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Items: 1 to 20 of 26

1.
G-Protein-Coupled Receptor 91-Dependent Signalling Does Not Influence Vascular Inflammation and Atherosclerosis in Hyperlipidaemic Mice
Silke Griepke, Mette Trauelsen, Michelle D. Nilsson, Jakob Hansen, Lasse B. Steffensen, Thue W. Schwartz, Daniel F. J. Ketelhuth
Cells. 2023 Nov; 12(21): 2580. Published online 2023 Nov 6. doi: 10.3390/cells12212580
PMCID:
PMC10647868
AbstractArticlePDF–3.9M
2.
A succinate/SUCNR1-brush cell defense program in the tracheal epithelium
Alexander Perniss, Brett Boonen, Sarah Tonack, Moritz Thiel, Krupali Poharkar, Mohamad Wessam Alnouri, Maryam Keshavarz, Tamara Papadakis, Silke Wiegand, Uwe Pfeil, Katrin Richter, Mike Althaus, Johannes Oberwinkler, Burkhard Schütz, Ulrich Boehm, Stefan Offermanns, Trese Leinders-Zufall, Frank Zufall, Wolfgang Kummer
Sci Adv. 2023 Aug; 9(31): eadg8842. Published online 2023 Aug 2. doi: 10.1126/sciadv.adg8842
PMCID:
PMC10396310
AbstractArticlePDF–2.6M
3.
Targeting the succinate receptor effectively inhibits periodontitis
Yuqi Guo, Fangxi Xu, Scott C. Thomas, Yanli Zhang, Bidisha Paul, Satish Sakilam, Sungpil Chae, Patty Li, Caleb Almeter, Angela R. Kamer, Paramjit Arora, Dana T. Graves, Deepak Saxena, Xin Li
Cell Rep. Author manuscript; available in PMC 2022 Oct 5.
Published in final edited form as: Cell Rep. 2022 Sep 20; 40(12): 111389. doi: 10.1016/j.celrep.2022.111389
PMCID:
PMC9533417
AbstractArticlePDF–2.4M
4.
Enteric helminth coinfection enhances host susceptibility to neurotropic flaviviruses via a tuft cell-IL-4 receptor signaling axis
Pritesh Desai, Hana Janova, James P. White, Glennys V. Reynoso, Heather D. Hickman, Megan T. Baldridge, Joseph F. Urban, Jr., Thaddeus S. Stappenbeck, Larissa B. Thackray, Michael S. Diamond
Cell. Author manuscript; available in PMC 2022 Mar 4.
Published in final edited form as: Cell. 2021 Mar 4; 184(5): 1214–1231.e16. Published online 2021 Feb 25. doi: 10.1016/j.cell.2021.01.051
PMCID:
PMC7962748
AbstractArticlePDF–2.4M
5.
pH-Gated Succinate Secretion Regulates Muscle Remodeling in Response to Exercise
Anita Reddy, Luiz H.M. Bozi, Omar K. Yaghi, Evanna L. Mills, Haopeng Xiao, Hilary E. Nicholson, Margherita Paschini, Joao A. Paulo, Ryan Garrity, Dina Laznik-Bogoslavski, Julio C.B. Ferreira, Christian S. Carl, Kim A. Sjøberg, Jørgen Wojtaszewski, Jacob F. Jeppesen, Bente Kiens, Steven P. Gygi, Erik A. Richter, Diane Mathis, Edward T. Chouchani
Cell. Author manuscript; available in PMC 2021 Oct 1.
Published in final edited form as: Cell. 2020 Oct 1; 183(1): 62–75.e17. Published online 2020 Sep 17. doi: 10.1016/j.cell.2020.08.039
PMCID:
PMC7778787
AbstractArticlePDF–1.8M
6.
