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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 98813012.

Deletion of Tbc1d4/As160 abrogates cardiac glucose uptake and increases myocardial damage after ischemia/reperfusion

C. Binsch, D. M. Barbosa, G. Hansen-Dille, M. Hubert, S. M. Hodge, M. Kolasa, K. Jeruschke, J. Weiß, C. Springer, S. Gorressen, J. W. Fischer, M. Lienhard, R. Herwig, S. Börno, B. Timmermann, A. L. Cremer, H. Backes, A. Chadt, H. Al-Hasani

Cardiovasc Diabetol. 2023; 22: 17. Published online 2023 Jan 27. doi: 10.1186/s12933-023-01746-2

PMCID:: PMC9881301

Abstract Article PDF–3.0M

Select item 90747443.

Illumination of the Endogenous Insulin-Regulated TBC1D4 Interactome in Human Skeletal Muscle

Jeppe K. Larsen, Magnus R. Larsen, Jesper B. Birk, Dorte E. Steenberg, Janne R. Hingst, Kurt Højlund, Alexandra Chadt, Hadi Al-Hasani, Atul S. Deshmukh, Jørgen F.P. Wojtaszewski, Rasmus Kjøbsted

Diabetes. 2022 May; 71(5): 906–920. Published online 2022 Feb 22. doi: 10.2337/db21-0855

PMCID:: PMC9074744

Abstract Article PDF–3.0M

Select item 83132394.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 79387705.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 61938726.

Rearrangement of the Protein Phosphatase 1 Interactome during Heart Failure Progression

David Y. Chiang, Katherina M. Alsina, Eleonora Corradini, Martin Fitzpatrick, Li Ni, Satadru K. Lahiri, Julia Reynolds, Xiaolu Pan, Larry Scott, Jr, Albert J.R. Heck, Xander H.T. Wehrens

Circulation. Author manuscript; available in PMC 2019 Oct 9.

Published in final edited form as: Circulation. 2018 Oct 9; 138(15): 1569–1581. doi: 10.1161/CIRCULATIONAHA.118.034361

PMCID:: PMC6193872

Abstract Article PDF–2.4M

Select item 60362007.

Usp25m protease regulates ubiquitin-like processing of TUG proteins to control GLUT4 glucose transporter translocation in adipocytes

Estifanos N. Habtemichael, Don T. Li, Abel Alcázar-Román, Xavier O. Westergaard, Muyi Li, Max C. Petersen, Hanbing Li, Stephen G. DeVries, Eric Li, Omar Julca-Zevallos, Joseph S. Wolenski, Jonathan S. Bogan

J Biol Chem. 2018 Jul 6; 293(27): 10466–10486. Published online 2018 May 17. doi: 10.1074/jbc.RA118.003021

PMCID:: PMC6036200

Abstract Article PDF–4.2M

Select item 57009788.

Stress-responsive FKBP51 regulates AKT2-AS160 signaling and metabolic function

Georgia Balsevich, Alexander S. Häusl, Carola W. Meyer, Stoyo Karamihalev, Xixi Feng, Max L. Pöhlmann, Carine Dournes, Andres Uribe-Marino, Sara Santarelli, Christiana Labermaier, Kathrin Hafner, Tianqi Mao, Michaela Breitsamer, Marily Theodoropoulou, Christian Namendorf, Manfred Uhr, Marcelo Paez-Pereda, Gerhard Winter, Felix Hausch, Alon Chen, Matthias H. Tschöp, Theo Rein, Nils C. Gassen, Mathias V. Schmidt

Nat Commun. 2017; 8: 1725. Published online 2017 Nov 23. doi: 10.1038/s41467-017-01783-y

PMCID:: PMC5700978

Abstract Article PDF–1.3M

Select item 54194019.

