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Items: 1 to 20 of 222

1.
The fork protection complex generates DNA topological stress–induced DNA damage while ensuring full and faithful genome duplication
Andrea Keszthelyi, Sahar Mansoubi, Alex Whale, Jonathan Houseley, Jonathan Baxter
Proc Natl Acad Sci U S A. 2024 Dec 3; 121(49): e2413631121. Published online 2024 Nov 26. doi: 10.1073/pnas.2413631121
PMCID:
PMC11626154
ArticlePDF–2.2M
2.
Stabilization of expandable DNA repeats by the replication factor Mcm10 promotes cell viability
Chiara Masnovo, Zohar Paleiov, Daniel Dovrat, Laurel K. Baxter, Sofia Movafaghi, Amir Aharoni, Sergei M. Mirkin
Nat Commun. 2024; 15: 10532. Published online 2024 Dec 3. doi: 10.1038/s41467-024-54977-6
PMCID:
PMC11615337
ArticlePDF–3.5M
3.
Protein interaction network revealed by quantitative proteomic analysis links TFIIB to multiple aspects of the transcription cycle
Michael J. O’Brien, Athar Ansari
Biochim Biophys Acta Proteins Proteom. Author manuscript; available in PMC 2024 Feb 16.
Published in final edited form as: Biochim Biophys Acta Proteins Proteom. 2024 Jan 1; 1872(1): 140968. Published online 2023 Oct 19. doi: 10.1016/j.bbapap.2023.140968
PMCID:
PMC10872477
ArticlePDF–1.7M
4.
The social and structural architecture of the yeast protein interactome
André C. Michaelis, Andreas-David Brunner, Maximilian Zwiebel, Florian Meier, Maximilian T. Strauss, Isabell Bludau, Matthias Mann
Nature. 2023; 624(7990): 192–200. Published online 2023 Nov 15. doi: 10.1038/s41586-023-06739-5
PMCID:
PMC10700138
ArticlePDF–20M
5.
Checkpoint kinase interaction with DNA polymerase alpha regulates replication progression during stress
Andreas Hadjicharalambous, Alex J. Whale, Geylani Can, J. Mark Skehel, Jonathan M. Houseley, Philip Zegerman
Version 1. Wellcome Open Res. 2023; 8: 327. Published online 2023 Jul 26. doi: 10.12688/wellcomeopenres.19617.1
PMCID:
PMC10521137
ArticlePDF–4.0M
6.
Replisome-cohesin interactions provided by the Tof1-Csm3 and Mrc1 cohesion establishment factors
Sudikchya Shrestha, Masashi Minamino, Zhuo A. Chen, Céline Bouchoux, Juri Rappsilber, Frank Uhlmann
Chromosoma. 2023; 132(2): 117–135. Published online 2023 May 11. doi: 10.1007/s00412-023-00797-4
PMCID:
PMC10247859
ArticlePDF–2.3M
7.
The conserved histone chaperone Spt6 is strongly required for DNA replication and genome stability
Catherine L.W. Miller, Fred Winston
Cell Rep. Author manuscript; available in PMC 2023 Apr 16.
Published in final edited form as: Cell Rep. 2023 Mar 28; 42(3): 112264. Published online 2023 Mar 15. doi: 10.1016/j.celrep.2023.112264
PMCID:
PMC10106089
ArticlePDF–1.3M
8.
Genetic requirements for repair of lesions caused by single genomic ribonucleotides in S phase
Natalie Schindler, Matthias Tonn, Vanessa Kellner, Jia Jun Fung, Arianna Lockhart, Olga Vydzhak, Thomas Juretschke, Stefanie Möckel, Petra Beli, Anton Khmelinskii, Brian Luke
Nat Commun. 2023; 14: 1227. Published online 2023 Mar 3. doi: 10.1038/s41467-023-36866-6
PMCID:
PMC9984532
ArticlePDF–3.0M
9.
A synthetic genetic array screen for interactions with the RNA helicase DED1 during cell stress in budding yeast
Sara B Carey, Hannah M List, Ashwin Siby, Paolo Guerra, Timothy A Bolger
G3 (Bethesda) 2023 Jan; 13(1): jkac296. Published online 2022 Nov 21. doi: 10.1093/g3journal/jkac296
PMCID:
PMC9836348
ArticlePDF–857K
10.
Complex mutation profiles in mismatch repair and ribonucleotide reductase mutants reveal novel repair substrate specificity of MutS homolog (MSH) complexes
Natalie A Lamb, Jonathan E Bard, Raphael Loll-Krippleber, Grant W Brown, Jennifer A Surtees
Genetics. 2022 Aug; 221(4): iyac092. Published online 2022 Jun 10. doi: 10.1093/genetics/iyac092
PMCID:
PMC9339293
ArticlePDF–7.9M
11.
