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Items: 1 to 20 of 69

1.
A fluorescent perilipin 2 knock-in mouse model reveals a high abundance of lipid droplets in the developing and adult brain
Sofia Madsen, Ana C. Delgado, Christelle Cadilhac, Vanille Maillard, Fabrice Battiston, Carla Marie Igelbüscher, Simon De Neck, Elia Magrinelli, Denis Jabaudon, Ludovic Telley, Fiona Doetsch, Marlen Knobloch
Nat Commun. 2024; 15: 5489. Published online 2024 Jun 28. doi: 10.1038/s41467-024-49449-w
PMCID:
PMC11213871
AbstractArticlePDF–7.1M
2.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
3.
MAGL protects against renal fibrosis through inhibiting tubular cell lipotoxicity
Shan Zhou, Xian Ling, Jielin Zhu, Ye Liang, Qijian Feng, Chao Xie, Jiemei Li, Qiyan Chen, Shuangqin Chen, Jinhua Miao, Mengyao Zhang, Zhiru Li, Weiwei Shen, Xiaolong Li, Qinyu Wu, Xiaoxu Wang, Ruiyuan Liu, Cheng Wang, Fan Fan Hou, Yaozhong Kong, Youhua Liu, Lili Zhou
Theranostics. 2024; 14(4): 1583–1601. Published online 2024 Feb 4. doi: 10.7150/thno.92848
PMCID:
PMC10879875
AbstractArticlePDF–18M
4.
Identification of new ciliary signaling pathways in the brain and insights into neurological disorders
Abdelhalim Loukil, Emma Ebright, Akiyoshi Uezu, Yudong Gao, Scott H Soderling, Sarah C. Goetz
Version 1. bioRxiv. Preprint. 2023 Dec 21. doi: 10.1101/2023.12.20.572700
PMCID:
PMC10769350
AbstractArticlePDF–11M
5.
Monoacylglycerol lipase reprograms hepatocytes and macrophages to promote liver regeneration
Manon Allaire, Rola Al Sayegh, Morgane Mabire, Adel Hammoutene, Matthieu Siebert, Charles Caër, Mathilde Cadoux, JingHong Wan, Aida Habib, Maude Le Gall, Pierre de la Grange, Hervé Guillou, Catherine Postic, Valérie Paradis, Sophie Lotersztajn, Hélène Gilgenkrantz
JHEP Rep. 2023 Aug; 5(8): 100794. Published online 2023 May 16. doi: 10.1016/j.jhepr.2023.100794
Correction in:
JHEP Rep. 2024 Jun; 6(6): 101096.
PMCID:
PMC10382928
AbstractArticlePDF–2.5M
6.
MAGL regulates synovial macrophage polarization vis inhibition of mitophagy in osteoarthritic pain
Chengyong Gu, Mo Chen, Xueyan Li, Dechun Geng, Chen Wang
Mol Med Rep. 2023 Jun; 27(6): 117. Published online 2023 May 2. doi: 10.3892/mmr.2023.13004
PMCID:
PMC10172810
AbstractArticlePDF–1.8M
7.
Monoglyceride Lipase Deficiency Is Associated with Altered Thrombogenesis in Mice
Madeleine Goeritzer, Katharina B. Kuentzel, Sarah Beck, Melanie Korbelius, Silvia Rainer, Ivan Bradić, Dagmar Kolb, Marion Mussbacher, Waltraud C. Schrottmaier, Alice Assinger, Axel Schlagenhauf, René Rost, Benjamin Gottschalk, Thomas O. Eichmann, Thomas Züllig, Wolfgang F. Graier, Nemanja Vujić, Dagmar Kratky
Int J Mol Sci. 2023 Feb; 24(4): 3116. Published online 2023 Feb 4. doi: 10.3390/ijms24043116
PMCID:
PMC9958834
AbstractArticlePDF–5.1M
8.
The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3
Laura Sánchez-Bellver, Andrea Férriz-Gordillo, Marc Carrillo-Pz, Laura Rabanal, Francesc R. Garcia-Gonzalo, Gemma Marfany
Int J Mol Sci. 2022 Oct; 23(20): 12527. Published online 2022 Oct 19. doi: 10.3390/ijms232012527
PMCID:
PMC9603860
AbstractArticlePDF–3.4M
9.
The Effects of Maternal Intake of EPA and DHA Enriched Diet During Pregnancy and Lactation on Offspring’s Muscle Development and Energy Homeostasis
Saeed Ghnaimawi, Shilei Zhang, Jamie I. Baum, Yan Huang
Front Physiol. 2022; 13: 881624. Published online 2022 Jun 6. doi: 10.3389/fphys.2022.881624
PMCID:
PMC9207413
AbstractArticlePDF–6.0M
10.
In situ Identification of Cellular Drug Targets in Mammalian Tissue
Zhengyuan Pang, Michael A. Schafroth, Daisuke Ogasawara, Yu Wang, Victoria Nudell, Neeraj Lal, Dong Yang, Kristina Wang, Dylan M Herbst, Jacquelyn Ha, Carlos Guijas, Jacqueline L Blankman, Benjamin F. Cravatt, Li Ye
Cell. Author manuscript; available in PMC 2023 May 12.