Regulation of Glucose Transporter 4 Translocation by the Rab Guanosine Triphosphatase-Activating Protein AS160/TBC1D4: Role of Phosphorylation and Membrane Association

Jacqueline Stöckli, Jonathan R. Davey, Cordula Hohnen-Behrens, Aimin Xu, David E. James, Georg Ramm

Mol Endocrinol. December 1, 2008; 22(12): 2703–2715. doi: 10.1210/me.2008-0111

PMCID:: PMC5419401

Abstract Article

Select item 529582110.

High-throughput discovery of novel developmental phenotypes

Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray

Nature. Author manuscript; available in PMC 2017 Mar 14.

Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356

Correction in:: Nature. 2017 Nov 16; 551(7680): 398.

PMCID:: PMC5295821

Abstract Article PDF–3.0M

Select item 501135811.

Six1 homeoprotein drives myofiber type IIA specialization in soleus muscle

Iori Sakakibara, Maud Wurmser, Matthieu Dos Santos, Marc Santolini, Serge Ducommun, Romain Davaze, Anthony Guernec, Kei Sakamoto, Pascal Maire

Skelet Muscle. 2016; 6(1): 30. Published online 2016 Sep 5. doi: 10.1186/s13395-016-0102-x

PMCID:: PMC5011358

Abstract Article PDF–3.5M

Select item 495756812.

AS160 controls eukaryotic cell cycle and proliferation by regulating the CDK inhibitor p21

Pianchou Gongpan, Yanting Lu, Fang Wang, Yuhui Xu, Wenyong Xiong

Cell Cycle. 2016; 15(13): 1733–1741. Published online 2016 May 6. doi: 10.1080/15384101.2016.1183853

PMCID:: PMC4957568

Abstract Article PDF–1.0M

Select item 488852813.

Rab GAPs AS160 and Tbc1d1 play nonredundant roles in the regulation of glucose and energy homeostasis in mice

Stefan R. Hargett, Natalie N. Walker, Susanna R. Keller

Am J Physiol Endocrinol Metab. 2016 Feb 15; 310(4): E276–E288. Published online 2015 Dec 1. doi: 10.1152/ajpendo.00342.2015

PMCID:: PMC4888528

Abstract Article

Select item 462565914.

Akt Substrate of 160 kD Regulates Na⁺,K⁺-ATPase Trafficking in Response to Energy Depletion and Renal Ischemia

Daiane S. Alves, Gunilla Thulin, Johannes Loffing, Michael Kashgarian, Michael J. Caplan

J Am Soc Nephrol. 2015 Nov; 26(11): 2765–2776. Published online 2015 Mar 18. doi: 10.1681/ASN.2013101040

PMCID:: PMC4625659

Abstract Article

Select item 441448415.

PKB-Mediated Thr⁶⁴⁹ Phosphorylation of AS160/TBC1D4 Regulates the R-Wave Amplitude in the Heart

Chao Quan, Bingxian Xie, Hong Yu Wang, Shuai Chen

PLoS One. 2015; 10(4): e0124491. Published online 2015 Apr 29. doi: 10.1371/journal.pone.0124491

PMCID:: PMC4414484

Abstract Article PDF–1.4M

Select item 396495516.

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data

Gautier Koscielny, Gagarine Yaikhom, Vivek Iyer, Terrence F. Meehan, Hugh Morgan, Julian Atienza-Herrero, Andrew Blake, Chao-Kung Chen, Richard Easty, Armida Di Fenza, Tanja Fiegel, Mark Grifiths, Alan Horne, Natasha A. Karp, Natalja Kurbatova, Jeremy C. Mason, Peter Matthews, Darren J. Oakley, Asfand Qazi, Jack Regnart, Ahmad Retha, Luis A. Santos, Duncan J. Sneddon, Jonathan Warren, Henrik Westerberg, Robert J. Wilson, David G. Melvin, Damian Smedley, Steve D. M. Brown, Paul Flicek, William C. Skarnes, Ann-Marie Mallon, Helen Parkinson

Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D802–D809. Published online 2013 Nov 3. doi: 10.1093/nar/gkt977