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Select item 115684661.

A human DCC variant causing mirror movement disorder reveals that the WAVE regulatory complex mediates axon guidance by netrin-1-DCC

Karina Chaudhari, Kaiyue Zhang, Patricia T. Yam, Yixin Zang, Daniel A. Kramer, Sarah Gagnon, Sabrina Schlienger, Sara Calabretta, Jean-Francois Michaud, Meagan Collins, Junmei Wang, Myriam Srour, Baoyu Chen, Frédéric Charron, Greg J. Bashaw

Sci Signal. Author manuscript; available in PMC 2024 Nov 16.

Published in final edited form as: Sci Signal. 2024 Oct; 17(856): eadk2345. Published online 2024 Oct 1. doi: 10.1126/scisignal.adk2345

PMCID:: PMC11568466

Article PDF–3.3M

Select item 109457072.

Comparative interactome analysis of α-arrestin families in human and Drosophila

Kyung-Tae Lee, Inez KA Pranoto, Soon-Young Kim, Hee-Joo Choi, Ngoc Bao To, Hansong Chae, Jeong-Yeon Lee, Jung-Eun Kim, Young V Kwon, Jin-Wu Nam

eLife. 2024; 12: RP88328. Published online 2024 Jan 25. doi: 10.7554/eLife.88328

PMCID:: PMC10945707

Article PDF–2.8M

Select item 105086923.

Fat2 polarizes Lar and Sema5c to coordinate the motility of collectively migrating epithelial cells

Audrey Miller Williams, Sally Horne-Badovinac

J Cell Sci. 2024 Mar 1; 137(5): jcs261173. Published online 2023 Sep 11. doi: 10.1242/jcs.261173

PMCID:: PMC10508692

Article

Select item 99411354.

SREBP modulates the NADP⁺/NADPH cycle to control night sleep in Drosophila

Vittoria Mariano, Alexandros K. Kanellopoulos, Giuseppe Aiello, Adrian C. Lo, Eric Legius, Tilmann Achsel, Claudia Bagni

Nat Commun. 2023; 14: 763. Published online 2023 Feb 20. doi: 10.1038/s41467-022-35577-8

PMCID:: PMC9941135

Article PDF–2.9M

Select item 97629445.

Activating RAC1 variants in the switch II region cause a developmental syndrome and alter neuronal morphology

Siddharth Banka, Abigail Bennington, Martin J Baker, Ellen Rijckmans, Giuliana D Clemente, Nurhuda Mohamad Ansor, Hilary Sito, Pritha Prasad, Kwame Anyane-Yeboa, Lauren Badalato, Boyan Dimitrov, David Fitzpatrick, Anna C E Hurst, Anna C Jansen, Melissa A Kelly, Ian Krantz, Claudine Rieubland, Meredith Ross, Natasha L Rudy, Javier Sanz, Katrien Stouffs, Zhuo Luan Xu, Angeliki Malliri, Marcelo G Kazanietz, Tom H Millard

Brain. 2022 Dec; 145(12): 4232–4245. Published online 2022 Feb 10. doi: 10.1093/brain/awac049

PMCID:: PMC9762944

Article PDF–1.3M

Select item 95762706.

Fat2 polarizes the WAVE complex in trans to align cell protrusions for collective migration

Audrey Miller Williams, Seth Donoughe, Edwin Munro, Sally Horne-Badovinac

eLife. 2022; 11: e78343. Published online 2022 Sep 26. doi: 10.7554/eLife.78343

PMCID:: PMC9576270

Article PDF–7.1M

Select item 94367527.

Leishmania amazonensis sabotages host cell SUMOylation for intracellular survival

Kendi Okuda, Miriam Maria Silva Costa Franco, Ari Yasunaga, Ricardo Gazzinelli, Michel Rabinovitch, Sara Cherry, Neal Silverman

iScience. 2022 Sep 16; 25(9): 104909. Published online 2022 Aug 13. doi: 10.1016/j.isci.2022.104909

PMCID:: PMC9436752

Article PDF–3.3M

Select item 87140738.

CK1α protects WAVE from degradation to regulate cell shape and motility in the immune response

Alexander Hirschhäuser, Marianne van Cann, Sven Bogdan

J Cell Sci. 2021 Dec 1; 134(23): jcs258891. Published online 2021 Dec 9. doi: 10.1242/jcs.258891

PMCID:: PMC8714073

Article

Select item 86644869.

Genome-wide phenotypic RNAi screen in the Drosophila wing: phenotypic description of functional classes

Ana López-Varea, Patricia Vega-Cuesta, Ana Ruiz-Gómez, Cristina M Ostalé, Cristina Molnar, Covadonga F Hevia, Mercedes Martín, Maria F Organista, Jesus de Celis, Joaquín Culí, Nuria Esteban, Jose F de Celis

G3 (Bethesda) 2021 Dec; 11(12): jkab349. Published online 2021 Oct 2. doi: 10.1093/g3journal/jkab349

PMCID:: PMC8664486

Article PDF–3.1M

Select item 861042010.

