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Select item 113818381.

Etomoxir repurposed as a promiscuous fatty acid mimetic chemoproteomic probe

Joseph Choi, Danielle M. Smith, Ye Jin Lee, Danfeng Cai, Mohammad J. Hossain, Tamara J. O’Connor, Pragney Deme, Norman J. Haughey, Susanna Scafidi, Ryan C. Riddle, Michael J. Wolfgang

iScience. 2024 Sep 20; 27(9): 110642. Published online 2024 Aug 2. doi: 10.1016/j.isci.2024.110642

PMCID:: PMC11381838

Abstract Article PDF–5.1M

Select item 112428642.

Skeletal Muscle UCHL1 Negatively Regulates Muscle Development and Recovery after Muscle Injury

Ryan Antony, Katherine Aby, Morgan Montgomery, Yifan Li

Int J Mol Sci. 2024 Jul; 25(13): 7330. Published online 2024 Jul 4. doi: 10.3390/ijms25137330

PMCID:: PMC11242864

Abstract Article PDF–5.6M

Select item 112177833.

Thbs1 regulates skeletal muscle mass in a TGFβ-Smad2/3-ATF4-dependent manner

Davy Vanhoutte, Tobias G. Schips, Rachel A. Minerath, Jiuzhou Huo, Naga Swathi Sree Kavuri, Vikram Prasad, Suh-Chin Lin, Michael J. Bround, Michelle A. Sargent, Christopher M. Adams, Jeffery D. Molkentin

Cell Rep. Author manuscript; available in PMC 2024 Jul 2.

Published in final edited form as: Cell Rep. 2024 May 28; 43(5): 114149. Published online 2024 Apr 26. doi: 10.1016/j.celrep.2024.114149

PMCID:: PMC11217783

Abstract Article PDF–3.2M

Select item 107882694.

Epigenetic repression of Cend1 by lysine-specific demethylase 1 is essential for murine heart development

Huahua Liu, Rui Zhou, Shanshan Li, Jinling Dong, Yuan Fang, Yuru Luo, Hongyu Su, Baochang Lai, Lingli Liang, Donghong Zhang, Yanmin Zhang, John Y-J. Shyy, Bin Zhou, Zuyi Yuan, Yidong Wang

iScience. 2024 Jan 19; 27(1): 108722. Published online 2023 Dec 13. doi: 10.1016/j.isci.2023.108722

PMCID:: PMC10788269

Abstract Article PDF–11M

Select item 105631385.

Regulatory T cells require IL6 receptor alpha signaling to control skeletal muscle function and regeneration

Maike Becker, Sini S. Joseph, Francisco Garcia-Carrizo, Robby Z. Tom, Daria Opaleva, Isabelle Serr, Matthias H. Tschöp, Tim J. Schulz, Susanna M. Hofmann, Carolin Daniel

Cell Metab. 2023 Oct 3; 35(10): 1736–1751.e7. doi: 10.1016/j.cmet.2023.08.010

PMCID:: PMC10563138

Abstract Article

Select item 104568526.

ANT-dependent MPTP underlies necrotic myofiber death in muscular dystrophy

Michael J. Bround, Julian R. Havens, Allen J. York, Michelle A. Sargent, Jason Karch, Jeffery D. Molkentin

Sci Adv. 2023 Aug; 9(34): eadi2767. Published online 2023 Aug 25. doi: 10.1126/sciadv.adi2767

PMCID:: PMC10456852

Abstract Article PDF–1.2M

Select item 103986727.

PRMT5 links lipid metabolism to contractile function of skeletal muscles

Kun Ho Kim, Zhihao Jia, Madigan Snyder, Jingjuan Chen, Jiamin Qiu, Stephanie N Oprescu, Xiyue Chen, Sabriya A Syed, Feng Yue, Bruno T Roseguini, Anthony N Imbalzano, Changdeng Hu, Shihuan Kuang

EMBO Rep. 2023 Aug; 24(8): e57306. Published online 2023 Jun 19. doi: 10.15252/embr.202357306

PMCID:: PMC10398672

Abstract Article PDF–4.0M

Select item 103904928.

