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Select item 113434241.

shRNA-mediated down-regulation of Acsl1 reverses skeletal muscle insulin resistance in obese C57BL6/J mice

Kamila Roszczyc-Owsiejczuk, Monika Imierska, Emilia Sokołowska, Mariusz Kuźmicki, Karolina Pogodzińska, Agnieszka Błachnio-Zabielska, Piotr Zabielski

PLoS One. 2024; 19(8): e0307802. Published online 2024 Aug 23. doi: 10.1371/journal.pone.0307802

PMCID:: PMC11343424

Abstract Article PDF–2.1M

Select item 111582892.

Acyl‐CoA synthetase as a cancer survival factor: its inhibition enhances the efficacy of etoposide

Tetsuo Mashima, Shigeo Sato, Sachiko Okabe, Satoshi Miyata, Masaaki Matsuura, Yoshikazu Sugimoto, Takashi Tsuruo, Hiroyuki Seimiya

Cancer Sci. 2009 Aug; 100(8): 1556–1562. Published online 2009 May 13. doi: 10.1111/j.1349-7006.2009.01203.x

PMCID:: PMC11158289

Abstract Article PDF–1.6M

Select item 109535653.

Cfp1 Controls Cardiomyocyte Maturation by Modifying Histone H3K4me3 of Structural, Metabolic, and Contractile Related Genes

Changzhu Li, Yang Zhang, Jingling Shen, Hairong Bao, Yue Zhao, Desheng Li, Sijia Li, Yining Liu, Jiming Yang, Zhiwen Zhou, Kangyi Gao, Lexin Zhao, Yao Pei, Yanjie Lu, Zhenwei Pan, Benzhi Cai

Adv Sci (Weinh) 2024 Mar; 11(11): 2305992. Published online 2024 Jan 9. doi: 10.1002/advs.202305992

PMCID:: PMC10953565

Abstract Article PDF–5.8M

Select item 107707164.

Fatty acids and inflammatory stimuli induce expression of long-chain acyl-CoA synthetase 1 to promote lipid remodeling in diabetic kidney disease

Chih-Hong Wang, Surbhi, Sayhaan Goraya, Jaeman Byun, Subramaniam Pennathur

J Biol Chem. 2024 Jan; 300(1): 105502. Published online 2023 Nov 26. doi: 10.1016/j.jbc.2023.105502

PMCID:: PMC10770716

Abstract Article PDF–2.6M

Select item 107213115.

Heterogeneous cardiac sympathetic innervation gradients promote arrhythmogenesis in murine dilated cardiomyopathy

Al-Hassan J. Dajani, Michael B. Liu, Michael A. Olaopa, Lucian Cao, Carla Valenzuela-Ripoll, Timothy J. Davis, Megan D. Poston, Elizabeth H. Smith, Jaime Contreras, Marissa Pennino, Christopher M. Waldmann, Donald B. Hoover, Jason T. Lee, Patrick Y. Jay, Ali Javaheri, Roger Slavik, Zhilin Qu, Olujimi A. Ajijola

JCI Insight. 2023 Nov 22; 8(22): e157956. Published online 2023 Nov 22. doi: 10.1172/jci.insight.157956

PMCID:: PMC10721311

Abstract Article PDF–11M

Select item 102453886.

Loss of long-chain acyl-CoA synthetase 1 promotes hepatocyte death in alcohol-induced steatohepatitis

Haibo Dong, Wei Zhong, Wenliang Zhang, Liuyi Hao, Wei Guo, Ruichao Yue, Xinguo Sun, Zhaoli Sun, Ramon Bataller, Zhanxiang Zhou

Metabolism. Author manuscript; available in PMC 2023 Jun 7.

Published in final edited form as: Metabolism. 2023 Jan; 138: 155334. Published online 2022 Oct 28. doi: 10.1016/j.metabol.2022.155334

PMCID:: PMC10245388

Abstract Article PDF–3.0M

Select item 94392257.

