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Select item 114639691.

Developmental emergence of first- and higher-order thalamic neuron molecular identities

Quentin Lo Giudice, Robin J. Wagener, Philipp Abe, Laura Frangeul, Denis Jabaudon

Development. 2024 Sep 15; 151(18): dev202764. Published online 2024 Sep 30. doi: 10.1242/dev.202764

PMCID:: PMC11463969

Abstract Article

Select item 109176602.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 103078523.

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility

Juan Gu, Pingyang Ke, Haokun Guo, Jing Liu, Yan Liu, Xin Tian, Zhuo Huang, Xin Xu, Demei Xu, Yuanlin Ma, Xuefeng Wang, Fei Xiao

Cell Death Differ. 2023 Jul; 30(7): 1726–1741. Published online 2023 May 4. doi: 10.1038/s41418-023-01174-5

PMCID:: PMC10307852

Abstract Article PDF–8.8M

Select item 94560044.

α₂δ-4 and Cachd1 Proteins Are Regulators of Presynaptic Functions

Cornelia Ablinger, Clarissa Eibl, Stefanie M. Geisler, Marta Campiglio, Gary J. Stephens, Markus Missler, Gerald J. Obermair

Int J Mol Sci. 2022 Sep; 23(17): 9885. Published online 2022 Aug 31. doi: 10.3390/ijms23179885

PMCID:: PMC9456004

Abstract Article PDF–4.0M

Select item 90347535.

Impaired Subcortical Processing of Amplitude-Modulated Tones in Mice Deficient for Cacna2d3, a Risk Gene for Autism Spectrum Disorders in Humans

Gerhard Bracic, Katrin Hegmann, Jutta Engel, Simone Kurt

eNeuro. 2022 Mar-Apr; 9(2): ENEURO.0118-22.2022. Prepublished online 2022 Apr 11. Published online 2022 Apr 21. doi: 10.1523/ENEURO.0118-22.2022

PMCID:: PMC9034753

Abstract Article PDF–1.0M

Select item 83132396.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 80408237.

Presynaptic α₂δ subunits are key organizers of glutamatergic synapses

Clemens L. Schöpf, Cornelia Ablinger, Stefanie M. Geisler, Ruslan I. Stanika, Marta Campiglio, Walter A. Kaufmann, Benedikt Nimmervoll, Bettina Schlick, Johannes Brockhaus, Markus Missler, Ryuichi Shigemoto, Gerald J. Obermair

Proc Natl Acad Sci U S A. 2021 Apr 6; 118(14): e1920827118. Published online 2021 Mar 29. doi: 10.1073/pnas.1920827118

PMCID:: PMC8040823

Abstract Article PDF–2.4M

Select item 73263588.

Auxiliary α2δ1 and α2δ3 Subunits of Calcium Channels Drive Excitatory and Inhibitory Neuronal Network Development

Arthur Bikbaev, Anna Ciuraszkiewicz-Wojciech, Jennifer Heck, Oliver Klatt, Romy Freund, Jessica Mitlöhner, Sara Enrile Lacalle, Miao Sun, Daniele Repetto, Renato Frischknecht, Cornelia Ablinger, Astrid Rohlmann, Markus Missler, Gerald J. Obermair, Valentina Di Biase, Martin Heine

J Neurosci. 2020 Jun 17; 40(25): 4824–4841. doi: 10.1523/JNEUROSCI.1707-19.2020

PMCID:: PMC7326358

Abstract Article PDF–5.9M

Select item 67822069.

Molecular Diversity of the Calcium Channel α₂δ Subunit

Norbert Klugbauer, Lubica Lacinová, Elsé Marais, Muriel Hobom, Franz Hofmann

J Neurosci. 1999 Jan 15; 19(2): 684–691. doi: 10.1523/JNEUROSCI.19-02-00684.1999

PMCID:: PMC6782206

Abstract Article PDF–299K

Select item 660815210.

α₂δ3 Is Essential for Normal Structure and Function of Auditory Nerve Synapses and Is a Novel Candidate for Auditory Processing Disorders

Antonella Pirone, Simone Kurt, Annalisa Zuccotti, Lukas Rüttiger, Peter Pilz, David H. Brown, Christoph Franz, Michaela Schweizer, Marco B. Rust, Rudolf Rübsamen, Eckhard Friauf, Marlies Knipper, Jutta Engel

J Neurosci. 2014 Jan 8; 34(2): 434–445. doi: 10.1523/JNEUROSCI.3085-13.2014

PMCID:: PMC6608152

Abstract Article PDF–2.4M

Select item 660670611.

Deletion of the Ca²⁺ Channel Subunit α₂δ3 Differentially Affects Ca_v2.1 and Ca_v2.2 Currents in Cultured Spiral Ganglion Neurons Before and After the Onset of Hearing

Friederike Stephani, Veronika Scheuer, Tobias Eckrich, Kerstin Blum, Wenying Wang, Gerald J. Obermair, Jutta Engel

Front Cell Neurosci. 2019; 13: 278. Published online 2019 Jun 26. doi: 10.3389/fncel.2019.00278

PMCID:: PMC6606706

Abstract Article PDF–4.6M

Select item 644598712.

Presynaptic α₂δ-2 Calcium Channel Subunits Regulate Postsynaptic GABA_A Receptor Abundance and Axonal Wiring

Stefanie Geisler, Clemens L. Schöpf, Ruslan Stanika, Marcus Kalb, Marta Campiglio, Daniele Repetto, Larissa Traxler, Markus Missler, Gerald J. Obermair

J Neurosci. 2019 Apr 3; 39(14): 2581–2605. doi: 10.1523/JNEUROSCI.2234-18.2019

PMCID:: PMC6445987

Abstract Article PDF–8.6M

Select item 619146013.

