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Items: 1 to 20 of 93

1.
HuR promotes castration-resistant prostate cancer progression by altering ERK5 activation via posttranscriptional regulation of BCAT1
Hang You, Guojing Song, Zhizhen Xu, Saipeng Chen, Wenhao Shen, Heting Liu, Bingqian Deng, Jun Li, Gang Huang
J Transl Med. 2024; 22: 178. Published online 2024 Feb 18. doi: 10.1186/s12967-024-04970-w
PMCID:
PMC10874581
AbstractArticlePDF–7.9M
2.
Docking protein 6 (DOK6) selectively docks the neurotrophic signaling transduction to restrain peripheral neuropathy
Yan Guo, Pan Xiang, Xiaojiao Sun, Wei Liu, Jiafeng Zhou, Bin Yin, Lin Hou, Boqin Qiang, Huiliang Li, Pengcheng Shu, Xiaozhong Peng
Signal Transduct Target Ther. 2024; 9: 32. Published online 2024 Feb 14. doi: 10.1038/s41392-024-01742-2
PMCID:
PMC10864363
AbstractArticlePDF–9.9M
3.
Aerobic exercise alters the melanoma microenvironment and modulates ERK5 S496 phosphorylation
Hannah Savage, Sumedha Pareek, Jonghae Lee, Riccardo Ballarò, Darlan Conterno Minussi, Karma Hayek, Mumina Sadullozoda, Brooke S. Lochmann, Jennifer L. McQuade, Emily C. LaVoy, Enrica Marmonti, Hetal Patel, Guangyu Wang, Masaki Imanishi, Sivareddy Kotla, Jun-ichi Abe, Keri Schadler
Cancer Immunol Res. Author manuscript; available in PMC 2024 Mar 1.
Published in final edited form as: Cancer Immunol Res. 2023 Sep 1; 11(9): 1168–1183. doi: 10.1158/2326-6066.CIR-22-0465
PMCID:
PMC10527747
AbstractArticlePDF–3.5M
4.
TRAF7 is an essential regulator of blood vessel integrity during mouse embryonic and neonatal development
Erdyni N. Tsitsikov, Khanh P. Phan, Yufeng Liu, Alla V. Tsytsykova, Mike Kinter, Lauren Selland, Lori Garman, Courtney Griffin, Ian F. Dunn
iScience. 2023 Aug 18; 26(8): 107474. Published online 2023 Jul 25. doi: 10.1016/j.isci.2023.107474
PMCID:
PMC10424150
AbstractArticlePDF–5.6M
5.
An ERK5-NRF2 axis mediates senescence-associated stemness and atherosclerosis
Jun-ichi Abe, Masaki Imanishi, Shengyu Li, Aijun Zhang, Kyung Ae Ko, Venkata S. K. Samanthapudi, Ling-Ling Lee, Angelica Paniagua Bojorges, Young Jin Gi, Brian P. Hobbs, Anita Deswal, Joerg Herrmann, Steven H. Lin, Eduardo N. Chini, Ying H. Shen, Keri L. Schadler, Thi-Hong-Minh Nguyen, Anisha A. Gupte, Cielito Reyes-Gibby, Sai-Ching J. Yeung, Rei J. Abe, Elizabeth A. Olmsted-Davis, Sunil Krishnan, Robert Dantzer, Nicolas L. Palaskas, John P. Cooke, Henry J. Pownall, Momoko Yoshimoto, Keigi Fujiwara, Dale J. Hamilton, Jared K. Burks, Guangyu Wang, Nhat-Tu Le, Sivareddy Kotla
Circ Res. Author manuscript; available in PMC 2024 Jun 23.
Published in final edited form as: Circ Res. 2023 Jun 23; 133(1): 25–44. Published online 2023 Jun 2. doi: 10.1161/CIRCRESAHA.122.322017
PMCID:
PMC10357365
AbstractArticlePDF–3.7M
6.
SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation–Phosphorylation Cross-talk
Valentina Lukinović, Simone Hausmann, Gael S. Roth, Clement Oyeniran, Tanveer Ahmad, Ning Tsao, Joshua R. Brickner, Alexandre G. Casanova, Florent Chuffart, Ana Morales Benitez, Jessica Vayr, Rebecca Rodell, Marianne Tardif, Pascal W.T.C. Jansen, Yohann Couté, Michiel Vermeulen, Pierre Hainaut, Pawel K. Mazur, Nima Mosammaparast, Nicolas Reynoird
Cancer Discov. 2022 Sep 2; 12(9): 2158–2179. Published online 2022 Jul 12. doi: 10.1158/2159-8290.CD-21-0205
PMCID:
PMC9437563
AbstractArticlePDF–9.5M
7.
