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Select item 109578971.

An evolutionary mechanism to assimilate new nutrient sensors into the mTORC1 pathway

Grace Y. Liu, Patrick Jouandin, Raymond E. Bahng, Norbert Perrimon, David M. Sabatini

Nat Commun. 2024; 15: 2517. Published online 2024 Mar 21. doi: 10.1038/s41467-024-46680-3

PMCID:: PMC10957897

Abstract Article PDF–2.0M

Select item 108833742.

Molecular mechanism of S-adenosylmethionine sensing by SAMTOR in mTORC1 signaling

Xin Tang, Yifan Zhang, Guanchao Wang, Chunxiao Zhang, Fang Wang, Jiawen Shi, Tianlong Zhang, Jianping Ding

Sci Adv. 2022 Jul; 8(26): eabn3868. Published online 2022 Jul 1. doi: 10.1126/sciadv.abn3868

PMCID:: PMC10883374

Abstract Article PDF–3.5M

Select item 102533713.

Genetic Targeting of dSAMTOR, A Negative dTORC1 Regulator, during Drosophila Aging: A Tissue-Specific Pathology

Stamatia A. Katarachia, Sophia P. Markaki, Athanassios D. Velentzas, Dimitrios J. Stravopodis

Int J Mol Sci. 2023 Jun; 24(11): 9676. Published online 2023 Jun 2. doi: 10.3390/ijms24119676

PMCID:: PMC10253371

Abstract Article PDF–11M

Select item 80791504.

Methionine restriction breaks obligatory coupling of cell proliferation and death by an oncogene Src in Drosophila

Hiroshi Nishida, Morihiro Okada, Lynna Yang, Tomomi Takano, Sho Tabata, Tomoyoshi Soga, Diana M Ho, Jongkyeong Chung, Yasuhiro Minami, Sa Kan Yoo

eLife. 2021; 10: e59809. Published online 2021 Apr 27. doi: 10.7554/eLife.59809

PMCID:: PMC8079150

Abstract Article PDF–6.6M

Select item 57473645.

SAMTOR is an S-adenosylmethionine sensor for the mTORC1 pathway

Xin Gu, Jose M. Orozco, Robert A. Saxton, Kendall J. Condon, Grace Y. Liu, Patrycja A. Krawczyk, Sonia M. Scaria, J. Wade Harper, Steven P. Gygi, David M. Sabatini

Science. Author manuscript; available in PMC 2018 Nov 10.

Published in final edited form as: Science. 2017 Nov 10; 358(6364): 813–818. doi: 10.1126/science.aao3265

PMCID:: PMC5747364

Abstract Article PDF–646K

Select item 57078056.

Landscape and evolution of tissue-specific alternative polyadenylation across Drosophila species

Piero Sanfilippo, Jiayu Wen, Eric C. Lai

Genome Biol. 2017; 18: 229. Published online 2017 Nov 30. doi: 10.1186/s13059-017-1358-0

PMCID:: PMC5707805

Abstract Article PDF–3.2M

Select item 56890027.

Transcription elongation rate has a tissue-specific impact on alternative cleavage and polyadenylation in Drosophila melanogaster

Xiaochuan Liu, Jaime Freitas, Dinghai Zheng, Marta S. Oliveira, Mainul Hoque, Torcato Martins, Telmo Henriques, Bin Tian, Alexandra Moreira

RNA. 2017 Dec; 23(12): 1807–1816. doi: 10.1261/rna.062661.117

PMCID:: PMC5689002

Abstract Article PDF–4.0M

Select item 45680258.

Genes conserved in bilaterians but jointly lost with Myc during nematode evolution are enriched in cell proliferation and cell migration functions

Albert J. Erives

Dev Genes Evol. 2015; 225(5): 259–273. Published online 2015 Jul 15. doi: 10.1007/s00427-015-0508-1

PMCID:: PMC4568025

Abstract Article PDF–2.8M

Select item 45283309.

