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Items: 1 to 20 of 28

1.
Serine Hydroxymethyltransferase 2 Deficiency in the Hematopoietic System Disrupts Erythropoiesis and Induces Anemia in Murine Models
Jisheng Li, Bowen Zhang, Yunqiao Li, Chuanli Liu, Xuan Tang, Jiahui Zhao, Xuetao Pei, Yanhua Li
Int J Mol Sci. 2024 Oct; 25(20): 11072. Published online 2024 Oct 15. doi: 10.3390/ijms252011072
PMCID:
PMC11508403
AbstractArticlePDF–17M
2.
SHMT2 Mediates Small‐Molecule‐Induced Alleviation of Alzheimer Pathology Via the 5′UTR‐dependent ADAM10 Translation Initiation
Li Song, Qiu‐Ling Pan, Gui‐Feng Zhou, Sheng‐Wei Liu, Bing‐Lin Zhu, Pei‐Jia Lin, Xiao‐Tong Hu, Jing‐Si Zha, Yan Long, Biao Luo, Jian Chen, Ying Tang, Jing Tang, Xiao‐Jiao Xiang, Xiao‐Yong Xie, Xiao‐Juan Deng, Guo‐Jun Chen
Adv Sci (Weinh) 2024 Mar; 11(11): 2305260. Published online 2024 Jan 6. doi: 10.1002/advs.202305260
PMCID:
PMC10953581
AbstractArticlePDF–11M
3.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
4.
SHMT2 reduces fatty liver but is necessary for liver inflammation and fibrosis in mice
Guohua Chen, Guoli Zhou, Lidong Zhai, Xun Bao, Nivedita Tiwari, Jing Li, Emilio Mottillo, Jian Wang
Commun Biol. 2024; 7: 173. Published online 2024 Feb 12. doi: 10.1038/s42003-024-05861-y
PMCID:
PMC10861579
AbstractArticlePDF–4.8M
5.
ALS-linked loss of Cyclin-F function affects HSP90
Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends
Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359
PMCID:
PMC9481933
AbstractArticlePDF–3.5M
6.
Liver and brain differential expression of one-carbon metabolism genes during ontogenesis
Apolline Imbard, Leslie Schwendimann, Sophie Lebon, Pierre Gressens, Henk J. Blom, Jean-François Benoist
Sci Rep. 2021; 11: 21132. Published online 2021 Oct 26. doi: 10.1038/s41598-021-00311-9
PMCID:
PMC8548596
AbstractArticlePDF–1.3M
7.
Downregulating Serine Hydroxymethyltransferase 2 Deteriorates Hepatic Ischemia-Reperfusion Injury through ROS/JNK/P53 Signaling in Mice
Hao Wu, He Bai, Shigang Duan, Fangchao Yuan
Biomed Res Int. 2019; 2019: 2712185. Published online 2019 Nov 18. doi: 10.1155/2019/2712185
PMCID:
PMC6885790
AbstractArticlePDF–5.0M
8.
Disruption of the mouse Shmt2 gene confers embryonic anaemia via foetal liver-specific metabolomic disorders
Haruna Tani, Takayuki Mito, Vidya Velagapudi, Kaori Ishikawa, Moe Umehara, Kazuto Nakada, Anu Suomalainen, Jun-Ichi Hayashi
Sci Rep. 2019; 9: 16054. Published online 2019 Nov 5. doi: 10.1038/s41598-019-52372-6
PMCID:
PMC6831688
AbstractArticlePDF–4.5M
9.
Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors
Hyeonwoo Kim, Christiane D. Wrann, Mark Jedrychowski, Sara Vidoni, Yukiko Kitase, Kenichi Nagano, Chenhe Zhou, Joshua Chou, Virginia-Jeni A. Parkman, Scott J. Novick, Timothy S. Strutzenberg, Bruce D. Pascal, Phuong T. Le, Daniel J. Brooks, Alexander M. Roche, Kaitlyn K. Gerber, Laura Mattheis, Wenjing Chen, Hua Tu, Mary L. Bouxsein, Patrick R. Griffin, Roland Baron, Clifford J. Rosen, Lynda F. Bonewald, Bruce M. Spiegelman
Cell. Author manuscript; available in PMC 2019 Dec 13.
Published in final edited form as: Cell. 2018 Dec 13; 175(7): 1756–1768.e17. doi: 10.1016/j.cell.2018.10.025
Correction in:
Cell. 2019 Jul 11; 178(2): 507–508.
PMCID:
PMC6298040
AbstractArticlePDF–1.2M
10.
