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Items: 1 to 20 of 48

1.
Structure-based engineering of Tor complexes reveals that two types of yeast TORC1 produce distinct phenotypes
Yoshiaki Kamada, Chiharu Umeda, Yukio Mukai, Hokuto Ohtsuka, Yoko Otsubo, Akira Yamashita, Takahiro Kosugi
J Cell Sci. 2024 Feb 15; 137(4): jcs261625. Published online 2024 Feb 28. doi: 10.1242/jcs.261625
PMCID:
PMC10941655
AbstractArticle
2.
Misregulation of cell cycle-dependent methylation of budding yeast CENP-A contributes to chromosomal instability
Prashant K. Mishra, Wei-Chun Au, Pedro G. Castineira, Nazrin Ali, John Stanton, Lars Boeckmann, Yoshimitsu Takahashi, Michael Costanzo, Charles Boone, Kerry S. Bloom, Peter H. Thorpe, Munira A. Basrai
Mol Biol Cell. 2023 Sep 1; 34(10): ar99. Published online 2023 Aug 17. doi: 10.1091/mbc.E23-03-0108
PMCID:
PMC10551700
AbstractArticlePDF–3.7M
3.
Mediator recruits the cohesin loader Scc2 to RNA Pol II-transcribed genes and promotes sister chromatid cohesion
Mark Mattingly, Chris Seidel, Sofía Muñoz, Yan Hao, Ying Zhang, Zhihui Wen, Laurence Florens, Frank Uhlmann, Jennifer L. Gerton
Curr Biol. 2022 Jul 11; 32(13): 2884–2896.e6. doi: 10.1016/j.cub.2022.05.019
PMCID:
PMC9286023
AbstractArticle
4.
New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources
Stacia R Engel, Edith D Wong, Robert S Nash, Suzi Aleksander, Micheal Alexander, Eric Douglass, Kalpana Karra, Stuart R Miyasato, Matt Simison, Marek S Skrzypek, Shuai Weng, J Michael Cherry
Genetics. 2022 Apr; 220(4): iyab224. Published online 2021 Dec 13. doi: 10.1093/genetics/iyab224
PMCID:
PMC9209811
AbstractArticlePDF–818K
5.
Comprehensive Synthetic Genetic Array Analysis of Alleles That Interact with Mutation of the Saccharomyces cerevisiae RecQ Helicases Hrq1 and Sgs1
Elsbeth Sanders, Phoebe A. Nguyen, Cody M. Rogers, Matthew L. Bochman
G3 (Bethesda) 2020 Dec; 10(12): 4359–4368. Published online 2020 Oct 28. doi: 10.1534/g3.120.401709
PMCID:
PMC7718751
AbstractArticlePDF–1.2M
6.
Systematic analysis of bypass suppression of essential genes
Jolanda van Leeuwen, Carles Pons, Guihong Tan, Zi Yang Wang, Jing Hou, Jochen Weile, Marinella Gebbia, Wendy Liang, Ermira Shuteriqi, Zhijian Li, Maykel Lopes, Matej Ušaj, Andreia Dos Santos Lopes, Natascha van Lieshout, Chad L Myers, Frederick P Roth, Patrick Aloy, Brenda J Andrews, Charles Boone
Mol Syst Biol. 2020 Sep; 16(9): e9828. Published online 2020 Sep 17. doi: 10.15252/msb.20209828
PMCID:
PMC7507402
AbstractArticlePDF–1.9M
7.
Analysis of the roles of phosphatidylinositol-4,5-bisphosphate and individual subunits in assembly, localization, and function of Saccharomyces cerevisiae target of rapamycin complex 2
Maria Nieves Martinez Marshall, Anita Emmerstorfer-Augustin, Kristin L. Leskoske, Lydia H. Zhang, Biyun Li, Jeremy Thorner
Mol Biol Cell. 2019 Jun 1; 30(12): 1555–1574. doi: 10.1091/mbc.E18-10-0682
Correction in:
Mol Biol Cell. 2019 Dec 1; 30(25): 3074.
Correction in:
Mol Biol Cell. 2022 Oct 1; 33(12): cor4.
PMCID:
PMC6724684
AbstractArticlePDF–3.1M
8.
Saccharomyces cerevisiae Gle2/Rae1 is involved in septin organization, essential for cell cycle progression
Gesa Zander, Wilfried Kramer, Anika Seel, Heike Krebber
Yeast. 2017 Nov; 34(11): 459–470. Published online 2017 Sep 28. doi: 10.1002/yea.3249
PMCID:
PMC6472880
AbstractArticlePDF–1.9M
9.