Published in final edited form as: Cell. 2022 May 12; 185(10): 1793–1805.e17. Published online 2022 Apr 27. doi: 10.1016/j.cell.2022.03.040
PMCID:
PMC9106931
AbstractArticlePDF–3.0M
11.
The Novel Monoacylglycerol Lipase Inhibitor MJN110 Suppresses Neuroinflammation, Normalizes Synaptic Composition and Improves Behavioral Performance in the Repetitive Traumatic Brain Injury Mouse Model
Prabhuanand Selvaraj, Mikiei Tanaka, Jie Wen, Yumin Zhang
Cells. 2021 Dec; 10(12): 3454. Published online 2021 Dec 8. doi: 10.3390/cells10123454
PMCID:
PMC8700188
AbstractArticlePDF–4.1M
12.
Monoacylglycerol lipase deficiency in the tumor microenvironment slows tumor growth in non-small cell lung cancer
Melanie Kienzl, Carina Hasenoehrl, Kathrin Maitz, Arailym Sarsembayeva, Ulrike Taschler, Paulina Valadez-Cosmes, Oliver Kindler, Dusica Ristic, Sofia Raftopoulou, Ana Santiso, Thomas Bärnthaler, Luka Brcic, Lisa Hahnefeld, Robert Gurke, Dominique Thomas, Gerd Geisslinger, Julia Kargl, Rudolf Schicho
Oncoimmunology. 2021; 10(1): 1965319. Published online 2021 Sep 11. doi: 10.1080/2162402X.2021.1965319
PMCID:
PMC8437460
AbstractArticlePDF–3.0M
13.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
14.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
15.
Absence of Adiponutrin (PNPLA3) and Monoacylglycerol Lipase Synergistically Increases Weight Gain and Aggravates Steatohepatitis in Mice
Matteo Tardelli, Francesca V. Bruschi, Claudia D. Fuchs, Thierry Claudel, Nicole Auer, Victoria Kunczer, Onne A. H. O. Ronda, Henkjan J. Verkade, Tatjana Stojakovic, Hubert Scharnagl, Michael Trauner
Int J Mol Sci. 2021 Feb; 22(4): 2126. Published online 2021 Feb 20. doi: 10.3390/ijms22042126
PMCID:
PMC7924608
AbstractArticlePDF–3.4M
16.
Mgll Knockout Mouse Resistance to Diet-Induced Dysmetabolism Is Associated with Altered Gut Microbiota
Niokhor Dione, Sébastien Lacroix, Ulrike Taschler, Thomas Deschênes, Armita Abolghasemi, Nadine Leblanc, Vincenzo Di Marzo, Cristoforo Silvestri
Cells. 2020 Dec; 9(12): 2705. Published online 2020 Dec 17. doi: 10.3390/cells9122705
PMCID:
PMC7765900
AbstractArticlePDF–2.0M
17.
Endocannabinoid signaling regulates the reinforcing and psychostimulant effects of ketamine in mice
Wei Xu, Hongchun Li, Liang Wang, Jiamei Zhang, Chunqi Liu, Xuemei Wan, Xiaochong Liu, Yiming Hu, Qiyao Fang, Yuanyuan Xiao, Qian Bu, Hongbo Wang, Jingwei Tian, Yinglan Zhao, Xiaobo Cen
Nat Commun. 2020; 11: 5962. Published online 2020 Nov 24. doi: 10.1038/s41467-020-19780-z
PMCID:
PMC7686380
AbstractArticlePDF–3.4M
18.
Endocannabinoids Inhibit the Induction of Virulence in Enteric Pathogens
Melissa Ellermann, Alline R. Pacheco, Angel G. Jimenez, Regan Russell, Santiago Cuesta, Aman Kumar, Wenhan Zhu, Gonç alo Vale, Sarah A. Martin, Prithvi Raj, Jeffrey McDonald, Sebastian E. Winter, Vanessa Sperandio
Cell. Author manuscript; available in PMC 2021 Oct 29.
Published in final edited form as: Cell. 2020 Oct 29; 183(3): 650–665.e15. Published online 2020 Oct 7. doi: 10.1016/j.cell.2020.09.022
PMCID:
PMC7606741
AbstractArticlePDF–2.8M
19.
Inhibition of Monoacylglycerol Lipase Reduces Nicotine Reward in the Conditioned Place Preference Test in Male Mice
Pretal P. Muldoon, Lois S. Akinola, Joel E. Schlosburg, Aron H. Lichtman, Laura J. Sim-Selley, Anu Mahadevan, Benjamin F. Cravatt, M. Imad Damaj
Neuropharmacology. Author manuscript; available in PMC 2021 Oct 1.
Published in final edited form as: Neuropharmacology. 2020 Oct 1; 176: 108170. Published online 2020 May 30. doi: 10.1016/j.neuropharm.2020.108170
PMCID:
PMC7529882
AbstractArticlePDF–839K
20.
Monoglyceride lipase mediates tumor-suppressive effects by promoting degradation of X-linked inhibitor of apoptosis protein
Renyan Liu, Xin Wang, Christopher Curtiss, M. Saeed Sheikh, Ying Huang
Cell Death Differ. 2020 Oct; 27(10): 2888–2903. Published online 2020 May 6. doi: 10.1038/s41418-020-0549-5
PMCID:
PMC7494902
AbstractArticlePDF–4.3M

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