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Items: 1 to 20 of 359

1.
Mitochondrial dysfunction and increased reactive oxygen species production in MECP2 mutant astrocytes and their impact on neurons
Danielle L. Tomasello, M. Inmaculada Barrasa, David Mankus, Katia I. Alarcon, Abigail K. R. Lytton-Jean, X. Shawn Liu, Rudolf Jaenisch
Sci Rep. 2024; 14: 20565. Published online 2024 Sep 4. doi: 10.1038/s41598-024-71040-y
PMCID:
PMC11374804
AbstractArticlePDF–4.9M
2.
A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex
Marisa Bedir, Emily Outwin, Rita Colnaghi, Lydia Bassett, Iga Abramowicz, Mark O’Driscoll
EMBO Rep. 2024 Aug; 25(8): 3432–3455. Published online 2024 Jun 28. doi: 10.1038/s44319-024-00184-9
PMCID:
PMC11315929
AbstractArticlePDF–3.4M
3.
Methyl-CpG-binding 2 K271 lactylation-mediated M2 macrophage polarization inhibits atherosclerosis
Liangqi Chen, Meiju Zhang, Xueyan Yang, Yanan Wang, Tuo Huang, Xin Li, Yunting Ban, Qifeng Li, Qingyuan Yang, Yongxiang Zhang, Yang Zheng, Di Wang, Xiaoqi Wang, Xiujie Shi, Maomao Zhang, Yong Sun, Jian Wu
Theranostics. 2024; 14(11): 4256–4277. Published online 2024 Jul 8. doi: 10.7150/thno.94738
PMCID:
PMC11303070
AbstractArticlePDF–12M
4.
DSBSO-Based XL-MS Analysis of Breast Cancer PDX Tissues to Delineate Protein Interaction Network in Clinical Samples
Fenglong Jiao, Clinton Yu, Andrew Wheat, Lijun Chen, Tung-Shing Mamie Lih, Hui Zhang, Lan Huang
J Proteome Res. Author manuscript; available in PMC 2024 Aug 3.
Published in final edited form as: J Proteome Res. 2024 Aug 2; 23(8): 3269–3279. Published online 2024 Feb 9. doi: 10.1021/acs.jproteome.3c00832
PMCID:
PMC11296914
AbstractArticlePDF–1.7M
5.
Chromatin composition alterations and the critical role of MeCP2 for epigenetic silencing of progesterone receptor-B gene in endometrial cancers
Yongli Chu, Yanlin Wang, Guanghua Zhang, Haibin Chen, Sean C. Dowdy, Yuning Xiong, Fengming Liu, Run Zhang, Jinping Li, Shi-Wen Jiang
Cell Mol Life Sci. 2014 Sep; 71(17): 3393–3408. Published online 2014 Feb 15. doi: 10.1007/s00018-014-1580-9
PMCID:
PMC11113436
AbstractArticlePDF–1.8M
6.
CRL4DCAF13 E3 ubiquitin ligase targets MeCP2 for degradation to prevent DNA hypermethylation and ensure normal transcription in growing oocytes
Peipei Ren, Xiaomei Tong, Junjian Li, Huifang Jiang, Siya Liu, Xiang Li, Mengru Lai, Weijie Yang, Yan Rong, Yingyi Zhang, Jiamin Jin, Yerong Ma, Weiwei Pan, Heng-Yu Fan, Songying Zhang, Yin-Li Zhang
Cell Mol Life Sci. 2024 Dec; 81(1): 165. Published online 2024 Apr 5. doi: 10.1007/s00018-024-05185-4
PMCID:
PMC10997554
AbstractArticlePDF–8.5M
7.
Genetic analysis of a pedigree with MECP2 duplication syndrome in China
Lan Zeng, Hui Zhu, Jin Wang, Qiyan Wang, Ying Pang, Zemin Luo, Ai Chen, Shengfang Qin, Shuyao Zhu
BMC Med Genomics. 2024; 17: 54. Published online 2024 Feb 19. doi: 10.1186/s12920-024-01831-9
PMCID:
PMC10875745
AbstractArticlePDF–2.4M
8.
Mutations in the transcriptional regulator MeCP2 severely impact key cellular and molecular signatures of human astrocytes during maturation
Jialin Sun, Sivan Osenberg, Austin Irwin, Li-Hua Ma, Nigel Lee, Yangfei Xiang, Feng Li, Ying-Wooi Wan, In-Hyun Park, Mirjana Maletic-Savatic, Nurit Ballas
Cell Rep. Author manuscript; available in PMC 2024 Feb 9.
Published in final edited form as: Cell Rep. 2023 Jan 31; 42(1): 111942. Published online 2023 Jan 5. doi: 10.1016/j.celrep.2022.111942
PMCID:
PMC10857774
AbstractArticlePDF–4.3M
9.
Analysis of the interplay between MeCP2 and histone H1 during in vitro differentiation of human ReNCell neural progenitor cells
Edilene Siqueira, Bo-Hyun Kim, Larry Reser, Robert Chow, Kerry Delaney, Manel Esteller, Mark M. Ross, Jeffrey Shabanowitz, Donald F. Hunt, Sonia Guil, Juan Ausió
Epigenetics. 2023; 18(1): 2276425. Published online 2023 Nov 17. doi: 10.1080/15592294.2023.2276425
PMCID:
PMC10769555
AbstractArticlePDF–7.1M
10.
