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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 107693502.

Identification of new ciliary signaling pathways in the brain and insights into neurological disorders

Abdelhalim Loukil, Emma Ebright, Akiyoshi Uezu, Yudong Gao, Scott H Soderling, Sarah C. Goetz

Version 1. bioRxiv. Preprint. 2023 Dec 21. doi: 10.1101/2023.12.20.572700

PMCID:: PMC10769350

Abstract Article PDF–11M

Select item 105448283.

Clustering of phosphatase RPTPα promotes Src signaling and the arthritogenic action of synovial fibroblasts

Sho Sendo, William B. Kiosses, Shen Yang, Dennis J. Wu, Daniel W. K. Lee, Lin Liu, Yael Aschner, Allison J. Vela, Gregory P. Downey, Eugenio Santelli, Nunzio Bottini

Sci Signal. Author manuscript; available in PMC 2024 Jul 4.

Published in final edited form as: Sci Signal. 2023 Jul 4; 16(792): eabn8668. Published online 2023 Jul 4. doi: 10.1126/scisignal.abn8668

PMCID:: PMC10544828

Abstract Article PDF–3.8M

Select item 103078524.

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility

Juan Gu, Pingyang Ke, Haokun Guo, Jing Liu, Yan Liu, Xin Tian, Zhuo Huang, Xin Xu, Demei Xu, Yuanlin Ma, Xuefeng Wang, Fei Xiao

Cell Death Differ. 2023 Jul; 30(7): 1726–1741. Published online 2023 May 4. doi: 10.1038/s41418-023-01174-5

PMCID:: PMC10307852

Abstract Article PDF–8.8M

Select item 102409985.

PTP4A2 promotes lysophagy by dephosphorylation of VCP/p97 at Tyr805

Yunpeng Bai, Guimei Yu, Hong-Ming Zhou, Ovini Amarasinghe, Yuan Zhou, Peipei Zhu, Qinglin Li, Lujuan Zhang, Frederick Nguele Meke, Yiming Miao, Eli Chapman, W. Andy Tao, Zhong-Yin Zhang

Autophagy. 2023; 19(5): 1562–1581. Published online 2022 Nov 7. doi: 10.1080/15548627.2022.2140558

PMCID:: PMC10240998

Abstract Article PDF–4.4M

Select item 92557116.

PTPα promotes fibroproliferative responses after acute lung injury

Yael Aschner, Kelly A. Correll, Keriann M. Beke, Daniel G. Foster, Helen M. Roybal, Meghan R. Nelson, Carly L. Meador, Matthew Strand, Kelsey C. Anderson, Camille M. Moore, Paul R. Reynolds, Katrina W. Kopf, Ellen L. Burnham, Gregory P. Downey

Am J Physiol Lung Cell Mol Physiol. 2022 Jul 1; 323(1): L69–L83. Published online 2022 Jun 7. doi: 10.1152/ajplung.00436.2021

PMCID:: PMC9255711

Abstract Article

Select item 82709567.

Transcriptional profiling of mESC-derived tendon and fibrocartilage cell fate switch

Deepak A. Kaji, Angela M. Montero, Roosheel Patel, Alice H. Huang

Nat Commun. 2021; 12: 4208. Published online 2021 Jul 9. doi: 10.1038/s41467-021-24535-5

PMCID:: PMC8270956

Abstract Article PDF–4.7M

Select item 79387708.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 74739339.

Protein tyrosine phosphatase-α amplifies transforming growth factor-β-dependent profibrotic signaling in lung fibroblasts

Yael Aschner, Meghan Nelson, Matthew Brenner, Helen Roybal, Keriann Beke, Carly Meador, Daniel Foster, Kelly A. Correll, Paul R. Reynolds, Kelsey Anderson, Elizabeth F. Redente, Jennifer Matsuda, David W. H. Riches, Steve D. Groshong, Ambra Pozzi, Jan Sap, Qin Wang, Dhaarmini Rajshankar, Christopher A. G. McCulloch, Rachel L. Zemans, Gregory P. Downey

Am J Physiol Lung Cell Mol Physiol. 2020 Aug 1; 319(2): L294–L311. Published online 2020 Jun 3. doi: 10.1152/ajplung.00235.2019

PMCID:: PMC7473933

Abstract Article

Select item 564139110.

Mitotic Activation of Protein-tyrosine Phosphatase α and Regulation of Its Src-mediated Transforming Activity by Its Sites of Protein Kinase C Phosphorylation

Xin-Min Zheng, Ross J. Resnick, David Shalloway

J Biol Chem. Author manuscript; available in PMC 2017 Oct 15.

