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Select item 109127691.

A ubiquitous GC content signature underlies multimodal mRNA regulation by DDX3X

Ziad Jowhar, Albert Xu, Srivats Venkataramanan, Francesco Dossena, Mariah L Hoye, Debra L Silver, Stephen N Floor, Lorenzo Calviello

Mol Syst Biol. 2024 Mar; 20(3): 276–290. Published online 2024 Jan 25. doi: 10.1038/s44320-024-00013-0

PMCID:: PMC10912769

Abstract Article PDF–3.8M

Select item 107345502.

Cell-type-specific need of Ddx3 and PACT for interferon induction by RNA viruses

Nikhil Sharma, Patricia Kessler, Ganes C. Sen

J Virol. 2023 Dec; 97(12): e01304-23. Published online 2023 Nov 20. doi: 10.1128/jvi.01304-23

PMCID:: PMC10734550

Abstract Article PDF–913K

Select item 104336303.

miR-181a-5p targets DDX3X to inhibit the progression of osteoarthritis via NF-ΚB signaling pathway

Peng Zhao, Guobin Ma, Lintong Ma

J Orthop Surg Res. 2023; 18: 606. Published online 2023 Aug 16. doi: 10.1186/s13018-023-04073-0

PMCID:: PMC10433630

Abstract Article PDF–2.0M

Select item 103228694.

Hepatocyte DDX3X protects against drug-induced acute liver injury via controlling stress granule formation and oxidative stress

Tingting Luo, Suzhen Yang, Tianming Zhao, Hanlong Zhu, Chunyan Chen, Xiaoxiao Shi, Di Chen, Kai Wang, Kang Jiang, Dan Xu, Ming Cheng, Juan Li, Wenting Li, Weijun Xu, Lin Zhou, Mingzuo Jiang, Bing Xu

Cell Death Dis. 2023 Jul; 14(7): 400. Published online 2023 Jul 6. doi: 10.1038/s41419-023-05913-x

PMCID:: PMC10322869

Abstract Article PDF–4.9M

Select item 96038605.

The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3

Laura Sánchez-Bellver, Andrea Férriz-Gordillo, Marc Carrillo-Pz, Laura Rabanal, Francesc R. Garcia-Gonzalo, Gemma Marfany

Int J Mol Sci. 2022 Oct; 23(20): 12527. Published online 2022 Oct 19. doi: 10.3390/ijms232012527

PMCID:: PMC9603860

Abstract Article PDF–3.4M

Select item 95449566.

MRNIP interacts with sex body chromatin to support meiotic progression, spermatogenesis, and male fertility in mice

Samina Kazi, Julio M. Castañeda, Audrey Savolainen, Yiding Xu, Ning Liu, Huanyu Qiao, Ramiro Ramirez‐Solis, Kaori Nozawa, Zhifeng Yu, Martin M. Matzuk, Renata Prunskaite‐Hyyryläinen

FASEB J. 2022 Sep; 36(9): e22479. Published online 2022 Aug 3. doi: 10.1096/fj.202101168RR

PMCID:: PMC9544956

Abstract Article PDF–9.8M

Select item 92396847.

Aberrant cortical development is driven by impaired cell cycle and translational control in a DDX3X syndrome model

Mariah L Hoye, Lorenzo Calviello, Abigail J Poff, Nna-Emeka Ejimogu, Carly R Newman, Maya D Montgomery, Jianhong Ou, Stephen N Floor, Debra L Silver

eLife. 2022; 11: e78203. Published online 2022 Jun 28. doi: 10.7554/eLife.78203

PMCID:: PMC9239684

Abstract Article PDF–14M

Select item 85710438.

Developmental and behavioral phenotypes in a mouse model of DDX3X syndrome

Andrea Boitnott, Marta Garcia-Forn, Dévina C Ung, Kristi Niblo, Danielle Mendonca, Yeaji Park, Michael Flores, Sylvia Maxwell, Jacob Ellegood, Lily R Qiu, Dorothy E Grice, Jason P Lerch, Mladen-Roko Rasin, Joseph D Buxbaum, Elodie Drapeau, Silvia De Rubeis

Biol Psychiatry. Author manuscript; available in PMC 2022 Dec 1.