Three-dimensional molecular architecture of mouse organogenesis

Fangfang Qu, Wenjia Li, Jian Xu, Ruifang Zhang, Jincan Ke, Xiaodie Ren, Xiaogao Meng, Lexin Qin, Jingna Zhang, Fangru Lu, Xin Zhou, Xi Luo, Zhen Zhang, Minhan Wang, Guangming Wu, Duanqing Pei, Jiekai Chen, Guizhong Cui, Shengbao Suo, Guangdun Peng

Nat Commun. 2023; 14: 4599. Published online 2023 Jul 31. doi: 10.1038/s41467-023-40155-7

PMCID:: PMC10390492

Abstract Article PDF–13M

Select item 103315819.

A coordinated multiorgan metabolic response contributes to human mitochondrial myopathy

Nneka Southwell, Guido Primiano, Viraj Nadkarni, Nabeel Attarwala, Emelie Beattie, Dawson Miller, Sumaitaah Alam, Irene Liparulo, Yevgeniya I Shurubor, Maria Lucia Valentino, Valerio Carelli, Serenella Servidei, Steven S Gross, Giovanni Manfredi, Qiuying Chen, Marilena D'Aurelio

EMBO Mol Med. 2023 Jul; 15(7): e16951. Published online 2023 May 24. doi: 10.15252/emmm.202216951

PMCID:: PMC10331581

Abstract Article PDF–4.5M

Select item 1026752010.

Hes1 marks peri-condensation mesenchymal cells that generate both chondrocytes and perichondrial cells in early bone development

Yuki Matsushita, Hiroaki Manabe, Takahiro Ohyama, Shogo Nakamura, Mizuki Nagata, Wanida Ono, Noriaki Ono

J Biol Chem. 2023 Jun; 299(6): 104805. Published online 2023 May 11. doi: 10.1016/j.jbc.2023.104805

PMCID:: PMC10267520

Abstract Article PDF–7.3M

Select item 1025055511.

Myofiber Baf60c controls muscle regeneration by modulating Dkk3-mediated paracrine signaling

Jingya Xu, Xiaofei Li, Wei Chen, Ziyin Zhang, Yanping Zhou, Yahui Gou, Cheng-an Lv, Lu Jin, Xinyuan Qiu, Shengshan Ma, Qing-Qian Wu, Tongyu Liu, Lin Mi, Zhuoying Yang, Ting Yu, Xiaowen Pan, Yu Feng, Pengfei Shan, Zhuo-Xian Meng

J Exp Med. 2023 Sep 4; 220(9): e20221123. Published online 2023 Jun 7. doi: 10.1084/jem.20221123

PMCID:: PMC10250555

Abstract Article PDF–10M

Select item 998168712.

MYTHO is a novel regulator of skeletal muscle autophagy and integrity

Jean-Philippe Leduc-Gaudet, Anais Franco-Romero, Marina Cefis, Alaa Moamer, Felipe E. Broering, Giulia Milan, Roberta Sartori, Tomer Jordi Chaffer, Maude Dulac, Vincent Marcangeli, Dominique Mayaki, Laurent Huck, Anwar Shams, José A. Morais, Elise Duchesne, Hanns Lochmuller, Marco Sandri, Sabah N. A. Hussain, Gilles Gouspillou

Nat Commun. 2023; 14: 1199. Published online 2023 Mar 2. doi: 10.1038/s41467-023-36817-1

PMCID:: PMC9981687

Abstract Article PDF–13M

Select item 994291513.

Sarcopenia phenotype and impaired muscle function in male mice with fast-twitch muscle-specific knockout of the androgen receptor

Tatsuya Hosoi, Mitsutaka Yakabe, Hiroko Sasakawa, Takayoshi Sasako, Kohjiro Ueki, Shigeaki Kato, Suzumi M. Tokuoka, Yoshiya Oda, Masahiro Abe, Toshio Matsumoto, Masahiro Akishita, Sumito Ogawa

Proc Natl Acad Sci U S A. 2023 Jan 24; 120(4): e2218032120. Published online 2023 Jan 20. doi: 10.1073/pnas.2218032120

PMCID:: PMC9942915

Abstract Article PDF–838K

Select item 981238414.

