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Select item 116169981.

Saccharomyces cerevisiae Rev7 promotes non-homologous end-joining by blocking Mre11 nuclease and Rad50’s ATPase activities and homologous recombination

Sugith Badugu, Kshitiza Mohan Dhyani, Manoj Thakur, Kalappa Muniyappa

eLife. 2024; 13: RP96933. Published online 2024 Dec 4. doi: 10.7554/eLife.96933

PMCID:: PMC11616998

Abstract Article PDF–5.2M

Select item 113417642.

Sae2 controls Mre11 endo- and exonuclease activities by different mechanisms

Tomoki Tamai, Giordano Reginato, Ryusei Ojiri, Issei Morita, Alexandra Avrutis, Petr Cejka, Miki Shinohara, Katsunori Sugimoto

Nat Commun. 2024; 15: 7221. Published online 2024 Aug 22. doi: 10.1038/s41467-024-51493-5

PMCID:: PMC11341764

Abstract Article PDF–3.6M

Select item 112845633.

Exo1 cooperates with Tel1/ATM in promoting recombination events at DNA replication forks

Michela Galli, Chiara Frigerio, Chiara Vittoria Colombo, Erika Casari, Maria Pia Longhese, Michela Clerici

iScience. 2024 Aug 16; 27(8): 110410. Published online 2024 Jun 28. doi: 10.1016/j.isci.2024.110410

PMCID:: PMC11284563

Abstract Article PDF–5.4M

Select item 112832334.

A comparative analysis of NADPH supply strategies in Saccharomyces cerevisiae: Production of d-xylitol from d-xylose as a case study

Priti Regmi, Melanie Knesebeck, Eckhard Boles, Dirk Weuster-Botz, Mislav Oreb

Metab Eng Commun. 2024 Dec; 19: e00245. Published online 2024 Jul 5. doi: 10.1016/j.mec.2024.e00245

PMCID:: PMC11283233

Abstract Article PDF–4.9M

Select item 110770765.

Physical interaction with Spo11 mediates the localisation of Mre11 to chromatin in meiosis and promotes its nuclease activity

Rakesh Aithal, Kuldeep Nangalia, Mario Spirek, Doris Chen, Franz Klein, Lumir Krejci

Nucleic Acids Res. 2024 May 8; 52(8): 4328–4343. Published online 2024 Feb 26. doi: 10.1093/nar/gkae111

PMCID:: PMC11077076

Abstract Article PDF–1.8M

Select item 107001386.

The social and structural architecture of the yeast protein interactome

André C. Michaelis, Andreas-David Brunner, Maximilian Zwiebel, Florian Meier, Maximilian T. Strauss, Isabell Bludau, Matthias Mann

Nature. 2023; 624(7990): 192–200. Published online 2023 Nov 15. doi: 10.1038/s41586-023-06739-5

PMCID:: PMC10700138

Abstract Article PDF–20M

Select item 105517007.

Misregulation of cell cycle-dependent methylation of budding yeast CENP-A contributes to chromosomal instability

Prashant K. Mishra, Wei-Chun Au, Pedro G. Castineira, Nazrin Ali, John Stanton, Lars Boeckmann, Yoshimitsu Takahashi, Michael Costanzo, Charles Boone, Kerry S. Bloom, Peter H. Thorpe, Munira A. Basrai

Mol Biol Cell. 2023 Sep 1; 34(10): ar99. Published online 2023 Aug 17. doi: 10.1091/mbc.E23-03-0108

PMCID:: PMC10551700

Abstract Article PDF–3.7M

Select item 105503218.

Mitochondrial superoxide dismutase Sod2 suppresses nuclear genome instability during oxidative stress

Sonia Vidushi Gupta, Lillian Campos, Kristina Hildegard Schmidt

Genetics. 2023 Oct; 225(2): iyad147. Published online 2023 Aug 29. doi: 10.1093/genetics/iyad147

PMCID:: PMC10550321

Abstract Article PDF–1.2M

Select item 103083739.

Ubx5‐Cdc48 assists the protease Wss1 at DNA‐protein crosslink sites in yeast

Audrey Noireterre, Nataliia Serbyn, Ivona Bagdiul, Françoise Stutz

EMBO J. 2023 Jul; 42(13): e113609. Published online 2023 May 5. doi: 10.15252/embj.2023113609

PMCID:: PMC10308373

Abstract Article PDF–8.0M

Select item 1023336810.

A systematic proximity ligation approach to studying protein‐substrate specificity identifies the substrate spectrum of the Ssh1 translocon

Nir Cohen, Naama Aviram, Maya Schuldiner

EMBO J. 2023 Jun; 42(11): e113385. Published online 2023 Apr 19. doi: 10.15252/embj.2022113385

PMCID:: PMC10233368

Abstract Article PDF–1.2M

Select item 998453211.

