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Select item 114915401.

Morphological, electrophysiological, and molecular alterations in foetal noncompacted cardiomyopathy induced by disruption of ROCK signalling

David Sedmera, Veronika Olejnickova, Barbora Sankova, Hana Kolesova, Martin Bartos, Alena Kvasilova, Lauren C. Phillips, Simon D. Bamforth, Helen M. Phillips

Front Cell Dev Biol. 2024; 12: 1471751. Published online 2024 Oct 7. doi: 10.3389/fcell.2024.1471751

PMCID:: PMC11491540

Abstract Article PDF–10M

Select item 114526232.

The G4 resolvase Dhx36 modulates cardiomyocyte differentiation and ventricular conduction system development

Pablo Gómez-del Arco, Joan Isern, Daniel Jimenez-Carretero, Dolores López-Maderuelo, Rebeca Piñeiro-Sabarís, Fadoua El Abdellaoui-Soussi, Carlos Torroja, María Linarejos Vera-Pedrosa, Mercedes Grima-Terrén, Alberto Benguria, Ana Simón-Chica, Antonio Queiro-Palou, Ana Dopazo, Fátima Sánchez-Cabo, José Jalife, José Luis de la Pompa, David Filgueiras-Rama, Pura Muñoz-Cánoves, Juan Miguel Redondo

Nat Commun. 2024; 15: 8602. Published online 2024 Oct 4. doi: 10.1038/s41467-024-52809-1

PMCID:: PMC11452623

Abstract Article PDF–4.1M

Select item 114305153.

Connexin Expression Is Altered in the Eye Development of Yotari Mice: A Preliminary Study

Ljubica Skelin, Anita Racetin, Nela Kelam, Marin Ogorevc, Ljubo Znaor, Mirna Saraga-Babić, Natalija Filipović, Yu Katsuyama, Zenon Pogorelić, Katarina Vukojević

Biomolecules. 2024 Sep; 14(9): 1174. Published online 2024 Sep 19. doi: 10.3390/biom14091174

PMCID:: PMC11430515

Abstract Article PDF–31M

Select item 111133214.

Cardiac outflow tract development relies on the complex function of Sox4 and Sox11 in multiple cell types

Mandy H. Paul, Richard P. Harvey, Michael Wegner, Elisabeth Sock

Cell Mol Life Sci. 2014 Aug; 71(15): 2931–2945. Published online 2013 Dec 6. doi: 10.1007/s00018-013-1523-x

PMCID:: PMC11113321

Abstract Article PDF–3.3M

Select item 110720925.

Lineage-tracing hematopoietic stem cell origins in vivo to efficiently make human HLF+ HOXA+ hematopoietic progenitors from pluripotent stem cells

Jonas L. Fowler, Sherry Li Zheng, Alana Nguyen, Angela Chen, Xiaochen Xiong, Timothy Chai, Julie Y. Chen, Daiki Karigane, Allison M. Banuelos, Kouta Niizuma, Kensuke Kayamori, Toshinobu Nishimura, M. Kyle Cromer, David Gonzalez-Perez, Charlotte Mason, Daniel Dan Liu, Leyla Yilmaz, Lucile Miquerol, Matthew H. Porteus, Vincent C. Luca, Ravindra Majeti, Hiromitsu Nakauchi, Kristy Red-Horse, Irving L. Weissman, Lay Teng Ang, Kyle M. Loh

Dev Cell. 2024 May 6; 59(9): 1110–1131.e22. doi: 10.1016/j.devcel.2024.03.003

PMCID:: PMC11072092

Abstract Article PDF–8.3M

Select item 109484856.

Reprogramming of the developing heart by Hif1a-deficient sympathetic system and maternal diabetes exposure

Hana Kolesova, Petra Hrabalova, Romana Bohuslavova, Pavel Abaffy, Valeria Fabriciova, David Sedmera, Gabriela Pavlinkova

Front Endocrinol (Lausanne) 2024; 15: 1344074. Published online 2024 Mar 5. doi: 10.3389/fendo.2024.1344074

PMCID:: PMC10948485

Abstract Article PDF–7.6M

Select item 109054237.

An Anterior Second Heart Field Enhancer Regulates the Gene Regulatory Network of the Cardiac Outflow Tract

Naoko Yamaguchi, Ernest W. Chang, Ziyan Lin, Akshay Shekhar, Lei Bu, Alireza Khodadadi-Jamayran, Aristotelis Tsirigos, Yiyun Cen, Colin K. L. Phoon, Ivan P. Moskowitz, David S. Park

Circulation. Author manuscript; available in PMC 2024 Nov 21.

