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Select item 112511561.

Multi-step control of homologous recombination via Mec1/ATR suppresses chromosomal rearrangements

Bokun Xie, Ethan James Sanford, Shih-Hsun Hung, Mateusz Wagner, Wolf-Dietrich Heyer, Marcus B Smolka

EMBO J. 2024 Jul; 43(14): 3027–3043. Published online 2024 Jun 5. doi: 10.1038/s44318-024-00139-9

PMCID:: PMC11251156

Abstract Article PDF–3.1M

Select item 107096522.

The separation pin distinguishes the pro– and anti–recombinogenic functions of Saccharomyces cerevisiae Srs2

Aviv Meir, Vivek B. Raina, Carly E. Rivera, Léa Marie, Lorraine S. Symington, Eric C. Greene

Nat Commun. 2023; 14: 8144. Published online 2023 Dec 8. doi: 10.1038/s41467-023-43918-4

PMCID:: PMC10709652

Abstract Article PDF–3.8M

Select item 107001383.

The social and structural architecture of the yeast protein interactome

André C. Michaelis, Andreas-David Brunner, Maximilian Zwiebel, Florian Meier, Maximilian T. Strauss, Isabell Bludau, Matthias Mann

Nature. 2023; 624(7990): 192–200. Published online 2023 Nov 15. doi: 10.1038/s41586-023-06739-5

PMCID:: PMC10700138

Abstract Article PDF–20M

Select item 106813124.

Checkpoint phosphorylation sites on budding yeast Rif1 protect nascent DNA from degradation by Sgs1-Dna2

Vamsi Krishna Gali, Chandre Monerawela, Yassine Laksir, Shin-ichiro Hiraga, Anne D. Donaldson

PLoS Genet. 2023 Nov; 19(11): e1011044. Published online 2023 Nov 13. doi: 10.1371/journal.pgen.1011044

PMCID:: PMC10681312

Abstract Article PDF–3.2M

Select item 105700195.

Recombinase-independent chromosomal rearrangements between dispersed inverted repeats in Saccharomyces cerevisiae meiosis

Rachal M Allison, Dominic J Johnson, Matthew J Neale, Stephen Gray

Nucleic Acids Res. 2023 Oct 13; 51(18): 9703–9715. Published online 2023 Aug 7. doi: 10.1093/nar/gkad650

PMCID:: PMC10570019

Abstract Article PDF–3.6M

Select item 105503216.

Mitochondrial superoxide dismutase Sod2 suppresses nuclear genome instability during oxidative stress

Sonia Vidushi Gupta, Lillian Campos, Kristina Hildegard Schmidt

Genetics. 2023 Oct; 225(2): iyad147. Published online 2023 Aug 29. doi: 10.1093/genetics/iyad147

PMCID:: PMC10550321

Abstract Article PDF–1.2M

Select item 104000787.

Long-range DNA end resection supports homologous recombination by checkpoint activation rather than extensive homology generation

Michael T Kimble, Matthew J Johnson, Mattie R Nester, Lorraine S Symington

eLife. 2023; 12: e84322. Published online 2023 Jun 30. doi: 10.7554/eLife.84322

PMCID:: PMC10400078

Abstract Article PDF–3.7M

Select item 103298748.

Tolerance to replication stress requires Dun1p kinase and activation of the electron transport chain

Shreya Nagar, Riddhi Mehta, Pritpal Kaur, Roshini T. Liliah, Ales Vancura

Biochim Biophys Acta Mol Cell Res. Author manuscript; available in PMC 2024 Jan 1.

Published in final edited form as: Biochim Biophys Acta Mol Cell Res. 2023 Jan; 1870(1): 119382. Published online 2022 Oct 23. doi: 10.1016/j.bbamcr.2022.119382

PMCID:: PMC10329874

Abstract Article PDF–1.9M

Select item 103083739.

Ubx5‐Cdc48 assists the protease Wss1 at DNA‐protein crosslink sites in yeast

Audrey Noireterre, Nataliia Serbyn, Ivona Bagdiul, Françoise Stutz

EMBO J. 2023 Jul; 42(13): e113609. Published online 2023 May 5. doi: 10.15252/embj.2023113609

PMCID:: PMC10308373

Abstract Article PDF–8.0M

Select item 998453210.

Genetic requirements for repair of lesions caused by single genomic ribonucleotides in S phase

Natalie Schindler, Matthias Tonn, Vanessa Kellner, Jia Jun Fung, Arianna Lockhart, Olga Vydzhak, Thomas Juretschke, Stefanie Möckel, Petra Beli, Anton Khmelinskii, Brian Luke

Nat Commun. 2023; 14: 1227. Published online 2023 Mar 3. doi: 10.1038/s41467-023-36866-6

PMCID:: PMC9984532

Abstract Article PDF–3.0M

Select item 997687711.

