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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 104761742.

Embryo‐uterine interaction coordinates mouse embryogenesis during implantation

Vladyslav Bondarenko, Mikhail Nikolaev, Dimitri Kromm, Roman Belousov, Adrian Wolny, Marloes Blotenburg, Peter Zeller, Saba Rezakhani, Johannes Hugger, Virginie Uhlmann, Lars Hufnagel, Anna Kreshuk, Jan Ellenberg, Alexander van Oudenaarden, Anna Erzberger, Matthias P Lutolf, Takashi Hiiragi

EMBO J. 2023 Sep; 42(17): e113280. Published online 2023 Jul 31. doi: 10.15252/embj.2022113280

PMCID:: PMC10476174

Abstract Article PDF–4.7M

Select item 103078523.

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility

Juan Gu, Pingyang Ke, Haokun Guo, Jing Liu, Yan Liu, Xin Tian, Zhuo Huang, Xin Xu, Demei Xu, Yuanlin Ma, Xuefeng Wang, Fei Xiao

Cell Death Differ. 2023 Jul; 30(7): 1726–1741. Published online 2023 May 4. doi: 10.1038/s41418-023-01174-5

PMCID:: PMC10307852

Abstract Article PDF–8.8M

Select item 102499504.

Rab11a Is Essential for the Development and Integrity of the Stereocilia and Kinocilia in the Mammalian Organ of Corti

Lindsey Knapp, Haojie Sun, Yan-Mei Wang, Bin-Jun Chen, Xi Lin, Nan Gao, Ping Chen, Dongdong Ren

eNeuro. 2023 Jun; 10(6): ENEURO.0420-22.2023. Prepublished online 2023 May 24. Published online 2023 Jun 2. doi: 10.1523/ENEURO.0420-22.2023

PMCID:: PMC10249950

Abstract Article PDF–5.0M

Select item 81001625.

Oocyte-derived microvilli control female fertility by optimizing ovarian follicle selection in mice

Yan Zhang, Ye Wang, Xie’an Feng, Shuo Zhang, Xueqiang Xu, Lingyu Li, Shudong Niu, Yingnan Bo, Chao Wang, Zhen Li, Guoliang Xia, Hua Zhang

Nat Commun. 2021; 12: 2523. Published online 2021 May 5. doi: 10.1038/s41467-021-22829-2

PMCID:: PMC8100162

Abstract Article PDF–11M

Select item 74159916.

BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)

Kou Motani, Hidetaka Kosako

J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323

PMCID:: PMC7415991

Abstract Article PDF–2.0M

Select item 70166077.

Finding the Unicorn, a New Mouse Model of Midfacial Clefting

Brandi Lantz, Casey White, Xinyun Liu, Yong Wan, George Gabriel, Cecilia W. Y. Lo, Heather L. Szabo-Rogers

Genes (Basel) 2020 Jan; 11(1): 83. Published online 2020 Jan 11. doi: 10.3390/genes11010083

PMCID:: PMC7016607

Abstract Article PDF–4.7M

Select item 66927708.

Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics

Joel D. Federspiel, Todd M. Greco, Krystal K. Lum, Ileana M. Cristea

Mol Cell Proteomics. 2019 Aug 9; 18(8 Suppl 1): S92–S113. Published online 2019 Apr 30. doi: 10.1074/mcp.RA118.001253

PMCID:: PMC6692770

Abstract Article PDF–7.7M

Select item 66746169.

The Chloride Intracellular Channel Protein CLIC5 Is Expressed at High Levels in Hair Cell Stereocilia and Is Essential for Normal Inner Ear Function

Leona H. Gagnon, Chantal M. Longo-Guess, Mark Berryman, Jung-Bum Shin, Katherine W. Saylor, Heping Yu, Peter G. Gillespie, Kenneth R. Johnson

J Neurosci. 2006 Oct 4; 26(40): 10188–10198. doi: 10.1523/JNEUROSCI.2166-06.2006

PMCID:: PMC6674616

Abstract Article PDF–766K

Select item 650659910.

VANGL2 regulates luminal epithelial organization and cell turnover in the mammary gland

Prestina Smith, Nathan Godde, Stefany Rubio, Melawit Tekeste, Eszter K. Vladar, Jeffrey D. Axelrod, Deborah J. Henderson, Michal Milgrom-Hoffman, Patrick O. Humbert, Lindsay Hinck

Sci Rep. 2019; 9: 7079. Published online 2019 May 8. doi: 10.1038/s41598-019-43444-8

PMCID:: PMC6506599

Abstract Article PDF–2.9M

Select item 626277711.

LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow

Hui-yuan Tseng, Anna V. Samarelli, Patricia Kammerer, Sarah Scholze, Tilman Ziegler, Roland Immler, Roy Zent, Markus Sperandio, Charles R. Sanders, Reinhard Fässler, Ralph T. Böttcher

J Cell Sci. 2018 Nov 15; 131(22): jcs218214. Published online 2018 Nov 21. doi: 10.1242/jcs.218214

PMCID:: PMC6262777

Abstract Article

Select item 578396512.

ELMOD1 Stimulates ARF6-GTP Hydrolysis to Stabilize Apical Structures in Developing Vestibular Hair Cells

Jocelyn F. Krey, Rachel A. Dumont, Philip A. Wilmarth, Larry L. David, Kenneth R. Johnson, Peter G. Barr-Gillespie

J Neurosci. 2018 Jan 24; 38(4): 843–857. doi: 10.1523/JNEUROSCI.2658-17.2017

PMCID:: PMC5783965

Abstract Article PDF–9.3M

Select item 566661713.

