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Items: 1 to 20 of 41

1.
MBNL splicing factors regulate the microtranscriptome of skeletal muscles
Agnieszka Piasecka, Michał W Szcześniak, Michał Sekrecki, Arkadiusz Kajdasz, Łukasz J Sznajder, Anna Baud, Krzysztof Sobczak
Nucleic Acids Res. 2024 Oct 28; 52(19): 12055–12073. Published online 2024 Sep 11. doi: 10.1093/nar/gkae774
PMCID:
PMC11514471
AbstractArticlePDF–2.4M
2.
Cypher/ZASP drives cardiomyocyte maturation via actin-mediated MRTFA-SRF signalling
Jialan Lyu, Zhicheng Pan, Ruobing Li, Hailong Yu, Yuesheng Zhang, Dongfei Wang, Xiang Yin, Yan He, Liding Zhao, Siyuan Chen, Shan Zhang, Hongqiang Cheng, Xiaogang Guo
Theranostics. 2024; 14(11): 4462–4480. Published online 2024 Jul 22. doi: 10.7150/thno.98734
PMCID:
PMC11303069
AbstractArticlePDF–8.2M
3.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
4.
Expression of LIM domain-binding 3 (LDB3), a striated muscle Z-band alternatively spliced PDZ-motif protein in the nervous system
Yotam Blech-Hermoni, Kalpana Subedi, Maya Silver, Leah Jensen, Stephen Coscia, Malcolm M. Kates, Yongmei Zhao, Castle Raley, Nancy Edwards, Bao Tran, Abhik Ray-Chaudhary, Pankaj Pathak, Ami Mankodi
Sci Rep. 2023; 13: 270. Published online 2023 Jan 6. doi: 10.1038/s41598-023-27531-5
PMCID:
PMC9822979
AbstractArticlePDF–8.7M
5.
Phosphoproteomic Analysis Reveals Downstream PKA Effectors of AKAP Cypher/ZASP in the Pathogenesis of Dilated Cardiomyopathy
Jialan Lv, Zhicheng Pan, Jian Chen, Rui Xu, Dongfei Wang, Jiaqi Huang, Yang Dong, Jing Jiang, Xiang Yin, Hongqiang Cheng, Xiaogang Guo
Front Cardiovasc Med. 2021; 8: 753072. Published online 2021 Dec 13. doi: 10.3389/fcvm.2021.753072
PMCID:
PMC8710605
AbstractArticlePDF–5.2M
6.
Myopathy associated LDB3 mutation causes Z-disc disassembly and protein aggregation through PKCα and TSC2-mTOR downregulation
Pankaj Pathak, Yotam Blech-Hermoni, Kalpana Subedi, Jessica Mpamugo, Charissa Obeng-Nyarko, Rachel Ohman, Ilda Molloy, Malcolm Kates, Jessica Hale, Stacey Stauffer, Shyam K. Sharan, Ami Mankodi
Commun Biol. 2021; 4: 355. Published online 2021 Mar 19. doi: 10.1038/s42003-021-01864-1
PMCID:
PMC7979776
AbstractArticlePDF–5.3M
7.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
8.
Downregulation of Cypher induces apoptosis in cardiomyocytes via Akt/p38 MAPK signaling pathway
Tianming Xuan, Dongfei Wang, Jialan Lv, Zhicheng Pan, Juan Fang, Yin Xiang, Hongqiang Cheng, Xingxiang Wang, Xiaogang Guo
Int J Med Sci. 2020; 17(15): 2328–2337. Published online 2020 Aug 27. doi: 10.7150/ijms.48872
PMCID:
PMC7484636
AbstractArticlePDF–1.2M
9.
The AKAP Cypher/Zasp contributes to β-adrenergic/PKA stimulation of cardiac CaV1.2 calcium channels
Haijie Yu, Can Yuan, Ruth E. Westenbroek, William A. Catterall
J Gen Physiol. 2018 Jun 4; 150(6): 883–889. doi: 10.1085/jgp.201711818
PMCID:
PMC5987873
AbstractArticlePDF–1.2M
10.
Chemical cross-linking mass spectrometry analysis of protein conformations and supercomplexes in heart tissue
Juan D. Chavez, Chi Fung Lee, Arianne Caudal, Andrew Keller, Rong Tian, James E. Bruce
Cell Syst. Author manuscript; available in PMC 2019 Jan 24.
Published in final edited form as: Cell Syst. 2018 Jan 24; 6(1): 136–141.e5. Published online 2017 Nov 29. doi: 10.1016/j.cels.2017.10.017
PMCID:
PMC5799023
AbstractArticlePDF–730K
11.
HSPB7 is indispensable for heart development by modulating actin filament assembly
Tongbin Wu, Yongxin Mu, Julius Bogomolovas, Xi Fang, Jennifer Veevers, Roberta B. Nowak, Christopher T. Pappas, Carol C. Gregorio, Sylvia M. Evans, Velia M. Fowler, Ju Chen
Proc Natl Acad Sci U S A. 2017 Nov 7; 114(45): 11956–11961. Published online 2017 Oct 23. doi: 10.1073/pnas.1713763114
PMCID:
PMC5692592
AbstractArticlePDF–1.1M
12.
