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Items: 1 to 20 of 64

1.
CASZ1 upregulates PI3K-AKT-mTOR signaling and promotes T-cell acute lymphoblastic leukemia
Bruno A. Cardoso, Mafalda Duque, Ana Gírio, Rita Fragoso, Mariana L. Oliveira, James R. Allen, Leila R. Martins, Nádia C. Correia, André Bortolini Silveira, Alexandra Veloso, Shunsuke Kimura, Lisa Demoen, Filip Matthijssens, Sima Jeha, Cheng Cheng, Ching-Hon Pui, Ana R. Grosso, João L. Neto, Sérgio F. de Almeida, Pieter Van Vlieberghe, Charles G. Mullighan, J. Andres Yunes, David M. Langenau, Françoise Pflumio, João T. Barata
Haematologica. 2024 Jun 1; 109(6): 1713–1725. Published online 2023 Dec 7. doi: 10.3324/haematol.2023.282854
PMCID:
PMC11141679
AbstractArticlePDF–3.5M
2.
Constitutively active CaMKII Drives B lineage acute lymphoblastic leukemia/lymphoma in tp53 mutant zebrafish
Sarah C. Rothschild, Guanhua Lai, Robert M. Tombes, Wilson K. Clements
PLoS Genet. 2023 Dec; 19(12): e1011102. Published online 2023 Dec 20. doi: 10.1371/journal.pgen.1011102
PMCID:
PMC10766190
AbstractArticlePDF–3.6M
3.
Defining function of wild-type and three patient-specific TP53 mutations in a zebrafish model of embryonal rhabdomyosarcoma
Jiangfei Chen, Kunal Baxi, Amanda E Lipsitt, Nicole Rae Hensch, Long Wang, Prethish Sreenivas, Paulomi Modi, Xiang Ru Zhao, Antoine Baudin, Daniel G Robledo, Abhik Bandyopadhyay, Aaron Sugalski, Anil K Challa, Dias Kurmashev, Andrea R Gilbert, Gail E Tomlinson, Peter Houghton, Yidong Chen, Madeline N Hayes, Eleanor Y Chen, David S Libich, Myron S Ignatius
eLife. 2023; 12: e68221. Published online 2023 Jun 2. doi: 10.7554/eLife.68221
PMCID:
PMC10322150
AbstractArticlePDF–14M
4.
Embryonic organizer formation disorder leads to multiorgan dysplasia in Down syndrome
Yanyan Liu, Ziyuan Lin, Ying Peng, Yan Jiang, Xuan Zhang, Hongmei Zhu, Lili Zhang, Jiurong Chen, Xianghua Shu, Min Luo, Dan Xie, Yan Chen, Huijuan Liao, Mingfeng Liu, Xiaohu Zhang, Shanling Liu, He Wang, Bin Zhou, Huaqin Sun
Cell Death Dis. 2022 Dec; 13(12): 1054. Published online 2022 Dec 19. doi: 10.1038/s41419-022-05517-x
PMCID:
PMC9763398
AbstractArticlePDF–7.1M
5.
Mutant IL7R collaborates with MYC to induce T-cell acute lymphoblastic leukemia
Mariana L. Oliveira, Alexandra Veloso, Elaine G. Garcia, Sowmya Iyer, Clara Pereira, Vasco M. Barreto, David M. Langenau, João T. Barata
Leukemia. 2022; 36(6): 1533–1540. Published online 2022 May 17. doi: 10.1038/s41375-022-01590-5
PMCID:
PMC9162918
AbstractArticlePDF–2.0M
6.
IRF4 drives clonal evolution and lineage choice in a zebrafish model of T-cell lymphoma
Stella Amanda, Tze King Tan, Jolynn Zu Lin Ong, Madelaine Skolastika Theardy, Regina Wan Ju Wong, Xiao Zi Huang, Muhammad Zulfaqar Ali, Yan Li, Zhiyuan Gong, Hiroshi Inagaki, Ee Yong Foo, Brendan Pang, Soo Yong Tan, Shinsuke Iida, Takaomi Sanda
Nat Commun. 2022; 13: 2420. Published online 2022 May 3. doi: 10.1038/s41467-022-30053-9
PMCID:
PMC9065160
AbstractArticlePDF–5.1M
7.