Mediator recruits the cohesin loader Scc2 to RNA Pol II-transcribed genes and promotes sister chromatid cohesion
Mark Mattingly, Chris Seidel, Sofía Muñoz, Yan Hao, Ying Zhang, Zhihui Wen, Laurence Florens, Frank Uhlmann, Jennifer L. Gerton
Curr Biol. 2022 Jul 11; 32(13): 2884–2896.e6. doi: 10.1016/j.cub.2022.05.019
PMCID:
PMC9286023
Article
12.
An integrated model for termination of RNA polymerase III transcription
Juanjuan Xie, Umberto Aiello, Yves Clement, Nouhou Haidara, Mathias Girbig, Jana Schmitzova, Vladimir Pena, Christoph W. Müller, Domenico Libri, Odil Porrua
Sci Adv. 2022 Jul; 8(28): eabm9875. Published online 2022 Jul 13. doi: 10.1126/sciadv.abm9875
PMCID:
PMC9278858
ArticlePDF–3.3M
13.
New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources
Stacia R Engel, Edith D Wong, Robert S Nash, Suzi Aleksander, Micheal Alexander, Eric Douglass, Kalpana Karra, Stuart R Miyasato, Matt Simison, Marek S Skrzypek, Shuai Weng, J Michael Cherry
Genetics. 2022 Apr; 220(4): iyab224. Published online 2021 Dec 13. doi: 10.1093/genetics/iyab224
PMCID:
PMC9209811
ArticlePDF–818K
14.
Chl1 helicase controls replication fork progression by regulating dNTP pools
Amandine Batté, Sophie C van der Horst, Mireille Tittel-Elmer, Su Ming Sun, Sushma Sharma, Jolanda van Leeuwen, Andrei Chabes, Haico van Attikum
Life Sci Alliance. 2022 Apr; 5(4): e202101153. Published online 2022 Jan 11. doi: 10.26508/lsa.202101153
PMCID:
PMC8761496
ArticlePDF–2.5M
15.
VID22 counteracts G-quadruplex-induced genome instability
Elena Galati, Maria C Bosio, Daniele Novarina, Matteo Chiara, Giulia M Bernini, Alessandro M Mozzarelli, Maria L García-Rubio, Belén Gómez-González, Andrés Aguilera, Thomas Carzaniga, Marco Todisco, Tommaso Bellini, Giulia M Nava, Gianmaria Frigè, Sarah Sertic, David S Horner, Anastasia Baryshnikova, Caterina Manzari, Anna M D’Erchia, Graziano Pesole, Grant W Brown, Marco Muzi-Falconi, Federico Lazzaro
Nucleic Acids Res. 2021 Dec 16; 49(22): 12785–12804. Published online 2021 Dec 6. doi: 10.1093/nar/gkab1156
PMCID:
PMC8682794
ArticlePDF–8.0M
16.
Elongating RNA polymerase II and RNA:DNA hybrids hinder fork progression and gene expression at sites of head-on replication-transcription collisions
Luca Zardoni, Eleonora Nardini, Alessandra Brambati, Chiara Lucca, Ramveer Choudhary, Federica Loperfido, Simone Sabbioneda, Giordano Liberi
Nucleic Acids Res. 2021 Dec 16; 49(22): 12769–12784. Published online 2021 Dec 8. doi: 10.1093/nar/gkab1146
PMCID:
PMC8682787
ArticlePDF–8.6M
17.
A regulatory phosphorylation site on Mec1 controls chromatin occupancy of RNA polymerases during replication stress
Verena Hurst, Kiran Challa, Felix Jonas, Romain Forey, Ragna Sack, Jan Seebacher, Christoph D Schmid, Naama Barkai, Kenji Shimada, Susan M Gasser, Jérôme Poli
EMBO J. 2021 Nov 2; 40(21): e108439. Published online 2021 Sep 27. doi: 10.15252/embj.2021108439
PMCID:
PMC8561635
ArticlePDF–6.1M
18.
A mechanism for Rad53 to couple leading- and lagging-strand DNA synthesis under replication stress in budding yeast
Albert Serra-Cardona, Chuanhe Yu, Xinmin Zhang, Xu Hua, Yuan Yao, Jiaqi Zhou, Haiyun Gan, Zhiguo Zhang
Proc Natl Acad Sci U S A. 2021 Sep 21; 118(38): e2109334118. Published online 2021 Sep 16. doi: 10.1073/pnas.2109334118
PMCID:
PMC8463864
ArticlePDF–1.7M
19.
Investigation of RNA metabolism through large-scale genetic interaction profiling in yeast
Laurence Decourty, Christophe Malabat, Emmanuel Frachon, Alain Jacquier, Cosmin Saveanu
Nucleic Acids Res. 2021 Sep 7; 49(15): 8535–8555. Published online 2021 Aug 6. doi: 10.1093/nar/gkab680
PMCID:
PMC8421204
ArticlePDF–2.9M
20.
Rad53 checkpoint kinase regulation of DNA replication fork rate via Mrc1 phosphorylation
Allison W McClure, John FX Diffley
eLife. 2021; 10: e69726. Published online 2021 Aug 13. doi: 10.7554/eLife.69726
PMCID:
PMC8387023
ArticlePDF–4.9M

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