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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 105979922.

Maternal thyroid hormone receptor β activation in mice sparks brown fat thermogenesis in the offspring

Rebecca Oelkrug, Lisbeth Harder, Mehdi Pedaran, Anne Hoffmann, Beke Kolms, Julica Inderhees, Sogol Gachkar, Julia Resch, Kornelia Johann, Olaf Jöhren, Kerstin Krause, Jens Mittag

Nat Commun. 2023; 14: 6742. Published online 2023 Oct 24. doi: 10.1038/s41467-023-42425-w

PMCID:: PMC10597992

Abstract Article PDF–1.8M

Select item 102536213.

Chronic Exposure to Chlorpyrifos Damages Thyroid Activity and Imbalances Hepatic Thyroid Hormones Signaling and Glucose Metabolism: Dependency of T3-FOXO1 Axis by Hyperglycemia

Teresa Peluso, Valeria Nittoli, Carla Reale, Immacolata Porreca, Filomena Russo, Luca Roberto, Antonia Giacco, Elena Silvestri, Massimo Mallardo, Mario De Felice, Concetta Ambrosino

Int J Mol Sci. 2023 Jun; 24(11): 9582. Published online 2023 May 31. doi: 10.3390/ijms24119582

PMCID:: PMC10253621

Abstract Article PDF–2.5M

Select item 96755564.

DIO3 protects against thyrotoxicosis-derived cranio-encephalic and cardiac congenital abnormalities

M. Elena Martinez, Ilka Pinz, Marilena Preda, Christine R. Norton, Thomas Gridley, Arturo Hernandez

JCI Insight. 2022 Nov 8; 7(21): e161214. Published online 2022 Nov 8. doi: 10.1172/jci.insight.161214

PMCID:: PMC9675556

Abstract Article PDF–3.9M

Select item 82373605.

Early induction of hepatic deiodinase type 1 inhibits hepatosteatosis during NAFLD progression

Eveline Bruinstroop, Jin Zhou, Madhulika Tripathi, Winifred W. Yau, Anita Boelen, Brijesh Kumar Singh, Paul M. Yen

Mol Metab. 2021 Nov; 53: 101266. Published online 2021 Jun 5. doi: 10.1016/j.molmet.2021.101266

PMCID:: PMC8237360

Abstract Article PDF–1.5M

Select item 78912006.

Human Type 1 Iodothyronine Deiodinase (DIO1) Mutations Cause Abnormal Thyroid Hormone Metabolism

Monica M. França, Alina German, Gustavo W. Fernandes, Xiao-Hui Liao, Antonio C. Bianco, Samuel Refetoff, Alexandra M. Dumitrescu

Thyroid. February 2021; 31(2): 202–207. Published online 2021 Feb 12. doi: 10.1089/thy.2020.0253

PMCID:: PMC7891200

Abstract Article PDF–377K

Select item 56596737.

An Essential Physiological Role for MCT8 in Bone in Male Mice

Victoria D. Leitch, Caterina Di Cosmo, Xiao-Hui Liao, Sam O’Boy, Thomas M. Galliford, Holly Evans, Peter I. Croucher, Alan Boyde, Alexandra Dumitrescu, Roy E. Weiss, Samuel Refetoff, Graham R. Williams, J. H. Duncan Bassett

Endocrinology. 2017 Sep 1; 158(9): 3055–3066. Published online 2017 Jun 15. doi: 10.1210/en.2017-00399

PMCID:: PMC5659673

Abstract Article

Select item 56024018.

De novo triiodothyronine formation from thyrocytes activated by thyroid-stimulating hormone

Cintia E. Citterio, Balaji Veluswamy, Sarah J. Morgan, Valerie A. Galton, J. Paul Banga, Stephen Atkins, Yoshiaki Morishita, Susanne Neumann, Rauf Latif, Marvin C. Gershengorn, Terry J. Smith, Peter Arvan

J Biol Chem. 2017 Sep 15; 292(37): 15434–15444. Published online 2017 Jul 25. doi: 10.1074/jbc.M117.784447

PMCID:: PMC5602401

Abstract Article PDF–2.0M

Select item 54173949.

The Thyroid Hormone Receptor α1 Protein Is Expressed in Embryonic Postmitotic Neurons and Persists in Most Adult Neurons

Karin Wallis, Susi Dudazy, Max van Hogerlinden, Kristina Nordström, Jens Mittag, Björn Vennström

Mol Endocrinol. October 1, 2010; 24(10): 1904–1916. doi: 10.1210/me.2010-0175

PMCID:: PMC5417394

Abstract Article

Select item 491921910.

Type 1 Deiodinase Regulates ApoA-I Gene Expression and ApoA-I Synthesis Independent of Thyroid Hormone Signaling

Jing Liu, Antonio Hernandez-Ono, Mark J. Graham, Valerie Anne Galton, Henry N. Ginsberg

Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2017 Jul 1.

Published in final edited form as: Arterioscler Thromb Vasc Biol. 2016 Jul; 36(7): 1356–1366. Published online 2016 May 5. doi: 10.1161/ATVBAHA.116.307330

PMCID:: PMC4919219

Abstract Article PDF–950K

Select item 465317511.