Published in final edited form as: J Biol Chem. 2002 Jun 14; 277(24): 21922–21929. Published online 2002 Mar 28. doi: 10.1074/jbc.M201394200

PMCID:: PMC5641391

Abstract Article PDF–3.9M

Select item 487686411.

Extracellular domain dependence of PTPα transforming activity

Barbara Tremper-Wells, Ross J. Resnick, Xinmin Zheng, Leslie J. Holsinger, David Shalloway

Genes Cells. Author manuscript; available in PMC 2016 May 23.

Published in final edited form as: Genes Cells. 2010 Jun; 15(7): 711–724. Published online 2010 Jun 7. doi: 10.1111/j.1365-2443.2010.01410.x

PMCID:: PMC4876864

Abstract Article PDF–856K

Select item 477025912.

“Receptor protein tyrosine phosphatase alpha enhances rheumatoid synovial fibroblast signaling and promotes arthritis in mice”

Stephanie M. Stanford, Mattias N. D. Svensson, Cristiano Sacchetti, Caila A. Pilo, Dennis J. Wu, William B. Kiosses, Annelie Hellvard, Brith Bergum, German R. Aleman Muench, Christian Elly, Yun-Cai Liu, Jeroen den Hertog, Ari Elson, Jan Sap, Piotr Mydel, David L. Boyle, Maripat Corr, Gary S. Firestein, Nunzio Bottini

Arthritis Rheumatol. Author manuscript; available in PMC 2017 Feb 1.

Published in final edited form as: Arthritis Rheumatol. 2016 Feb; 68(2): 359–369. doi: 10.1002/art.39442

PMCID:: PMC4770259

Abstract Article PDF–1.7M

Select item 451662813.

STriatal-Enriched protein tyrosine Phosphatase (STEP) Regulates the PTPα/Fyn Signaling Pathway

Jian Xu, Pradeep Kurup, Ethan Foscue, Paul J. Lombroso

J Neurochem. Author manuscript; available in PMC 2016 Aug 1.

Published in final edited form as: J Neurochem. 2015 Aug; 134(4): 629–641. Published online 2015 May 25. doi: 10.1111/jnc.13160

PMCID:: PMC4516628

Abstract Article PDF–1.2M

Select item 438043814.

Expression of the Immunoglobulin Superfamily Cell Adhesion Molecules in the Developing Spinal Cord and Dorsal Root Ganglion

Zirong Gu, Fumiyasu Imai, In Jung Kim, Hiroko Fujita, Kei ichi Katayama, Kensaku Mori, Yoshihiro Yoshihara, Yutaka Yoshida

PLoS One. 2015; 10(3): e0121550. Published online 2015 Mar 31. doi: 10.1371/journal.pone.0121550

PMCID:: PMC4380438

Abstract Article PDF–36M

Select item 414028215.

Interactions of the Protein-tyrosine Phosphatase-α with the Focal Adhesion Targeting Domain of Focal Adhesion Kinase Are Involved in Interleukin-1 Signaling in Fibroblasts

Qin Wang, Yongqiang Wang, Dominik Fritz, Dhaarmini Rajshankar, Gregory P. Downey, Christopher A. McCulloch

J Biol Chem. 2014 Jun 27; 289(26): 18427–18441. Published online 2014 May 12. doi: 10.1074/jbc.M113.540294

PMCID:: PMC4140282

Abstract Article PDF–5.6M

Select item 403850616.

Protein tyrosine phosphatases ε and α perform nonredundant roles in osteoclasts

Eynat Finkelshtein, Sutada Lotinun, Einat Levy-Apter, Esther Arman, Jeroen den Hertog, Roland Baron, Ari Elson

Mol Biol Cell. 2014 Jun 1; 25(11): 1808–1818. doi: 10.1091/mbc.E14-03-0788

PMCID:: PMC4038506

Abstract Article PDF–1.9M

Select item 400598317.

Protein Tyrosine Phosphatase α Mediates Profibrotic Signaling in Lung Fibroblasts through TGF-β Responsiveness

Yael Aschner, Anthony P. Khalifah, Natalie Briones, Cory Yamashita, Lior Dolgonos, Scott K. Young, Megan N. Campbell, David W.H. Riches, Elizabeth F. Redente, William J. Janssen, Peter M. Henson, Jan Sap, Nathalie Vacaresse, Andras Kapus, Christopher A.G. McCulloch, Rachel L. Zemans, Gregory P. Downey

Am J Pathol. 2014 May; 184(5): 1489–1502. doi: 10.1016/j.ajpath.2014.01.016