DAAM mediates the assembly of long-lived, treadmilling stress fibers in collectively migrating epithelial cells in Drosophila

Kristin M Sherrard, Maureen Cetera, Sally Horne-Badovinac

eLife. 2021; 10: e72881. Published online 2021 Nov 23. doi: 10.7554/eLife.72881

PMCID:: PMC8610420

Article PDF–19M

Select item 809643611.

Robo recruitment of the Wave regulatory complex plays an essential and conserved role in midline repulsion

Karina Chaudhari, Madhavi Gorla, Chao Chang, Artur Kania, Greg J Bashaw

eLife. 2021; 10: e64474. Published online 2021 Apr 12. doi: 10.7554/eLife.64474

PMCID:: PMC8096436

Article PDF–7.0M

Select item 786265812.

Filopodia-based contact stimulation of cell migration drives tissue morphogenesis

Maik C. Bischoff, Sebastian Lieb, Renate Renkawitz-Pohl, Sven Bogdan

Nat Commun. 2021; 12: 791. Published online 2021 Feb 4. doi: 10.1038/s41467-020-20362-2

PMCID:: PMC7862658

Article PDF–14M

Select item 750397313.

Investigating Developmental and Epileptic Encephalopathy Using Drosophila melanogaster

Akari Takai, Masamitsu Yamaguchi, Hideki Yoshida, Tomohiro Chiyonobu

Int J Mol Sci. 2020 Sep; 21(17): 6442. Published online 2020 Sep 3. doi: 10.3390/ijms21176442

PMCID:: PMC7503973

Article PDF–1.6M

Select item 731374014.

Drosophila models of pathogenic copy-number variant genes show global and non-neuronal defects during development

Tanzeen Yusuff, Matthew Jensen, Sneha Yennawar, Lucilla Pizzo, Siddharth Karthikeyan, Dagny J. Gould, Avik Sarker, Erika Gedvilaite, Yurika Matsui, Janani Iyer, Zhi-Chun Lai, Santhosh Girirajan

PLoS Genet. 2020 Jun; 16(6): e1008792. Published online 2020 Jun 24. doi: 10.1371/journal.pgen.1008792

PMCID:: PMC7313740

Article PDF–5.4M

Select item 719622715.

The first quarter of the C-terminal domain of Abelson regulates the WAVE regulatory complex and Enabled in axon guidance

Han Sian Joshua Cheong, Mark Nona, Samantha Barbara Guerra, Mark Francis VanBerkum

Neural Dev. 2020; 15: 7. Published online 2020 May 2. doi: 10.1186/s13064-020-00144-8

PMCID:: PMC7196227

Article PDF–5.7M

Select item 680034316.

Genetic dissection of active forgetting in labile and consolidated memories in Drosophila

Yang Gao, Yichun Shuai, Xuchen Zhang, Yuwei Peng, Lianzhang Wang, Jing He, Yi Zhong, Qian Li

Proc Natl Acad Sci U S A. 2019 Oct 15; 116(42): 21191–21197. Published online 2019 Sep 5. doi: 10.1073/pnas.1903763116

PMCID:: PMC6800343

Article PDF–819K

Select item 674750517.

Autism Spectrum Disorder-Related Syndromes: Modeling with Drosophila and Rodents

Ibuki Ueoka, Hang Thi Nguyet Pham, Kinzo Matsumoto, Masamitsu Yamaguchi

Int J Mol Sci. 2019 Sep; 20(17): 4071. Published online 2019 Aug 21. doi: 10.3390/ijms20174071

Correction in:: Int J Mol Sci. 2020 Nov; 21(21): 8093.

PMCID:: PMC6747505

Article PDF–2.1M

Select item 667974618.

Domain-specific cognitive impairments in humans and flies with reduced CYFIP1 dosage

Young Jae Woo, Alexandras K. Kanellopoulos, Parisa Hemati, Jill Kirschen, Rebecca A. Nebel, Tao Wang, Claudia Bagni, Brett S. Abrahams

Biol Psychiatry. Author manuscript; available in PMC 2020 Aug 15.

Published in final edited form as: Biol Psychiatry. 2019 Aug 15; 86(4): 306–314. Published online 2019 Apr 17. doi: 10.1016/j.biopsych.2019.04.008

PMCID:: PMC6679746

Article PDF–1015K

Select item 667070219.

Mutational Analysis Establishes a Critical Role for the N Terminus of Fragile X Mental Retardation Protein FMRP

Simon P. Reeve, Xinda Lin, Bahar H. Sahin, Fangfang Jiang, Aiyu Yao, Zhihua Liu, Hui Zhi, Kendal Broadie, Wei Li, Angela Giangrande, Bassem A. Hassan, Yong Q. Zhang

J Neurosci. 2008 Mar 19; 28(12): 3221–3226. doi: 10.1523/JNEUROSCI.5528-07.2008

PMCID:: PMC6670702

Article PDF–470K

Select item 591198220.

Modeling Fragile X Syndrome in Drosophila

Małgorzata Drozd, Barbara Bardoni, Maria Capovilla

Front Mol Neurosci. 2018; 11: 124. Published online 2018 Apr 16. doi: 10.3389/fnmol.2018.00124

PMCID:: PMC5911982

Article PDF–806K

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