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Select item 105916721.

Distinct mechanisms for sebaceous gland self-renewal and regeneration provide durability in response to injury

Natalia A. Veniaminova, Yunlong Y. Jia, Adrien M. Hartigan, Thomas J. Huyge, Shih-Ying Tsai, Marina Grachtchouk, Seitaro Nakagawa, Andrzej A. Dlugosz, Scott X. Atwood, Sunny Y. Wong

Cell Rep. Author manuscript; available in PMC 2023 Oct 23.

Published in final edited form as: Cell Rep. 2023 Sep 26; 42(9): 113121. Published online 2023 Sep 19. doi: 10.1016/j.celrep.2023.113121

PMCID:: PMC10591672

Abstract Article PDF–3.4M

Select item 98189942.

Stage-Specific L-Proline Uptake by Amino Acid Transporter Slc6a19/B⁰AT1 Is Required for Optimal Preimplantation Embryo Development in Mice

Tamara Treleaven, Matthew Zada, Rajini Nagarajah, Charles G. Bailey, John E. J. Rasko, Michael B. Morris, Margot L. Day

Cells. 2023 Jan; 12(1): 18. Published online 2022 Dec 21. doi: 10.3390/cells12010018

PMCID:: PMC9818994

Abstract Article PDF–1.9M

Select item 97025393.

Maternal heterozygosity of Slc6a19 causes metabolic perturbation and congenital NAD deficiency disorder in mice

Hartmut Cuny, Kayleigh Bozon, Rosemary B. Kirk, Delicia Z. Sheng, Stefan Bröer, Sally L. Dunwoodie

Dis Model Mech. 2023 May 1; 16(5): dmm049647. Published online 2022 Nov 14. doi: 10.1242/dmm.049647

PMCID:: PMC9702539

Abstract Article

Select item 88944894.

Changes to gut amino acid transporters and microbiome associated with increased E/I ratio in Chd8^+/− mouse model of ASD-like behavior

You Yu, Bing Zhang, Peifeng Ji, Zhenqiang Zuo, Yongxi Huang, Ning Wang, Chang Liu, Shuang-Jiang Liu, Fangqing Zhao

Nat Commun. 2022; 13: 1151. Published online 2022 Mar 3. doi: 10.1038/s41467-022-28746-2

PMCID:: PMC8894489

Abstract Article PDF–3.1M

Select item 72833395.

Restriction of essential amino acids dictates the systemic metabolic response to dietary protein dilution

Yann W. Yap, Patricia M. Rusu, Andrea Y. Chan, Barbara C. Fam, Andreas Jungmann, Samantha M. Solon-Biet, Christopher K. Barlow, Darren J. Creek, Cheng Huang, Ralf B. Schittenhelm, Bruce Morgan, Dieter Schmoll, Bente Kiens, Matthew D. W. Piper, Mathias Heikenwälder, Stephen J. Simpson, Stefan Bröer, Sofianos Andrikopoulos, Oliver J. Müller, Adam J. Rose

Nat Commun. 2020; 11: 2894. Published online 2020 Jun 9. doi: 10.1038/s41467-020-16568-z

PMCID:: PMC7283339

Abstract Article PDF–2.2M

Select item 70942826.

Tissue-Specific Amino Acid Transporter Partners ACE2 and Collectrin Differentially Interact With Hartnup Mutations

Simone M.R. Camargo, Dustin Singer, Victoria Makrides, Katja Huggel, Klaas M. Pos, Carsten A. Wagner, Keiji Kuba, Ursula Danilczyk, Flemming Skovby, Robert Kleta, Josef M. Penninger, François Verrey

Gastroenterology. 2009 Mar; 136(3): 872–882.e3. Published online 2008 Oct 29. doi: 10.1053/j.gastro.2008.10.055

PMCID:: PMC7094282

Abstract Article PDF–1.3M

Select item 67709487.

Mice Lacking the Intestinal and Renal Neutral Amino Acid Transporter SLC6A19 Demonstrate the Relationship between Dietary Protein Intake and Amino Acid Malabsorption

Kiran Javed, Stefan Bröer

Nutrients. 2019 Sep; 11(9): 2024. Published online 2019 Aug 29. doi: 10.3390/nu11092024

PMCID:: PMC6770948

Abstract Article PDF–3.3M

Select item 61244518.

Inhibiting neutral amino acid transport for the treatment of phenylketonuria

Adam M. Belanger, Malgorzata Przybylska, Estelle Gefteas, Matthew Furgerson, Sarah Geller, Alla Kloss, Seng H. Cheng, Yunxiang Zhu, Nelson S. Yew

JCI Insight. 2018 Jul 26; 3(14): e121762. Published online 2018 Jul 26. doi: 10.1172/jci.insight.121762

PMCID:: PMC6124451

Abstract Article PDF–4.6M

Select item 45918169.

Molecular Basis for the Interaction of the Mammalian Amino Acid Transporters B⁰AT1 and B⁰AT3 with Their Ancillary Protein Collectrin

Stephen J. Fairweather, Angelika Bröer, Nandhitha Subramanian, Emrah Tumer, Qi Cheng, Dieter Schmoll, Megan L. O'Mara, Stefan Bröer

J Biol Chem. 2015 Oct 2; 290(40): 24308–24325. Published online 2015 Aug 3. doi: 10.1074/jbc.M115.648519

PMCID:: PMC4591816

Abstract Article PDF–2.1M

Select item 448439210.