Phosphorylation by the stress-activated MAPK Slt2 down-regulates the yeast TOR complex 2
Kristin L. Leskoske, Françoise M. Roelants, Anita Emmerstorfer-Augustin, Christoph M. Augustin, Edward P. Si, Jennifer M. Hill, Jeremy Thorner
Genes Dev. 2018 Dec 1; 32(23-24): 1576–1590. doi: 10.1101/gad.318709.118
PMCID:
PMC6295167
AbstractArticlePDF–2.9M
10.
Systematic Analysis of Complex Genetic Interactions
Elena Kuzmin, Benjamin VanderSluis, Wen Wang, Guihong Tan, Raamesh Deshpande, Yiqun Chen, Matej Usaj, Attila Balint, Mojca Mattiazzi Usaj, Jolanda van Leeuwen, Elizabeth N. Koch, Carles Pons, Andrius J. Dagilis, Michael Pryszlak, Jason Zi Yang Wang, Julia Hanchard, Margot Riggi, Kaicong Xu, Hamed Heydari, Bryan-Joseph San Luis, Ermira Shuteriqi, Hongwei Zhu, Nydia Van Dyk, Sara Sharifpoor, Michael Costanzo, Robbie Loewith, Amy Caudy, Daniel Bolnick, Grant W. Brown, Brenda J. Andrews, Charles Boone, Chad L. Myers
Science. Author manuscript; available in PMC 2018 Nov 4.
Published in final edited form as: Science. 2018 Apr 20; 360(6386): eaao1729. doi: 10.1126/science.aao1729
PMCID:
PMC6215713
AbstractArticlePDF–1.9M
11.
Lateral plasma membrane compartmentalization links protein function and turnover
Jon V Busto, Annegret Elting, Daniel Haase, Felix Spira, Julian Kuhlman, Marco Schäfer‐Herte, Roland Wedlich‐Söldner
EMBO J. 2018 Aug 15; 37(16): e99473. Published online 2018 Jul 5. doi: 10.15252/embj.201899473
PMCID:
PMC6092676
AbstractArticlePDF–1.8M
12.
Redesigning TOR Kinase to Explore the Structural Basis for TORC1 and TORC2 Assembly
Andrew Hill, Brad Niles, Andrew Cuyegkeng, Ted Powers
Biomolecules. 2018 Jun; 8(2): 36. Published online 2018 Jun 1. doi: 10.3390/biom8020036
PMCID:
PMC6023025
AbstractArticlePDF–12M
13.
Heterologous mammalian Akt disrupts plasma membrane homeostasis by taking over TORC2 signaling in Saccharomyces cerevisiae
Isabel Rodríguez-Escudero, Teresa Fernández-Acero, Víctor J. Cid, María Molina
Sci Rep. 2018; 8: 7732. Published online 2018 May 16. doi: 10.1038/s41598-018-25717-w
PMCID:
PMC5955888
AbstractArticlePDF–3.0M
14.
Global analysis of genetic circuitry and adaptive mechanisms enabling resistance to the azole antifungal drugs
Harley O’Connor Mount, Nicole M. Revie, Robert T. Todd, Kaitlin Anstett, Cathy Collins, Michael Costanzo, Charles Boone, Nicole Robbins, Anna Selmecki, Leah E. Cowen
PLoS Genet. 2018 Apr; 14(4): e1007319. Published online 2018 Apr 27. doi: 10.1371/journal.pgen.1007319
PMCID:
PMC5922528
AbstractArticlePDF–7.1M
15.
Genome-Wide Mapping of Decay Factor–mRNA Interactions in Yeast Identifies Nutrient-Responsive Transcripts as Targets of the Deadenylase Ccr4
Jason E. Miller, Liye Zhang, Haoyang Jiang, Yunfei Li, B. Franklin Pugh, Joseph C. Reese
G3 (Bethesda) 2018 Jan; 8(1): 315–330. Published online 2017 Nov 20. doi: 10.1534/g3.117.300415
PMCID:
PMC5765359
AbstractArticlePDF–2.2M
16.
Cryo-EM structure of Saccharomyces cerevisiae target of rapamycin complex 2
Manikandan Karuppasamy, Beata Kusmider, Taiana M. Oliveira, Christl Gaubitz, Manoel Prouteau, Robbie Loewith, Christiane Schaffitzel
Nat Commun. 2017; 8: 1729. Published online 2017 Nov 23. doi: 10.1038/s41467-017-01862-0
PMCID:
PMC5700991
AbstractArticlePDF–2.6M
17.