Neutrophil-Associated Responses to Vibrio cholerae Infection in a Natural Host Model
Dustin Farr, Dhrubajyoti Nag, Walter J. Chazin, Simone Harrison, Ryan Thummel, Xixia Luo, Saumya Raychaudhuri, Jeffrey H. Withey
Infect Immun. 2022 Mar; 90(3): e00466-21. Prepublished online 2022 Jan 24. Published online 2022 Mar 17. doi: 10.1128/iai.00466-21
PMCID:
PMC8929324
AbstractArticlePDF–2.5M
8.
RAG2 abolishes RAG1 aggregation to facilitate V(D)J recombination
Tingting Gan, Yuhong Wang, Yang Liu, David G. Schatz, Jiazhi Hu
Cell Rep. Author manuscript; available in PMC 2022 Oct 12.
Published in final edited form as: Cell Rep. 2021 Oct 12; 37(2): 109824. doi: 10.1016/j.celrep.2021.109824
PMCID:
PMC8783374
AbstractArticlePDF–1.5M
9.
Synergistic melanoma cell death mediated by inhibition of both MCL1 and BCL2 in high-risk tumors driven by NF1/PTEN loss
Shuning He, Mark W. Zimmerman, Hillary M. Layden, Alla Berezovskaya, Julia Etchin, Megan W. Martel, Grace Thurston, Chang-Bin Jing, Ellen van Rooijen, Charles K. Kaufman, Scott J. Rodig, Leonard I. Zon, E. Elizabeth Patton, Marc R. Mansour, A. Thomas Look
Oncogene. 2021; 40(38): 5718–5729. Published online 2021 Jul 30. doi: 10.1038/s41388-021-01926-y
PMCID:
PMC8460449
AbstractArticlePDF–5.8M
10.
Single-cell imaging of T cell immunotherapy responses in vivo
Chuan Yan, Qiqi Yang, Songfa Zhang, David G. Millar, Eric J. Alpert, Daniel Do, Alexandra Veloso, Dalton C. Brunson, Benjamin J. Drapkin, Marcello Stanzione, Irene Scarfò, John C. Moore, Sowmya Iyer, Qian Qin, Yun Wei, Karin M. McCarthy, John F. Rawls, Nick J. Dyson, Mark Cobbold, Marcela V. Maus, David M. Langenau
J Exp Med. 2021 Oct 4; 218(10): e20210314. Published online 2021 Aug 20. doi: 10.1084/jem.20210314
PMCID:
PMC8383813
AbstractArticlePDF–7.1M
11.
Prmt5 promotes vascular morphogenesis independently of its methyltransferase activity
Aurélie Quillien, Guerric Gilbert, Manon Boulet, Séverine Ethuin, Lucas Waltzer, Laurence Vandel
PLoS Genet. 2021 Jun; 17(6): e1009641. Published online 2021 Jun 21. doi: 10.1371/journal.pgen.1009641
PMCID:
PMC8248709
AbstractArticlePDF–3.7M
12.
Oncorequisite role of an aldehyde dehydrogenase in the pathogenesis of T-cell acute lymphoblastic leukemia
Chujing Zhang, Stella Amanda, Cheng Wang, Tze King Tan, Muhammad Zulfaqar Ali, Wei Zhong Leong, Ley Moy Ng, Shojiro Kitajima, Zhenhua Li, Allen Eng Juh Yeoh, Shi Hao Tan, Takaomi Sanda
Haematologica. 2021 Jun 1; 106(6): 1545–1558. Published online 2020 May 15. doi: 10.3324/haematol.2019.245639
PMCID:
PMC8168519
AbstractArticlePDF–3.3M
13.
The multifaceted role of protein kinase CK2 in high-risk acute lymphoblastic leukemia
Yun Zhou, Haiwei Lian, Ning Shen, Sovannarith Korm, Andrew Kwok Ping Lam, Olivia Layton, Leah N. Huiting, Dun Li, Kelly Miao, Aozhuo Zeng, Esther Landesman-Bollag, David C. Seldin, Hui Fu, Li Hong, Hui Feng
Haematologica. 2021 May 1; 106(5): 1461–1465. Published online 2020 Aug 13. doi: 10.3324/haematol.2020.246918
PMCID:
PMC8094085
ArticlePDF–762K
14.