Succinate induces skeletal muscle fiber remodeling via SUNCR1 signaling
Tao Wang, Ya‐Qiong Xu, Ye‐Xian Yuan, Ping‐Wen Xu, Cha Zhang, Fan Li, Li‐Na Wang, Cong Yin, Lin Zhang, Xing‐Cai Cai, Can‐Jun Zhu, Jing‐Ren Xu, Bing‐Qing Liang, Sarah Schaul, Pei‐Pei Xie, Dong Yue, Zheng‐Rui Liao, Lu‐Lu Yu, Lv Luo, Gan Zhou, Jin‐Ping Yang, Zhi‐Hui He, Man Du, Yu‐Ping Zhou, Bai‐Chuan Deng, Song‐Bo Wang, Ping Gao, Xiao‐Tong Zhu, Qian‐Yun Xi, Yong‐Liang Zhang, Gang Shu, Qing‐Yan Jiang
EMBO Rep. 2019 Sep; 20(9): e47892. Published online 2019 Jul 18. doi: 10.15252/embr.201947892
Correction in:
EMBO Rep. 2020 May 6; 21(5): e50461.
Correction in:
EMBO Rep. 2021 Jun 4; 22(6): e53027.
PMCID:
PMC6727026
AbstractArticlePDF–4.1M
7.
Detection of succinate by intestinal tuft cells triggers a type 2 innate immune circuit
Marija S. Nadjsombati, John W. McGinty, Miranda R. Lyons-Cohen, James B. Jaffe, Lucian DiPeso, Christoph Schneider, Corey N. Miller, Joshua L. Pollack, G.A. Nagana Gowda, Mary F. Fontana, David J. Erle, Mark S. Anderson, Richard M. Locksley, Daniel Raftery, Jakob von Moltke
Immunity. Author manuscript; available in PMC 2019 Jul 17.
Published in final edited form as: Immunity. 2018 Jul 17; 49(1): 33–41.e7. doi: 10.1016/j.immuni.2018.06.016
PMCID:
PMC6084797
AbstractArticlePDF–1.0M
8.
Activation of intestinal tuft cell-expressed Sucnr1 triggers type 2 immunity in the mouse small intestine
Weiwei Lei, Wenwen Ren, Makoto Ohmoto, Joseph F. Urban, Jr., Ichiro Matsumoto, Robert F. Margolskee, Peihua Jiang
Proc Natl Acad Sci U S A. 2018 May 22; 115(21): 5552–5557. Published online 2018 May 7. doi: 10.1073/pnas.1720758115
PMCID:
PMC6003470
AbstractArticlePDF–1.3M
9.
Succinate induces aberrant mitochondrial fission in cardiomyocytes through GPR91 signaling
Yi-Tong Lu, Lan-Zhu Li, Yi-Lin Yang, Xiaojian Yin, Qun Liu, Lei Zhang, Kang Liu, Baolin Liu, Jia Li, Lian-Wen Qi
Cell Death Dis. 2018 Jun; 9(6): 672. Published online 2018 Jun 4. doi: 10.1038/s41419-018-0708-5
PMCID:
PMC5986788
AbstractArticlePDF–2.8M
10.
Receptors of intermediates of carbohydrate metabolism, GPR91 and GPR99, mediate axon growth
Hosni Cherif, François Duhamel, Bruno Cécyre, Alex Bouchard, Ariane Quintal, Sylvain Chemtob, Jean-François Bouchard
PLoS Biol. 2018 May; 16(5): e2003619. Published online 2018 May 17. doi: 10.1371/journal.pbio.2003619
PMCID:
PMC5976209
AbstractArticlePDF–5.2M
11.
SUCNR1-mediated chemotaxis of macrophages aggravates obesity-induced inflammation and diabetes
Janna A. van Diepen, Joris H. Robben, Guido J. Hooiveld, Claudia Carmone, Mohammad Alsady, Lily Boutens, Melissa Bekkenkamp-Grovenstein, Anneke Hijmans, Udo F. H. Engelke, Ron A. Wevers, Mihai G. Netea, Cees J. Tack, Rinke Stienstra, Peter M. T. Deen
Diabetologia. 2017; 60(7): 1304–1313. Published online 2017 Apr 5. doi: 10.1007/s00125-017-4261-z
PMCID:
PMC5487589
AbstractArticlePDF–990K
12.