Genetic requirements for repair of lesions caused by single genomic ribonucleotides in S phase

Natalie Schindler, Matthias Tonn, Vanessa Kellner, Jia Jun Fung, Arianna Lockhart, Olga Vydzhak, Thomas Juretschke, Stefanie Möckel, Petra Beli, Anton Khmelinskii, Brian Luke

Nat Commun. 2023; 14: 1227. Published online 2023 Mar 3. doi: 10.1038/s41467-023-36866-6

PMCID:: PMC9984532

Abstract Article PDF–3.0M

Select item 997687712.

The Ku complex promotes DNA end-bridging and this function is antagonized by Tel1/ATM kinase

Carlo Rinaldi, Paolo Pizzul, Erika Casari, Marco Mangiagalli, Renata Tisi, Maria Pia Longhese

Nucleic Acids Res. 2023 Feb 28; 51(4): 1783–1802. Published online 2023 Feb 10. doi: 10.1093/nar/gkad062

PMCID:: PMC9976877

Abstract Article PDF–6.3M

Select item 983634813.

A synthetic genetic array screen for interactions with the RNA helicase DED1 during cell stress in budding yeast

Sara B Carey, Hannah M List, Ashwin Siby, Paolo Guerra, Timothy A Bolger

G3 (Bethesda) 2023 Jan; 13(1): jkac296. Published online 2022 Nov 21. doi: 10.1093/g3journal/jkac296

PMCID:: PMC9836348

Abstract Article PDF–857K

Select item 963098614.

A balancing act: interactions within NuA4/TIP60 regulate picNuA4 function in Saccharomyces cerevisiae and humans

Phoebe Y T Lu, Alyssa C Kirlin, Maria J Aristizabal, Hilary T Brewis, Nancy Lévesque, Dheva T Setiaputra, Nikita Avvakumov, Joris J Benschop, Marian Groot Koerkamp, Frank C P Holstege, Nevan J Krogan, Calvin K Yip, Jacques Côté, Michael S Kobor

Genetics. 2022 Nov; 222(3): iyac136. Published online 2022 Sep 6. doi: 10.1093/genetics/iyac136

PMCID:: PMC9630986

Abstract Article PDF–2.2M

Select item 929978815.

The Bur1 cyclin‐dependent kinase regulates telomere length in Saccharomyces cerevisiae

Carla J. Connelly, Sofia Vidal‐Cardenas, Stephanie Goldsmith, Carol W. Greider

Yeast. 2022 Mar; 39(3): 177–192. Published online 2021 Dec 2. doi: 10.1002/yea.3680

PMCID:: PMC9299788

Abstract Article PDF–651K

Select item 920981116.

New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources

Stacia R Engel, Edith D Wong, Robert S Nash, Suzi Aleksander, Micheal Alexander, Eric Douglass, Kalpana Karra, Stuart R Miyasato, Matt Simison, Marek S Skrzypek, Shuai Weng, J Michael Cherry

Genetics. 2022 Apr; 220(4): iyab224. Published online 2021 Dec 13. doi: 10.1093/genetics/iyab224

PMCID:: PMC9209811

Abstract Article PDF–818K

Select item 911754617.

Nej1 interacts with Sae2 at DNA double-stranded breaks to inhibit DNA resection

Aditya Mojumdar, Nancy Adam, Jennifer A. Cobb

J Biol Chem. 2022 Jun; 298(6): 101937. Published online 2022 Apr 13. doi: 10.1016/j.jbc.2022.101937

PMCID:: PMC9117546

Abstract Article PDF–2.7M

Select item 906175318.

Mre11-Rad50 oligomerization promotes DNA double-strand break repair

Vera M. Kissling, Giordano Reginato, Eliana Bianco, Kristina Kasaciunaite, Janny Tilma, Gea Cereghetti, Natalie Schindler, Sung Sik Lee, Raphaël Guérois, Brian Luke, Ralf Seidel, Petr Cejka, Matthias Peter

Nat Commun. 2022; 13: 2374. Published online 2022 May 2. doi: 10.1038/s41467-022-29841-0

PMCID:: PMC9061753

Abstract Article PDF–4.3M

Select item 868275619.

Mapping yeast mitotic 5′ resection at base resolution reveals the sequence and positional dependence of nucleases in vivo

Dominic Bazzano, Stephanie Lomonaco, Thomas E Wilson

Nucleic Acids Res. 2021 Dec 16; 49(22): 12607–12621. Published online 2021 Jul 15. doi: 10.1093/nar/gkab597

PMCID:: PMC8682756

Abstract Article PDF–4.9M

Select item 856163520.

A regulatory phosphorylation site on Mec1 controls chromatin occupancy of RNA polymerases during replication stress

Verena Hurst, Kiran Challa, Felix Jonas, Romain Forey, Ragna Sack, Jan Seebacher, Christoph D Schmid, Naama Barkai, Kenji Shimada, Susan M Gasser, Jérôme Poli

EMBO J. 2021 Nov 2; 40(21): e108439. Published online 2021 Sep 27. doi: 10.15252/embj.2021108439