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Select item 108724771.

Protein interaction network revealed by quantitative proteomic analysis links TFIIB to multiple aspects of the transcription cycle

Michael J. O’Brien, Athar Ansari

Biochim Biophys Acta Proteins Proteom. Author manuscript; available in PMC 2024 Feb 16.

Published in final edited form as: Biochim Biophys Acta Proteins Proteom. 2024 Jan 1; 1872(1): 140968. Published online 2023 Oct 19. doi: 10.1016/j.bbapap.2023.140968

PMCID:: PMC10872477

Abstract Article PDF–1.7M

Select item 107001382.

The social and structural architecture of the yeast protein interactome

André C. Michaelis, Andreas-David Brunner, Maximilian Zwiebel, Florian Meier, Maximilian T. Strauss, Isabell Bludau, Matthias Mann

Nature. 2023; 624(7990): 192–200. Published online 2023 Nov 15. doi: 10.1038/s41586-023-06739-5

PMCID:: PMC10700138

Abstract Article PDF–20M

Select item 106295573.

Regulation of replication origin licensing by ORC phosphorylation reveals a two-step mechanism for Mcm2-7 ring closing

Audra L. Amasino, Shalini Gupta, Larry J. Friedman, Jeff Gelles, Stephen P. Bell

Proc Natl Acad Sci U S A. 2023 Jul 18; 120(29): e2221484120. Published online 2023 Jul 10. doi: 10.1073/pnas.2221484120

PMCID:: PMC10629557

Abstract Article PDF–2.3M

Select item 102922104.

Nuclear pore complexes mediate subtelomeric gene silencing by regulating PCNA levels on chromatin

Sanjeev Kumar Choudhry, Maxwell L. Neal, Song Li, Arti T. Navare, Trevor Van Eeuwen, Richard W. Wozniak, Fred D. Mast, Michael P. Rout, John D. Aitchison

J Cell Biol. 2023 Sep 4; 222(9): e202207060. Published online 2023 Jun 26. doi: 10.1083/jcb.202207060

PMCID:: PMC10292210

Abstract Article PDF–5.9M

Select item 98133925.

An essential Noc3p dimerization cycle mediates ORC double-hexamer formation in replication licensing

Aftab Amin, Rentian Wu, Muhammad Ajmal Khan, Man Hei Cheung, Yanting Liang, Changdong Liu, Guang Zhu, Zhi-Ling Yu, Chun Liang

Life Sci Alliance. 2023 Mar; 6(3): e202201594. Published online 2023 Jan 4. doi: 10.26508/lsa.202201594

PMCID:: PMC9813392

Abstract Article PDF–4.3M

Select item 96296216.

Comprehensive characterization of the Hsp70 interactome reveals novel client proteins and interactions mediated by posttranslational modifications

Nitika, Bo Zheng, Linhao Ruan, Jake T. Kline, Siddhi Omkar, Jacek Sikora, Mara Texeira Torres, Yuhao Wang, Jade E. Takakuwa, Romain Huguet, Cinzia Klemm, Verónica A. Segarra, Matthew J. Winters, Peter M. Pryciak, Peter H. Thorpe, Kazuo Tatebayashi, Rong Li, Luca Fornelli, Andrew W. Truman

PLoS Biol. 2022 Oct; 20(10): e3001839. Published online 2022 Oct 21. doi: 10.1371/journal.pbio.3001839

PMCID:: PMC9629621

Abstract Article PDF–3.4M

Select item 92098117.

New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources

Stacia R Engel, Edith D Wong, Robert S Nash, Suzi Aleksander, Micheal Alexander, Eric Douglass, Kalpana Karra, Stuart R Miyasato, Matt Simison, Marek S Skrzypek, Shuai Weng, J Michael Cherry

Genetics. 2022 Apr; 220(4): iyab224. Published online 2021 Dec 13. doi: 10.1093/genetics/iyab224

PMCID:: PMC9209811

Abstract Article PDF–818K

Select item 88816118.

A mechanism of origin licensing control through autoinhibition of S. cerevisiae ORC·DNA·Cdc6

Jan Marten Schmidt, Ran Yang, Ashish Kumar, Olivia Hunker, Jan Seebacher, Franziska Bleichert

Nat Commun. 2022; 13: 1059. Published online 2022 Feb 25. doi: 10.1038/s41467-022-28695-w

PMCID:: PMC8881611

Abstract Article PDF–4.5M

Select item 88280539.

A helicase-tethered ORC flip enables bidirectional helicase loading

Shalini Gupta, Larry J Friedman, Jeff Gelles, Stephen P Bell

eLife. 2021; 10: e74282. Published online 2021 Dec 9. doi: 10.7554/eLife.74282

PMCID:: PMC8828053

Abstract Article PDF–7.0M

Select item 797972610.