Succinate and its G-protein-coupled receptor stimulates osteoclastogenesis
Yuqi Guo, Chengzhi Xie, Xiyan Li, Jian Yang, Tao Yu, Ruohan Zhang, Tianqing Zhang, Deepak Saxena, Michael Snyder, Yingjie Wu, Xin Li
Nat Commun. 2017; 8: 15621. Published online 2017 May 31. doi: 10.1038/ncomms15621
PMCID:
PMC5460032
AbstractArticlePDF–3.4M
13.
GPR91 deficiency exacerbates allergic contact dermatitis while reducing arthritic disease in mice
T. Rubić‐Schneider, N. Carballido‐Perrig, C. Regairaz, L. Raad, S. Jost, C. Rauld, B. Christen, G. Wieczorek, R. Kreutzer, J. Dawson, G. Lametschwandner, A. Littlewood‐Evans, J. M. Carballido
Allergy. 2017 Mar; 72(3): 444–452. Published online 2016 Sep 12. doi: 10.1111/all.13005
PMCID:
PMC5324651
AbstractArticlePDF–917K
14.
GPR91 senses extracellular succinate released from inflammatory macrophages and exacerbates rheumatoid arthritis
Amanda Littlewood-Evans, Sophie Sarret, Verena Apfel, Perrine Loesle, Janet Dawson, Juan Zhang, Alban Muller, Bruno Tigani, Rainer Kneuer, Saijel Patel, Stephanie Valeaux, Nina Gommermann, Tina Rubic-Schneider, Tobias Junt, José M. Carballido
J Exp Med. 2016 Aug 22; 213(9): 1655–1662. doi: 10.1084/jem.20160061
PMCID:
PMC4995082
AbstractArticlePDF–1.5M
15.
Succinate causes pathological cardiomyocyte hypertrophy through GPR91 activation
Carla J Aguiar, João A Rocha-Franco, Pedro A Sousa, Anderson K Santos, Marina Ladeira, Cibele Rocha-Resende, Luiz O Ladeira, Rodrigo R Resende, Fernando A Botoni, Marcos Barrouin Melo, Cristiano X Lima, José M Carballido, Thiago M Cunha, Gustavo B Menezes, Silvia Guatimosim, M Fatima Leite
Cell Commun Signal. 2014; 12: 78. Published online 2014 Dec 24. doi: 10.1186/s12964-014-0078-2
PMCID:
PMC4296677
AbstractArticlePDF–3.6M
16.
Deficiency in the metabolite receptor SUCNR1 (GPR91) leads to outer retinal lesions
Sandra Favret, Francois Binet, Eric Lapalme, Dominique Leboeuf, Jose Carbadillo, Tina Rubic, Emilie Picard, Gaelle Mawambo, Nicolas Tetreault, Jean-Sebastien Joyal, Sylvain Chemtob, Florian Sennlaub, John Paul SanGiovanni, Martin Guimond, Przemyslaw Sapieha
Aging (Albany NY) 2013 Jun; 5(6): 427–444. Published online 2013 Jun 17. doi: 10.18632/aging.100563
PMCID:
PMC3832265
AbstractArticlePDF–4.2M
17.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
18.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
19.
Expression and Iron-Dependent Regulation of Succinate Receptor GPR91 in Retinal Pigment Epithelium
Jaya P. Gnana-Prakasam, Sudha Ananth, Puttur D. Prasad, Ming Zhang, Sally S. Atherton, Pamela M. Martin, Sylvia B. Smith, Vadivel Ganapathy
Invest Ophthalmol Vis Sci. 2011 May; 52(6): 3751–3758. Published online 2011 May 31. doi: 10.1167/iovs.10-6722
PMCID:
PMC3109050
AbstractArticlePDF–1.3M
20.
A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo
Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio
PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582
PMCID:
PMC3022534
AbstractArticlePDF–3.8M

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