A global interaction network maps a wiring diagram of cellular function
Michael Costanzo, Benjamin VanderSluis, Elizabeth N. Koch, Anastasia Baryshnikova, Carles Pons, Guihong Tan, Wen Wang, Matej Usaj, Julia Hanchard, Susan D. Lee, Vicent Pelechano, Erin B. Styles, Maximilian Billmann, Jolanda van Leeuwen, Nydia van Dyk, Zhen-Yuan Lin, Elena Kuzmin, Justin Nelson, Jeff S. Piotrowski, Tharan Srikumar, Sondra Bahr, Yiqun Chen, Raamesh Deshpande, Christoph F. Kurat, Sheena C. Li, Zhijian Li, Mojca Mattiazzi Usaj, Hiroki Okada, Natasha Pascoe, Bryan-Joseph San Luis, Sara Sharifpoor, Emira Shuteriqi, Scott W. Simpkins, Jamie Snider, Harsha Garadi Suresh, Yizhao Tan, Hongwei Zhu, Noel Malod-Dognin, Vuk Janjic, Natasa Przulj, Olga G. Troyanskaya, Igor Stagljar, Tian Xia, Yoshikazu Ohya, Anne-Claude Gingras, Brian Raught, Michael Boutros, Lars M. Steinmetz, Claire L. Moore, Adam P. Rosebrock, Amy A. Caudy, Chad L. Myers, Brenda Andrews, Charles Boone
Science. Author manuscript; available in PMC 2017 Oct 30.
Published in final edited form as: Science. 2016 Sep 23; 353(6306): aaf1420. doi: 10.1126/science.aaf1420
PMCID:
PMC5661885
AbstractArticlePDF–2.6M
18.
The Genetic Landscape of a Cell
Michael Costanzo, Anastasia Baryshnikova, Jeremy Bellay, Yungil Kim, Eric D. Spear, Carolyn S. Sevier, Huiming Ding, Judice L.Y. Koh, Kiana Toufighi, Sara Mostafavi, Jeany Prinz, Robert P. St. Onge, Benjamin VanderSluis, Taras Makhnevych, Franco J. Vizeacoumar, Solmaz Alizadeh, Sondra Bahr, Renee L. Brost, Yiqun Chen, Murat Cokol, Raamesh Deshpande, Zhijian Li, Zhen-Yuan Lin, Wendy Liang, Michaela Marback, Jadine Paw, Bryan-Joseph San Luis, Ermira Shuteriqi, Amy Hin Yan Tong, Nydia van Dyk, Iain M. Wallace, Joseph A. Whitney, Matthew T. Weirauch, Guoqing Zhong, Hongwei Zhu, Walid A. Houry, Michael Brudno, Sasan Ragibizadeh, Balázs Papp, Csaba Pál, Frederick P. Roth, Guri Giaever, Corey Nislow, Olga G. Troyanskaya, Howard Bussey, Gary D. Bader, Anne-Claude Gingras, Quaid D. Morris, Philip M. Kim, Chris A. Kaiser, Chad L. Myers, Brenda J. Andrews, Charles Boone
Science. Author manuscript; available in PMC 2017 Sep 15.
Published in final edited form as: Science. 2010 Jan 22; 327(5964): 425–431. doi: 10.1126/science.1180823
PMCID:
PMC5600254
AbstractArticlePDF–2.4M
19.
The Stress-Sensing TORC2 Complex Activates Yeast AGC-Family Protein Kinase Ypk1 at Multiple Novel Sites
Kristin L. Leskoske, Françoise M. Roelants, Maria Nieves Martinez Marshall, Jennifer M. Hill, Jeremy Thorner
Genetics. 2017 Sep; 207(1): 179–195. Published online 2017 Jul 26. doi: 10.1534/genetics.117.1124
PMCID:
PMC5586371
AbstractArticlePDF–1.7M
20.
A novel translational control mechanism involving RNA structures within coding sequences
Jennifer Jungfleisch, Danny D. Nedialkova, Ivan Dotu, Katherine E. Sloan, Neus Martinez-Bosch, Lukas Brüning, Emanuele Raineri, Pilar Navarro, Markus T. Bohnsack, Sebastian A. Leidel, Juana Díez
Genome Res. 2017 Jan; 27(1): 95–106. doi: 10.1101/gr.209015.116
Correction in:
Genome Res. 2017 Apr; 27(4): 663.
PMCID:
PMC5204348
AbstractArticlePDF–1.3M

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