TRIM28-mediated nucleocapsid protein SUMOylation enhances SARS-CoV-2 virulence
Jiang Ren, Shuai Wang, Zhi Zong, Ting Pan, Sijia Liu, Wei Mao, Huizhe Huang, Xiaohua Yan, Bing Yang, Xin He, Fangfang Zhou, Long Zhang
Nat Commun. 2024; 15: 244. Published online 2024 Jan 4. doi: 10.1038/s41467-023-44502-6
PMCID:
PMC10764958
AbstractArticlePDF–4.4M
11.
Systemic proteome phenotypes reveal defective metabolic flexibility in Mecp2 mutants
Stephanie A Zlatic, Erica Werner, Veda Surapaneni, Chelsea E Lee, Avanti Gokhale, Kaela Singleton, Duc Duong, Amanda Crocker, Karen Gentile, Frank Middleton, Joseph Martin Dalloul, William Li-Yun Liu, Anupam Patgiri, Daniel Tarquinio, Randall Carpenter, Victor Faundez
Hum Mol Genet. 2024 Jan 1; 33(1): 12–32. Published online 2023 Sep 15. doi: 10.1093/hmg/ddad154
PMCID:
PMC10729867
AbstractArticlePDF–3.3M
12.
Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates
Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert
Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644
PMCID:
PMC10565876
AbstractArticlePDF–3.7M
13.
Exploring Gastrointestinal Health in MECP2 Duplication Syndrome
Davut Pehlivan, Muharrem Ak, Daniel G. Glaze, Bernhard Suter, Kathleen J. Motil
Neurogastroenterol Motil. Author manuscript; available in PMC 2024 Aug 1.
Published in final edited form as: Neurogastroenterol Motil. 2023 Aug; 35(8): e14601. Published online 2023 Apr 30. doi: 10.1111/nmo.14601
PMCID:
PMC10524027
AbstractArticlePDF–897K
14.
Methyl-CpG binding protein 2 expression is associated with symptom severity in patients with PTSD in a sex-dependent manner
Livia Cosentino, Stephanie H. Witt, Helene Dukal, Francesca Zidda, Sebastian Siehl, Herta Flor, Bianca De Filippis
Transl Psychiatry. 2023; 13: 249. Published online 2023 Jul 7. doi: 10.1038/s41398-023-02529-9
PMCID:
PMC10329035
AbstractArticlePDF–840K
15.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
16.
Interleukin 1β triggers synaptic and memory deficits in Herpes simplex virus type-1-infected mice by downregulating the expression of synaptic plasticity-related genes via the epigenetic MeCP2/HDAC4 complex
Domenica Donatella Li Puma, Claudia Colussi, Bruno Bandiera, Giulia Puliatti, Marco Rinaudo, Sara Cocco, Fabiola Paciello, Agnese Re, Cristian Ripoli, Giovanna De Chiara, Alessia Bertozzi, Anna Teresa Palamara, Roberto Piacentini, Claudio Grassi
Cell Mol Life Sci. 2023 Jun; 80(6): 172. Published online 2023 Jun 1. doi: 10.1007/s00018-023-04817-5
PMCID:
PMC10234878
AbstractArticlePDF–4.4M
17.
MECP2 germline mosaicism plays an important part in the inheritance of Rett syndrome: a study of MECP2 germline mosaicism in males
Yongxin Wen, Jiaping Wang, Qingping Zhang, Xiaoxu Yang, Liping Wei, Xinhua Bao
BMC Med. 2023; 21: 155. Published online 2023 Apr 20. doi: 10.1186/s12916-023-02846-2
PMCID:
PMC10120091
AbstractArticlePDF–2.1M
18.
DDX47, MeCP2, and other functionally heterogeneous factors protect cells from harmful R loops
Esther Marchena-Cruz, Lola P. Camino, Jay Bhandari, Sónia Silva, José Javier Marqueta-Gracia, Shahad A. Amdeen, Cristina Guillén-Mendoza, María L. García-Rubio, José M. Calderón-Montaño, Xiaoyu Xue, Rosa Luna, Andrés Aguilera
Cell Rep. 2023 Mar 28; 42(3): 112148. Published online 2023 Feb 23. doi: 10.1016/j.celrep.2023.112148
PMCID:
PMC10066596
AbstractArticle
19.
A screen for MeCP2-TBL1 interaction inhibitors using a luminescence-based assay
Beatrice Alexander-Howden, Li Zhang, Almer M. van der Sloot, Sylvain Tollis, Daniel J. St-Cyr, Frank Sicheri, Adrian P. Bird, Mike Tyers, Matthew J. Lyst
Sci Rep. 2023; 13: 3868. Published online 2023 Mar 8. doi: 10.1038/s41598-023-29915-z
PMCID:
PMC9995496
AbstractArticlePDF–2.4M
20.
MiR-422a promotes adipogenesis via MeCP2 downregulation in human bone marrow mesenchymal stem cells
Angelica Giuliani, Jacopo Sabbatinelli, Stefano Amatori, Laura Graciotti, Andrea Silvestrini, Giulia Matacchione, Deborah Ramini, Emanuela Mensà, Francesco Prattichizzo, Lucia Babini, Domenico Mattiucci, Elena Marinelli Busilacchi, Maria Giulia Bacalini, Emma Espinosa, Fabrizia Lattanzio, Antonio Domenico Procopio, Fabiola Olivieri, Antonella Poloni, Mirco Fanelli, Maria Rita Rippo
Cell Mol Life Sci. 2023 Mar; 80(3): 75. Published online 2023 Feb 27. doi: 10.1007/s00018-023-04719-6
PMCID:
PMC9971129
AbstractArticlePDF–2.3M

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