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders

Madeline A. Crosby, L. Sian Gramates, Gilberto dos Santos, Beverley B. Matthews, Susan E. St. Pierre, Pinglei Zhou, Andrew J. Schroeder, Kathleen Falls, David B. Emmert, Susan M. Russo, William M. Gelbart, the FlyBase Consortium

G3 (Bethesda) 2015 Aug; 5(8): 1737–1749. Published online 2015 Jun 24. doi: 10.1534/g3.115.018937

PMCID:: PMC4528330

Abstract Article PDF–2.2M

Select item 452832910.

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data

Beverley B. Matthews, Gilberto dos Santos, Madeline A. Crosby, David B. Emmert, Susan E. St. Pierre, L. Sian Gramates, Pinglei Zhou, Andrew J. Schroeder, Kathleen Falls, Victor Strelets, Susan M. Russo, William M. Gelbart, the FlyBase Consortium

G3 (Bethesda) 2015 Aug; 5(8): 1721–1736. Published online 2015 Jun 24. doi: 10.1534/g3.115.018929

PMCID:: PMC4528329

Abstract Article PDF–4.9M

Select item 435288711.

The Release 6 reference sequence of the Drosophila melanogaster genome

Roger A. Hoskins, Joseph W. Carlson, Kenneth H. Wan, Soo Park, Ivonne Mendez, Samuel E. Galle, Benjamin W. Booth, Barret D. Pfeiffer, Reed A. George, Robert Svirskas, Martin Krzywinski, Jacqueline Schein, Maria Carmela Accardo, Elisabetta Damia, Giovanni Messina, María Méndez-Lago, Beatriz de Pablos, Olga V. Demakova, Evgeniya N. Andreyeva, Lidiya V. Boldyreva, Marco Marra, A. Bernardo Carvalho, Patrizio Dimitri, Alfredo Villasante, Igor F. Zhimulev, Gerald M. Rubin, Gary H. Karpen, Susan E. Celniker

Genome Res. 2015 Mar; 25(3): 445–458. doi: 10.1101/gr.185579.114

PMCID:: PMC4352887

Abstract Article PDF–1022K

Select item 427152712.

Phylostratigraphic Bias Creates Spurious Patterns of Genome Evolution

Bryan A. Moyers, Jianzhi Zhang

Mol Biol Evol. 2015 Jan 1; 32(1): 258–267. Published online 2014 Oct 13. doi: 10.1093/molbev/msu286

Correction in:: Mol Biol Evol. 2016 Nov; 33(11): 3031.

PMCID:: PMC4271527

Abstract Article PDF–618K

Select item 411190313.

Staufen targets coracle mRNA to Drosophila neuromuscular junctions and regulates GluRIIA synaptic accumulation and bouton number

Alejandra Gardiol, Daniel St Johnston

Dev Biol. 2014 Aug 15; 392(2): 153–167. doi: 10.1016/j.ydbio.2014.06.007

Correction in:: Dev Biol. 2014 Sep 15; 393(2): 320.

PMCID:: PMC4111903

Abstract Article PDF–12M

Select item 376484114.

RNAi Screening of Drosophila (Sophophora) melanogaster S2 Cells for Ricin Sensitivity and Resistance

Vidya Pawar, Antara De, Laura Briggs, Mahmoud M. Omar, Sean T. Sweeney, J. Michael Lord, Lynne M. Roberts, Robert A. Spooner, Kevin G. Moffat

J Biomol Screen. 2011 Apr; 16(4): 436–442. doi: 10.1177/1087057110397890

PMCID:: PMC3764841

Abstract Article PDF–391K

Select item 353067715.

High-fidelity promoter profiling reveals widespread alternative promoter usage and transposon-driven developmental gene expression

Philippe Batut, Alexander Dobin, Charles Plessy, Piero Carninci, Thomas R. Gingeras

Genome Res. 2013 Jan; 23(1): 169–180. doi: 10.1101/gr.139618.112

PMCID:: PMC3530677

Abstract Article PDF–1.5M

Select item 346946716.

The Many Landscapes of Recombination in Drosophila melanogaster

Josep M. Comeron, Ramesh Ratnappan, Samuel Bailin

PLoS Genet. 2012 Oct; 8(10): e1002905. Published online 2012 Oct 11. doi: 10.1371/journal.pgen.1002905

PMCID:: PMC3469467

Abstract Article PDF–1.6M

Select item 331904817.