A novel TLX1-driven T-ALL zebrafish model: comparative genomic analysis with other leukemia models
Siebe Loontiens, Suzanne Vanhauwaert, Lisa Depestel, Givani Dewyn, Wouter Van Loocke, Finola E. Moore, Elaine G. Garcia, Lance Batchelor, Chiara Borga, Barbara Squiban, Megan Malone-Perez, Pieter-Jan Volders, Volodimir Olexiouk, Pieter Van Vlierberghe, David M. Langenau, J. Kimble Frazer, Kaat Durinck, Frank Speleman
Leukemia. Author manuscript; available in PMC 2021 Feb 25.
Published in final edited form as: Leukemia. 2020 Dec; 34(12): 3398–3403. Published online 2020 Jun 26. doi: 10.1038/s41375-020-0938-2
PMCID:
PMC7906429
ArticlePDF–550K
15.
Generation of foxn1/Casper Mutant Zebrafish for Allograft and Xenograft of Normal and Malignant Cells
Peng Lv, Dongyuan Ma, Shuai Gao, Yifan Zhang, Young-Ki Bae, Guixian Liang, Suwei Gao, Jung-Hwa Choi, Cheol-Hee Kim, Lu Wang, Feng Liu
Stem Cell Reports. 2020 Sep 8; 15(3): 749–760. Published online 2020 Aug 20. doi: 10.1016/j.stemcr.2020.07.020
PMCID:
PMC7486299
AbstractArticlePDF–3.2M
16.
Direct Phosphorylation and Stabilization of MYC by Aurora B Kinase Promote T-cell Leukemogenesis
Jue Jiang, Jingchao Wang, Ming Yue, Xiaolian Cai, Tianci Wang, Chao Wu, Hexiu Su, Yanwu Wang, Meng Han, Yingchi Zhang, Xiaofan Zhu, Peng Jiang, Peng Li, Yonghua Sun, Wuhan Xiao, Hui Feng, Guoliang Qing, Hudan Liu
Cancer Cell. Author manuscript; available in PMC 2021 Feb 10.
Published in final edited form as: Cancer Cell. 2020 Feb 10; 37(2): 200–215.e5. doi: 10.1016/j.ccell.2020.01.001
PMCID:
PMC7321798
AbstractArticlePDF–2.1M
17.
Role of kif2c, A Gene Related to ALL Relapse, in Embryonic Hematopoiesis in Zebrafish
Chang-Kyu Oh, Ji Wan Kang, Yoonsung Lee, Kyungjae Myung, Mihyang Ha, Junho Kang, Eun Jung Kwon, Youngjoo Kim, Sae-Ock Oh, Hye Jin Heo, Shin Kim, Yun Hak Kim
Int J Mol Sci. 2020 May; 21(9): 3127. Published online 2020 Apr 28. doi: 10.3390/ijms21093127
PMCID:
PMC7246619
AbstractArticlePDF–2.0M
18.
Parental exposure to bisphenol A and its analogs influences zebrafish offspring immunity
Xing Dong, Zhen Zhang, Shunlong Meng, Chenyuan Pan, Ming Yang, Xiangyang Wu, Liuqing Yang, Hai Xu
Sci Total Environ. 2018 Jan 1; 610: 291–297. Published online 2017 Aug 11. doi: 10.1016/j.scitotenv.2017.08.057
PMCID:
PMC7112096
AbstractArticlePDF–824K
19.
The evolution of zebrafish RAG2 protein is required for adapting to the elevated body temperature of the higher endothermic vertebrates
Ao Sun, Ke Xu, Haifeng Liu, Hua Li, Yaohuang Shi, Xiaoyan Zhu, Tao Liang, Xinyue Li, Xianxia Cao, Yanhong Ji, Taijiao Jiang, Chenqi Xu, Xiaolong Liu
Sci Rep. 2020; 10: 4126. Published online 2020 Mar 5. doi: 10.1038/s41598-020-61019-w
PMCID:
PMC7057966
AbstractArticlePDF–3.0M
20.
Protein tyrosine phosphatase 4A3 (PTP4A3/PRL-3) drives migration and progression of T-cell acute lymphoblastic leukemia in vitro and in vivo
M. Wei, M. G. Haney, D. R. Rivas, J. S. Blackburn
Oncogenesis. 2020 Jan; 9(1): 6. Published online 2020 Jan 30. doi: 10.1038/s41389-020-0192-5
PMCID:
PMC6992623
AbstractArticlePDF–2.0M

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