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Items: 1 to 20 of 86

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Relationship of quantitative reverse transcription polymerase chain reaction (RT-PCR) to RNA Sequencing (RNAseq) transcriptome identifies mouse preimplantation embryo reference genes
Allison K Tscherner, Taylor McClatchie, Angus D Macaulay, Jay M Baltz
Biol Reprod. 2023 Nov; 109(5): 601–617. Published online 2023 Sep 5. doi: 10.1093/biolre/ioad107
PMCID:
PMC10651071
AbstractArticlePDF–2.6M
3.
CCPG1 recognizes endoplasmic reticulum luminal proteins for selective ER-phagy
Shunsuke Ishii, Haruka Chino, Koji L. Ode, Yoshitaka Kurikawa, Hiroki R. Ueda, Akira Matsuura, Noboru Mizushima, Eisuke Itakura
Mol Biol Cell. 2023 Apr 1; 34(4): ar29. Published online 2023 Mar 7. doi: 10.1091/mbc.E22-09-0432
PMCID:
PMC10092646
AbstractArticlePDF–13M
4.
Autophagy inhibition prevents lymphatic malformation progression to lymphangiosarcoma by decreasing osteopontin and Stat3 signaling
Fuchun Yang, Shiva Kalantari, Banzhan Ruan, Shaogang Sun, Zhaoqun Bian, Jun-Lin Guan
Nat Commun. 2023; 14: 978. Published online 2023 Feb 22. doi: 10.1038/s41467-023-36562-5
PMCID:
PMC9946935
AbstractArticlePDF–3.7M
5.
TRIM27 cooperates with STK38L to inhibit ULK1‐mediated autophagy and promote tumorigenesis
Yi Yang, Yifu Zhu, Shuai Zhou, Peipei Tang, Ran Xu, Yuwei Zhang, Dongping Wei, Jian Wen, Rick F Thorne, Xu Dong Zhang, Jun‐Lin Guan, Lianxin Liu, Mian Wu, Song Chen
EMBO J. 2022 Jul; 41(14): e109777. Published online 2022 Jun 7. doi: 10.15252/embj.2021109777
PMCID:
PMC9289709
AbstractArticlePDF–2.3M
6.
Autophagy in PDGFRα+ mesenchymal cells is essential for intestinal stem cell survival
Yang Yang, Maria Gomez, Timothy Marsh, Laura Poillet-Perez, Akshada Sawant, Lei Chen, Noel R. Park, S. RaElle Jackson, Zhixian Hu, Noa Alon, Chen Liu, Jayanta Debnath, Jun-Lin Guan, Shawn Davidson, Michael Verzi, Eileen White
Proc Natl Acad Sci U S A. 2022 May 24; 119(21): e2202016119. Published online 2022 May 10. doi: 10.1073/pnas.2202016119
PMCID:
PMC9173755
AbstractArticlePDF–4.1M
7.
The ATG5 interactome links clathrin-mediated vesicular trafficking with the autophagosome assembly machinery
Kiren Baines, Kazuaki Yoshioka, Yoh Takuwa, Jon D. Lane
Autophagy Rep. 2022; 1(1): 88–118. Published online 2022 Apr 7. doi: 10.1080/27694127.2022.2042054
PMCID:
PMC9015699
AbstractArticlePDF–3.3M
8.
Functional genomic landscape of cancer-intrinsic evasion of killing by T cells
Keith A. Lawson, Cristovão M. Sousa, Xiaoyu Zhang, Eiru Kim, Rummy Akthar, Joseph J. Caumanns, Yuxi Yao, Nicholas Mikolajewicz, Catherine Ross, Kevin R. Brown, Abdelrahman Abou Zid, Zi Peng Fan, Shirley Hui, Jordan A. Krall, Donald M. Simons, Chloe J. Slater, Victor De Jesus, Lujia Tang, Richa Singh, Joshua E. Goldford, Sarah Martin, Qian Huang, Elizabeth A. Francis, Andrea Habsid, Ryan Climie, David Tieu, Jiarun Wei, Ren Li, Amy Hin Yan Tong, Michael Aregger, Katherine S. Chan, Hong Han, Xiaowei Wang, Patricia Mero, John H. Brumell, Antonio Finelli, Laurie Ailles, Gary Bader, Gromoslaw A. Smolen, Gillian A. Kingsbury, Traver Hart, Charles Kung, Jason Moffat
Nature. Author manuscript; available in PMC 2022 Apr 18.
Published in final edited form as: Nature. 2020 Oct; 586(7827): 120–126. Published online 2020 Sep 23. doi: 10.1038/s41586-020-2746-2
PMCID:
PMC9014559
AbstractArticlePDF–6.6M
9.
Non-canonical function of FIP200 is required for neural stem cell maintenance and differentiation by limiting TBK1 activation and p62 aggregate formation
Hang Liu, Chenran Wang, Fei Yi, Syn Yeo, Michael Haas, Xin Tang, Jun-Lin Guan
Sci Rep. 2021; 11: 23907. Published online 2021 Dec 13. doi: 10.1038/s41598-021-03404-7
PMCID:
PMC8668875
AbstractArticlePDF–7.2M
10.