An ERK5–KLF2 signalling module regulates early embryonic gene expression and telomere rejuvenation in stem cells
Helen A. Brown, Charles A.C. Williams, Houjiang Zhou, Diana Rios-Szwed, Rosalia Fernandez-Alonso, Saria Mansoor, Liam McMulkin, Rachel Toth, Robert Gourlay, Julien Peltier, Nora Dieguez-Martinez, Matthias Trost, Jose M. Lizcano, Marios P. Stavridis, Greg M. Findlay
Biochem J. 2021 Dec 10; 478(23): 4119–4136. Prepublished online 2021 Nov 15. Published online 2021 Dec 6. doi: 10.1042/BCJ20210646
PMCID:
PMC8718266
AbstractArticlePDF–9.6M
8.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
9.
Extracellular signal regulated kinase 5 promotes cell migration, invasion and lung metastasis in a FAK-dependent manner
Weiwei Jiang, Fangfang Cai, Huangru Xu, Yanyan Lu, Jia Chen, Jia Liu, Nini Cao, Xiangyu Zhang, Xiao Chen, Qilai Huang, Hongqin Zhuang, Zi-Chun Hua
Protein Cell. 2020 Nov; 11(11): 825–845. Published online 2020 Mar 6. doi: 10.1007/s13238-020-00701-1
PMCID:
PMC7647985
AbstractArticlePDF–5.2M
10.
Fluid Shear Stress Suppresses Osteoclast Differentiation in RAW264.7 Cells through Extracellular Signal-Regulated Kinase 5 (ERK5) Signaling Pathway
Chongwen Ma, Bin Geng, Xiaohui Zhang, Rui Li, Xinxin Yang, Yayi Xia
Med Sci Monit. 2020; 26: e918370-1–e918370-9. Published online 2020 Jan 8. doi: 10.12659/MSM.918370
PMCID:
PMC6977602
AbstractArticlePDF–1.2M
11.
ERK5 plays an essential role in gestational beta‐cell proliferation
Congde Chen, Suichun Wu, Xiaokun Lin, Dazhou Wu, Shane Fischbach, Xiangwei Xiao
Cell Prolif. 2018 Jun; 51(3): e12410. Published online 2017 Nov 21. doi: 10.1111/cpr.12410
PMCID:
PMC6528926
AbstractArticlePDF–1005K
12.
MAGI1 as a link between endothelial activation and ER stress drives atherosclerosis
Jun-ichi Abe, Kyung Ae Ko, Sivareddy Kotla, Yin Wang, Jesus Paez-Mayorga, Ik Jae Shin, Masaki Imanishi, Hang Thi Vu, Yunting Tao, Miguel M. Leiva-Juarez, Tamlyn N. Thomas, Jan L. Medina, Jong Hak Won, Yuka Fujii, Carolyn J. Giancursio, Elena McBeath, Ji-Hyun Shin, Liliana Guzman, Rei J. Abe, Jack Taunton, Naoki Mochizuki, William Faubion, John P. Cooke, Keigi Fujiwara, Scott E. Evans, Nhat-Tu Le
JCI Insight. 2019 Apr 4; 4(7): e125570. Published online 2019 Apr 4. doi: 10.1172/jci.insight.125570
PMCID:
PMC6483653
AbstractArticlePDF–19M
13.
ROS amplification drives mouse spermatogonial stem cell self-renewal
Hiroko Morimoto, Mito Kanastu-Shinohara, Narumi Ogonuki, Satoshi Kamimura, Atsuo Ogura, Chihiro Yabe-Nishimura, Yoshifumi Mori, Takeshi Morimoto, Satoshi Watanabe, Kinya Otsu, Takuya Yamamoto, Takashi Shinohara
Life Sci Alliance. 2019 Apr; 2(2): e201900374. Published online 2019 Apr 2. doi: 10.26508/lsa.201900374
PMCID:
PMC6448598
AbstractArticlePDF–2.5M
14.