Stabilisation of half MCM ring by Cdt1 during DNA insertion

Marina Guerrero-Puigdevall, Narcis Fernandez-Fuentes, Jordi Frigola

Nat Commun. 2021; 12: 1746. Published online 2021 Mar 19. doi: 10.1038/s41467-021-21932-8

PMCID:: PMC7979726

Abstract Article PDF–1.8M

Select item 744295511.

Biochemical and functional characterization of a meiosis-specific Pch2/ORC AAA+ assembly

María Ascensión Villar-Fernández, Richard Cardoso da Silva, Magdalena Firlej, Dongqing Pan, Elisabeth Weir, Annika Sarembe, Vivek B Raina, Tanja Bange, John R Weir, Gerben Vader

Life Sci Alliance. 2020 Nov; 3(11): e201900630. Published online 2020 Aug 21. doi: 10.26508/lsa.201900630

PMCID:: PMC7442955

Abstract Article PDF–3.2M

Select item 580540912.

Multiple kinases inhibit origin licensing and helicase activation to ensure reductive cell division during meiosis

David V Phizicky, Luke E Berchowitz, Stephen P Bell

eLife. 2018; 7: e33309. Published online 2018 Feb 1. doi: 10.7554/eLife.33309

PMCID:: PMC5805409

Abstract Article PDF–3.1M

Select item 576535913.

Genome-Wide Mapping of Decay Factor–mRNA Interactions in Yeast Identifies Nutrient-Responsive Transcripts as Targets of the Deadenylase Ccr4

Jason E. Miller, Liye Zhang, Haoyang Jiang, Yunfei Li, B. Franklin Pugh, Joseph C. Reese

G3 (Bethesda) 2018 Jan; 8(1): 315–330. Published online 2017 Nov 20. doi: 10.1534/g3.117.300415

PMCID:: PMC5765359

Abstract Article PDF–2.2M

Select item 566188514.

A global interaction network maps a wiring diagram of cellular function

Michael Costanzo, Benjamin VanderSluis, Elizabeth N. Koch, Anastasia Baryshnikova, Carles Pons, Guihong Tan, Wen Wang, Matej Usaj, Julia Hanchard, Susan D. Lee, Vicent Pelechano, Erin B. Styles, Maximilian Billmann, Jolanda van Leeuwen, Nydia van Dyk, Zhen-Yuan Lin, Elena Kuzmin, Justin Nelson, Jeff S. Piotrowski, Tharan Srikumar, Sondra Bahr, Yiqun Chen, Raamesh Deshpande, Christoph F. Kurat, Sheena C. Li, Zhijian Li, Mojca Mattiazzi Usaj, Hiroki Okada, Natasha Pascoe, Bryan-Joseph San Luis, Sara Sharifpoor, Emira Shuteriqi, Scott W. Simpkins, Jamie Snider, Harsha Garadi Suresh, Yizhao Tan, Hongwei Zhu, Noel Malod-Dognin, Vuk Janjic, Natasa Przulj, Olga G. Troyanskaya, Igor Stagljar, Tian Xia, Yoshikazu Ohya, Anne-Claude Gingras, Brian Raught, Michael Boutros, Lars M. Steinmetz, Claire L. Moore, Adam P. Rosebrock, Amy A. Caudy, Chad L. Myers, Brenda Andrews, Charles Boone

Science. Author manuscript; available in PMC 2017 Oct 30.

Published in final edited form as: Science. 2016 Sep 23; 353(6306): aaf1420. doi: 10.1126/science.aaf1420

PMCID:: PMC5661885

Abstract Article PDF–2.6M

Select item 565819215.

Defective replication initiation results in locus specific chromosome breakage and a ribosomal RNA deficiency in yeast

Joseph C. Sanchez, Elizabeth X. Kwan, Thomas J. Pohl, Haley M. Amemiya, M. K. Raghuraman, Bonita J. Brewer

PLoS Genet. 2017 Oct; 13(10): e1007041. Published online 2017 Oct 16. doi: 10.1371/journal.pgen.1007041

PMCID:: PMC5658192

Abstract Article PDF–6.7M

Select item 550350516.

Structural basis of MCM2-7 replicative helicase loading by ORC-Cdc6 and Cdt1

Zuanning Yuan, Alberto Riera, Lin Bai, Jingchuan Sun, Saikat Nandi, Christos Spanos, Zhuo Angel Chen, Marta Barbon, Juri Rappsilber, Bruce Stillman, Christian Speck, Huilin Li

Nat Struct Mol Biol. Author manuscript; available in PMC 2017 Aug 13.

Published in final edited form as: Nat Struct Mol Biol. 2017 Mar; 24(3): 316–324. Published online 2017 Feb 13. doi: 10.1038/nsmb.3372