The BEACH protein LRBA is required for hair bundle maintenance in cochlear hair cells and for hearing

Christian Vogl, Tanvi Butola, Natja Haag, Torben J Hausrat, Michael G Leitner, Michel Moutschen, Philippe P Lefèbvre, Carsten Speckmann, Lillian Garrett, Lore Becker, Helmut Fuchs, Martin Hrabe de Angelis, Sandor Nietzsche, Michael M Kessels, Dominik Oliver, Matthias Kneussel, Manfred W Kilimann, Nicola Strenzke

EMBO Rep. 2017 Nov; 18(11): 2015–2029. Published online 2017 Sep 11. doi: 10.15252/embr.201643689

PMCID:: PMC5666617

Abstract Article PDF–7.3M

Select item 564508214.

Spatio-temporal profile of postynaptic interactomes integrates components of complex brain disorders

Jing Li, Wangshu Zhang, Hui Yang, Daniel P. Howrigan, Brent Wilkinson, Tade Souaiaia, Oleg V. Evgrafov, Giulio Genovese, Veronica A. Clementel, Jennifer C. Tudor, Ted Abel, James A. Knowles, Benjamin M. Neale, Kai Wang, Fengzhu Sun, Marcelo P. Coba

Nat Neurosci. Author manuscript; available in PMC 2018 Aug 1.

Published in final edited form as: Nat Neurosci. 2017 Aug; 20(8): 1150–1161. Published online 2017 Jun 26. doi: 10.1038/nn.4594

PMCID:: PMC5645082

Abstract Article PDF–2.3M

Select item 530005315.

The Apical Domain Is Required and Sufficient for the First Lineage Segregation in the Mouse Embryo

Ekaterina Korotkevich, Ritsuya Niwayama, Aurélien Courtois, Stefanie Friese, Nicolas Berger, Frank Buchholz, Takashi Hiiragi

Dev Cell. 2017 Feb 6; 40(3): 235–247.e7. doi: 10.1016/j.devcel.2017.01.006

PMCID:: PMC5300053

Abstract Article

Select item 529582116.

High-throughput discovery of novel developmental phenotypes

Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray

Nature. Author manuscript; available in PMC 2017 Mar 14.

Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356

Correction in:: Nature. 2017 Nov 16; 551(7680): 398.

PMCID:: PMC5295821

Abstract Article PDF–3.0M

Select item 526816817.

Crumbs2 Promotes Cell Ingression During the Epithelial-to-Mesenchymal Transition at Gastrulation

Nitya Ramkumar, Tatiana Omelchenko, Nancy F. Silva-Gagliardi, C. Jane McGlade, Jan Wijnholds, Kathryn V. Anderson

Nat Cell Biol. Author manuscript; available in PMC 2017 Dec 1.

Published in final edited form as: Nat Cell Biol. 2016 Dec; 18(12): 1281–1291. Published online 2016 Nov 21. doi: 10.1038/ncb3442

PMCID:: PMC5268168

Abstract Article PDF–3.4M

Select item 506552818.

Precise Somatotopic Thalamocortical Axon Guidance Depends on LPA-Mediated PRG-2/Radixin Signaling

Jin Cheng, Sadhna Sahani, Torben Johann Hausrat, Jenq-Wei Yang, Haichao Ji, Nikolai Schmarowski, Heiko Endle, Xinfeng Liu, Yunbo Li, Rahel Böttche, Konstantin Radyushkin, Hans M. Maric, Anna Hoerder-Suabedissen, Zoltán Molnár, Pierre-Hugues Prouvot, Thorsten Trimbuch, Olaf Ninnemann, Jisen Huai, Wei Fan, Barbara Visentin, Roger Sabbadini, Kristian Strømgaard, Albrecht Stroh, Heiko J. Luhmann, Matthias Kneussel, Robert Nitsch, Johannes Vogt

Neuron. 2016 Oct 5; 92(1): 126–142. doi: 10.1016/j.neuron.2016.08.035

PMCID:: PMC5065528

Abstract Article

Select item 481598719.

Uterine RAC1 via Pak1-ERM signaling directs normal luminal epithelial integrity conducive to on-time embryo implantation in mice

Z Tu, Q Wang, T Cui, J Wang, H Ran, H Bao, J Lu, B Wang, J P Lydon, F DeMayo, S Zhang, S Kong, X Wu, H Wang

Cell Death Differ. 2016 Jan; 23(1): 169–181. Published online 2015 Jul 17. doi: 10.1038/cdd.2015.98

PMCID:: PMC4815987

Abstract Article PDF–5.8M

Select item 448485120.

CLIC5 Stabilizes Membrane-Actin Filament Linkages at the Base of Hair Cell Stereocilia in a Molecular Complex with Radixin, Taperin, and Myosin VI

Felipe T. Salles, Leonardo R. Andrade, Soichi Tanda, M’hamed Grati, Kathleen L. Plona, Leona H. Gagnon, Kenneth R. Johnson, Bechara Kachar, Mark A. Berryman

Cytoskeleton (Hoboken) Author manuscript; available in PMC 2015 Jun 29.

Published in final edited form as: Cytoskeleton (Hoboken). 2014 Jan; 71(1): 61–78. Published online 2013 Dec 10. doi: 10.1002/cm.21159

PMCID:: PMC4484851

Abstract Article PDF–4.3M

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