Published in final edited form as: Circulation. 2023 Nov 21; 148(21): 1705–1722. Published online 2023 Sep 29. doi: 10.1161/CIRCULATIONAHA.123.065700

PMCID:: PMC10905423

Abstract Article PDF–3.5M

Select item 108953558.

Capillary oxygen regulates demand–supply coupling by triggering connexin40-mediated conduction: Rethinking the metabolic hypothesis

Paulina M. Kowalewska, Stephanie L. Milkovich, Daniel Goldman, Shaun L. Sandow, Christopher G. Ellis, Donald G. Welsh

Proc Natl Acad Sci U S A. 2024 Feb 20; 121(8): e2303119121. Published online 2024 Feb 13. doi: 10.1073/pnas.2303119121

PMCID:: PMC10895355

Abstract Article PDF–5.9M

Select item 107922479.

Atrial natriuretic peptide signaling co-regulates lipid metabolism and ventricular conduction system gene expression in the embryonic heart

Abhishek Mishra, Mahtab Tavasoli, Stanislav Sokolenko, Christopher R. McMaster, Kishore B.S. Pasumarthi

iScience. 2024 Jan 19; 27(1): 108748. Published online 2023 Dec 14. doi: 10.1016/j.isci.2023.108748

PMCID:: PMC10792247

Abstract Article PDF–9.2M

Select item 1075188410.

Lack of connexin 40 decreases the calcium sensitivity of renin secreting juxtaglomerular cells

Dominik Steppan, Lisa Geis, Lin Pan, Kenneth Gross, Charlotte Wagner, Armin Kurtz

Pflugers Arch. Author manuscript; available in PMC 2023 Dec 27.

Published in final edited form as: Pflugers Arch. 2018 Jun; 470(6): 969–978. Published online 2018 Feb 9. doi: 10.1007/s00424-018-2119-y

PMCID:: PMC10751884

Abstract Article PDF–2.1M

Select item 1068461711.

Dbh⁺ catecholaminergic cardiomyocytes contribute to the structure and function of the cardiac conduction system in murine heart

Tianyi Sun, Alexander Grassam-Rowe, Zhaoli Pu, Yangpeng Li, Huiying Ren, Yanru An, Xinyu Guo, Wei Hu, Ying Liu, Yuqing Zheng, Zhu Liu, Kun Kou, Xianhong Ou, Tangting Chen, Xuehui Fan, Yangyang Liu, Shu Tu, Yu He, Yue Ren, Ao Chen, Zhouchun Shang, Zhidao Xia, Lucile Miquerol, Nicola Smart, Henggui Zhang, Xiaoqiu Tan, Weinian Shou, Ming Lei

Nat Commun. 2023; 14: 7801. Published online 2023 Nov 28. doi: 10.1038/s41467-023-42658-9

PMCID:: PMC10684617

Abstract Article PDF–23M

Select item 1063150912.

Nrg1 Regulates Cardiomyocyte Migration and Cell Cycle in Ventricular Development

Joaquim Grego-Bessa, Paula Gómez-Apiñaniz, Belén Prados, Manuel José Gómez, Donal MacGrogan, José Luis de la Pompa

Circ Res. 2023 Nov 10; 133(11): 927–943. Published online 2023 Oct 17. doi: 10.1161/CIRCRESAHA.123.323321

PMCID:: PMC10631509

Abstract Article PDF–9.0M

Select item 1006637913.

Endothelial deletion of PTBP1 disrupts ventricular chamber development

Hongyu Liu, Ran Duan, Xiaoyu He, Jincu Qi, Tianming Xing, Yahan Wu, Liping Zhou, Lingling Wang, Yujing Shao, Fulei Zhang, Huixing Zhou, Xingdong Gu, Bowen Lin, Yuanyuan Liu, Yan Wang, Yi Liu, Li Li, Dandan Liang, Yi-Han Chen

Nat Commun. 2023; 14: 1796. Published online 2023 Mar 31. doi: 10.1038/s41467-023-37409-9

PMCID:: PMC10066379

Abstract Article PDF–7.8M

Select item 1002316114.

