/s41467-023-40155-7

PMCID:: PMC10390492

Abstract Article PDF–13M

Select item 1028154918.

Distinct hyperactive RAS/MAPK alleles converge on common GABAergic interneuron core programs

Sara J. Knowles, April M. Stafford, Tariq Zaman, Kartik Angara, Michael R. Williams, Jason M. Newbern, Daniel Vogt

Development. 2023 May 15; 150(10): dev201371. Published online 2023 May 31. doi: 10.1242/dev.201371

PMCID:: PMC10281549

Abstract Article

Select item 1026438019.

Directed differentiation of mouse pluripotent stem cells into functional lung-specific mesenchyme

Andrea B. Alber, Hector A. Marquez, Liang Ma, George Kwong, Bibek R. Thapa, Carlos Villacorta-Martin, Jonathan Lindstrom-Vautrin, Pushpinder Bawa, Feiya Wang, Yongfeng Luo, Laertis Ikonomou, Wei Shi, Darrell N. Kotton

Nat Commun. 2023; 14: 3488. Published online 2023 Jun 13. doi: 10.1038/s41467-023-39099-9

PMCID:: PMC10264380

Abstract Article PDF–5.7M

Select item 1023444320.

Niche-mediated repair of airways is directed in an occupant-dependent manner

Handeng Lyu, Rachel Warren, Shan Gao, Kylie Klinkhammer, Tingting Yuan, Jin-San Zhang, Douglas Brownfield, Xiaokun Li, Stijn P. De Langhe

Cell Rep. Author manuscript; available in PMC 2023 Jun 1.

Published in final edited form as: Cell Rep. 2022 Dec 20; 41(12): 111863. doi: 10.1016/j.celrep.2022.111863

PMCID:: PMC10234443

Abstract Article PDF–3.2M

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