Lactate metabolism is essential in early-onset mitochondrial myopathy

Zhenkang Chen, Bogdan Bordieanu, Rushendhiran Kesavan, Nicholas P. Lesner, Siva Sai Krishna Venigalla, Spencer D. Shelton, Ralph J. DeBerardinis, Prashant Mishra

Sci Adv. 2023 Jan; 9(1): eadd3216. Published online 2023 Jan 4. doi: 10.1126/sciadv.add3216

PMCID:: PMC9812384

Abstract Article PDF–2.8M

Select item 972002015.

Enzymatically dissociated muscle fibers display rapid dedifferentiation and impaired mitochondrial calcium control

Charlotte Gineste, Sonia Youhanna, Sabine U. Vorrink, Sara Henriksson, Andrés Hernández, Arthur J. Cheng, Thomas Chaillou, Andreas Buttgereit, Dominik Schneidereit, Oliver Friedrich, Kjell Hultenby, Joseph D. Bruton, Niklas Ivarsson, Linda Sandblad, Volker M. Lauschke, Håkan Westerblad

iScience. 2022 Dec 22; 25(12): 105654. Published online 2022 Nov 22. doi: 10.1016/j.isci.2022.105654

PMCID:: PMC9720020

Abstract Article PDF–5.2M

Select item 963008716.

Obese Skeletal Muscle–Expressed Interferon Regulatory Factor 4 Transcriptionally Regulates Mitochondrial Branched-Chain Aminotransferase Reprogramming Metabolome

Ting Yao, Hongmei Yan, Xiaopeng Zhu, Qiongyue Zhang, Xingyu Kong, Shanshan Guo, Yonghao Feng, Hui Wang, Yinghui Hua, Jing Zhang, Steven D. Mittelman, Peter Tontonoz, Zhenqi Zhou, Tiemin Liu, Xingxing Kong

Diabetes. 2022 Nov; 71(11): 2256–2271. Published online 2022 Jun 17. doi: 10.2337/db22-0260

Correction in:: Diabetes. 2023 Feb; 72(2): 309.

PMCID:: PMC9630087

Abstract Article PDF–3.4M

Select item 955312317.

Developmental heterogeneity of embryonic neuroendocrine chromaffin cells and their maturation dynamics

Natalia Akkuratova, Louis Faure, Polina Kameneva, Maria Eleni Kastriti, Igor Adameyko

Front Endocrinol (Lausanne) 2022; 13: 1020000. Published online 2022 Sep 27. doi: 10.3389/fendo.2022.1020000

PMCID:: PMC9553123

Abstract Article PDF–28M

Select item 953500818.

Deletion of skeletal muscle Akt1/2 causes osteosarcopenia and reduces lifespan in mice

Takayoshi Sasako, Toshihiro Umehara, Kotaro Soeda, Kazuma Kaneko, Miho Suzuki, Naoki Kobayashi, Yukiko Okazaki, Miwa Tamura-Nakano, Tomoki Chiba, Domenico Accili, C. Ronald Kahn, Tetsuo Noda, Hiroshi Asahara, Toshimasa Yamauchi, Takashi Kadowaki, Kohjiro Ueki

Nat Commun. 2022; 13: 5655. Published online 2022 Oct 5. doi: 10.1038/s41467-022-33008-2

PMCID:: PMC9535008

Abstract Article PDF–3.1M

Select item 943472419.

Ambra1 deficiency impairs mitophagy in skeletal muscle

Lisa Gambarotto, Samuele Metti, Martina Chrisam, Cristina Cerqua, Patrizia Sabatelli, Andrea Armani, Carlo Zanon, Marianna Spizzotin, Silvia Castagnaro, Flavie Strappazzon, Paolo Grumati, Matilde Cescon, Paola Braghetta, Eva Trevisson, Francesco Cecconi, Paolo Bonaldo

J Cachexia Sarcopenia Muscle. 2022 Aug; 13(4): 2211–2224. Published online 2022 May 20. doi: 10.1002/jcsm.13010