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Items: 1 to 20 of 106

1.
The calcium-sensing-receptor (CaSR) in adipocytes contributes to sex-differences in the susceptibility to high fat diet induced obesity and atherosclerosis
Svenja Adam, Sanne L. Maas, Rosanna Huchzermeier, Leonida Rakateli, Kathrin Abschlag, Mathias Hohl, Liangliang Liao, Matthias Bartneck, Margee Teunissen, Kristiaan Wouters, Donato Santovito, Joachim Jankowski, Erik A.L. Biessen, Emiel P.C. van der Vorst
eBioMedicine. 2024 Sep; 107: 105293. Published online 2024 Aug 14. doi: 10.1016/j.ebiom.2024.105293
PMCID:
PMC11379552
AbstractArticlePDF–2.4M
2.
A novel mouse model for familial hypocalciuric hypercalcemia (FHH1) reveals PTH-dependent and independent CaSR defects
Catharina J. Küng, Arezoo Daryadel, Rocio Fuente, Betül Haykir, Martin Hrabĕ de Angelis, Nati Hernando, Isabel Rubio-Aliaga, Carsten A. Wagner
Pflugers Arch. 2024; 476(5): 833–845. Published online 2024 Feb 22. doi: 10.1007/s00424-024-02927-y
PMCID:
PMC11033242
AbstractArticlePDF–6.5M
3.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
4.
Calcium/calcimimetic via calcium-sensing receptor ameliorates cholera toxin-induced secretory diarrhea in mice
Lie-Qi Tang, Johnathan Fraebel, Shi Jin, Steven P Winesett, Jane Harrell, Wen-Han Chang, Sam Xianjun Cheng
World J Gastroenterol. 2024 Jan 21; 30(3): 268–279. Published online 2024 Jan 21. doi: 10.3748/wjg.v30.i3.268
PMCID:
PMC10835527
AbstractArticlePDF–7.2M
5.
Role of calcium-sensing receptor in regulating activation susceptibility of postovulatory aging mouse oocytes
Rui YANG, Chang-Li JI, Min ZHANG, Jie ZHANG, Hong-Jie YUAN, Ming-Jiu LUO, Guang-Zhong JIAO, Jing-He TAN
J Reprod Dev. 2023 Aug; 69(4): 185–191. Published online 2023 May 26. doi: 10.1262/jrd.2023-026
PMCID:
PMC10435528
AbstractArticlePDF–3.9M
6.
Differential parathyroid and kidney Ca2+-sensing receptor activation in autosomal dominant hypocalcemia 1
Wouter H. van Megen, Rebecca Siu Ga Tan, R. Todd Alexander, Henrik Dimke
EBioMedicine. 2022 Apr; 78: 103947. Published online 2022 Mar 18. doi: 10.1016/j.ebiom.2022.103947
PMCID:
PMC8935519
AbstractArticlePDF–3.0M
7.
Calcium-Sensing Receptor and CPAP-Induced Neonatal Airway Hyperreactivity in Mice
Catherine A Mayer, Benjamin Roos, Jacob Teske, Natalya Wells, Richard J Martin, Wenhan Chang, Christina M Pabelick, YS Prakash, Peter M MacFarlane
Pediatr Res. Author manuscript; available in PMC 2022 Jun 17.
Published in final edited form as: Pediatr Res. 2022 May; 91(6): 1391–1398. Published online 2021 May 6. doi: 10.1038/s41390-021-01540-4
PMCID:
PMC8571113
AbstractArticlePDF–1.0M
8.
The mTORC2 Regulator Homer1 Modulates Protein Levels and Sub-Cellular Localization of the CaSR in Osteoblast-Lineage Cells
Mark S. Rybchyn, Tara Clare Brennan-Speranza, David Mor, Zhiqiang Cheng, Wenhan Chang, Arthur D. Conigrave, Rebecca S. Mason
Int J Mol Sci. 2021 Jun; 22(12): 6509. Published online 2021 Jun 17. doi: 10.3390/ijms22126509
PMCID:
PMC8234890
AbstractArticlePDF–4.6M
9.
Ap2s1 mutation causes hypercalcaemia in mice and impairs interaction between calcium-sensing receptor and adaptor protein-2
Fadil M Hannan, Mark Stevenson, Asha L Bayliss, Victoria J Stokes, Michelle Stewart, Kreepa G Kooblall, Caroline M Gorvin, Gemma Codner, Lydia Teboul, Sara Wells, Rajesh V Thakker
Hum Mol Genet. 2021 May 15; 30(10): 880–892. Published online 2021 Mar 17. doi: 10.1093/hmg/ddab076
PMCID:
PMC8165646
AbstractArticlePDF–1.1M
10.
Enhanced excitability of cortical neurons in low-divalent solutions is primarily mediated by altered voltage-dependence of voltage-gated sodium channels
Briana J Martiszus, Timur Tsintsadze, Wenhan Chang, Stephen M Smith
eLife. 2021; 10: e67914. Published online 2021 May 11. doi: 10.7554/eLife.67914
PMCID:
PMC8163501
AbstractArticlePDF–2.1M
11.