Published in final edited form as: Biol Psychiatry. 2021 Dec 1; 90(11): 742–755. Published online 2021 Jun 7. doi: 10.1016/j.biopsych.2021.05.027

PMCID:: PMC8571043

Abstract Article PDF–2.1M

Select item 83132399.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 826661710.

Matrix-screening reveals a vast potential for direct protein-protein interactions among RNA binding proteins

Benjamin Lang, Jae-Seong Yang, Mireia Garriga-Canut, Silvia Speroni, Moritz Aschern, Maria Gili, Tobias Hoffmann, Gian Gaetano Tartaglia, Sebastian P Maurer

Nucleic Acids Res. 2021 Jul 9; 49(12): 6702–6721. Published online 2021 Jun 16. doi: 10.1093/nar/gkab490

PMCID:: PMC8266617

Abstract Article PDF–4.0M

Select item 821059611.

Demalonylation of DDX3 by Sirtuin 5 promotes antiviral innate immune responses

Xingying He, Tianliang Li, Kewei Qin, Shiyuan Luo, Zhenjie Li, Qingqing Ji, Honghao Song, Huyang He, Hao Tang, Chaofeng Han, Hongjiao Li, Yan Luo

Theranostics. 2021; 11(15): 7235–7246. Published online 2021 May 24. doi: 10.7150/thno.52934

PMCID:: PMC8210596

Abstract Article PDF–1.7M

Select item 808605512.

Galactosaminogalactan activates the inflammasome to provide host protection

Benoit Briard, Thierry Fontaine, Parimal Samir, David E. Place, Laetitia Muszkieta, R.K. Subbarao Malireddi, Rajendra Karki, Shelbi Christgen, Perrine Bomme, Peter Vogel, Rémi Beau, Emilia Mellado, Oumaima Ibrahim-Granet, Bernard Henrissat, Ravi C Kalathur, Cam Robinson, Jean-Paul Latgé, Thirumala-Devi Kanneganti

Nature. Author manuscript; available in PMC 2021 Jun 2.

Published in final edited form as: Nature. 2020 Dec; 588(7839): 688–692. Published online 2020 Dec 2. doi: 10.1038/s41586-020-2996-z

Correction in:: Nature. 2020 Dec 21

PMCID:: PMC8086055

Abstract Article PDF–4.4M

Select item 808191713.

DDX3X coordinates host defense against influenza virus by activating the NLRP3 inflammasome and type I interferon response

Sannula Kesavardhana, Parimal Samir, Min Zheng, R.K. Subbarao Malireddi, Rajendra Karki, Bhesh Raj Sharma, David E. Place, Benoit Briard, Peter Vogel, Thirumala-Devi Kanneganti

J Biol Chem. 2021 Jan-Jun; 296: 100579. Published online 2021 Mar 23. doi: 10.1016/j.jbc.2021.100579

PMCID:: PMC8081917

Abstract Article PDF–2.6M

Select item 793877014.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 748390815.

DDX3X suppresses the susceptibility of hindbrain lineages to medulloblastoma

Deanna M. Patmore, Amir Jassim, Erica Nathan, Reuben J. Gilbertson, Daniel Tahan, Nadin Hoffmann, Yiai Tong, Kyle S. Smith, Thirumala-Devi Kanneganti, Hiromichi Suzuki, Michael D. Taylor, Paul Northcott, Richard J. Gilbertson

Dev Cell. Author manuscript; available in PMC 2021 Aug 24.

Published in final edited form as: Dev Cell. 2020 Aug 24; 54(4): 455–470.e5. Published online 2020 Jun 17. doi: 10.1016/j.devcel.2020.05.027

PMCID:: PMC7483908

Abstract Article PDF–1.7M

Select item 741599116.

BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)

Kou Motani, Hidetaka Kosako

J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323

PMCID:: PMC7415991

Abstract Article PDF–2.0M

Select item 733128517.

Pathogenic DDX3X mutations impair RNA metabolism and neurogenesis during fetal cortical development

Ashley L. Lennox, Mariah L. Hoye, Ruiji Jiang, Bethany L. Johnson-Kerner, Lindsey A. Suit, Srivats Venkataramanan, Charles J. Sheehan, Fernando C. Alsina, Brieana Fregeau, Kimberly A. Aldinger, Ching Moey, Iryna Lobach, Alexandra Afenjar, Dusica Babovic-Vuksanovic, Stéphane Bézieau, Patrick R. Blackburn, Jens Bunt, Lydie Burglen, Philippe M. Campeau, Perrine Charles, Brian H.Y. Chung, Benjamin Cogné, Cynthia Curry, Maria Daniela D’Agostino, Nataliya Di Donato, Laurence Faivre, Delphine Héron, A. Micheil Innes, Bertrand Isidor, Boris Keren, Amy Kimball, Eric W. Klee, Paul Kuentz, Sébastien Küry, Dominique Martin-Coignard, Ghayda Mirzaa, Cyril Mignot, Noriko Miyake, Naomichi Matsumoto, Atsushi Fujita, Caroline Nava, Mathilde Nizon, Diana Rodriguez, Lot Snijders Blok, Christel Thauvin-Robinet, Julien Thevenon, Marie Vincent, Alban Ziegler, William Dobyns, Linda J. Richards, A. James Barkovich, Stephen N. Floor, Debra L. Silver, Elliott H. Sherr

Neuron. Author manuscript; available in PMC 2021 May 6.

Published in final edited form as: Neuron. 2020 May 6; 106(3): 404–420.e8. Published online 2020 Mar 4. doi: 10.1016/j.neuron.2020.01.042

PMCID:: PMC7331285

Abstract Article PDF–3.2M

Select item 698028418.

DDX3X acts as a live-or-die checkpoint in stressed cells by regulating NLRP3 inflammasome

Parimal Samir, Sannula Kesavardhana, Deanna M. Patmore, Sebastien Gingras, R. K. Subbarao Malireddi, Rajendra Karki, Clifford S. Guy, Benoit Briard, David E. Place, Anannya Bhattacharya, Bhesh raj Sharma, Amanda Nourse, Sharon V. King, Aaron Pitre, Amanda R. Burton, Stephane Pelletier, Richard J. Gilbertson, Thirumala-Devi Kanneganti

Nature. Author manuscript; available in PMC 2020 Mar 11.

Published in final edited form as: Nature. 2019 Sep; 573(7775): 590–594. Published online 2019 Sep 11. doi: 10.1038/s41586-019-1551-2

PMCID:: PMC6980284

Abstract Article PDF–5.6M

Select item 672539419.

Telencephalic Embryonic Subtractive Sequences: A Unique Collection of Neurodevelopmental Genes

Alessandro Bulfone, Pietro Carotenuto, Andrea Faedo, Veruska Aglio, Livia Garzia, Anna Maria Bello, Andrea Basile, Alessandra Andrè, Massimo Cocchia, Ombretta Guardiola, Andrea Ballabio, John L. R. Rubenstein, Massimo Zollo

J Neurosci. 2005 Aug 17; 25(33): 7586–7600. doi: 10.1523/JNEUROSCI.0522-05.2005

PMCID:: PMC6725394

Abstract Article PDF–682K

Select item 670556320.

DDX3 Modulates Neurite Development via Translationally Activating an RNA Regulon Involved in Rac1 Activation

Hung-Hsi Chen, Hsin-I Yu, Woan-Yuh Tarn

J Neurosci. 2016 Sep 21; 36(38): 9792–9804. doi: 10.1523/JNEUROSCI.4603-15.2016

PMCID:: PMC6705563

Abstract Article PDF–4.2M

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