Extensive alternative splicing transitions during postnatal skeletal muscle development are required for calcium handling functions
Amy E Brinegar, Zheng Xia, James Anthony Loehr, Wei Li, George Gerald Rodney, Thomas A Cooper
eLife. 2017; 6: e27192. Published online 2017 Aug 11. doi: 10.7554/eLife.27192
PMCID:
PMC5577920
AbstractArticlePDF–3.6M
13.
Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function
Tingting Zhang, Wei Du, Andrew F. Wilson, Satoshi H. Namekawa, Paul R. Andreassen, Amom Ruhikanta Meetei, Qishen Pang
Sci Rep. 2017; 7: 45626. Published online 2017 Apr 5. doi: 10.1038/srep45626
PMCID:
PMC5381226
AbstractArticlePDF–1.4M
14.
Pericytes of multiple organs do not behave as mesenchymal stem cells in vivo
Nuno Guimarães-Camboa, Paola Cattaneo, Yunfu Sun, Thomas Moore-Morris, Yusu Gu, Nancy D. Dalton, Edward Rockenstein, Eliezer Masliah, Kirk L. Peterson, William B. Stallcup, Ju Chen, Sylvia M. Evans
Cell Stem Cell. Author manuscript; available in PMC 2018 Mar 2.
Published in final edited form as: Cell Stem Cell. 2017 Mar 2; 20(3): 345–359.e5. Published online 2017 Jan 19. doi: 10.1016/j.stem.2016.12.006
PMCID:
PMC5337131
AbstractArticlePDF–1.3M
15.
Cypher and Enigma Homolog Protein Are Essential for Cardiac Development and Embryonic Survival
Yongxin Mu, Ran Jing, Angela K Peter, Stephan Lange, Lizhu Lin, Jianlin Zhang, Kunfu Ouyang, Xi Fang, Jennifer Veevers, Xinmin Zhou, Sylvia M Evans, Hongqiang Cheng, Ju Chen
J Am Heart Assoc. 2015 May; 4(5): e001950. Published online 2015 May 5. doi: 10.1161/JAHA.115.001950
Correction in:
J Am Heart Assoc. 2015 Jul; 4(7): e001930.
PMCID:
PMC4599425
AbstractArticlePDF–1.4M
16.
Nebulette knockout mice have normal cardiac function, but show Z-line widening and up-regulation of cardiac stress markers
Giuseppina Mastrototaro, Xingqun Liang, Xiaodong Li, Pierluigi Carullo, Nicoletta Piroddi, Chiara Tesi, Yusu Gu, Nancy D. Dalton, Kirk L. Peterson, Corrado Poggesi, Farah Sheikh, Ju Chen, Marie-Louise Bang
Cardiovasc Res. 2015 Jul 15; 107(2): 216–225. Published online 2015 May 18. doi: 10.1093/cvr/cvv156
PMCID:
PMC4565986
AbstractArticle
17.
Knockout of SRC-1 and SRC-3 in Mice Decreases Cardiomyocyte Proliferation and Causes a Noncompaction Cardiomyopathy Phenotype
Xian Chen, Li Qin, Zhaoliang Liu, Lan Liao, James F. Martin, Jianming Xu
Int J Biol Sci. 2015; 11(9): 1056–1072. Published online 2015 Jul 15. doi: 10.7150/ijbs.12408
PMCID:
PMC4515817
AbstractArticlePDF–2.5M
18.
Gene Expression by Mouse Inner Ear Hair Cells during Development
Déborah I. Scheffer, Jun Shen, David P. Corey, Zheng-Yi Chen
J Neurosci. 2015 Apr 22; 35(16): 6366–6380. doi: 10.1523/JNEUROSCI.5126-14.2015
PMCID:
PMC4405555
AbstractArticlePDF–4.2M
19.
Z-disc-associated, Alternatively Spliced, PDZ Motif-containing Protein (ZASP) Mutations in the Actin-binding Domain Cause Disruption of Skeletal Muscle Actin Filaments in Myofibrillar Myopathy
Xiaoyan Lin, Janelle Ruiz, Ilda Bajraktari, Rachel Ohman, Soojay Banerjee, Katherine Gribble, Joshua D. Kaufman, Paul T. Wingfield, Robert C. Griggs, Kenneth H. Fischbeck, Ami Mankodi
J Biol Chem. 2014 May 9; 289(19): 13615–13626. Published online 2014 Mar 25. doi: 10.1074/jbc.M114.550418
PMCID:
PMC4036366
AbstractArticlePDF–5.2M
20.
Cypher/ZASP Is a Novel A-kinase Anchoring Protein
Changsong Lin, Xiaogang Guo, Stephan Lange, Jie Liu, Kunfu Ouyang, Xiang Yin, Liujun Jiang, Yibo Cai, Yongxin Mu, Farah Sheikh, Sheng Ye, Ju Chen, Yuehai Ke, Hongqiang Cheng
J Biol Chem. 2013 Oct 11; 288(41): 29403–29413. Published online 2013 Aug 31. doi: 10.1074/jbc.M113.470708
PMCID:
PMC3795241
AbstractArticlePDF–3.4M

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