MicroRNA-27a controls the intracellular survival of Mycobacterium tuberculosis by regulating calcium-associated autophagy

Feng Liu, Jianxia Chen, Peng Wang, Haohao Li, Yilong Zhou, Haipeng Liu, Zhonghua Liu, Ruijuan Zheng, Lin Wang, Hua Yang, Zhenling Cui, Fei Wang, Xiaochen Huang, Jie Wang, Wei Sha, Heping Xiao, Baoxue Ge

Nat Commun. 2018; 9: 4295. Published online 2018 Oct 16. doi: 10.1038/s41467-018-06836-4

PMCID:: PMC6191460

Abstract Article PDF–4.8M

Select item 550326114.

Systematic screening for skin, hair, and nail abnormalities in a large-scale knockout mouse program

John P. Sundberg, Soheil S. Dadras, Kathleen A. Silva, Victoria E. Kennedy, Gaven Garland, Stephen A. Murray, Beth A. Sundberg, Paul N. Schofield, C. Herbert Pratt

PLoS One. 2017; 12(7): e0180682. Published online 2017 Jul 10. doi: 10.1371/journal.pone.0180682

PMCID:: PMC5503261

Abstract Article PDF–31M

Select item 544174015.

Murine model indicates 22q11.2 signaling adaptor CRKL is a dosage-sensitive regulator of genitourinary development

Meade Haller, Qianxing Mo, Akira Imamoto, Dolores J. Lamb

Proc Natl Acad Sci U S A. 2017 May 9; 114(19): 4981–4986. Published online 2017 Apr 24. doi: 10.1073/pnas.1619523114

PMCID:: PMC5441740

Abstract Article PDF–3.0M

Select item 529582116.

High-throughput discovery of novel developmental phenotypes

Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray

Nature. Author manuscript; available in PMC 2017 Mar 14.

Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356

Correction in:: Nature. 2017 Nov 16; 551(7680): 398.

PMCID:: PMC5295821

Abstract Article PDF–3.0M

Select item 506516217.

Coordinately Co-opted Multiple Transposable Elements Constitute an Enhancer for wnt5a Expression in the Mammalian Secondary Palate

Hidenori Nishihara, Naoki Kobayashi, Chiharu Kimura-Yoshida, Kuo Yan, Olga Bormuth, Qiong Ding, Akiko Nakanishi, Takeshi Sasaki, Mika Hirakawa, Kenta Sumiyama, Yasuhide Furuta, Victor Tarabykin, Isao Matsuo, Norihiro Okada

PLoS Genet. 2016 Oct; 12(10): e1006380. Published online 2016 Oct 14. doi: 10.1371/journal.pgen.1006380

PMCID:: PMC5065162

Abstract Article PDF–3.4M

Select item 431955918.

A high resolution spatiotemporal atlas of gene expression of the developing mouse brain

Carol L. Thompson, Lydia Ng, Vilas Menon, Salvador Martinez, Chang-Kyu Lee, Katie Glattfelder, Susan M. Sunkin, Alex Henry, Christopher Lau, Chinh Dang, Raquel Garcia-Lopez, Almudena Martinez-Ferre, Ana Pombero, John L.R. Rubenstein, Wayne B. Wakeman, John Hohmann, Nick Dee, Andrew J. Sodt, Rob Young, Kimberly Smith, Thuc-Nghi Nguyen, Jolene Kidney, Leonard Kuan, Andreas Jeromin, Ajamete Kaykas, Jeremy Miller, Damon Page, Geri Orta, Amy Bernard, Zackery Riley, Simon Smith, Paul Wohnoutka, Mike Hawrylycz, Luis Puelles, Allan R. Jones

Neuron. Author manuscript; available in PMC 2015 Jul 16.

Published in final edited form as: Neuron. 2014 Jul 16; 83(2): 309–323. Published online 2014 Jun 19. doi: 10.1016/j.neuron.2014.05.033

PMCID:: PMC4319559

Abstract Article PDF–3.0M

Select item 396495519.

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data

Gautier Koscielny, Gagarine Yaikhom, Vivek Iyer, Terrence F. Meehan, Hugh Morgan, Julian Atienza-Herrero, Andrew Blake, Chao-Kung Chen, Richard Easty, Armida Di Fenza, Tanja Fiegel, Mark Grifiths, Alan Horne, Natasha A. Karp, Natalja Kurbatova, Jeremy C. Mason, Peter Matthews, Darren J. Oakley, Asfand Qazi, Jack Regnart, Ahmad Retha, Luis A. Santos, Duncan J. Sneddon, Jonathan Warren, Henrik Westerberg, Robert J. Wilson, David G. Melvin, Damian Smedley, Steve D. M. Brown, Paul Flicek, William C. Skarnes, Ann-Marie Mallon, Helen Parkinson

Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D802–D809. Published online 2013 Nov 3. doi: 10.1093/nar/gkt977

PMCID:: PMC3964955

Abstract Article PDF–5.7M

Select item 389830020.

Differential Neuronal Targeting of a New and Two Known Calcium Channel β₄ Subunit Splice Variants Correlates with Their Regulation of Gene Expression

Solmaz Etemad, Gerald J. Obermair, Daniel Bindreither, Ariane Benedetti, Ruslan Stanika, Valentina Di Biase, Verena Burtscher, Alexandra Koschak, Reinhard Kofler, Stephan Geley, Alexandra Wille, Alexandra Lusser, Veit Flockerzi, Bernhard E. Flucher

J Neurosci. 2014 Jan 22; 34(4): 1446–1461. doi: 10.1523/JNEUROSCI.3935-13.2014

PMCID:: PMC3898300

Abstract Article PDF–4.4M

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