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Items: 1 to 20 of 47

1.
Differential CpG methylation at Nnat in the early establishment of beta cell heterogeneity
Vanessa Yu, Fiona Yong, Angellica Marta, Sanjay Khadayate, Adrien Osakwe, Supriyo Bhattacharya, Sneha S. Varghese, Pauline Chabosseau, Sayed M. Tabibi, Keran Chen, Eleni Georgiadou, Nazia Parveen, Mara Suleiman, Zoe Stamoulis, Lorella Marselli, Carmela De Luca, Marta Tesi, Giada Ostinelli, Luis Delgadillo-Silva, Xiwei Wu, Yuki Hatanaka, Alex Montoya, James Elliott, Bhavik Patel, Nikita Demchenko, Chad Whilding, Petra Hajkova, Pavel Shliaha, Holger Kramer, Yusuf Ali, Piero Marchetti, Robert Sladek, Sangeeta Dhawan, Dominic J. Withers, Guy A. Rutter, Steven J. Millership
Diabetologia. 2024; 67(6): 1079–1094. Published online 2024 Mar 21. doi: 10.1007/s00125-024-06123-6
PMCID:
PMC11058053
AbstractArticlePDF–7.7M
2.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
3.
NEUROD1 reinforces endocrine cell fate acquisition in pancreatic development
Romana Bohuslavova, Valeria Fabriciova, Ondrej Smolik, Laura Lebrón-Mora, Pavel Abaffy, Sarka Benesova, Daniel Zucha, Lukas Valihrach, Zuzana Berkova, Frantisek Saudek, Gabriela Pavlinkova
Nat Commun. 2023; 14: 5554. Published online 2023 Sep 9. doi: 10.1038/s41467-023-41306-6
PMCID:
PMC10492842
AbstractArticlePDF–15M
4.
Independent phenotypic plasticity axes define distinct obesity sub-types
Chih-Hsiang Yang, Luca Fagnocchi, Stefanos Apostle, Vanessa Wegert, Salvador Casaní-Galdón, Kathrin Landgraf, Ilaria Panzeri, Erez Dror, Steffen Heyne, Till Wörpel, Darrell P. Chandler, Di Lu, Tao Yang, Elizabeth Gibbons, Rita Guerreiro, Jose Bras, Martin Thomasen, Louise G. Grunnet, Allan A. Vaag, Linn Gillberg, Elin Grundberg, Ana Conesa, Antje Körner, PERMUTE, J. Andrew Pospisilik
Nat Metab. 2022; 4(9): 1150–1165. Published online 2022 Sep 12. doi: 10.1038/s42255-022-00629-2
PMCID:
PMC9499872
AbstractArticlePDF–21M
5.
Spatiotemporal single-cell regulatory atlas reveals neural crest lineage diversification and cellular function during tooth morphogenesis
Junjun Jing, Jifan Feng, Yuan Yuan, Tingwei Guo, Jie Lei, Fei Pei, Thach-Vu Ho, Yang Chai
Nat Commun. 2022; 13: 4803. Published online 2022 Aug 16. doi: 10.1038/s41467-022-32490-y
PMCID:
PMC9381504
AbstractArticlePDF–6.6M
6.
Murine neuronatin deficiency is associated with a hypervariable food intake and bimodal obesity
Irene Cimino, Debra Rimmington, Y. C. Loraine Tung, Katherine Lawler, Pierre Larraufie, Richard G. Kay, Samuel Virtue, Brian Y. H. Lam, Luca Fagnocchi, Marcella K. L. Ma, Vladimir Saudek, Ilona Zvetkova, Antonio Vidal-Puig, Giles S. H. Yeo, I. Sadaf Farooqi, J. Andrew Pospisilik, Fiona M. Gribble, Frank Reimann, Stephen O’Rahilly, Anthony P. Coll
Sci Rep. 2021; 11: 17571. Published online 2021 Sep 2. doi: 10.1038/s41598-021-96278-8
PMCID:
PMC8413370
AbstractArticlePDF–1.5M
7.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
8.