The Ku complex promotes DNA end-bridging and this function is antagonized by Tel1/ATM kinase

Carlo Rinaldi, Paolo Pizzul, Erika Casari, Marco Mangiagalli, Renata Tisi, Maria Pia Longhese

Nucleic Acids Res. 2023 Feb 28; 51(4): 1783–1802. Published online 2023 Feb 10. doi: 10.1093/nar/gkad062

PMCID:: PMC9976877

Abstract Article PDF–6.3M

Select item 983634812.

A synthetic genetic array screen for interactions with the RNA helicase DED1 during cell stress in budding yeast

Sara B Carey, Hannah M List, Ashwin Siby, Paolo Guerra, Timothy A Bolger

G3 (Bethesda) 2023 Jan; 13(1): jkac296. Published online 2022 Nov 21. doi: 10.1093/g3journal/jkac296

PMCID:: PMC9836348

Abstract Article PDF–857K

Select item 924317613.

Multifaceted regulation of the sumoylation of the Sgs1 DNA helicase

Shibai Li, Ashley Mutchler, Xinji Zhu, Stephen So, John Epps, Danying Guan, Xiaolan Zhao, Xiaoyu Xue

J Biol Chem. 2022 Jul; 298(7): 102092. Published online 2022 May 30. doi: 10.1016/j.jbc.2022.102092

PMCID:: PMC9243176

Abstract Article PDF–1.6M

Select item 920981114.

New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources

Stacia R Engel, Edith D Wong, Robert S Nash, Suzi Aleksander, Micheal Alexander, Eric Douglass, Kalpana Karra, Stuart R Miyasato, Matt Simison, Marek S Skrzypek, Shuai Weng, J Michael Cherry

Genetics. 2022 Apr; 220(4): iyab224. Published online 2021 Dec 13. doi: 10.1093/genetics/iyab224

PMCID:: PMC9209811

Abstract Article PDF–818K

Select item 911754615.

Nej1 interacts with Sae2 at DNA double-stranded breaks to inhibit DNA resection

Aditya Mojumdar, Nancy Adam, Jennifer A. Cobb

J Biol Chem. 2022 Jun; 298(6): 101937. Published online 2022 Apr 13. doi: 10.1016/j.jbc.2022.101937

PMCID:: PMC9117546

Abstract Article PDF–2.7M

Select item 868275616.

Mapping yeast mitotic 5′ resection at base resolution reveals the sequence and positional dependence of nucleases in vivo

Dominic Bazzano, Stephanie Lomonaco, Thomas E Wilson

Nucleic Acids Res. 2021 Dec 16; 49(22): 12607–12621. Published online 2021 Jul 15. doi: 10.1093/nar/gkab597

PMCID:: PMC8682756

Abstract Article PDF–4.9M

Select item 856163517.

A regulatory phosphorylation site on Mec1 controls chromatin occupancy of RNA polymerases during replication stress

Verena Hurst, Kiran Challa, Felix Jonas, Romain Forey, Ragna Sack, Jan Seebacher, Christoph D Schmid, Naama Barkai, Kenji Shimada, Susan M Gasser, Jérôme Poli

EMBO J. 2021 Nov 2; 40(21): e108439. Published online 2021 Sep 27. doi: 10.15252/embj.2021108439

PMCID:: PMC8561635

Abstract Article PDF–6.1M

Select item 846393218.

SGS1-SuOff rescues the mild methylmethane sulfonate sensitivity of srs2Δ cells in Saccharomyces cerevisiae

Belen Herce-Hagiwara, Yee Mon Thu

MicroPubl Biol. 2021; 2021: 10.17912/micropub.biology.000480. Published online 2021 Sep 24. doi: 10.17912/micropub.biology.000480

PMCID:: PMC8463932

Abstract Article PDF–999K

Select item 828479919.

NuA4 and SAGA acetyltransferase complexes cooperate for repair of DNA breaks by homologous recombination

Xue Cheng, Valérie Côté, Jacques Côté

PLoS Genet. 2021 Jul; 17(7): e1009459. Published online 2021 Jul 6. doi: 10.1371/journal.pgen.1009459

PMCID:: PMC8284799

Abstract Article PDF–2.1M

Select item 823765220.

Rtt105 promotes high-fidelity DNA replication and repair by regulating the single-stranded DNA-binding factor RPA

Xuejie Wang, Yang Dong, Xiaocong Zhao, Jinbao Li, Jordan Lee, Zhenxin Yan, Shuangshuang Yang, Wenqiang Wu, Ximiao Hou, Guangxue Liu, Yueyue Zhang, Lun Song, Gang Cai, Qing Li, Grzegorz Ira, Xinghua Zhang, Xuefeng Chen

Proc Natl Acad Sci U S A. 2021 Jun 22; 118(25): e2106393118. Published online 2021 Jun 17. doi: 10.1073/pnas.2106393118