Transcriptional regulation of Acsl1 by CHREBP and NF-kappa B in macrophages during hyperglycemia and inflammation

Prashanth Thevkar-Nagesh, Justine Habault, Maud Voisin, Sophie E. Ruff, Susan Ha, Rachel Ruoff, Xi Chen, Shruti Rawal, Tarik Zahr, Gyongyi Szabo, Inez Rogatsky, Edward A. Fisher, Michael J. Garabedian

PLoS One. 2022; 17(9): e0272986. Published online 2022 Sep 2. doi: 10.1371/journal.pone.0272986

PMCID:: PMC9439225

Abstract Article PDF–1.7M

Select item 87083378.

Inhibiting ACSL1-Related Ferroptosis Restrains Murine Coronavirus Infection

Huawei Xia, Zeming Zhang, Fuping You

Viruses. 2021 Dec; 13(12): 2383. Published online 2021 Nov 28. doi: 10.3390/v13122383

PMCID:: PMC8708337

Abstract Article PDF–2.9M

Select item 85263419.

Hepatic proteome analysis reveals altered mitochondrial metabolism and suppressed acyl-CoA synthetase-1 in colon-26 tumor-induced cachexia

Andy V. Khamoui, Dorota Tokmina-Roszyk, Harry B. Rossiter, Gregg B. Fields, Nishant P. Visavadiya

Physiol Genomics. 2020 May 1; 52(5): 203–216. Published online 2020 Mar 9. doi: 10.1152/physiolgenomics.00124.2019

PMCID:: PMC8526341

Abstract Article

Select item 849020110.

An Essential Role of the N-Terminal Region of ACSL1 in Linking Free Fatty Acids to Mitochondrial β-Oxidation in C2C12 Myotubes

Jinyan Nan, Ji Seon Lee, Seung-Ah Lee, Dong-Sup Lee, Kyong Soo Park, Sung Soo Chung

Mol Cells. 2021 Sep 30; 44(9): 637–646. Published online 2021 Sep 13. doi: 10.14348/molcells.2021.0077

PMCID:: PMC8490201

Abstract Article PDF–2.6M

Select item 793877011.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 771060712.

Tank-binding kinase 1 regulates the localization of acyl-CoA synthetase ACSL1 to control hepatic fatty acid oxidation

Jin Young Huh, Shannon M. Reilly, Mohammad Abu-Odeh, Anne N. Murphy, Sushil K. Mahata, Jinyu Zhang, Yoori Cho, Jong Bae Seo, Chao-Wei Hung, Courtney R. Green, Christian M. Metallo, Alan R. Saltiel

Cell Metab. Author manuscript; available in PMC 2021 Dec 1.

Published in final edited form as: Cell Metab. 2020 Dec 1; 32(6): 1012–1027.e7. Published online 2020 Nov 4. doi: 10.1016/j.cmet.2020.10.010

PMCID:: PMC7710607

Abstract Article PDF–3.5M

Select item 739335113.

Histone deacetylase 3 controls lung alveolar macrophage development and homeostasis

Yi Yao, Queping Liu, Indra Adrianto, Xiaojun Wu, James Glassbrook, Namir Khalasawi, Congcong Yin, Qijun Yi, Zheng Dong, Frederic Geissmann, Li Zhou, Qing-Sheng Mi

Nat Commun. 2020; 11: 3822. Published online 2020 Jul 30. doi: 10.1038/s41467-020-17630-6

PMCID:: PMC7393351

Abstract Article PDF–2.9M

Select item 727489514.

A Critical Role for Estrogen-Related Receptor Signaling in Cardiac Maturation

Tomoya Sakamoto, Timothy R. Matsuura, Shibiao Wan, David M. Ryba, Junil Kim, Kyoung Jae Won, Ling Lai, Christopher Petucci, Nataliya Petrenko, Kiran Musunuru, Rick B. Vega, Daniel P. Kelly

Circ Res. Author manuscript; available in PMC 2021 Jun 5.

Published in final edited form as: Circ Res. 2020 Jun 5; 126(12): 1685–1702. Published online 2020 Mar 26. doi: 10.1161/CIRCRESAHA.119.316100

PMCID:: PMC7274895

Abstract Article PDF–2.7M

Select item 703934415.