ZFP57 dictates allelic expression switch of target imprinted genes
Weijun Jiang, Jiajia Shi, Jingjie Zhao, Qiu Wang, Dan Cong, Fenghua Chen, Yu Zhang, Yuhan Liu, Junzheng Zhao, Qian Chen, Linhao Gu, Wenjia Zhou, Chenhang Wang, Zhaoyuan Fang, Shuhui Geng, Wei Xie, Luo-Nan Chen, Yang Yang, Yun Bai, Haodong Lin, Xiajun Li
Proc Natl Acad Sci U S A. 2021 Feb 2; 118(5): e2005377118. Published online 2021 Jan 26. doi: 10.1073/pnas.2005377118
PMCID:
PMC7865185
AbstractArticlePDF–1.8M
9.
Down-Regulation of miRNA-708 Promotes Aberrant Calcium Signaling by Targeting Neuronatin in a Mouse Model of Angelman Syndrome
Naman Vatsa, Vipendra Kumar, Brijesh Kumar Singh, Shashi Shekhar Kumar, Ankit Sharma, Nihar Ranjan Jana
Front Mol Neurosci. 2019; 12: 35. Published online 2019 Feb 13. doi: 10.3389/fnmol.2019.00035
PMCID:
PMC6381399
AbstractArticlePDF–4.0M
10.
Neuronatin deletion causes postnatal growth restriction and adult obesity in 129S2/Sv mice
Steven J. Millership, Simon J. Tunster, Mathew Van de Pette, Agharul I. Choudhury, Elaine E. Irvine, Mark Christian, Amanda G. Fisher, Rosalind M. John, James Scott, Dominic J. Withers
Mol Metab. 2018 Dec; 18: 97–106. Published online 2018 Sep 15. doi: 10.1016/j.molmet.2018.09.001
PMCID:
PMC6308027
AbstractArticlePDF–1.4M
11.
Neuronatin regulates pancreatic β cell insulin content and secretion
Steven J. Millership, Gabriela Da Silva Xavier, Agharul I. Choudhury, Sergio Bertazzo, Pauline Chabosseau, Silvia M.A. Pedroni, Elaine E. Irvine, Alex Montoya, Peter Faull, William R. Taylor, Julie Kerr-Conte, Francois Pattou, Jorge Ferrer, Mark Christian, Rosalind M. John, Mathieu Latreille, Ming Liu, Guy A. Rutter, James Scott, Dominic J. Withers
J Clin Invest. 2018 Aug 1; 128(8): 3369–3381. Published online 2018 Jul 9. doi: 10.1172/JCI120115
PMCID:
PMC6063487
AbstractArticlePDF–3.0M
12.
Developmental diversification of cortical inhibitory interneurons
Christian Mayer, Christoph Hafemeister, Rachel C. Bandler, Robert Machold, Renata Batista Brito, Xavier Jaglin, Kathryn Allaway, Andrew Butler, Gord Fishell, Rahul Satija
Nature. Author manuscript; available in PMC 2018 Sep 5.
Published in final edited form as: Nature. 2018 Mar 22; 555(7697): 457–462. Published online 2018 Mar 5. doi: 10.1038/nature25999
PMCID:
PMC6052457
AbstractArticlePDF–2.3M
13.
Cellular heterogeneity in the ureteric progenitor niche and distinct profiles of branching morphogenesis in organ development
Elisabeth A. Rutledge, Jean-Denis Benazet, Andrew P. McMahon
Development. 2017 Sep 1; 144(17): 3177–3188. doi: 10.1242/dev.149112
PMCID:
PMC5611955
AbstractArticle
14.
Tet proteins influence the balance between neuroectodermal and mesodermal fate choice by inhibiting Wnt signaling
Xiang Li, Xiaojing Yue, William A. Pastor, Lizhu Lin, Romain Georges, Lukas Chavez, Sylvia M. Evans, Anjana Rao
Proc Natl Acad Sci U S A. 2016 Dec 20; 113(51): E8267–E8276. Published online 2016 Dec 5. doi: 10.1073/pnas.1617802113
PMCID:
PMC5187696
AbstractArticlePDF–1.9M
15.
Sox4 Links Tumor Suppression to Accelerated Aging in Mice by Modulating Stem Cell Activation
Miguel Foronda, Paula Martínez, Stefan Schoeftner, Gonzalo Gómez-López, Ralph Schneider, Juana M. Flores, David G. Pisano, Maria A. Blasco
Cell Rep. Author manuscript; available in PMC 2016 Jun 13.