Perinatal deiodinase 2 expression in hepatocytes defines epigenetic susceptibility to liver steatosis and obesity

Tatiana L. Fonseca, Gustavo W. Fernandes, Elizabeth A. McAninch, Barbara M. L. C. Bocco, Sherine M. Abdalla, Miriam O. Ribeiro, Petra Mohácsik, Csaba Fekete, Daofeng Li, Xiaoyun Xing, Ting Wang, Balázs Gereben, Antonio C. Bianco

Proc Natl Acad Sci U S A. 2015 Nov 10; 112(45): 14018–14023. Published online 2015 Oct 27. doi: 10.1073/pnas.1508943112

PMCID:: PMC4653175

Abstract Article PDF–1.0M

Select item 436141012.

Adult Mice Lacking the Type 2 Iodothyronine Deiodinase Have Increased Subchondral Bone but Normal Articular Cartilage

Julian A. Waung, J.H. Duncan Bassett, Graham R. Williams

Thyroid. 2015 Mar 1; 25(3): 269–277. doi: 10.1089/thy.2014.0476

PMCID:: PMC4361410

Abstract Article PDF–1015K

Select item 428250813.

The miR-379/miR-410 cluster at the imprinted Dlk1-Dio3 domain controls neonatal metabolic adaptation

Stéphane Labialle, Virginie Marty, Marie-Line Bortolin-Cavaillé, Magali Hoareau-Osman, Jean-Philippe Pradère, Philippe Valet, Pascal GP Martin, Jérôme Cavaillé

EMBO J. 2014 Oct 1; 33(19): 2216–2230. Published online 2014 Aug 14. doi: 10.15252/embj.201387038

PMCID:: PMC4282508

Abstract Article PDF–1.8M

Select item 416492414.

Life Without the Iodothyronine Deiodinases

Valerie Anne Galton, Ellis de Waard, Albert F. Parlow, Donald L. St Germain, Arturo Hernandez

Endocrinology. 2014 Oct; 155(10): 4081–4087. Published online 2014 Jun 20. doi: 10.1210/en.2014-1184

PMCID:: PMC4164924

Abstract Article

Select item 409799715.

The 5′-Deiodinases Are Not Essential for the Fasting-Induced Decrease in Circulating Thyroid Hormone Levels in Male Mice: Possible Roles for the Type 3 Deiodinase and Tissue Sequestration of Hormone

Valerie Anne Galton, Arturo Hernandez, Donald L. St. Germain

Endocrinology. 2014 Aug; 155(8): 3172–3181. Published online 2014 Mar 17. doi: 10.1210/en.2013-1884

PMCID:: PMC4097997

Abstract Article

Select item 383607316.

Mct8-Deficient Mice Have Increased Energy Expenditure and Reduced Fat Mass That Is Abrogated by Normalization of Serum T₃ Levels

Caterina Di Cosmo, Xiao-Hui Liao, Honggang Ye, Alfonso Massimiliano Ferrara, Roy E. Weiss, Samuel Refetoff, Alexandra M. Dumitrescu

Endocrinology. 2013 Dec; 154(12): 4885–4895. Published online 2013 Sep 12. doi: 10.1210/en.2013-1150

PMCID:: PMC3836073

Abstract Article

Select item 368927917.

Changes in Thyroid Status During Perinatal Development of MCT8-Deficient Male Mice

Alfonso Massimiliano Ferrara, Xiao-Hui Liao, Pilar Gil-Ibáñez, Teresa Marcinkowski, Juan Bernal, Roy E. Weiss, Alexandra M. Dumitrescu, Samuel Refetoff

Endocrinology. 2013 Jul; 154(7): 2533–2541. Published online 2013 May 21. doi: 10.1210/en.2012-2031

PMCID:: PMC3689279

Abstract Article

Select item 357241018.

A conditional knockout resource for the genome–wide study of mouse gene function

William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley

Nature. Author manuscript; available in PMC 2013 Feb 14.

Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163

PMCID:: PMC3572410

Abstract Article PDF–1.1M

Select item 331494919.

Imprinted Gene Dosage Is Critical for the Transition to Independent Life

Marika Charalambous, Sacramento R. Ferron, Simao T. da Rocha, Andrew J. Murray, Timothy Rowland, Mitsuteru Ito, Karin Schuster-Gossler, Arturo Hernandez, Anne C. Ferguson-Smith

Cell Metab. 2012 Feb 8; 15(2): 209–221. doi: 10.1016/j.cmet.2012.01.006

PMCID:: PMC3314949

Abstract Article PDF–1.3M

Select item 328699420.

Defective transcription initiation causes postnatal growth failure in a mouse model of nucleotide excision repair (NER) progeria

Irene Kamileri, Ismene Karakasilioti, Aria Sideri, Theodoros Kosteas, Antonis Tatarakis, Iannis Talianidis, George A. Garinis

Proc Natl Acad Sci U S A. 2012 Feb 21; 109(8): 2995–3000. Published online 2012 Feb 8. doi: 10.1073/pnas.1114941109

PMCID:: PMC3286994

Abstract Article PDF–725K

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