The long noncoding RNA Charme supervises cardiomyocyte maturation by controlling cell differentiation programs in the developing heart

Valeria Taliani, Giulia Buonaiuto, Fabio Desideri, Adriano Setti, Tiziana Santini, Silvia Galfrè, Leonardo Schirone, Davide Mariani, Giacomo Frati, Valentina Valenti, Sebastiano Sciarretta, Emerald Perlas, Carmine Nicoletti, Antonio Musarò, Monica Ballarino

eLife. 2023; 12: e81360. Published online 2023 Mar 6. doi: 10.7554/eLife.81360

PMCID:: PMC10023161

Abstract Article PDF–4.8M

Select item 968701815.

CXCL12 defines lung endothelial heterogeneity and promotes distal vascular growth

Prashant Chandrasekaran, Nicholas M. Negretti, Aravind Sivakumar, Derek C. Liberti, Hongbo Wen, Maureen Peers de Nieuwburgh, Joanna Y. Wang, Nigel S. Michki, Fatima N. Chaudhry, Sukhmani Kaur, MinQi Lu, Annabelle Jin, Jarod A. Zepp, Lisa R. Young, Jennifer M. S. Sucre, David B. Frank

Development. 2022 Nov 1; 149(21): dev200909. Published online 2022 Oct 31. doi: 10.1242/dev.200909

PMCID:: PMC9687018

Abstract Article

Select item 956689916.

In vivo visualization and molecular targeting of the cardiac conduction system

William R. Goodyer, Benjamin M. Beyersdorf, Lauren Duan, Nynke S. van den Berg, Sruthi Mantri, Francisco X. Galdos, Nazan Puluca, Jan W. Buikema, Soah Lee, Darren Salmi, Elise R. Robinson, Stephan Rogalla, Dillon P. Cogan, Chaitan Khosla, Eben L. Rosenthal, Sean M. Wu

J Clin Invest. 2022 Oct 17; 132(20): e156955. Published online 2022 Oct 17. doi: 10.1172/JCI156955

PMCID:: PMC9566899

Abstract Article PDF–9.4M

Select item 953612517.

Heterogeneity and developmental dynamics of LYVE-1 perivascular macrophages distribution in the mouse brain

Marie Karam, Hadrien Janbon, Guy Malkinson, Isabelle Brunet

J Cereb Blood Flow Metab. 2022 Oct; 42(10): 1797–1812. Published online 2022 Jun 24. doi: 10.1177/0271678X221101643

PMCID:: PMC9536125

Abstract Article PDF–64M

Select item 953153518.

NOTCH maintains developmental cardiac gene network through WNT5A

Yidong Wang, Pengfei Lu, Bingruo Wu, Bernice E. Morrow, Bin Zhou

J Mol Cell Cardiol. Author manuscript; available in PMC 2022 Oct 4.

Published in final edited form as: J Mol Cell Cardiol. 2018 Dec; 125: 98–105. Published online 2018 Oct 19. doi: 10.1016/j.yjmcc.2018.10.014

PMCID:: PMC9531535

Abstract Article PDF–1.3M

Select item 950626919.

Connexin Lateralization Contributes to Male Susceptibility to Atrial Fibrillation

Simon Thibault, Anh-Tuan Ton, François Huynh, Céline Fiset

Int J Mol Sci. 2022 Sep; 23(18): 10696. Published online 2022 Sep 14. doi: 10.3390/ijms231810696

PMCID:: PMC9506269

Abstract Article PDF–4.0M

Select item 900773720.

Compartmentalized metabolism supports midgestation mammalian development

Ashley Solmonson, Brandon Faubert, Wen Gu, Aparna Rao, Mitzy A. Cowdin, Ivan Menendez-Montes, Sherwin Kelekar, Thomas J. Rogers, Chunxiao Pan, Gerardo Guevara, Amy Tarangelo, Lauren G. Zacharias, Misty S. Martin-Sandoval, Duyen Do, Panayotis Pachnis, Dennis Dumesnil, Thomas P. Mathews, Alpaslan Tasdogan, An Pham, Ling Cai, Zhiyu Zhao, Min Ni, Ondine Cleaver, Hesham A. Sadek, Sean J. Morrison, Ralph J. DeBerardinis

Nature. 2022; 604(7905): 349–353. Published online 2022 Apr 6. doi: 10.1038/s41586-022-04557-9

PMCID:: PMC9007737

Abstract Article PDF–6.0M

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