A Protein Complex Network of Drosophila melanogaster

K. G. Guruharsha, J. -F. Rual, B. Zhai, J. Mintseris, P. Vaidya, N. Vaidya, C. Beekman, C. Wong, D. Y. Rhee, O. Cenaj, E. McKillip, S. Shah, M. Stapleton, K. H. Wan, C. Yu, B. Parsa, J. W. Carlson, X. Chen, B. Kapadia, K. VijayRaghavan, S. P. Gygi, S. E. Celniker, R. A. Obar, S. Artavanis-Tsakonas

Cell. Author manuscript; available in PMC 2012 Oct 28.

Published in final edited form as: Cell. 2011 Oct 28; 147(3): 690–703. doi: 10.1016/j.cell.2011.08.047

PMCID:: PMC3319048

Abstract Article PDF–3.2M

Select item 304044118.

A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionary-conserved pain gene

G. Gregory Neely, Andreas Hess, Michael Costigan, Alex C. Keene, Spyros Goulas, Michiel Langeslag, Robert S Griffin, Inna Belfer, Feng Dai, Shad Smith, Luda Diatchenko, Vaijayanti Gupta, Cui-ping Xia, Sabina Amann, Silke Kreitz, Cornelia Heindl-Erdmann, Susanne Wolz, Cindy V. Ly, Suchir Arora, Rinku Sarangi, Debasis Dan, Maria Novatchkova, Mark Rosenzweig, Dustin Gibson, Darwin Truong, Daniel Schramek, Tamara Zoranovic, Shane J. F. Cronin, Belinda Angjeli, Kay Brune, Georg Dietzl, William Maixner, Arabella Meixner, Winston Thomas, J. Andrew Pospisilik, Mattias Alenius, Michaela Kress, Sai Subramaniam, Paul A. Garrity, Hugo J. Bellen, Clifford J. Woolf, Josef M. Penninger

Cell. Author manuscript; available in PMC 2011 Nov 12.

Published in final edited form as: Cell. 2010 Nov 12; 143(4): 628–638. doi: 10.1016/j.cell.2010.09.047

PMCID:: PMC3040441

Abstract Article PDF–2.0M

Select item 285522119.

A global in vivo Drosophila RNAi screen identifies NOT3 as a conserved regulator of heart function

G. Gregory Neely, Keiji Kuba, Anthony Cammarato, Kazuya Isobe, Sabine Amann, Liyong Zhang, Mitsushige Murata, Lisa Elmén, Vaijayanti Gupta, Suchir Arora, Rinku Sarangi, Debasis Dan, Susumu Fujisawa, Takako Usami, Cui-ping Xia, Alex C. Keene, Nakissa N. Alayari, Hiroyuki Yamakawa, Ulrich Elling, Christian Berger, Maria Novatchkova, Rubina Koglgruber, Keiichi Fukuda, Hiroshi Nishina, Mitsuaki Isobe, J. Andrew Pospisilik, Yumiko Imai, Arne Pfeufer, Andrew A Hicks, Peter P. Pramstaller, Sai Subramaniam, Akinori Kimura, Karen Ocorr, Rolf Bodmer, Josef M. Penninger

Cell. Author manuscript; available in PMC 2011 Apr 2.

Published in final edited form as: Cell. 2010 Apr 2; 141(1): 142–153. doi: 10.1016/j.cell.2010.02.023

PMCID:: PMC2855221

Abstract Article PDF–5.3M

Select item 282505320.

Sequence Finishing and Mapping of Drosophila melanogaster Heterochromatin

Roger A. Hoskins, Joseph W. Carlson, Cameron Kennedy, David Acevedo, Martha Evans-Holm, Erwin Frise, Kenneth H. Wan, Soo Park, Maria Mendez-Lago, Fabrizio Rossi, Alfredo Villasante, Patrizio Dimitri, Gary H. Karpen, Susan E. Celniker

Science. Author manuscript; available in PMC 2010 Feb 19.

Published in final edited form as: Science. 2007 Jun 15; 316(5831): 1625–1628. doi: 10.1126/science.1139816

PMCID:: PMC2825053

Abstract Article PDF–858K

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