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Select item 114570661.

Hypomorphic mutation in the large subunit of replication protein A affects mutagenesis by human APOBEC cytidine deaminases in yeast

Matthew S Dennen, Zachary W Kockler, Steven A Roberts, Adam B Burkholder, Leszek J Klimczak, Dmitry A Gordenin

G3 (Bethesda) 2024 Oct; 14(10): jkae196. Published online 2024 Aug 16. doi: 10.1093/g3journal/jkae196

PMCID:: PMC11457066

Abstract Article PDF–1.3M

Select item 113624592.

The novel ribosome biogenesis inhibitor usnic acid blocks nucleolar pre-60S maturation

Lisa Kofler, Lorenz Grundmann, Magdalena Gerhalter, Michael Prattes, Juliane Merl-Pham, Gertrude Zisser, Irina Grishkovskaya, Victor-Valentin Hodirnau, Martin Vareka, Rolf Breinbauer, Stefanie M. Hauck, David Haselbach, Helmut Bergler

Nat Commun. 2024; 15: 7511. Published online 2024 Aug 29. doi: 10.1038/s41467-024-51754-3

PMCID:: PMC11362459

Abstract Article PDF–3.5M

Select item 111048493.

Characterization of the dimeric CMG/pre-initiation complex and its transition into DNA replication forks

Lu Liu, Yue Zhang, Jingjing Zhang, Jian-Hua Wang, Qinhong Cao, Zhen Li, Judith L. Campbell, Meng-Qiu Dong, Huiqiang Lou

Cell Mol Life Sci. 2020 Aug; 77(15): 3041–3058. Published online 2019 Nov 15. doi: 10.1007/s00018-019-03333-9

PMCID:: PMC11104849

Abstract Article PDF–9.1M

Select item 110457244.

Replication protein-A, RPA, plays a pivotal role in the maintenance of recombination checkpoint in yeast meiosis

Arivarasan Sampathkumar, Chen Zhong, Yuting Tang, Yurika Fujita, Masaru Ito, Akira Shinohara

Sci Rep. 2024; 14: 9550. Published online 2024 Apr 25. doi: 10.1038/s41598-024-60082-x

PMCID:: PMC11045724

Abstract Article PDF–2.2M

Select item 110401555.

RPA interacts with Rad52 to promote meiotic crossover and noncrossover recombination

Jeong H Joo, Soogil Hong, Mika T Higashide, Eui-Hwan Choi, Seobin Yoon, Min-Su Lee, Hyun Ah Kang, Akira Shinohara, Nancy Kleckner, Keun P Kim

Nucleic Acids Res. 2024 Apr 24; 52(7): 3794–3809. Published online 2024 Feb 10. doi: 10.1093/nar/gkae083

PMCID:: PMC11040155

Abstract Article PDF–4.6M

Select item 110241856.

The DEAD-box ATPase Dbp10/DDX54 initiates peptidyl transferase center formation during 60S ribosome biogenesis

Victor E. Cruz, Christine S. Weirich, Nagesh Peddada, Jan P. Erzberger

Nat Commun. 2024; 15: 3296. Published online 2024 Apr 17. doi: 10.1038/s41467-024-47616-7

PMCID:: PMC11024185

Abstract Article PDF–7.4M

Select item 110149097.

The functional significance of the RPA- and PCNA-dependent recruitment of Pif1 to DNA

Oleksii Kotenko, Svetlana Makovets

EMBO Rep. 2024 Apr; 25(4): 1734–1751. Published online 2024 Mar 13. doi: 10.1038/s44319-024-00114-9

PMCID:: PMC11014909

Abstract Article PDF–1.2M

Select item 108724778.

Protein interaction network revealed by quantitative proteomic analysis links TFIIB to multiple aspects of the transcription cycle

Michael J. O’Brien, Athar Ansari

Biochim Biophys Acta Proteins Proteom. Author manuscript; available in PMC 2024 Feb 16.

Published in final edited form as: Biochim Biophys Acta Proteins Proteom. 2024 Jan 1; 1872(1): 140968. Published online 2023 Oct 19. doi: 10.1016/j.bbapap.2023.140968

PMCID:: PMC10872477

Abstract Article PDF–1.7M

Select item 108687279.

Adaptive preservation of orphan ribosomal proteins in chaperone-dispersed condensates

Asif Ali, Rania Garde, Olivia C. Schaffer, Jared A. M. Bard, Kabir Husain, Samantha Keyport Kik, Kathleen A. Davis, Sofia Luengo-Woods, Maya G. Igarashi, D. Allan Drummond, Allison H. Squires, David Pincus

Nat Cell Biol. Author manuscript; available in PMC 2024 Feb 15.

Published in final edited form as: Nat Cell Biol. 2023 Nov; 25(11): 1691–1703. Published online 2023 Oct 16. doi: 10.1038/s41556-023-01253-2

PMCID:: PMC10868727

Abstract Article PDF–7.0M

Select item 1070013810.