Frontline Science: Acyl-CoA synthetase 1 exacerbates lipotoxic inflammasome activation in primary macrophages

Gowri Kalugotla, Li He, Kassandra J. Weber, Sabine Daemen, Abigail Reller, Babak Razani, Joel D. Schilling

J Leukoc Biol. Author manuscript; available in PMC 2020 Feb 24.

Published in final edited form as: J Leukoc Biol. 2019 Oct; 106(4): 803–814. Published online 2019 Jun 5. doi: 10.1002/JLB.3HI0219-045RR

PMCID:: PMC7039344

Abstract Article PDF–1.8M

Select item 655243816.

Defective fatty acid oxidation in mice with muscle-specific acyl-CoA synthetase 1 deficiency increases amino acid use and impairs muscle function

Liyang Zhao, Florencia Pascual, Lawrence Bacudio, Amanda L. Suchanek, Pamela A. Young, Lei O. Li, Sarah A. Martin, Joao-Paulo Camporez, Rachel J. Perry, Gerald I. Shulman, Eric L. Klett, Rosalind A. Coleman

J Biol Chem. 2019 May 31; 294(22): 8819–8833. Published online 2019 Apr 11. doi: 10.1074/jbc.RA118.006790

PMCID:: PMC6552438

Abstract Article PDF–3.6M

Select item 629804017.

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors

Hyeonwoo Kim, Christiane D. Wrann, Mark Jedrychowski, Sara Vidoni, Yukiko Kitase, Kenichi Nagano, Chenhe Zhou, Joshua Chou, Virginia-Jeni A. Parkman, Scott J. Novick, Timothy S. Strutzenberg, Bruce D. Pascal, Phuong T. Le, Daniel J. Brooks, Alexander M. Roche, Kaitlyn K. Gerber, Laura Mattheis, Wenjing Chen, Hua Tu, Mary L. Bouxsein, Patrick R. Griffin, Roland Baron, Clifford J. Rosen, Lynda F. Bonewald, Bruce M. Spiegelman

Cell. Author manuscript; available in PMC 2019 Dec 13.

Published in final edited form as: Cell. 2018 Dec 13; 175(7): 1756–1768.e17. doi: 10.1016/j.cell.2018.10.025

Correction in:: Cell. 2019 Jul 11; 178(2): 507–508.

PMCID:: PMC6298040

Abstract Article PDF–1.2M

Select item 620489018.

Long-chain acyl-CoA synthetase 1 interacts with key proteins that activate and direct fatty acids into niche hepatic pathways

Pamela A. Young, Can E. Senkal, Amanda L. Suchanek, Trisha J. Grevengoed, Dennis D. Lin, Liyang Zhao, Amanda E. Crunk, Eric L. Klett, Joachim Füllekrug, Lina M. Obeid, Rosalind A. Coleman

J Biol Chem. 2018 Oct 26; 293(43): 16724–16740. Published online 2018 Sep 6. doi: 10.1074/jbc.RA118.004049

PMCID:: PMC6204890

Abstract Article PDF–3.4M

Select item 618761619.

Proteolipid domains form in biomimetic and cardiac mitochondrial vesicles and are regulated by cardiolipin concentration but not monolyso-cardiolipin

Edward Ross Pennington, E. Madison Sullivan, Amy Fix, Sahil Dadoo, Tonya N. Zeczycki, Anita DeSantis, Uwe Schlattner, Rosalind A. Coleman, Adam J. Chicco, David A. Brown, Saame Raza Shaikh

J Biol Chem. 2018 Oct 12; 293(41): 15933–15946. Published online 2018 Aug 29. doi: 10.1074/jbc.RA118.004948

PMCID:: PMC6187616

Abstract Article PDF–2.5M

Select item 601542320.

Modeling the Transition From Decompensated to Pathological Hypertrophy

Florencia Pascual, Jonathan C. Schisler, Trisha J. Grevengoed, Monte S. Willis, Rosalind A. Coleman

J Am Heart Assoc. 2018 Apr 17; 7(8): e008293. Published online 2018 Apr 5. doi: 10.1161/JAHA.117.008293

PMCID:: PMC6015423

Abstract Article PDF–2.2M

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