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Select item 108408041.

A Caenorhabditis elegans model of adenylosuccinate lyase deficiency reveals neuromuscular and reproductive phenotypes of distinct etiology

Adam R. Fenton, Haley N. Janowitz, Latisha P. Franklin, Riley G. Young, Corinna A. Moro, Michael V. DeGennaro, Melanie R. McReynolds, Wenqing Wang, Wendy Hanna-Rose

Mol Genet Metab. Author manuscript; available in PMC 2024 Nov 1.

Published in final edited form as: Mol Genet Metab. 2023 Nov; 140(3): 107686. Published online 2023 Aug 15. doi: 10.1016/j.ymgme.2023.107686

PMCID:: PMC10840804

Abstract Article PDF–1.0M

Select item 108351292.

Amino acid and protein specificity of protein fatty acylation in C. elegans

Bingsen Zhang, Yan Yu, Bennett W. Fox, Yinong Liu, Venkatesh P. Thirumalaikumar, Aleksandra Skirycz, Hening Lin, Frank C. Schroeder

Proc Natl Acad Sci U S A. 2024 Jan 30; 121(5): e2307515121. Published online 2024 Jan 22. doi: 10.1073/pnas.2307515121

PMCID:: PMC10835129

Abstract Article PDF–1.4M

Select item 105281053.

A novel endoplasmic reticulum adaptation is critical for the longlived Caenorhabditis elegans rpn-10 proteasomal mutant

Meghna N. Chinchankar, William B. Taylor, Su-Hyuk Ko, Ellen C. Apple, Karl A. Rodriguez, Lizhen Chen, Alfred L. Fisher

Biochim Biophys Acta Gene Regul Mech. Author manuscript; available in PMC 2024 Sep 1.

Published in final edited form as: Biochim Biophys Acta Gene Regul Mech. 2023 Sep; 1866(3): 194957. Published online 2023 Jun 22. doi: 10.1016/j.bbagrm.2023.194957

PMCID:: PMC10528105

Abstract Article PDF–2.4M

Select item 105208894.

AKIR-1 regulates proteasome subcellular function in Caenorhabditis elegans

Johanna Pispa, Elisa Mikkonen, Leena Arpalahti, Congyu Jin, Carmen Martínez-Fernández, Julián Cerón, Carina I. Holmberg

iScience. 2023 Oct 20; 26(10): 107886. Published online 2023 Sep 11. doi: 10.1016/j.isci.2023.107886

PMCID:: PMC10520889

Abstract Article PDF–3.9M

Select item 103205245.

A proton-inhibited DEG/ENaC ion channel maintains neuronal ionstasis and promotes neuronal survival under stress

Dionysia Petratou, Martha Gjikolaj, Eva Kaulich, William Schafer, Nektarios Tavernarakis

iScience. 2023 Jul 21; 26(7): 107117. Published online 2023 Jun 14. doi: 10.1016/j.isci.2023.107117

PMCID:: PMC10320524

Abstract Article PDF–8.3M

Select item 101053286.

Yolk-deprived Caenorhabditis elegans secure brood size at the expense of competitive fitness

Ellen Geens, Pieter Van de Walle, Francesca Caroti, Rob Jelier, Christian Steuwe, Liliane Schoofs, Liesbet Temmerman

Life Sci Alliance. 2023 Jun; 6(6): e202201675. Published online 2023 Apr 14. doi: 10.26508/lsa.202201675

PMCID:: PMC10105328

Abstract Article PDF–2.0M

Select item 97291077.

ER-associated RNA silencing promotes ER quality control

Sotirios Efstathiou, Franziska Ottens, Lena-Sophie Schütter, Sonia Ravanelli, Nikolaos Charmpilas, Aljona Gutschmidt, Jérémie Le Pen, Niels H. Gehring, Eric A. Miska, Jorge Bouças, Thorsten Hoppe

Nat Cell Biol. 2022; 24(12): 1714–1725. Published online 2022 Dec 5. doi: 10.1038/s41556-022-01025-4

PMCID:: PMC9729107

Abstract Article PDF–7.1M

Select item 96488488.