Exome sequencing reveals pathogenic mutations in 91 strains of mice with Mendelian disorders

Heather Fairfield, Anuj Srivastava, Guruprasad Ananda, Rangjiao Liu, Martin Kircher, Anuradha Lakshminarayana, Belinda S. Harris, Son Yong Karst, Louise A. Dionne, Coleen C. Kane, Michelle Curtain, Melissa L. Berry, Patricia F. Ward-Bailey, Ian Greenstein, Candice Byers, Anne Czechanski, Jocelyn Sharp, Kristina Palmer, Polyxeni Gudis, Whitney Martin, Abby Tadenev, Laurent Bogdanik, C. Herbert Pratt, Bo Chang, David G. Schroeder, Gregory A. Cox, Paul Cliften, Jeffrey Milbrandt, Stephen Murray, Robert Burgess, David E. Bergstrom, Leah Rae Donahue, Hanan Hamamy, Amira Masri, Federico A. Santoni, Periklis Makrythanasis, Stylianos E. Antonarakis, Jay Shendure, Laura G. Reinholdt

Genome Res. 2015 Jul; 25(7): 948–957. doi: 10.1101/gr.186882.114

PMCID:: PMC4484392

Abstract Article PDF–604K

Select item 442101911.

Mice lacking neutral amino acid transporter B⁰AT1 (Slc6a19) have elevated levels of FGF21 and GLP-1 and improved glycaemic control

Yang Jiang, Adam J. Rose, Tjeerd P. Sijmonsma, Angelika Bröer, Anja Pfenninger, Stephan Herzig, Dieter Schmoll, Stefan Bröer

Mol Metab. 2015 May; 4(5): 406–417. Published online 2015 Feb 16. doi: 10.1016/j.molmet.2015.02.003

PMCID:: PMC4421019

Abstract Article PDF–1.4M

Select item 383712412.

Enterocyte-specific Regulation of the Apical Nutrient Transporter SLC6A19 (B⁰AT1) by Transcriptional and Epigenetic Networks

Emrah Tümer, Angelika Bröer, Sarojini Balkrishna, Torsten Jülich, Stefan Bröer

J Biol Chem. 2013 Nov 22; 288(47): 33813–33823. Published online 2013 Oct 11. doi: 10.1074/jbc.M113.482760

PMCID:: PMC3837124

Abstract Article PDF–2.3M

Select item 357241013.

A conditional knockout resource for the genome–wide study of mouse gene function

William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley

Nature. Author manuscript; available in PMC 2013 Feb 14.

Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163

PMCID:: PMC3572410

Abstract Article PDF–1.1M

Select item 340804514.

Intestinal peptidases form functional complexes with the neutral amino acid transporter B⁰AT1

Stephen J. Fairweather, Angelika Bröer, Megan L. O'Mara, Stefan Bröer

Biochem J. 2012 Aug 15; 446(Pt 1): 135–148. Prepublished online 2012 Jun 7. Published online 2012 Jul 27. doi: 10.1042/BJ20120307

PMCID:: PMC3408045

Abstract Article PDF–1.9M

Select item 317805915.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 314362816.

Impaired Nutrient Signaling and Body Weight Control in a Na⁺ Neutral Amino Acid Cotransporter (Slc6a19)-deficient Mouse

Angelika Bröer, Torsten Juelich, Jessica M. Vanslambrouck, Nadine Tietze, Peter S. Solomon, Jeff Holst, Charles G. Bailey, John E. J. Rasko, Stefan Bröer

J Biol Chem. 2011 Jul 29; 286(30): 26638–26651. Published online 2011 Jun 2. doi: 10.1074/jbc.M111.241323

PMCID:: PMC3143628

Abstract Article PDF–2.9M

Select item 302253417.

A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo

Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio

PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582

PMCID:: PMC3022534

Abstract Article PDF–3.8M

Select item 263408518.

The European Renal Genome Project: An Integrated Approach Towards Understanding the Genetics of Kidney Development and Disease

TE Willnow, C Antignac, AW Brändli, EI Christensen, RD Cox, D Davidson, JA Davies, O Devuyst, G Eichele, ND Hastie, PJ Verroust, A Schedl, IC Meij

Organogenesis. 2005 Apr-Jun; 2(2): 42–47. doi: 10.4161/org.2.2.2118

PMCID:: PMC2634085

Abstract Article PDF–629K

Select item 141356819.

BGEM: An In Situ Hybridization Database of Gene Expression in the Embryonic and Adult Mouse Nervous System

Susan Magdaleno, Patricia Jensen, Craig L Brumwell, Anna Seal, Karen Lehman, Andrew Asbury, Tony Cheung, Tommie Cornelius, Diana M Batten, Christopher Eden, Shannon M Norland, Dennis S Rice, Nilesh Dosooye, Sundeep Shakya, Perdeep Mehta, Tom Curran

PLoS Biol. 2006 Apr; 4(4): e86. Published online 2006 Mar 28. doi: 10.1371/journal.pbio.0040086

PMCID:: PMC1413568

Article PDF–99K

Select item 118072520.

Characterization of mouse amino acid transporter B⁰AT1 (slc6a19)

Christoph Böhmer, Angelika Bröer, Michael Munzinger, Sonja Kowalczuk, John E. J. Rasko, Florian Lang, Stefan Bröer

Biochem J. 2005 Aug 1; 389(Pt 3): 745–751. Prepublished online 2005 Apr 1. Published online 2005 Jul 26. doi: 10.1042/BJ20050083

PMCID:: PMC1180725

Abstract Article PDF–456K

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