Essential roles of mitochondrial biogenesis regulator Nrf1 in retinal development and homeostasis
Takae Kiyama, Ching-Kang Chen, Steven W Wang, Ping Pan, Zhenlin Ju, Jing Wang, Shinako Takada, William H Klein, Chai-An Mao
Mol Neurodegener. 2018; 13: 56. Published online 2018 Oct 17. doi: 10.1186/s13024-018-0287-z
PMCID:
PMC6192121
AbstractArticlePDF–12M
11.
Serine Catabolism by SHMT2 is Required for Proper Mitochondrial Translation Initiation and Maintenance of Formylmethionyl tRNAs
Denise R. Minton, Minwoo Nam, Daniel J. McLaughlin, Jong Shin, Erol C. Bayraktar, Samantha W. Alvarez, Vladislav O. Sviderskiy, Thales Papagiannakopoulos, David M. Sabatini, Kıvanç Birsoy, Richard Possemato
Mol Cell. Author manuscript; available in PMC 2019 Feb 15.
Published in final edited form as: Mol Cell. 2018 Feb 15; 69(4): 610–621.e5. doi: 10.1016/j.molcel.2018.01.024
PMCID:
PMC5819360
AbstractArticlePDF–1.8M
12.
The interactome of intact mitochondria by cross-linking mass spectrometry provides evidence for coexisting respiratory supercomplexes
Fan Liu, Philip Lössl, Beverley M. Rabbitts, Robert S. Balaban, Albert J. R. Heck
Mol Cell Proteomics. 2018 Feb; 17(2): 216–232. Published online 2017 Dec 8. doi: 10.1074/mcp.RA117.000470
PMCID:
PMC5795388
AbstractArticlePDF–4.4M
13.
Mice deficient in the Shmt2 gene have mitochondrial respiration defects and are embryonic lethal
Haruna Tani, Sakiko Ohnishi, Hiroshi Shitara, Takayuki Mito, Midori Yamaguchi, Hiromichi Yonekawa, Osamu Hashizume, Kaori Ishikawa, Kazuto Nakada, Jun-Ichi Hayashi
Sci Rep. 2018; 8: 425. Published online 2018 Jan 11. doi: 10.1038/s41598-017-18828-3
PMCID:
PMC5765156
AbstractArticlePDF–1.5M
14.
Karyopherin alpha 1 regulates satellite cell proliferation and survival by modulating nuclear import
Hyo-Jung Choo, Alicia Cutler, Franziska Rother, Michael Bader, Grace K. Pavlath
Stem Cells. Author manuscript; available in PMC 2017 Jun 1.
Published in final edited form as: Stem Cells. 2016 Nov; 34(11): 2784–2797. Published online 2016 Aug 1. doi: 10.1002/stem.2467
PMCID:
PMC5247404
AbstractArticlePDF–2.2M
15.
Deletion of Mthfd1l causes embryonic lethality and neural tube and craniofacial defects in mice
Jessica Momb, Jordan P. Lewandowski, Joshua D. Bryant, Rebecca Fitch, Deborah R. Surman, Steven A. Vokes, Dean R. Appling
Proc Natl Acad Sci U S A. 2013 Jan 8; 110(2): 549–554. Published online 2012 Dec 24. doi: 10.1073/pnas.1211199110
PMCID:
PMC3545794
AbstractArticlePDF–872K
16.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
17.
A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo
Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio
PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582
PMCID:
PMC3022534
AbstractArticlePDF–3.8M
18.
A mitochondrial protein compendium elucidates complex I disease biology
David J. Pagliarini, Sarah E. Calvo, Betty Chang, Sunil A. Sheth, Scott B. Vafai, Shao-En Ong, Geoffrey A. Walford, Canny Sugiana, Avihu Boneh, William K. Chen, David E. Hill, Marc Vidal, James G. Evans, David R. Thorburn, Steven A. Carr, Vamsi K. Mootha
Cell. Author manuscript; available in PMC 2009 Nov 18.
Published in final edited form as: Cell. 2008 Jul 11; 134(1): 112–123. doi: 10.1016/j.cell.2008.06.016
PMCID:
PMC2778844
AbstractArticlePDF–1.2M
19.
SHMT1 and SHMT2 Are Functionally Redundant in Nuclear De novo Thymidylate Biosynthesis
Donald D. Anderson, Patrick J. Stover
PLoS One. 2009; 4(6): e5839. Published online 2009 Jun 9. doi: 10.1371/journal.pone.0005839
PMCID:
PMC2688753
AbstractArticlePDF–636K
20.
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells
Gwenn M. Hansen, Diane C. Markesich, Michael B. Burnett, Qichao Zhu, Karen M. Dionne, Lizabeth J. Richter, Richard H. Finnell, Arthur T. Sands, Brian P. Zambrowicz, Alejandro Abuin
Genome Res. 2008 Oct; 18(10): 1670–1679. doi: 10.1101/gr.078352.108
PMCID:
PMC2556270
AbstractArticlePDF–493K

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