Adipocyte calcium sensing receptor is not involved in visceral adipose tissue inflammation or atherosclerosis development in hyperlipidemic Apoe−/− mice
Sai Sahana Sundararaman, Linsey J. F. Peters, Yvonne Jansen, Selin Gencer, Yi Yan, Sumra Nazir, Andrea Bonnin Marquez, Florian Kahles, Michael Lehrke, Erik A. L. Biessen, Joachim Jankowski, Christian Weber, Yvonne Döring, Emiel P. C. van der Vorst
Sci Rep. 2021; 11: 10409. Published online 2021 May 17. doi: 10.1038/s41598-021-89893-y
PMCID:
PMC8128899
AbstractArticlePDF–2.9M
12.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
13.
Aberrant upregulation of CaSR promotes pathological new bone formation in ankylosing spondylitis
Xiang Li, Siwen Chen, Zaiying Hu, Dongying Chen, Jianru Wang, Zemin Li, Zihao Li, Haowen Cui, Guo Dai, Lei Liu, Haitao Wang, Kuibo Zhang, Zhaomin Zheng, Zhongping Zhan, Hui Liu
EMBO Mol Med. 2020 Dec 7; 12(12): e12109. Published online 2020 Dec 1. doi: 10.15252/emmm.202012109
PMCID:
PMC7721361
AbstractArticlePDF–6.0M
14.
Calcium-Sensing Receptors in Chondrocytes and Osteoblasts Are Required for Callus Maturation and Fracture Healing in Mice
Zhiqiang Cheng, Alfred Li, Chia-Ling Tu, Christian Santa Maria, Nicholas Szeto, Amanda Herberger, Tsui-Hua Chen, Fuqing Song, Jiali Wang, Xiaodong Liu, Dolores M Shoback, Wenhan Chang
J Bone Miner Res. Author manuscript; available in PMC 2020 Nov 29.
Published in final edited form as: J Bone Miner Res. 2020 Jan; 35(1): 143–154. Published online 2019 Oct 18. doi: 10.1002/jbmr.3864
PMCID:
PMC7700777
AbstractArticlePDF–3.0M
15.
Heteromeric TRPV4/TRPC1 channels mediate calcium-sensing receptor-induced relaxations and nitric oxide production in mesenteric arteries: comparative study using wild-type and TRPC1−/- mice
Harry Z.E. Greenberg, Simonette R.E. Carlton-Carew, Alexander K. Zargaran, Kazi S. Jahan, Lutz Birnbaumer, Anthony P. Albert
Channels (Austin) 2019; 13(1): 410–423. Published online 2019 Oct 11. doi: 10.1080/19336950.2019.1673131
PMCID:
PMC7426016
AbstractArticlePDF–2.0M
16.
The Calcium-Sensing Receptor Regulates Plasma Membrane Calcium Adenosine Triphosphatase Isoform 2 Activity in Mammary Epithelial Cells: A Mechanism for Calcium-Regulated Calcium Transport into Milk
Joshua N. VanHouten, Margaret C. Neville, John J. Wysolmerski
Endocrinology. 2007 Dec 1; 148(12): 5943–5954. doi: 10.1210/en.2007-0850
PMCID:
PMC7108505
AbstractArticlePDF–592K
17.
Calcium-sensing receptor deletion in the mouse esophagus alters barrier function
Nazih L. Nakhoul, Chia-Ling Tu, Karen L. Brown, M. Toriqul Islam, Anna G. Hodges, Solange M. Abdulnour-Nakhoul
Am J Physiol Gastrointest Liver Physiol. 2020 Jan 1; 318(1): G144–G161. Published online 2019 Nov 11. doi: 10.1152/ajpgi.00021.2019
PMCID:
PMC6985844
AbstractArticle
18.
Calcium‐sensing receptor regulates intestinal dipeptide absorption via Ca2+ signaling and IKCa activation
Jingyu Xu, Andre Zeug, Brigitte Riederer, Sunil Yeruva, Oliver Griesbeck, Hannelore Daniel, Biguang Tuo, Evgeni Ponimaskin, Hui Dong, Ursula Seidler
Physiol Rep. 2020 Jan; 8(1): e14337. Published online 2020 Jan 21. doi: 10.14814/phy2.14337
PMCID:
PMC6971415
AbstractArticlePDF–2.1M
19.
Homer1 mediates CaSR-dependent activation of mTOR complex 2 and initiates a novel pathway for AKT-dependent β-catenin stabilization in osteoblasts
Mark S. Rybchyn, Kazi S. Islam, Tara C. Brennan-Speranza, Zhiqiang Cheng, Sarah C. Brennan, Wenhan Chang, Rebecca S. Mason, Arthur David Conigrave
J Biol Chem. 2019 Nov 1; 294(44): 16337–16350. Published online 2019 Sep 16. doi: 10.1074/jbc.RA118.006587
PMCID:
PMC6827303
AbstractArticlePDF–4.2M
20.
Phosphate acts directly on the calcium-sensing receptor to stimulate parathyroid hormone secretion
Patricia P. Centeno, Amanda Herberger, Hee-Chang Mun, Chialing Tu, Edward F. Nemeth, Wenhan Chang, Arthur D. Conigrave, Donald T. Ward
Nat Commun. 2019; 10: 4693. Published online 2019 Oct 16. doi: 10.1038/s41467-019-12399-9
PMCID:
PMC6795806
AbstractArticlePDF–1.4M

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