Exon-dependent transcriptional adaptation by exon-junction complex proteins Y14/RNP-4 and MAGOH/MAG-1 in Caenorhabditis elegans

Jesus Fernandez-Abascal, Lei Wang, Bianca Graziano, Christina K. Johnson, Laura Bianchi

PLoS Genet. 2022 Oct; 18(10): e1010488. Published online 2022 Oct 31. doi: 10.1371/journal.pgen.1010488

PMCID:: PMC9648848

Abstract Article PDF–2.5M

Select item 88493379.

Release of CHK-2 from PPM-1.D anchorage schedules meiotic entry

Antoine Baudrimont, Dimitra Paouneskou, Ariz Mohammad, Raffael Lichtenberger, Joshua Blundon, Yumi Kim, Markus Hartl, Sebastian Falk, Tim Schedl, Verena Jantsch

Sci Adv. 2022 Feb; 8(7): eabl8861. Published online 2022 Feb 16. doi: 10.1126/sciadv.abl8861

PMCID:: PMC8849337

Abstract Article PDF–7.2M

Select item 879207410.

Multi-omics analysis identifies essential regulators of mitochondrial stress response in two wild-type C. elegans strains

Arwen W. Gao, Gaby El Alam, Amélia Lalou, Terytty Yang Li, Marte Molenaars, Yunyun Zhu, Katherine A. Overmyer, Evgenia Shishkova, Kevin Hof, Maroun Bou Sleiman, Riekelt H. Houtkooper, Joshua J. Coon, Johan Auwerx

iScience. 2022 Feb 18; 25(2): 103734. Published online 2022 Jan 5. doi: 10.1016/j.isci.2022.103734

PMCID:: PMC8792074

Abstract Article PDF–4.6M

Select item 875312211.

Gene regulatory network inference in long-lived C. elegans reveals modular properties that are predictive of novel aging genes

Manusnan Suriyalaksh, Celia Raimondi, Abraham Mains, Anne Segonds-Pichon, Shahzabe Mukhtar, Sharlene Murdoch, Rebeca Aldunate, Felix Krueger, Roger Guimerà, Simon Andrews, Marta Sales-Pardo, Olivia Casanueva

iScience. 2022 Jan 21; 25(1): 103663. Published online 2021 Dec 20. doi: 10.1016/j.isci.2021.103663

PMCID:: PMC8753122

Abstract Article PDF–4.6M

Select item 857078812.

An autoregulation loop in fust-1 for circular RNA regulation in Caenorhabditis elegans

Dong Cao

Genetics. 2021 Nov; 219(3): iyab145. Published online 2021 Sep 7. doi: 10.1093/genetics/iyab145

PMCID:: PMC8570788

Abstract Article PDF–1.1M

Select item 844104813.

Base excision repair causes age-dependent accumulation of single-stranded DNA breaks that contribute to Parkinson disease pathology

Tanima SenGupta, Konstantinos Palikaras, Ying Q. Esbensen, Georgios Konstantinidis, Francisco Jose Naranjo Galindo, Kavya Achanta, Henok Kassahun, Ioanna Stavgiannoudaki, Vilhelm A. Bohr, Mansour Akbari, Johannes Gaare, Charalampos Tzoulis, Nektarios Tavernarakis, Hilde Nilsen

Cell Rep. 2021 Sep 7; 36(10): 109668. Published online 2021 Sep 7. doi: 10.1016/j.celrep.2021.109668

PMCID:: PMC8441048

Abstract Article

Select item 794118114.

Reduced insulin/IGF1 signaling prevents immune aging via ZIP-10/bZIP–mediated feedforward loop

Yujin Lee, Yoonji Jung, Dae-Eun Jeong, Wooseon Hwang, Seokjin Ham, Hae-Eun H. Park, Sujeong Kwon, Jasmine M. Ashraf, Coleen T. Murphy, Seung-Jae V. Lee

J Cell Biol. 2021 May 3; 220(5): e202006174. Published online 2021 Mar 5. doi: 10.1083/jcb.202006174