FIP200 restricts RNA virus infection by facilitating RIG-I activation
Lingyan Wang, Kun Song, Wenzhuo Hao, Yakun Wu, Girish Patil, Fang Hua, Yiwen Sun, Chaoqun Huang, Jerry Ritchey, Clinton Jones, Lin Liu, Jun-Lin Guan, Shitao Li
Commun Biol. 2021; 4: 921. Published online 2021 Jul 29. doi: 10.1038/s42003-021-02450-1
PMCID:
PMC8322336
AbstractArticlePDF–3.3M
11.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
12.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
13.
Autophagy Is Required for Maturation of Surfactant-Containing Lamellar Bodies in the Lung and Swim Bladder
Hideaki Morishita, Yuki Kanda, Takeshi Kaizuka, Haruka Chino, Kazuki Nakao, Yoshimi Miki, Yoshitaka Taketomi, Jun-Lin Guan, Makoto Murakami, Atsu Aiba, Noboru Mizushima
Cell Rep. Author manuscript; available in PMC 2020 Dec 29.
Published in final edited form as: Cell Rep. 2020 Dec 8; 33(10): 108477. doi: 10.1016/j.celrep.2020.108477
PMCID:
PMC7770497
AbstractArticlePDF–1.1M
14.
Autophagic adaptation to oxidative stress alters peritoneal residential macrophage survival and ovarian cancer metastasis
Houjun Xia, Shasha Li, Xiong Li, Weichao Wang, Yingjie Bian, Shuang Wei, Sara Grove, Weimin Wang, Linda Vatan, J. Rebecca Liu, Karen McLean, Ramandeep Rattan, Adnan Munkarah, Jun-Lin Guan, Ilona Kryczek, Weiping Zou
JCI Insight. 2020 Sep 17; 5(18): e141115. Published online 2020 Sep 17. doi: 10.1172/jci.insight.141115
PMCID:
PMC7526547
AbstractArticlePDF–4.9M
15.
FIP200 suppresses immune checkpoint therapy responses in breast cancers by limiting AZI2/TBK1/IRF signaling independent of its canonical autophagy function
Takako Okamoto, Syn Kok Yeo, Mingang Hao, Mary Rose Copley, Michael A. Haas, Song Chen, Jun-Lin Guan
Cancer Res. Author manuscript; available in PMC 2021 Mar 1.
Published in final edited form as: Cancer Res. 2020 Sep 1; 80(17): 3580–3592. Published online 2020 Jun 24. doi: 10.1158/0008-5472.CAN-20-0519
PMCID:
PMC7483892
AbstractArticlePDF–2.2M
16.
Autophagic lipid metabolism sustains mTORC1 activity in TSC-deficient neural stem cells
Chenran Wang, Michael A. Haas, Fuchun Yang, Syn Yeo, Takako Okamoto, Song Chen, Jian Wen, Pranjal Sarma, David R. Plas, Jun-Lin Guan
Nat Metab. Author manuscript; available in PMC 2020 Jun 23.
Published in final edited form as: Nat Metab. 2019 Nov; 1(11): 1127–1140. Published online 2019 Nov 11. doi: 10.1038/s42255-019-0137-5
PMCID:
PMC7311104
AbstractArticlePDF–6.8M
17.
Mouse Models of Inherited Retinal Degeneration with Photoreceptor Cell Loss
Gayle B. Collin, Navdeep Gogna, Bo Chang, Nattaya Damkham, Jai Pinkney, Lillian F. Hyde, Lisa Stone, Jürgen K. Naggert, Patsy M. Nishina, Mark P. Krebs
Cells. 2020 Apr; 9(4): 931. Published online 2020 Apr 10. doi: 10.3390/cells9040931
PMCID:
PMC7227028
AbstractArticlePDF–5.4M
18.
Select autophagy genes maintain quiescence of tissue-resident macrophages and increase susceptibility to Listeria monocytogenes
Ya-Ting Wang, Konstantin Zaitsev, Qun Lu, Shan Li, W. Timothy Schaiff, Ki-Wook Kim, Lindsay Droit, Craig B. Wilen, Chandni Desai, Dale R. Balce, Robert C. Orchard, Anthony Orvedahl, Sunmin Park, Darren Kreamalmeyer, Scott A. Handley, John D. Pfeifer, Megan T. Baldridge, Maxim N. Artyomov, Christina L Stallings, Herbert W. Virgin
Nat Microbiol. Author manuscript; available in PMC 2020 Jul 20.
Published in final edited form as: Nat Microbiol. 2020 Feb; 5(2): 272–281. Published online 2020 Jan 20. doi: 10.1038/s41564-019-0633-0
Correction in:
Nat Microbiol. 2021 May 25
PMCID:
PMC7147835
AbstractArticlePDF–4.7M
19.
The autophagy protein, FIP200 (RB1CC1) mediates progesterone responses governing uterine receptivity and decidualization
Arin K Oestreich, Sangappa B Chadchan, Alexandra Medvedeva, John P Lydon, Emily S Jungheim, Kelle H Moley, Ramakrishna Kommagani
Biol Reprod. 2020 Apr; 102(4): 843–851. Published online 2020 Jan 4. doi: 10.1093/biolre/ioz234
PMCID:
PMC7124967
AbstractArticlePDF–1.2M
20.
Atg14 protects the intestinal epithelium from TNF-triggered villus atrophy
Haerin Jung, J. Steven Leal-Ekman, Qiuhe Lu, Thaddeus S. Stappenbeck
Autophagy. 2019; 15(11): 1990–2001. Published online 2019 Apr 3. doi: 10.1080/15548627.2019.1596495
PMCID:
PMC6844524
AbstractArticlePDF–3.0M

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