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Select item 111096341.

Deficiency of Nuclear Receptor Coactivator 3 Aggravates Diabetic Kidney Disease by Impairing Podocyte Autophagy

Yaru Xie, Qian Yuan, Xinyi Cao, Yang Qiu, Jieyu Zeng, Yiling Cao, Yajuan Xie, Xianfang Meng, Kun Huang, Fan Yi, Chun Zhang

Adv Sci (Weinh) 2024 May; 11(19): 2308378. Published online 2024 Mar 14. doi: 10.1002/advs.202308378

PMCID:: PMC11109634

Abstract Article PDF–9.7M

Select item 109176602.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 103242783.

USP24-dependent stabilization of Runx2 recruits a p300/NCOA3 complex to transactivate ADAMTS genes and promote degeneration of intervertebral disc in chronic inflammation mice

Xingguo Li, Jun Zhang, Bing Wang, Chao Chen, Enyu Zhang, Zhengpin Lv, Qicong He, Yaoquan Hu, Xuenan Wang, Fan Zhang

Biol Direct. 2023; 18: 37. Published online 2023 Jul 6. doi: 10.1186/s13062-023-00395-5

PMCID:: PMC10324278

Abstract Article PDF–2.7M

Select item 102660154.

Steroid receptor coactivator 3 is a key modulator of regulatory T cell–mediated tumor evasion

Sang Jun Han, Prashi Jain, Yosef Gilad, Yan Xia, Nuri Sung, Mi Jin Park, Adam M. Dean, Rainer B. Lanz, Jianming Xu, Clifford C. Dacso, David M. Lonard, Bert W. O'Malley

Proc Natl Acad Sci U S A. 2023 Jun 6; 120(23): e2221707120. Published online 2023 May 30. doi: 10.1073/pnas.2221707120

PMCID:: PMC10266015

Abstract Article PDF–6.8M

Select item 100910775.

NCoA3 upregulation in breast cancer‑associated adipocytes elicits an inflammatory profile

María Cecilia Lira, Francisco D. Rosa, Ignacio Aiello, Mileni Soares Machado, Alejandra G. Palma, Leonardo Paz, María Cecilia Salazar Güemes, Silvia Burlando, Pablo J. Azurmendi, Natalia Paladino, Mónica A. Costas, María fernanda Rubio

Oncol Rep. 2023 May; 49(5): 105. Published online 2023 Apr 3. doi: 10.3892/or.2023.8542

PMCID:: PMC10091077

Abstract Article PDF–9.6M

Select item 96206276.

Steroid receptor coactivator-3 inhibition generates breast cancer antitumor immune microenvironment

Sang Jun Han, Nuri Sung, Jin Wang, Bert W. O’Malley, David M. Lonard

Breast Cancer Res. 2022; 24: 73. Published online 2022 Oct 31. doi: 10.1186/s13058-022-01568-2

PMCID:: PMC9620627

Abstract Article PDF–8.3M

Select item 95765067.

SRC-3 deficiency prevents atherosclerosis development by decreasing endothelial ICAM-1 expression to attenuate macrophage recruitment

Wenbo Chen, Wuyang Zheng, Shixiao Liu, Qiang Su, Kangxi Ding, Ziguan Zhang, Ping Luo, Yong Zhang, Jianming Xu, Chundong Yu, Weihua Li, Zhengrong Huang

Int J Biol Sci. 2022; 18(15): 5978–5993. Published online 2022 Oct 3. doi: 10.7150/ijbs.74864

PMCID:: PMC9576506

Abstract Article PDF–3.4M

Select item 89587218.

Defining the mammalian coactivation of hepatic 12-h clock and lipid metabolism

Huan Meng, Naomi M. Gonzales, Sung Yun Jung, Yue Lu, Nagireddy Putluri, Bokai Zhu, Clifford C. Dacso, David M. Lonard, Bert W. O’Malley

Cell Rep. Author manuscript; available in PMC 2022 Mar 28.

Published in final edited form as: Cell Rep. 2022 Mar 8; 38(10): 110491. doi: 10.1016/j.celrep.2022.110491

PMCID:: PMC8958721

Abstract Article PDF–3.2M

Select item 87633179.