ERK5 Knockdown Generates Mouse Leukemia Cells with Low MHC Class I Levels That Activate NK Cells and Block Tumorigenesis
Seyma Charni, Juan Ignacio Aguilo, Johan Garaude, Geoffroy de Bettignies, Chantal Jacquet, Robert A. Hipskind, Dinah Singer, Alberto Anel, Martin Villalba
J Immunol. Author manuscript; available in PMC 2018 Dec 30.
Published in final edited form as: J Immunol. 2009 Mar 15; 182(6): 3398–3405. doi: 10.4049/jimmunol.0803006
PMCID:
PMC6311211
AbstractArticlePDF–2.9M
15.
Hypoxia and Ischemia Promote a Maladaptive Platelet Phenotype
Scott J. Cameron, Doran S. Mix, Sara K. Ture, Rachel A. Schmidt, Amy Mohan, Daphne Pariser, Michael C. Stoner, Punit Shah, Lijun Chen, Hui Zhang, David J. Field, Kristina L. Modjeski, Sandra Toth, Craig N. Morrell
Arterioscler Thromb Vasc Biol. 2018 Jul; 38(7): 1594–1606. Published online 2018 Apr 5. doi: 10.1161/ATVBAHA.118.311186
PMCID:
PMC6023774
AbstractArticlePDF–1.3M
16.
Myeloid ERK5 deficiency suppresses tumor growth by blocking protumor macrophage polarization via STAT3 inhibition
Emanuele Giurisato, Qiuping Xu, Silvia Lonardi, Brian Telfer, Ilaria Russo, Adam Pearson, Katherine G. Finegan, Wenbin Wang, Jinhua Wang, Nathanael S. Gray, William Vermi, Zhengui Xia, Cathy Tournier
Proc Natl Acad Sci U S A. 2018 Mar 20; 115(12): E2801–E2810. Published online 2018 Mar 5. doi: 10.1073/pnas.1707929115
PMCID:
PMC5866536
AbstractArticlePDF–1.9M
17.
Extracellular signal–regulated kinase 5 promotes acute cellular and systemic inflammation
Kevin Wilhelmsen, Fengyun Xu, Katherine Farrar, Alphonso Tran, Samira Khakpour, Shirin Sundar, Arun Prakash, Jinhua Wang, Nathanael S. Gray, Judith Hellman
Sci Signal. Author manuscript; available in PMC 2017 Dec 18.
Published in final edited form as: Sci Signal. 2015 Aug 25; 8(391): ra86. Published online 2015 Aug 25. doi: 10.1126/scisignal.aaa3206
PMCID:
PMC5734625
AbstractArticlePDF–885K
18.
Analysis of Nkx3.1:Cre-driven Erk5 deletion reveals a profound spinal deformity which is linked to increased osteoclast activity
Carolyn J. Loveridge, Rob J. van ’t Hof, Gemma Charlesworth, Ayala King, Ee Hong Tan, Lorraine Rose, Anna Daroszewska, Amanda Prior, Imran Ahmad, Michelle Welsh, Ernest J. Mui, Catriona Ford, Mark Salji, Owen Sansom, Karen Blyth, Hing Y. Leung
Sci Rep. 2017; 7: 13241. Published online 2017 Oct 16. doi: 10.1038/s41598-017-13346-8
PMCID:
PMC5643304
AbstractArticlePDF–7.4M
19.
Metabolic stress-induced cardiomyopathy is caused by mitochondrial dysfunction due to attenuated Erk5 signaling
Wei Liu, Andrea Ruiz-Velasco, Shoubao Wang, Saba Khan, Min Zi, Andreas Jungmann, Maria Dolores Camacho-Muñoz, Jing Guo, Guanhua Du, Liping Xie, Delvac Oceandy, Anna Nicolaou, Gina Galli, Oliver J. Müller, Elizabeth J. Cartwright, Yong Ji, Xin Wang
Nat Commun. 2017; 8: 494. Published online 2017 Sep 8. doi: 10.1038/s41467-017-00664-8
PMCID:
PMC5591279
AbstractArticlePDF–2.4M
20.
CHOP Deficiency Ameliorates ERK5 Inhibition-Mediated Exacerbation of Streptozotocin-Induced Hyperglycemia and Pancreatic β-Cell Apoptosis
Dae-Hwan Nam, Jung-Hwa Han, Jae Hyang Lim, Kwon Moo Park, Chang-Hoon Woo
Mol Cells. 2017 Jul 31; 40(7): 457–465. Published online 2017 Jul 6. doi: 10.14348/molcells.2017.2296
PMCID:
PMC5547215
AbstractArticlePDF–2.4M

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