The social and structural architecture of the yeast protein interactome

André C. Michaelis, Andreas-David Brunner, Maximilian Zwiebel, Florian Meier, Maximilian T. Strauss, Isabell Bludau, Matthias Mann

Nature. 2023; 624(7990): 192–200. Published online 2023 Nov 15. doi: 10.1038/s41586-023-06739-5

PMCID:: PMC10700138

Abstract Article PDF–20M

Select item 1068125911.

eIF2A represses cell wall biogenesis gene expression in Saccharomyces cerevisiae

Laura Meyer, Baptiste Courtin, Maïté Gomard, Abdelkader Namane, Emmanuelle Permal, Gwenael Badis, Alain Jacquier, Micheline Fromont-Racine

PLoS One. 2023; 18(11): e0293228. Published online 2023 Nov 27. doi: 10.1371/journal.pone.0293228

PMCID:: PMC10681259

Abstract Article PDF–2.5M

Select item 1051664212.

ISW1a modulates cohesin distribution in centromeric and pericentromeric regions

Ireneusz Litwin, Małgorzata Nowicka, Katarzyna Markowska, Ewa Maciaszczyk-Dziubińska, Paulina Tomaszewska, Robert Wysocki, Karol Kramarz

Nucleic Acids Res. 2023 Sep 22; 51(17): 9101–9121. Published online 2023 Jul 24. doi: 10.1093/nar/gkad612

PMCID:: PMC10516642

Abstract Article PDF–2.8M

Select item 1048021413.

The COMPASS subunit Spp1 protects nascent DNA at the Tus/Ter replication fork barrier by limiting DNA availability to nucleases

Nagham Ghaddar, Yves Corda, Pierre Luciano, Martina Galli, Ylli Doksani, Vincent Géli

Nat Commun. 2023; 14: 5430. Published online 2023 Sep 5. doi: 10.1038/s41467-023-41100-4

PMCID:: PMC10480214

Abstract Article PDF–2.4M

Select item 1028790514.

Proper RPA acetylation promotes accurate DNA replication and repair

Xiaoli Gan, Yueyue Zhang, Donghao Jiang, Jingyao Shi, Han Zhao, Chengyu Xie, Yanyan Wang, Jingyan Xu, Xinghua Zhang, Gang Cai, Hailong Wang, Jun Huang, Xuefeng Chen

Nucleic Acids Res. 2023 Jun 23; 51(11): 5565–5583. Published online 2023 May 4. doi: 10.1093/nar/gkad291

PMCID:: PMC10287905

Abstract Article PDF–3.3M

Select item 1023336815.

A systematic proximity ligation approach to studying protein‐substrate specificity identifies the substrate spectrum of the Ssh1 translocon

Nir Cohen, Naama Aviram, Maya Schuldiner

EMBO J. 2023 Jun; 42(11): e113385. Published online 2023 Apr 19. doi: 10.15252/embj.2022113385

PMCID:: PMC10233368

Abstract Article PDF–1.2M

Select item 1021305016.

Bre1/RNF20 promotes Rad51-mediated strand exchange and antagonizes the Srs2/FBH1 helicases

Guangxue Liu, Jimin Li, Boxue He, Jiaqi Yan, Jingyu Zhao, Xuejie Wang, Xiaocong Zhao, Jingyan Xu, Yeyao Wu, Simin Zhang, Xiaoli Gan, Chun Zhou, Xiangpan Li, Xinghua Zhang, Xuefeng Chen

Nat Commun. 2023; 14: 3024. Published online 2023 May 25. doi: 10.1038/s41467-023-38617-z

PMCID:: PMC10213050

Abstract Article PDF–1.3M

Select item 1008355517.

A DNA damage–induced phosphorylation circuit enhances Mec1^ATR Ddc2^ATRIP recruitment to Replication Protein A

Luke A. Yates, Elias A. Tannous, R. Marc Morgan, Peter M. Burgers, Xiaodong Zhang

Proc Natl Acad Sci U S A. 2023 Apr 4; 120(14): e2300150120. Published online 2023 Mar 30. doi: 10.1073/pnas.2300150120

PMCID:: PMC10083555

Abstract Article PDF–2.3M

Select item 967335218.

A proteomic screen of Ty1 integrase partners identifies the protein kinase CK2 as a regulator of Ty1 retrotransposition

Anastasia Barkova, Indranil Adhya, Christine Conesa, Amna Asif-Laidin, Amandine Bonnet, Elise Rabut, Carine Chagneau, Pascale Lesage, Joël Acker

Mob DNA. 2022; 13: 26. Published online 2022 Nov 18. doi: 10.1186/s13100-022-00284-0

PMCID:: PMC9673352

Abstract Article PDF–2.6M

Select item 944012319.

Rtt105 regulates RPA function by configurationally stapling the flexible domains

Sahiti Kuppa, Jaigeeth Deveryshetty, Rahul Chadda, Jenna R. Mattice, Nilisha Pokhrel, Vikas Kaushik, Angela Patterson, Nalini Dhingra, Sushil Pangeni, Marisa K. Sadauskas, Sajad Shiekh, Hamza Balci, Taekjip Ha, Xiaolan Zhao, Brian Bothner, Edwin Antony

Nat Commun. 2022; 13: 5152. Published online 2022 Sep 2. doi: 10.1038/s41467-022-32860-6