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1–CoREST interactome during embryonic stem cell differentiation

Claire E. Barnes, David M. English, Megan Broderick, Mark O. Collins, Shaun M. Cowley

Mol Omics. 2022 Jan 17; 18(1): 31–44. Published online 2021 Oct 14. doi: 10.1039/d1mo00236h

PMCID:: PMC8763317

Abstract Article

Select item 864339210.

Steroid Receptor Coactivator 3 Regulates Synaptic Plasticity and Hippocampus-dependent Memory

Hai-Long Zhang, Bing Zhao, Pin Yang, Yin-Quan Du, Wei Han, Jianming Xu, Dong-Min Yin

Neurosci Bull. 2021 Dec; 37(12): 1645–1657. Published online 2021 Jul 6. doi: 10.1007/s12264-021-00741-5

PMCID:: PMC8643392

Abstract Article PDF–5.8M

Select item 858063811.

SRC-3 Knockout Attenuates Myocardial Injury Induced by Chronic Intermittent Hypoxia in Mice

Wanyu Wang, Hongbo Gu, Weihua Li, Yihua Lin, Xiangyang Yao, Wen Luo, Fang Lu, Shenhui Huang, Yonghong Shi, Zhengrong Huang

Oxid Med Cell Longev. 2021; 2021: 6372430. Published online 2021 Nov 3. doi: 10.1155/2021/6372430

PMCID:: PMC8580638

Abstract Article PDF–2.4M

Select item 858049012.

17β-Estradiol Attenuates Intracerebral Hemorrhage-Induced Blood–Brain Barrier Injury and Oxidative Stress Through SRC3-Mediated PI3K/Akt Signaling Pathway in a Mouse Model

Han Xiao, Jianyang Liu, Jialin He, Ziwei Lan, Mingyang Deng, Zhiping Hu

ASN Neuro. 2021 Jan-Dec; 13: 17590914211038443. Published online 2021 Sep 7. doi: 10.1177/17590914211038443

PMCID:: PMC8580490

Abstract Article PDF–2.1M

Select item 839051713.

SRC3 acetylates calmodulin in the mouse brain to regulate synaptic plasticity and fear learning

Hai-Long Zhang, Wei Han, Yin-Quan Du, Bing Zhao, Pin Yang, Dong-Min Yin

J Biol Chem. 2021 Sep; 297(3): 101044. Published online 2021 Aug 4. doi: 10.1016/j.jbc.2021.101044

PMCID:: PMC8390517

Abstract Article PDF–2.7M

Select item 837379514.

An AIB1 isoform alters enhancer access and enables progression of early stage triple-negative breast cancer

Ghada M Sharif, Moray J Campbell, Apsra Nasir, Surojeet Sengupta, Garrett T Graham, Max H Kushner, William B Kietzman, Marcel O Schmidt, Gray W Pearson, Olivier Loudig, Susan Fineberg, Anton Wellstein, Anna T. Riegel

Cancer Res. Author manuscript; available in PMC 2022 Feb 15.

Published in final edited form as: Cancer Res. 2021 Aug 15; 81(16): 4230–4241. Published online 2021 Jun 16. doi: 10.1158/0008-5472.CAN-20-3625

PMCID:: PMC8373795

Abstract Article PDF–2.8M

Select item 793877015.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 787328116.

Steroid receptor coactivator 3 (SRC-3/AIB1) is enriched and functional in mouse and human Tregs

Bryan C. Nikolai, Prashi Jain, David L. Cardenas, Brian York, Qin Feng, Neil J. McKenna, Subhamoy Dasgupta, David M. Lonard, Bert W. O’Malley

Sci Rep. 2021; 11: 3441. Published online 2021 Feb 9. doi: 10.1038/s41598-021-82945-3

PMCID:: PMC7873281

Abstract Article PDF–2.7M

Select item 782311117.

NCOA3 identified as a new candidate to explain autosomal dominant progressive hearing loss

R Salazar-Silva, Vitor Lima Goes Dantas, Leandro Ucela Alves, Ana Carla Batissoco, Jeanne Oiticica, Elizabeth A Lawrence, Abdelwahab Kawafi, Yushi Yang, Fernanda Stávale Nicastro, Beatriz Caiuby Novaes, Chrissy Hammond, Erika Kague, R C Mingroni-Netto

Hum Mol Genet. 2020 Nov 15; 29(22): 3691–3705. Published online 2020 Dec 17. doi: 10.1093/hmg/ddaa240