Published in final edited form as: Cell Rep. 2014 Jul 24; 8(2): 487–500. Published online 2014 Jul 17. doi: 10.1016/j.celrep.2014.06.031
PMCID:
PMC4905521
AbstractArticlePDF–2.8M
16.
βlinc1 encodes a long noncoding RNA that regulates islet β-cell formation and function
Luis Arnes, Ildem Akerman, Dina A. Balderes, Jorge Ferrer, Lori Sussel
Genes Dev. 2016 Mar 1; 30(5): 502–507. doi: 10.1101/gad.273821.115
PMCID:
PMC4782045
AbstractArticlePDF–490K
17.
Trim28 Haploinsufficiency Triggers Bi-stable Epigenetic Obesity
Kevin Dalgaard, Kathrin Landgraf, Steffen Heyne, Adelheid Lempradl, John Longinotto, Klaus Gossens, Marius Ruf, Michael Orthofer, Ruslan Strogantsev, Madhan Selvaraj, Tess Tsai-Hsiu Lu, Eduard Casas, Raffaele Teperino, M. Azim Surani, Ilona Zvetkova, Debra Rimmington, Y.C. Loraine Tung, Brian Lam, Rachel Larder, Giles S.H. Yeo, Stephen O’Rahilly, Tanya Vavouri, Emma Whitelaw, Josef M. Penninger, Thomas Jenuwein, Ching-Lung Cheung, Anne C. Ferguson-Smith, Anthony P. Coll, Antje Körner, J. Andrew Pospisilik
Cell. 2016 Jan 28; 164(3): 353–364. doi: 10.1016/j.cell.2015.12.025
PMCID:
PMC4735019
AbstractArticle
18.
The MAFB transcription factor impacts islet α-cell function in rodents and represents a unique signature of primate islet β-cells
Elizabeth Conrad, Chunhua Dai, Jason Spaeth, Min Guo, Holly A. Cyphert, David Scoville, Julie Carroll, Wei-Ming Yu, Lisa V. Goodrich, David M. Harlan, Kevin L. Grove, Charles T. Roberts, Jr., Alvin C. Powers, Guoqiang Gu, Roland Stein
Am J Physiol Endocrinol Metab. 2016 Jan 1; 310(1): E91–E102. Published online 2015 Nov 10. doi: 10.1152/ajpendo.00285.2015
PMCID:
PMC4675799
AbstractArticle
19.
A high resolution spatiotemporal atlas of gene expression of the developing mouse brain
Carol L. Thompson, Lydia Ng, Vilas Menon, Salvador Martinez, Chang-Kyu Lee, Katie Glattfelder, Susan M. Sunkin, Alex Henry, Christopher Lau, Chinh Dang, Raquel Garcia-Lopez, Almudena Martinez-Ferre, Ana Pombero, John L.R. Rubenstein, Wayne B. Wakeman, John Hohmann, Nick Dee, Andrew J. Sodt, Rob Young, Kimberly Smith, Thuc-Nghi Nguyen, Jolene Kidney, Leonard Kuan, Andreas Jeromin, Ajamete Kaykas, Jeremy Miller, Damon Page, Geri Orta, Amy Bernard, Zackery Riley, Simon Smith, Paul Wohnoutka, Mike Hawrylycz, Luis Puelles, Allan R. Jones
Neuron. Author manuscript; available in PMC 2015 Jul 16.
Published in final edited form as: Neuron. 2014 Jul 16; 83(2): 309–323. Published online 2014 Jun 19. doi: 10.1016/j.neuron.2014.05.033
PMCID:
PMC4319559
AbstractArticlePDF–3.0M
20.
Insm1 promotes endocrine cell differentiation by modulating the expression of a network of genes that includes Neurog3 and Ripply3
Anna B. Osipovich, Qiaoming Long, Elisabetta Manduchi, Rama Gangula, Susan B. Hipkens, Judsen Schneider, Tadashi Okubo, Christian J. Stoeckert, Jr, Shinji Takada, Mark A. Magnuson
Development. 2014 Aug; 141(15): 2939–2949. doi: 10.1242/dev.104810
PMCID:
PMC4197673
AbstractArticle

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